INnovative Life sCIence Phd Programme in South ITaly

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Publication of call 1 sent to Project Officer

Publication of call 1 sent to Project Officer (M1)

Publication of call 2 sent to Project Officer

Pubblicazioni

Targeting Mitochondrial Network Architecture in Down Syndrome and Aging

Autori: Mollo N, Cicatiello R, Aurilia M, Scognamiglio R, Genesio R, Charalambous M, Paladino S, Conti A, Nitsch L, Izzo A.
Pubblicato in: International Journal of Molecular Sciences, 2020, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21093134

The non-swapped monomeric structure of the arginine-binding protein from Thermotoga maritima. Acta Crystallogr F Struct Biol Commun

Autori: Smaldone, G, Ruggiero, A, Balasco, N, Abuhammad, A, Autiero, I, Caruso, D, Esposito, D, Ferraro, G, Gelardi, E. L. M, Moreira, M, Quareshy, M, Romano, M, Saaret, A, Selvam, I, Squeglia, F, Troisi, R, Kroon-Batenburg, L. M. J, Esposito, L, Berisio, R, Vitagliano, L.
Pubblicato in: Acta Crystallogr F Struct Biol Commun, Numero 9, 2019, Pagina/e 707-713, ISSN 2053-230X
Editore: John Wiley and Sons Ltd
DOI: 10.1107/s2053230x1901464x

2. Sara Kebbi; Maria Letizia Ciavatta; Ali M. Mahmoud; Marianna Carbone; Alessia Ligresti; Ramdane Seghiri; Margherita Gavagnin

Autori: Sara Kebbi; Maria Letizia Ciavatta; Ali M. Mahmoud; Marianna Carbone; Alessia Ligresti; Ramdane Seghiri; Margherita Gavagnin
Pubblicato in: Biomolecules, 2021, ISSN 2218-273X
Editore: PubMed
DOI: 10.3390/biom11071053

Network Distances for Weighted Digraphs

Autori: Granata, I., Guarracino, M.R., Maddalena, L., Manipur, I.
Pubblicato in: Communications in Computer and Information Science, 2020, ISSN 1012-2443
Editore: Kluwer Academic Publishers
DOI: 10.1007/s10472-019-09640-y

The phenotypic variations of multi-locus imprinting disturbances associated with maternal-effect variants of NLRP5 range from overt imprinting disorder to apparently healthy phenotype

Autori: Sparago A, Verma A, Patricelli MG, Pignata L, Russo S, Calzari L, De Francesco N, Del Prete R, Palumbo O, Carella M, Mackay DJG, Rezwan FI, Angelini C, Cerrato F, Cubellis MV, Riccio A.
Pubblicato in: Clinical Epigenetics, 2019, ISSN 1868-7083
Editore: BMC - Springer
DOI: 10.1186/s13148-019-0760-8

Fishing for Targets of Alien Metabolites: A Novel Peroxisome Proliferator-Activated Receptor (PPAR) Agonist from a Marine Pest

Autori: Vitale, Rosa; D'Aniello, Enrico; Gorbi, Stefania; Martella, Andrea; Silvestri, Cristoforo; Giuliani, Maria; Fellous, Tariq; Gentile, Alessandra; Carbone, Marianna; Cutignano, Adele; Grauso, Laura; Magliozzi, Laura; Polese, Gianluca; D'Aniello, Biagio; Defranoux, Fanny; Felline, Serena; Terlizzi, Antonio; Calignano, Antonio; Regoli, Francesco; Di Marzo, Vincenzo; Amodeo, Pietro; Mollo, Ernesto
Pubblicato in: Marine Drugs, Vol 16, Iss 11, p 431 (2018), Numero 4, 2018, ISSN 1660-3397
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/md16110431

Design, Synthesis, and Physicochemical and Pharmacological Profiling of 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Derivatives with Antiosteoarthritic Activity In Vivo

Autori: Claudia Mugnaini, Magdalena Kostrzewa, Marta Bryk, Ali Mokhtar Mahmoud, Antonella Brizzi, Stefania Lamponi, Gianluca Giorgi, Francesca Ferlenghi, Federica Vacondio, Paola Maccioni, Giancarlo Colombo, Marco Mor, Katarzyna Starowicz, Vincenzo Di Marzo, Alessia Ligresti, Federico Corelli.
Pubblicato in: J. Med. Chem., 2020, Pagina/e 7369–7391, ISSN 0022-2623
Editore: American Chemical Society
DOI: 10.1021/acs.jmedchem.0c00595

