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CORDIS - Risultati della ricerca dell’UE
CORDIS

Institut Pasteur International Docotal Program

Risultati finali

Submission of EURAXESS link to Project Officer - Call 1

The link to the EURAXESS website where call 1 has been published will be sent to the Project Officer.

Report on dissemination activities - Call 2

The report on dissemination activities will include the following information: - Dates of Call Publication and places where it was published (Supporting documents required). - Flyers, brochures, or other information produced - Presentations conferences and meetings or other events - Published articles in the press - Any other means of advertising the programme

Submission of EURAXESS link to Project Officer - Call 2

The link to the EURAXESS website where call 1 has been published will be sent to the Project Officer.

PhD graduation

A document confirming the graduation of ESRs will be submitted upon successful completion of the PhD programme.

Pubblicazioni

A Single Dose of NILV-Based Vaccine Provides Rapid and Durable Protection against Zika Virus

Autori: Min Wen Ku, François Anna, Philippe Souque, Stéphane Petres, Matthieu Prot, Etienne Simon-Loriere, Pierre Charneau, Maryline Bourgine
Pubblicato in: Molecular Therapy, Numero 28/8, 2020, Pagina/e 1772-1782, ISSN 1525-0016
Editore: Nature Publishing Group
DOI: 10.1016/j.ymthe.2020.05.016

Sex differences in IL-17 contribute to chronicity in male versus female urinary tract infection

Autori: Anna Zychlinsky Scharff, Matthieu Rousseau, Livia Lacerda Mariano, Tracy Canton, Camila Rosat Consiglio, Matthew L. Albert, Magnus Fontes, Darragh Duffy, Molly A. Ingersoll
Pubblicato in: JCI Insight, Numero 4/13, 2019, ISSN 2379-3708
Editore: American Society for clinical investigation (ASCI)
DOI: 10.1172/jci.insight.122998

New virus isolates from Italian hydrothermal environments underscore the biogeographic pattern in archaeal virus communities

Autori: Diana P. Baquero, Patrizia Contursi, Monica Piochi, Simonetta Bartolucci, Ying Liu, Virginija Cvirkaite-Krupovic, David Prangishvili, Mart Krupovic
Pubblicato in: The ISME Journal, Numero 14/7, 2020, Pagina/e 1821-1833, ISSN 1751-7362
Editore: Nature Publishing Group
DOI: 10.1038/s41396-020-0653-z

Streptococcus pneumoniae Infection Promotes Histone H3 Dephosphorylation by Modulating Host PP1 Phosphatase

Autori: Wenyang Dong, Orhan Rasid, Christine Chevalier, Michael Connor, Matthew J.G. Eldridge, Melanie Anne Hamon
Pubblicato in: Cell Reports, Numero 30/12, 2020, Pagina/e 4016-4026.e4, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2020.02.116

Shigella promotes major alteration of gut epithelial physiology and tissue invasion by shutting off host intracellular transport

Autori: Mariana L. Ferrari, Valérie Malardé, Alexandre Grassart, Laura Salavessa, Giulia Nigro, Stéphane Descorps-Declere, John R. Rohde, Pamela Schnupf, Vanessa Masson, Guillaume Arras, Damarys Loew, Philippe J. Sansonetti, Nathalie Sauvonnet
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 116/27, 2019, Pagina/e 13582-13591, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.1902922116

The structures of two archaeal type IV pili illuminate evolutionary relationships

Autori: Fengbin Wang, Diana P. Baquero, Zhangli Su, Leticia C. Beltran, David Prangishvili, Mart Krupovic, Edward H. Egelman
Pubblicato in: Nature Communications, Numero 11/1, 2020, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-020-17268-4

STING Gain-of-Function Disrupts Lymph Node Organogenesis and Innate Lymphoid Cell Development in Mice

