Obiettivo The health of livestock is commonly impacted by viruses acquired from midge vectors. The viruses transferred following a midge bite cause considerable economic losses across the EU, making control of midges/midge vector competence a pressing concern. Recent research has indicated some inherited symbionts may alter the vector competence of their insect host, and thus represent viable means of interrupting pathogen transmission in natural populations. However, reduction of vector competence has only been considered for Wolbachia symbiont infections, and for viruses of importance to human health. Midges, in contrast, are commonly infected with a Cardinium heritable symbiont with unknown properties. This project seeks to establish tools for understanding this symbiont, and investigate whether it affects host immune system activity and vector competence following exposure to an infected blood meal. This proposal will thus provide both fundamental understanding of a poorly studied symbiont in an important host group, and, more practically, evaluate whether alteration of symbiont presence is a viable means of interrupting viral transmission. Campo scientifico natural sciencesbiological sciencesmicrobiologybacteriologynatural sciencesbiological sciencesmicrobiologyvirologyagricultural sciencesanimal and dairy sciencedomestic animalsanimal husbandrynatural sciencesbiological sciencesgeneticsgenomesnatural sciencesbiological scienceszoologyinvertebrate zoology Programma(i) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Argomento(i) MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) Invito a presentare proposte H2020-MSCA-IF-2014 Vedi altri progetti per questo bando Meccanismo di finanziamento MSCA-IF-EF-ST - Standard EF Coordinatore THE UNIVERSITY OF LIVERPOOL Contribution nette de l'UE € 183 454,80 Indirizzo BROWNLOW HILL 765 FOUNDATION BUILDING L69 7ZX Liverpool Regno Unito Mostra sulla mappa Regione North West (England) Merseyside Liverpool Tipo di attività Higher or Secondary Education Establishments Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Partecipazione a programmi di R&I dell'UE Opens in new window Rete di collaborazione HORIZON Opens in new window Costo totale € 183 454,80