Long non-coding RNA MAGI2-AS3 is a new player with a tumor suppressive role in High Grade Serous Carcinoma

Autori: Priyanka Gokulnath, Tiziana de Cristofaro, Ichcha Manipur, Tina di Palma, Amy Amata Soriano, Mario Guarracino, Mariastella Zannini
Pubblicato in: Cancers (basel), 2019, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11122008

Acrolein and Copper as Competitive Effectors of α-Synuclein

Autori: Falcone, Enrico; Ahmed, Ikhlas M. M.; Oliveri, Valentina; Bellia, Francesco; Vileno, Bertrand; El Khoury, Youssef; Hellwig, Petra; Faller, Peter; Vecchio, Graziella
Pubblicato in: https://hal.archives-ouvertes.fr/hal-03079875, Numero 8, 2020, ISSN 0947-6539
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201904885

Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivatives

Autori: Wind, M., Gogolou, A., Manipur, I., Granata, I., Butler, L., Andrews, P.W., Barbaric, I., Ning, K., Guarracino, M.R., Placzek, M., Tsakiridis, A.
Pubblicato in: Development, 2021, ISSN 0950-1991
Editore: The Company of Biologists Ltd.
DOI: 10.1242/dev.194415

The Lipid Chaperon Hypothesis A Common Molecular Mechanism of Membrane Disruption by Intrinsically Disordered Proteins

Autori: M.F.M. Sciacca, F. Lolicato, C. Tempra, F. Scollo, B.R. Sahoo, M.D. Watson, S. García-Viñuales, D. Milardi, A. Raudino, J.C. Lee, A. Ramamoorthy, C. La Rosa
Pubblicato in: ACS Chemical Neuroscience, 2020, ISSN 1948-7193
Editore: American Chemical Society
DOI: 10.1021/acschemneuro.0c00588

Modulation of Endocannabinoid Tone in Osteoblastic Differentiation of MC3T3-E1 Cells and in Mouse Bone Tissue over Time

Autori: Kostrzewa M, Mahmoud AM, Verde R, Scotto di Carlo F, Gianfrancesco F, Piscitelli F, Ligresti A.
Pubblicato in: Cells, 2021, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells10051199

The Ionophoric Activity of a Pro-Apoptotic VEGF 165 Fragment on HUVEC Cells

Autori: S. Zimbone, A.M. Santoro, D. La Mendola, C. Giacomelli, M.L. Trincavelli, M.F. Tomasello, D. Milardi, S. García-Viñuales, M.F. M. Sciacca, C. Martini, G. Grasso
Pubblicato in: International Journal of Molecular Sciences, 2020, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21082866

Epstein–Barr Virus-Associated Malignancies: Roles of Viral Oncoproteins in Carcinogenesis

Autori: El-Sharkawy A, Al Zaidan L and Malki A
Pubblicato in: Frontiers in Oncology, Numero 8:265, 2018, ISSN 2234-943X
Editore: Frontiers Media S. A.
DOI: 10.3389/fonc.2018.00265

From trash to treasure: Detecting unexpected contamination in unmapped NGS data

Autori: Sangiovanni, M., Granata, I., Thind, A.S., Guarracino, M.R
Pubblicato in: BMC Bioinformatics, 2019, ISSN 1471-2458
Editore: BioMed Central
DOI: 10.1186/s12859-019-2684-x

Hyaluronan-carnosine conjugates inhibit Aβ aggregation and toxicity

Autori: V. Greco; I. Naletova; I.M.M. Ahmed; S. Vaccaro; L. Messina; D. La Mendola; F. Bellia; S. Sciuto; C. Satriano; E. Rizzarelli
Pubblicato in: Sci. Rep, Numero 10, 2020, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-020-72989-2

Topographical and Biomechanical Guidance of Electrospun Fibers for Biomedical Application

Autori: Ferraris S., Spriano S., Calogero Scalia A., Cochis A., Rimondini L., Cruz-Maya I., Guarino V., Varesano A, and Vineis C.
Pubblicato in: Polymers, 2020, ISSN 2073-4360
Editore: MDPI
DOI: 10.3390/polym12122896

Macro-, micro- and mesoporous materials for tissue engineering applications.