Autori: Brock G. Bennion, Carys A. Croft, Teresa L. Ai, Wei Qian, Amber M. Menos, Cathrine A. Miner, Marie-Louis Frémond, Jean-Marc Doisne, Prabhakar S. Andhey, Derek J. Platt, Jennifer K. Bando, Erin R. Wang, Hella Luksch, Thierry J. Molina, Elisha D.O. Roberson, Maxim N. Artyomov, Angela Rösen-Wolff, Marco Colonna, Frédéric Rieux-Laucat, James P. Di Santo, Bénédicte Neven, Jonathan J. Miner
Pubblicato in: Cell Reports, Numero 31/11, 2020, Pagina/e 107771, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2020.107771

Fluid dynamics during bleb formation in migrating cells in vivo

Autori: Mohammad Goudarzi, Aleix Boquet-Pujadas, Jean-Christophe Olivo-Marin, Erez Raz
Pubblicato in: PLOS ONE, Numero 14/2, 2019, Pagina/e e0212699, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0212699

Candida albicans Biofilms Are Generally Devoid of Persister Cells

Autori: Iryna Denega, Christophe d’Enfert, Sophie Bachellier-Bassi
Pubblicato in: Antimicrobial Agents and Chemotherapy, Numero 63/5, 2019, ISSN 0066-4804
Editore: American Society for Microbiology
DOI: 10.1128/aac.01979-18

Platelets expressing IgG receptor FcγRIIA/CD32A determine the severity of experimental anaphylaxis

Autori: Héloïse Beutier, Béatrice Hechler, Ophélie Godon, Yu Wang, Caitlin M. Gillis, Luc de Chaisemartin, Aurélie Gouel-Chéron, Stéphanie Magnenat, Lynn E. Macdonald, Andrew J. Murphy, Sylvie Chollet-Martin, Dan Longrois, Christian Gachet, Pierre Bruhns, Friederike Jönsson
Pubblicato in: Science Immunology, Numero 3/22, 2018, Pagina/e eaan5997, ISSN 2470-9468
Editore: American Association for the Advancement of Science
DOI: 10.1126/sciimmunol.aan5997

Adenomatous Polyposis Coli Modulates Actin and Microtubule Cytoskeleton at the Immunological Synapse to Tune CTL Functions

Autori: Marie Juzans, Céline Cuche, Thierry Rose, Marta Mastrogiovanni, Pascal Bochet, Vincenzo Di Bartolo, Andrés Alcover
Pubblicato in: ImmunoHorizons, Numero 4/6, 2020, Pagina/e 363-381, ISSN 2573-7732
Editore: American Association of Immunologists, Inc.
DOI: 10.4049/immunohorizons.2000044

Escaping the immune system by DNA repair and recombination in African trypanosomes

Autori: Núria Sima, Emilia Jane McLaughlin, Sebastian Hutchinson, Lucy Glover
Pubblicato in: Open Biology, Numero 9/11, 2019, Pagina/e 190182, ISSN 2046-2441
Editore: Royal Society Publishing
DOI: 10.1098/rsob.190182

The RNase J-Based RNA Degradosome Is Compartmentalized in the Gastric Pathogen Helicobacter pylori

Autori: Alejandro Tejada-Arranz, Eloïse Galtier, Lamya El Mortaji, Evelyne Turlin, Dmitry Ershov, Hilde De Reuse
Pubblicato in: mBio, Numero 11/5, 2020, ISSN 2150-7511
Editore: American Society for Microbiology
DOI: 10.1128/mbio.01173-20

Uptake, recognition and responses to peptidoglycan in the mammalian host

Autori: Paulo A D Bastos, Richard Wheeler, Ivo G Boneca
Pubblicato in: FEMS Microbiology Reviews, Numero 45/1, 2020, ISSN 1574-6976
Editore: Oxford University Press
DOI: 10.1093/femsre/fuaa044

Structures of filamentous viruses infecting hyperthermophilic archaea explain DNA stabilization in extreme environments

Autori: Fengbin Wang, Diana P. Baquero, Leticia C. Beltran, Zhangli Su, Tomasz Osinski, Weili Zheng, David Prangishvili, Mart Krupovic, Edward H. Egelman
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 117/33, 2020, Pagina/e 19643-19652, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2011125117

