Reactive oxygen species (ROS) as Elixirs against chronic Disease: OXidative regulatory mechanisms In T cells and neutrophils.

Informazioni relative al progetto

REDOXIT

ID dell’accordo di sovvenzione: 644035

DOI

10.3030/644035

Progetto chiuso

Data della firma CE 5 Novembre 2014

Data di avvio 1 Luglio 2015

Data di completamento 30 Giugno 2019

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale

€ 144 000,00

Contributo UE

€ 144 000,00

Coordinato da

UNIVERSITY OF SURREY
United Kingdom

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I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Other (3)

Summer School on advances in free radical research

The Summer School will be open to all citizens and will be organised in conjunction with other organisations eg the Society for Free Radical Research Europe SFRRE of which Griffiths on the Executive Committee New advances in understanding of the role of redox state in chronic disease and how to manipulate them will be a focus of this meeting The advantages of activating and inhibiting NOX will be highlighted Participants from each centre will participate in the summer School through poster and flash presentations

Open workshop on inter-sectoral drug development

The goal of this workshop is to provide a forum for development of new collaborations and for maximising knowledge transfer opportunities. EU officers will be invited to gain insight into the project development and its achievement of objectives in knowledge transfer.

Winter School on cell analysis

The Winter School will be open to all citizens and will be organised in conjunction with other organisations eg the Biochemical Society of which Griffiths is on the Metabolism Theme Panel The advances in specificity and sensitivity of methods for measuring changes in redox state will be highlighted Particular attention will be paid towards validation of analytical tools in biological samples

Pubblicazioni

Peer reviewed articles (4)

The dual role of ROS in autoimmune and inflammatory diseases: Evidence from preclinical models

Autori: Markus H. Hoffmann, Helen R. Griffiths
Pubblicato in: Free Radical Biology and Medicine, 2018, ISSN 0891-5849
Editore: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2018.03.016

Chemical Tools for Targeted Amplification of Reactive Oxygen Species in Neutrophils

Autori: Viktor Reshetnikov, Jonas Hahn, Christian Maueröder, Christine Czegley, Luis Enrique Munoz, Martin Herrmann, Markus H. Hoffmann, Andriy Mokhir
Pubblicato in: Frontiers in Immunology, Numero 9, 2018, ISSN 1664-3224
Editore: Frontiers
DOI: 10.3389/fimmu.2018.01827

NOX2 mediates quiescent handling of dead cell remnants in phagocytes

Autori: Jonas Hahn, Maximilien Euler, Emelie Kilgus, Deborah Kienhöfer, Julia Stoof, Jasmin Knopf, Madelaine Hahn, Thomas Harrer, Malin Hultqvist, Peter Olofsson, Andriy Mokhir, Rikard Holmdahl, Martin Herrmann, Georg Schett, Luis E. Muñoz, Markus H. Hoffmann
Pubblicato in: Redox Biology, Numero 26, 2019, Pagina/e 101279, ISSN 2213-2317
Editore: Elsevier BV
DOI: 10.1016/j.redox.2019.101279

Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps

Autori: Deborah Kienhöfer, Jonas Hahn, Julia Stoof, Janka Zsófia Csepregi, Christiane Reinwald, Vilma Urbonaviciute, Caroline Johnsson, Christian Maueröder, Malgorzata J. Podolska, Mona H. Biermann, Moritz Leppkes, Thomas Harrer, Malin Hultqvist, Peter Olofsson, Luis E. Munoz, Attila Mocsai, Martin Herrmann, Georg Schett, Rikard Holmdahl, Markus H. Hoffmann
Pubblicato in: JCI Insight, Numero 2/10, 2017, Pagina/e e92920, ISSN 2379-3708
Editore: American Society for Clinical Investigation
DOI: 10.1172/jci.insight.92920