Autori: Chanes-Cuevas O., Perez-Soria A., Cruz-Maya I, Guarino V, Alvarez-Perez MA
Pubblicato in: AIMS Mater Scie, 2018, Pagina/e 1124-1140, ISSN 2372-0484
Editore: AIMS
DOI: 10.3934/matersci.2018.6.1124

Comparative Study of Protein-Rich Electrospun Fibers for In vitro Applications

Autori: Cruz-Maya I., Varesano A., Vineis C., Guarino V
Pubblicato in: Polymers (Basel), Numero 12(8), 2020, ISSN 2073-4360
Editore: MDPI
DOI: 10.3390/polym12081671

Zfp57 inactivation illustrates the role of ICR methylation in imprinted gene expression during neural differentiation of mouse ESCs

Autori: Acurzio B, Verma A, Polito A, Giaccari C, Cecere F, Fioriniello S, Della Ragione F, Fico A, Cerrato F, Angelini C, Feil R, Riccio A.
Pubblicato in: Scientific Reports, 2021, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-021-93297-3

Structure-Activity Relationships of Thiazole and Benzothiazole Derivatives as Selective Cannabinoid CB2 Agonists with in Vivo Anti-Inflammatory Properties

Autori: Ghonim, Aya E., Alessia Ligresti, Alessandro Rabbito, Ali Mokhtar Mahmoud, Vincenzo Di Marzo, Noha A. Osman, Ashraf H. Abadi
Pubblicato in: European Journal of Medicinal Chemistry, 2019, ISSN 0223-5234
Editore: Elsevier BV
DOI: 10.1016/j.ejmech.2019.07.002

Electrospun polycaprolactone nanofibers decorated by drug loaded chitosan nano-reservoirs for antibacterial treatments

Autori: Guarino V., Cruz-Maya I., Altobelli R., Abdul Khodir WK., Ambrosio L., Alvarez-Pérez MA., Almaguer-Flores A.
Pubblicato in: Nanotechnology, 2017, ISSN 0957-4484
Editore: Institute of Physics Publishing
DOI: 10.1088/1361-6528/aa9542

Loss-of-function maternal-effect mutations of PADI6 are associated with familial and sporadic Beckwith-Wiedemann syndrome with multi-locus imprinting disturbance

Autori: Cubellis MV, Pignata L, Verma A, Sparago A, Del Prete R, Monticelli M, Calzari L, Antona V, Melis D, Tenconi R, Russo S, Cerrato F, Riccio A
Pubblicato in: Clinical Epigenetics, Numero 139 (2020), 2020, ISSN 1868-7083
Editore: Springer
DOI: 10.1186/s13148-020-00925-2

IDE Degrades Nociceptin/Orphanin FQ through an Insulin Regulated Mechanism

Autori: G.A. Zingale, F. Bellia, I.M.M. Ahmed, P. Mielczarek , J. Silberring, G. Grasso.
Pubblicato in: J Mol Sci., 2020, ISSN 0947-6539
Editore: John Wiley & Sons Ltd.
DOI: 10.3390/ijms20184447

GlucoCEST MRI for the Evaluation Response to Chemotherapeutic and Metabolic Treatments in a Murine Triple-Negative Breast Cancer: A Comparison with[ 18 F]F-FDG-PET

Autori: Martina Capozza, Annasofia Anemone, Chetan Dhakan, Melania Della Peruta, Martina Bracesco, Sara Zullino, Daisy Villano, Enzo Terreno, Dario Livio Longo, Silvio Aime
Pubblicato in: Molecular Imaging and Biology, 2022, ISSN 1536-1632
Editore: Elsevier BV
DOI: 10.1007/s11307-021-01637-6

HAND2-AS1 is an important long non-coding RNA with a tumor suppressive role in High Grade Serous Carcinoma

Autori: Priyanka Gokulnath, Tiziana de Cristofaro, Ichcha Manipur, Mario Guarracino, Mariastella Zannini.
Pubblicato in: International Journal of Molecular Sciences, 2020, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21114059

Self-associating cellulose-graft-poly(ε-caprolactone) to design nanoparticles for drug release