Clarin-1 gene transfer rescues auditory synaptopathy in model of Usher syndrome

Autori: Didier Dulon, Samantha Papal, Pranav Patni, Matteo Cortese, Philippe F.Y. Vincent, Margot Tertrais, Alice Emptoz, Abdelaziz Tlili, Yohan Bouleau, Vincent Michel, Sedigheh Delmaghani, Alain Aghaie, Elise Pepermans, Olinda Alegria-Prevot, Omar Akil, Lawrence Lustig, Paul Avan, Saaid Safieddine, Christine Petit, Aziz El-Amraoui
Pubblicato in: Journal of Clinical Investigation, Numero 128/8, 2018, Pagina/e 3382-3401, ISSN 0021-9738
Editore: American Society for Clinical Investigation
DOI: 10.1172/jci94351

CSB promoter downregulation via histone H3 hypoacetylation is an early determinant of replicative senescence

Autori: Clément Crochemore, Cristina Fernández-Molina, Benjamin Montagne, Audrey Salles, Miria Ricchetti
Pubblicato in: Nature Communications, Numero 10/1, 2019, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-019-13314-y

Expression, Role, and Regulation of Neutrophil Fcγ Receptors

Autori: Yu Wang, Friederike Jönsson
Pubblicato in: Frontiers in Immunology, Numero 10, 2019, ISSN 1664-3224
Editore: Frontiers Media SA
DOI: 10.3389/fimmu.2019.01958

A conserved regulator controls asexual sporulation in the fungal pathogen Candida albicans

Autori: Arturo Hernández-Cervantes, Sadri Znaidi, Lasse van Wijlick, Iryna Denega, Virginia Basso, Jeanne Ropars, Natacha Sertour, Derek Sullivan, Gary Moran, Louise Basmaciyan, Fabienne Bon, Frédéric Dalle, Marie-Elisabeth Bougnoux, Teun Boekhout, Ying Yang, Zongwei Li, Sophie Bachellier-Bassi, Christophe d’Enfert
Pubblicato in: Nature Communications, Numero 11/1, 2020, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-020-20010-9

Diversity of mucoid to non-mucoid switch among carbapenemase-producing Klebsiella pneumoniae

Autori: Adriana Chiarelli, Nicolas Cabanel, Isabelle Rosinski-Chupin, Pengdbamba Dieudonné Zongo, Thierry Naas, Rémy A. Bonnin, Philippe Glaser
Pubblicato in: BMC Microbiology, Numero 20/1, 2020, ISSN 1471-2180
Editore: BioMed Central
DOI: 10.1186/s12866-020-02007-y

Intranasal vaccination with a lentiviral vector protects against SARS-CoV-2 in preclinical animal models

Autori: Min-Wen Ku, Maryline Bourgine, Pierre Authié, Jodie Lopez, Kirill Nemirov, Fanny Moncoq, Amandine Noirat, Benjamin Vesin, Fabien Nevo, Catherine Blanc, Philippe Souque, Houda Tabbal, Emeline Simon, David Hardy, Marine Le Dudal, Françoise Guinet, Laurence Fiette, Hugo Mouquet, François Anna, Annette Martin, Nicolas Escriou, Laleh Majlessi, Pierre Charneau
Pubblicato in: Cell Host & Microbe, Numero 29/2, 2021, Pagina/e 236-249.e6, ISSN 1931-3128
Editore: Cell Press
DOI: 10.1016/j.chom.2020.12.010

Bioimage Analysis and Cell Motility

Autori: Aleix Boquet-Pujadas, Jean-Christophe Olivo-Marin, Nancy Guillén
Pubblicato in: Patterns, Numero 2/1, 2021, Pagina/e 100170, ISSN 2666-3899
Editore: Elsevier
DOI: 10.1016/j.patter.2020.100170

Influenza virus infection induces widespread alterations of host cell splicing

Autori: Usama Ashraf, Clara Benoit-Pilven, Vincent Navratil, Cécile Ligneau, Guillaume Fournier, Sandie Munier, Odile Sismeiro, Jean-Yves Coppée, Vincent Lacroix, Nadia Naffakh
Pubblicato in: NAR Genomics and Bioinformatics, Numero 2/4, 2020, ISSN 2631-9268
Editore: Oxford University Press
DOI: 10.1093/nargab/lqaa095

Structure of a filamentous virus uncovers familial ties within the archaeal virosphere

