Ziel
Depression is a leading cause of disability and produces a greater decrement in health than other common chronic diseases such as angina, arthritis, asthma and diabetes. In Europe, it is estimated that 7.2% of the disease burden is caused by depression with associated costs of €118 billion. It generally takes months before clinicians are able to identify an effective antidepressant treatment for individual patients and during this period a patients’ ability to work and function socially is severely impaired by their illness. We will address this problem using the Primary Care –Emotional Test Battery (PC-ETB) a medical device that is sensitive to changes in negative emotional bias, an early biomarker for the effectiveness of antidepressant treatment. Identifying early, rather than late in treatment, if an antidepressant is working will significantly reduce the time required for the patient to get better and return to normal life. The PC-ETB has been developed from a more extensive product battery that we provide to the pharmaceutical industry for drug development. In Phase 1 we will: (i) Assess the feasibility of using the PC-ETB in primary care in Europe; (ii) Determine how to set up a multinational medical device clinical investigation in Europe; (iii) Expand a health economic assessment conducted in the UK to include other major European countries and demonstrate the healthcare and societal benefits across Europe; (iv) Develop a commercialisation strategy across the major European countries by conducting a market research assessment of the market size, route to adoption, pricing and reimbursement mechanisms. In Phase 2 of the project we will conduct clinical validation of multi-lingual versions of the PC-ETB in a number of European countries. This innovative project is designed to complete the clinical validation of the PC-ETB and enable its launch as an internet delivered product to improve the management and treatment of depression across the European market.
Wissenschaftliches Gebiet
- medical and health sciencesbasic medicinepharmacology and pharmacydrug discovery
- medical and health scienceshealth scienceshealth care serviceseHealth
- medical and health sciencesclinical medicinepneumologyasthma
- medical and health sciencesclinical medicinerheumatology
- medical and health sciencesclinical medicineendocrinologydiabetes
Programm/Programme
Thema/Themen
Aufforderung zur Vorschlagseinreichung
Andere Projekte für diesen Aufruf anzeigenUnterauftrag
H2020-SMEINST-1-2014
Finanzierungsplan
SME-1 - SME instrument phase 1Koordinator
OX10 8BA Wallingford
Vereinigtes Königreich
Die Organisation definierte sich zum Zeitpunkt der Unterzeichnung der Finanzhilfevereinbarung selbst als KMU (Kleine und mittlere Unternehmen).