Autori: Simona Zuppolini; Iriczalli Cruz Maya; Laura Diodato; Vincenzo Guarino; Anna Borriello; Luigi Ambrosio
Pubblicato in: Mat Scie Eng C, Numero 6, 2020, ISSN 0928-4931
Editore: Elsevier BV
DOI: 10.1016/j.msec.2019.110385

Recent Advances in Nuclear Imaging of Receptor Expression to Guide Targeted Therapies in Breast Cancer

Autori: Salvatore B, Caprio MG, Hill BS, Sarnella A, Roviello GN, Zannetti A
Pubblicato in: Cancers (Basel), 2019, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11101614

Tumor-educated mesenchymal stem cells promote pro- metastatic phenotype

Autori: Hill BS, Pelagalli A, Passaro N, Zannetti A.
Pubblicato in: Oncotarget, 2017, ISSN 1949-2553
Editore: Impact Journals
DOI: 10.18632/oncotarget.20265

Recruitment of stromal cells into tumour microenvironment promote the metastatic spread of breast cancer

Autori: Hill BS, Sarnella A, D’Avino G, Zannetti A
Pubblicato in: Semin Cancer Biol ., 2019, ISSN 1044-579X
Editore: Academic Press
DOI: 10.1016/j.semcancer.2019.07.028

Ubiquitin binds the amyloid β peptide and interferes with its clearance pathways

Autori: F.Bellia, V. Lanza, S. Garcia-Vinuales, I.M.M. Ahmed, A. Pietropaolo, C. Iacobucci, G. Malgieri , G. D'Abrosca, R. Fattorusso, V.G. Nicoletti, D. Sbardella, G.R. Tundo, M. Coletta, L. Pirone, E. Pedone, D. Calcagno, G. Grasso, D. Milardi
Pubblicato in: Chemical Science, Numero 9, 2019, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/c8sc03394c

Identification of non-specific Lipid Transfer Protein gene family members in Solanum lycopersicum and insights into the features of Sola l 3 protein

Autori: Nunzio D’Agostino, Martina Buonanno, Joëlle Ayoub, Amalia Barone, Simona Maria Monti & Maria Manuela Rigano
Pubblicato in: Scientific Reports, 2019, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-018-38301-z

Synthesis and molecular targets of N-13-hydroxy-octadienoyl-ethanolamine, a novel endogenous bioactive 15-lipoxygenase-derived metabolite of N-linoleoyl-ethanolamine found in the skin and saliva

Autori: Tinto F, Archambault AS, Dumais É, Rakotoarivelo V, Kostrzewa M, Martin C, Plante PL, Desjardins Y, Simard M, Pouliot R, De Petrocellis L, Ligresti A, Di Marzo V, Flamand N.
Pubblicato in: Biochim Biophys Acta Mol Cell Biol Lipids, 2021, ISSN 1388-1981
Editore: Elsevier BV
DOI: 10.1016/j.bbalip.2021.158954

RankerGUI: A computational framework to compare differential gene expression profiles using rank based statistics

Autori: Thind, A.S., Tripathi, K.P., Guarracino, M.R
Pubblicato in: International Journal of Molecular Sciences, Numero 20, 2019, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20236098

Substitution of the native Zn(II) with Cd(II), Co(II) and Ni(II) changes the downhill unfolding mechanism of Ros 87 to a completely different scenario

Autori: R. Grazioso, S. García-Viñuales, L. Russo, G. D'Abrosca, S. Esposito, L. Zaccaro, R. Iacovino, D. Milardi, R. Fattorusso, G. Malgieri, C. Isernia
Pubblicato in: International Journal of Molecular Sciences, Numero 21, 2020, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21218285

Discovery of Novel Benzofuran-Based Compounds with Neuroprotective and Immunomodulatory Properties for Alzheimer’s Disease Treatment

Autori: Montanari Serena, Ali Mokhtar Mahmoud, Letizia Pruccoli, Alessandro Rabbito, Marina Naldi, Sabrina Petralla, Ignacio Moraleda, et al.
Pubblicato in: European Journal of Medicinal Chemistry, 2019, ISSN 0223-5234
Editore: Elsevier BV
DOI: 10.1016/j.ejmech.2019.05.080

Trehalose Conjugates of Silybin as Prodrugs for Targeting Toxic Aβ Aggregates.

