Reactive oxygen species (ROS) as Elixirs against chronic Disease: OXidative regulatory mechanisms In T cells and neutrophils.

Información del proyecto

REDOXIT

Identificador del acuerdo de subvención: 644035

DOI

10.3030/644035

Proyecto cerrado

Fecha de la firma de la CE 5 Noviembre 2014

Fecha de inicio 1 Julio 2015

Fecha de finalización 30 Junio 2019

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 144 000,00

Aportación de la UE

€ 144 000,00

Coordinado por

UNIVERSITY OF SURREY
United Kingdom

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Other (3)

Summer School on advances in free radical research

The Summer School will be open to all citizens and will be organised in conjunction with other organisations eg the Society for Free Radical Research Europe SFRRE of which Griffiths on the Executive Committee New advances in understanding of the role of redox state in chronic disease and how to manipulate them will be a focus of this meeting The advantages of activating and inhibiting NOX will be highlighted Participants from each centre will participate in the summer School through poster and flash presentations

Open workshop on inter-sectoral drug development

The goal of this workshop is to provide a forum for development of new collaborations and for maximising knowledge transfer opportunities. EU officers will be invited to gain insight into the project development and its achievement of objectives in knowledge transfer.

Winter School on cell analysis

The Winter School will be open to all citizens and will be organised in conjunction with other organisations eg the Biochemical Society of which Griffiths is on the Metabolism Theme Panel The advances in specificity and sensitivity of methods for measuring changes in redox state will be highlighted Particular attention will be paid towards validation of analytical tools in biological samples

Publicaciones

Peer reviewed articles (4)

The dual role of ROS in autoimmune and inflammatory diseases: Evidence from preclinical models

Autores: Markus H. Hoffmann, Helen R. Griffiths
Publicado en: Free Radical Biology and Medicine, 2018, ISSN 0891-5849
Editor: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2018.03.016

Chemical Tools for Targeted Amplification of Reactive Oxygen Species in Neutrophils

Autores: Viktor Reshetnikov, Jonas Hahn, Christian Maueröder, Christine Czegley, Luis Enrique Munoz, Martin Herrmann, Markus H. Hoffmann, Andriy Mokhir
Publicado en: Frontiers in Immunology, Edición 9, 2018, ISSN 1664-3224
Editor: Frontiers
DOI: 10.3389/fimmu.2018.01827

NOX2 mediates quiescent handling of dead cell remnants in phagocytes

Autores: Jonas Hahn, Maximilien Euler, Emelie Kilgus, Deborah Kienhöfer, Julia Stoof, Jasmin Knopf, Madelaine Hahn, Thomas Harrer, Malin Hultqvist, Peter Olofsson, Andriy Mokhir, Rikard Holmdahl, Martin Herrmann, Georg Schett, Luis E. Muñoz, Markus H. Hoffmann
Publicado en: Redox Biology, Edición 26, 2019, Página(s) 101279, ISSN 2213-2317
Editor: Elsevier BV
DOI: 10.1016/j.redox.2019.101279

Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps

Autores: Deborah Kienhöfer, Jonas Hahn, Julia Stoof, Janka Zsófia Csepregi, Christiane Reinwald, Vilma Urbonaviciute, Caroline Johnsson, Christian Maueröder, Malgorzata J. Podolska, Mona H. Biermann, Moritz Leppkes, Thomas Harrer, Malin Hultqvist, Peter Olofsson, Luis E. Munoz, Attila Mocsai, Martin Herrmann, Georg Schett, Rikard Holmdahl, Markus H. Hoffmann
Publicado en: JCI Insight, Edición 2/10, 2017, Página(s) e92920, ISSN 2379-3708
Editor: American Society for Clinical Investigation
DOI: 10.1172/jci.insight.92920