Autori: Sara García-Viñuales; Rashik Ahmed; Michele Sciacca; Valeria Lanza; Maria Laura Giuffrida; Stefania Zimbone; Valeria Romanucci; Armando Zarrelli; Corrado Bongiorno; Natalia Spinella; Clelia Galati; Giovanni Di Fabio; Giuseppe Melacini; Danilo Milardi
Pubblicato in: ACS Chemical Neurosciences, Numero 1, 2020, ISSN 1948-7193
Editore: American Chemical Society
DOI: 10.1021/acschemneuro.0c00232

Benchmark and Parameter Sensitivity Analysis of Single-Cell RNA Sequencing Clustering Methods.

Autori: Monika Krzak; Yordan P. Raykov; Alexios Boukouvalas; Luisa Cutillo; Claudia Angelini
Pubblicato in: Frontiers in Genetics, Numero 5, 2019, ISSN 1664-8021
Editore: Frontiers Media
DOI: 10.3389/fgene.2019.01253

Vitamin D Signaling in Inflammation and Cancer: Molecular Mechanisms and Therapeutic Implications

Autori: El-Sharkawy A., Maliki A.
Pubblicato in: Molecules, Numero 25(14), 2020, ISSN 1420-3049
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules25143219

Silybins inhibit human IAPP amyloid growth and toxicity through stereospecific interactions

Autori: S. García-Viñuales, I. M. Ilie, A. M. Santoro, V. Romanucci, A. Zarrelli, Giovanni Di Fabio, A. Caflisch, D. Milardi
Pubblicato in: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2022, ISSN 1570-9639
Editore: Elsevier BV
DOI: 10.1016/j.bbapap.2022.140772

Therapeutic Potential of a Novel αvβ3 Antagonist to Hamper the Aggressiveness of Mesenchymal Triple Negative Breast Cancer Sub-Type

Autori: Hill BS, Sarnella A, Capasso D, Comegna D, Del Gatto A, Gramanzini M, Albanese S, Saviano M, Zaccaro L, Zannetti A
Pubblicato in: Cancers (Basel), 2019, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11020139

A KHDC3L mutation resulting in recurrent hydatidiform mole causes genome-wide DNA methylation loss in oocytes and persistent imprinting defects post-fertilisation

Autori: Demond H, Anvar Z*, Jahromi BN, Sparago A, Verma A, Davari M, Calzari L, Russo S, Jahromi MA, Monk D, Andrews S, Riccio A*, Kelsey G*
Pubblicato in: Genome Medicine, 2019, ISSN 1756-994X
Editore: BioMed Central
DOI: 10.1186/s13073-019-0694-y

Optimization of Polydopamine coatings onto Poly- ε-caprolactone electrospun fibres for the fabrication of bio-electroconductive interfaces.

Autori: ZuppoliniI S., Cruz Maya I., Guarino V., Borriello A.
Pubblicato in: J Funct Biomater, 2020, ISSN 2079-4983
Editore: MDPI
DOI: 10.3390/jfb11010019

Exploring the Effectiveness of Novel Benzimidazoles as CB2 Ligands: Synthesis, Biological Evaluation, Molecular Docking Studies and ADMET Prediction

Autori: Tonelli Michele, Elena Cichero, Alì Mokhtar Mahmoud, Alessandro Rabbito, Bruno Tasso, Paola Fossa, Alessia Ligresti
Pubblicato in: MedChemComm, 2018, ISSN 2040-2503
Editore: Royal Society of Chemistry
DOI: 10.1039/c8md00461g

Ion mobility spectrometry combined with multivariate statistical analysis: revealing the effects of a drug candidate for Alzheimer’s disease on Aβ1-40 peptide early assembly

Autori: LAZZARO S, OGRINC POTOČNIK N, LAMONT L, VECCHIO G, PAPPALARDO G, HEEREN R.M.A
Pubblicato in: ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2019, ISSN 1618-2650
Editore: Springer
DOI: 10.1007/s00216-019-02030-7

Nutritional Factors, DNA Methylation, and Risk of Type 2 Diabetes and Obesity: Perspectives and Challenges.

Autori: Parrillo, Luca; Spinelli, Rosa; Nicolò, Antonella; Longo, Michele; Mirra, Paola; Raciti, Gregory Alexander; Miele, Claudia; Beguinot, Francesco
Pubblicato in: International Journal of Molecular Sciences, Numero 2, 2019, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20122983

The change of conditions does not affect Ros87 downhill folding mechanism

Autori: R. Grazioso, S. García-Viñuales, G. D’Abrosca, I. Baglivo, P. V. Pedone, D. Milardi, R. Fattorusso, C. Isernia, L. Russo, G. Malgieri
Pubblicato in: Scientific Reports, Numero 10, 2020, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-020-78008-8

In vivo Regeneration of Mineralized Bone Tissue in Anisotropic Biomimetic Sponges.

Autori: Janeth Serrano-Bello; Iriczalli Cruz-Maya; Iriczalli Cruz-Maya; Fernando Suaste-Olmos; Patricia González-Alva; Rosaria Altobelli; Luigi Ambrosio; Luis Alberto Medina; Luis Alberto Medina; Vincenzo Guarino; Marco Antonio Alvarez-Perez
Pubblicato in: Frontiers in Bioengineering and Biotechnology, Vol 8 (2020), Numero 16, 2020, ISSN 1097-0290
Editore: Frontiers Media
DOI: 10.3389/fbioe.2020.00587

A New Bioassay Platform Design for the Discovery of Small Molecules with Anticancer Immunotherapeutic Activity

Autori: Gallo, C., Barra, G., Saponaro, M., Manzo, E., Fioretto, L., Ziaco, M., … Fontana, A.
Pubblicato in: Marine Drugs, Numero 18(12) 604, 2020, Pagina/e 1-14, ISSN 1660-3397
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/md18120604

Non-invasive Investigation of Tumor Metabolism and Acidosis by MRI-CEST Imaging

Autori: Consolino L, Anemone A, Capozza M, Carella A, Irrera P, Corrado A, Dhakan C, Bracesco M, Longo DL.
Pubblicato in: Frontiers in Oncology, 2020, Pagina/e 161, ISSN 2234-943X
Editore: Frontiers Media S. A.
DOI: 10.3389/fonc.2020.00161

Endogenous and artificial miRNAs explore a rich variety of conformations: a potential relationship between secondary structure and biological functionality

Autori: C. M. A. Gangemi, S. Alaimo, A. Pulvirenti, S. Garcia-Viñuales, D. Milardi, A. P. Falanga,d M. E. Fragalà, G. Oliviero, G. Piccialli, N. Borbone, A. Ferro, A. D’Urso, C.M. Croce, R. Purrello
Pubblicato in: Scientific Reports, 2020, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-019-57289-8

Palmitoylethanolamide Counteracts Substance P-Induced Mast Cell Activation in Vitro by Stimulating Diacylglycerol Lipase Activity

Autori: Petrosino Stefania, Aniello Schiano Moriello, Roberta Verde, Marco Allarà, Roberta Imperatore, Alessia Ligresti, Ali Mokhtar Mahmoud, Alessio Filippo Peritore, Fabio Arturo Iannotti, Vincenzo Di Marzo.
Pubblicato in: Journal of Neuroinflammation, 2019, ISSN 1742-2094
Editore: BioMed Central
DOI: 10.1186/s12974-019-1671-5

Clustering analysis of tumor metabolic networks

Autori: Ichcha Manipur, Ilaria Granata, Lucia Maddalena, Mario R. Guarracino
Pubblicato in: BMC Bioinformatics volume, 2020, ISSN 1471-2105
Editore: BioMed Central
DOI: 10.1186/s12859-020-03564-9

Synthesis of the Major Mammalian Metabolites of THCV

Autori: Tinto F, Villano R, Kostrzewa M, Ligresti A, Straker H, Manzo E.
Pubblicato in: J Nat Prod, 2020, ISSN 0163-3864
Editore: American Chemical Society
DOI: 10.1021/acs.jnatprod.9b00831

Adipose Tissue Dysfunction as Determinant of Obesity-Associated Metabolic Complications

Autori: Longo, Michele; Zatterale, Federica; Naderi, Jamal; Parrillo, Luca; Formisano, Pietro; Raciti, Gregory Alexander; Beguinot, Francesco; Miele, Claudia
Pubblicato in: International Journal of Molecular Sciences, Numero 1, 2019, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20092358

Clustering analysis of tumor metabolic networks

Autori: Manipur, I., Granata, I., Maddalena, L., Guarracino, M.R.
Pubblicato in: Bioinformatics, 2020, ISSN 1471-2105
Editore: BioMed Central
DOI: 10.1186/s12859-020-03840-8

Pyrazolones activate proteasome by gating mechanisms and protect neuronal cells from Aβ amyloid toxicity

Autori: M. Santoro, V.Lanza, F. Bellia, D. Sbardella, G. R. Tundo, A. Cannizzo, G. Grasso, M. Arizzi, V. G. Nicoletti, S. Alcaro, G. Costa, A. Pietropaolo; G. Malgieri, G. D'Abrosca, R. Fattorusso, S. García-Viñuales, I. M. M. Ahmed, M. Coletta; D. Milardi
Pubblicato in: ChemMedChem, 2019, Pagina/e 302-316, ISSN 1860-7187
Editore: Wiley-VCH GmbH
DOI: 10.1002/cmdc.201900612

Human Trisomic iPSCs from Down Syndrome Fibroblasts Manifest Mitochondrial Alterations Early during Neuronal Differentiation

Autori: Mollo N, Esposito M, Aurilia M, Scognamiglio R, Accarino R, Bonfiglio F, Cicatiello R, Charalambous M, Procaccini C, Micillo T, Genesio R, Calì G, Secondo A, Paladino S, Matarese G, De Vita G, Conti A, Nitsch L, Izzo
Pubblicato in: Biology (Basel), 2021, ISSN 2079-7737
Editore: MDPI
DOI: 10.3390/biology10070609

Protein based devices for oral tissue repair and regeneration

Autori: Cruz-Maya I., Guarino V., Álvarez-Pérez MA.
Pubblicato in: AIMS Mater Scie, 2018, Pagina/e 156-170, ISSN 2372-0484
Editore: AIMS Press
DOI: 10.3934/matersci.2018.2.156

Site directed mutagenesis of insulin-degrading enzyme allows to single out the molecular basis of peptidase versus E1-like activity: the role of metal ions

Autori: F. Bellia, V. Lanza, I. Ahmed, S. García-Viñuales; E. Veiss, M. Arizzi, D. Calcagno, D. Milardi; G. Grasso
Pubblicato in: Metallomics, 2019, Pagina/e 278-281, ISSN 1756-5901
Editore: Royal Society of Chemistry
DOI: 10.1039/c8mt00288f

Biosynthesis of the Novel Endogenous 15-Lipoxygenase Metabolites N-13-Hydroxy-octodecadienoyl-ethanolamine and 13-Hydroxy-octodecadienoyl-glycerol by Human Neutrophils and Eosinophils

Autori: Archambault AS, Tinto F, Dumais É, Rakotoarivelo V, Kostrzewa M, Plante PL, Martin C, Simard M, Silvestri C, Pouliot R, Laviolette M, Boulet LP, Vitale RM, Ligresti A, Di Marzo V, Flamand N.
Pubblicato in: Cells, 2021, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells10092322

PAX8 expression in high-grade serous ovarian cancer positively regulates attachment to ECM via Integrin β3

Autori: Amata Amy Soriano; Tiziana de Cristofaro; Tina Di Palma; Priyanka Gokulnath; Antonella Izzo; Gaetano Calì; Mariastella Zannini
Pubblicato in: Cancer Cell International, 2019, ISSN 1475-2867
Editore: BioMed Central
DOI: 10.1186/s12935-019-1022-8

Modeling Acquired Resistance to the Second-Generation Androgen Receptor Antagonist Enzalutamide in the TRAMP Model of Prostate Cancer.

Autori: Cerasuolo, Marianna, Federica Maccarinelli, Daniela Coltrini, Ali Mokhtar Mahmoud, Viviana Marolda, Gaia Cristina Ghedini, Sara Rezzola, et al.
Pubblicato in: Cancer research, 2020, Pagina/e 1564-1577, ISSN 0008-5472
Editore: American Association for Cancer Research
DOI: 10.1158/0008-5472.can-18-3637

Polycyclic Maleimide-Based Scaffold as New Privileged Structure for Navigating the Cannabinoid System Opportunities

Autori: Bisi Alessandra, Alì Mokhtar Mahmoud, Marco Allará, Marina Naldi, Federica Belluti, Silvia Gobbi, Alessia Ligresti, Angela Rampa
Pubblicato in: ACS Medicinal Chemistry Letters, 2019, ISSN 1948-5875
Editore: American Chemical Society
DOI: 10.1021/acsmedchemlett.8b00594

Chronic Adipose Tissue Inflammation Linking Obesity to Insulin Resistance and Type 2 Diabetes.

Autori: Federica Zatterale; Federica Zatterale; Michele Longo; Michele Longo; Jamal Naderi; Jamal Naderi; Gregory Alexander Raciti; Gregory Alexander Raciti; Antonella Desiderio; Antonella Desiderio; Claudia Miele; Claudia Miele; Francesco Beguinot; Francesco Beguinot
Pubblicato in: Frontiers in Physiology, Numero 4, 2020, ISSN 0022-3751
Editore: Blackwell Publishing Inc.
DOI: 10.3389/fphys.2019.01607

Correction to: Clustering analysis of tumor metabolic networks

Autori: Manipur, I., Granata, I., Maddalena, L., Guarracino, M.R.
Pubblicato in: BMC Bioinformatics, 2020, ISSN 1545-5963
Editore: IEEE Computer Society
DOI: 10.1109/tcbb.2021.3078089

What's Genetic Variation Got to Do with It? Starvation-Induced Self-Fertilization Enhances Survival in Paramecium

Autori: Thind, A.S., Vitali, V., Guarracino, M.R., Catania, F.
Pubblicato in: Genome Biology and Evolution, Numero 5, 2020, Pagina/e 626-638, ISSN 1759-6653
Editore: Oxford University Press
DOI: 10.1093/gbe/evaa052

Targeted imaging and inhibition of triple-negative breast cancer metastases by a PDGFRβ aptamer

Autori: Camorani S, Hill BS, Collina F, Gargiulo S, Napolitano M, Cantile M, Di Bonito M, Botti G, Fedele M, Zannetti A, Cerchia L.
Pubblicato in: Theranostics, 2018, ISSN 1838-7640
Editore: Ivyspring International Publisher
DOI: 10.7150/thno.27798

New Coumarin Derivatives as Cholinergic and Cannabinoid System Modulators.

Autori: Montanari S, Allarà M, Scalvini L, Kostrzewa M, Belluti F, Gobbi S, Naldi M, Rivara S, Bartolini M, Ligresti A, Bisi A, Rampa A.
Pubblicato in: Molecules, 2021, ISSN 1420-3049
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules26113254

Inhibition of Bone Marrow-Derived Mesenchymal Stem Cells Homing Towards Triple-Negative Breast Cancer Microenvironment Using an Anti-PDGFRβ Aptamer

Autori: Camorani S, Hill BS, Fontanella R, Greco A, Gramanzini M, Auletta L, Gargiulo S, Albanese S, Lucarelli E, Cerchia L, Zannetti A.
Pubblicato in: Theranostics, 2017, ISSN 1838-7640
Editore: Ivyspring International Publisher
DOI: 10.7150/thno.18974

Glioma grade classification via omics imaging

Autori: Maddalena, L., Granata, I., Manipur, I., Manzo, M., Guarracino, M.R.
Pubblicato in: BIOSTEC, 2020, ISSN 1865-0929
Editore: Springer Verlag
DOI: 10.1007/978-3-030-58657-7_31

Netpro2vec: a Graph Embedding Framework for Biomedical Applications

Autori: Manipur, I., Manzo, M., Granata, I., Giordano, M., Maddalena, L., Guarracino, M.R.
Pubblicato in: IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2021, ISSN 1865-0929
Editore: Springer Science and Business Media
DOI: 10.1007/978-3-030-72379-8_9

PAX8, an emerging player in Ovarian Cancer. Advances in Experimental Medicine and Biology

Autori: Priyanka Gokulnath, Amata Amy Soriano, Tiziana de Cristofaro, Tina Di Palma, Mariastella Zannini.
Pubblicato in: Advances in Experimental Medicine and Biology Bool Series, 2021, ISSN 0065-2598
Editore: Springer Nature
DOI: 10.1007/978-3-030-73359-9_6

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