Autori: Fengbin Wang, Diana P Baquero, Zhangli Su, Tomasz Osinski, David Prangishvili, Edward H Egelman, Mart Krupovic
Pubblicato in: Virus Evolution, Numero 6/1, 2020, ISSN 2057-1577
Editore: Oxford University Press
DOI: 10.1093/ve/veaa023

E-cadherin focuses protrusion formation at the front of migrating cells by impeding actin flow

Autori: Cecilia Grimaldi, Isabel Schumacher, Aleix Boquet-Pujadas, Katsiaryna Tarbashevich, Bart Eduard Vos, Jan Bandemer, Jan Schick, Anne Aalto, Jean-Christophe Olivo-Marin, Timo Betz, Erez Raz
Pubblicato in: Nature Communications, Numero 11/1, 2020, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-020-19114-z

Coordinating Cytoskeleton and Molecular Traffic in T Cell Migration, Activation, and Effector Functions

Autori: Marta Mastrogiovanni, Marie Juzans, Andrés Alcover, Vincenzo Di Bartolo
Pubblicato in: Frontiers in Cell and Developmental Biology, Numero 8, 2020, ISSN 2296-634X
Editore: Frontiers Media S.A.
DOI: 10.3389/fcell.2020.591348

BioFlow: a non-invasive, image-based method to measure speed, pressure and forces inside living cells

Autori: Aleix Boquet-Pujadas, Timothée Lecomte, Maria Manich, Roman Thibeaux, Elisabeth Labruyère, Nancy Guillén, Jean-Christophe Olivo-Marin, Alexandre C. Dufour
Pubblicato in: Scientific Reports, Numero 7/1, 2017, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-017-09240-y

Multiple variational image assimilation for accessible micro-elastography

Autori: Aleix Boquet-Pujadas, Jean-Christophe Olivo-Marin
Pubblicato in: Journal of Physics: Conference Series, Numero 1131, 2018, Pagina/e 012014, ISSN 1742-6588
Editore: Institute of Physics
DOI: 10.1088/1742-6596/1131/1/012014

Functionally distinct resident macrophage subsets differentially shape responses to infection in the bladder

Autori: Livia Lacerda Mariano, Matthieu Rousseau, Hugo Varet, Rachel Legendre, Rebecca Gentek, Javier Saenz Coronilla, Marc Bajenoff, Elisa Gomez Perdiguero, Molly A. Ingersoll
Pubblicato in: Science Advances, Numero 6/48, 2020, Pagina/e eabc5739, ISSN 2375-2548
Editore: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abc5739

CIB2, defective in isolated deafness, is key for auditory hair cell mechanotransduction and survival

Autori: Vincent Michel, Kevin T Booth, Pranav Patni, Matteo Cortese, Hela Azaiez, Amel Bahloul, Kimia Kahrizi, Ménélik Labbé, Alice Emptoz, Andrea Lelli, Julie Dégardin, Typhaine Dupont, Asadollah Aghaie, Danuta Oficjalska‐Pham, Serge Picaud, Hossein Najmabadi, Richard J Smith, Michael R Bowl, Steven DM Brown, Paul Avan, Christine Petit, Aziz El‐Amraoui
Pubblicato in: EMBO Molecular Medicine, Numero 9/12, 2017, Pagina/e 1711-1731, ISSN 1757-4676
Editore: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.201708087

Destabilization of the human RED–SMU1 splicing complex as a basis for host-directed antiinfluenza strategy

Autori: Usama Ashraf, Laura Tengo, Laurent Le Corre, Guillaume Fournier, Patricia Busca, Andrew A. McCarthy, Marie-Anne Rameix-Welti, Christine Gravier-Pelletier, Rob W. H. Ruigrok, Yves Jacob, Pierre-Olivier Vidalain, Nicolas Pietrancosta, Thibaut Crépin, Nadia Naffakh
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 116/22, 2019, Pagina/e 10968-10977, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.1901214116

The transcriptional response of pathogenic Leptospira to peroxide reveals new defenses against infection-related oxidative stress

Autori: Crispin Zavala-Alvarado, Odile Sismeiro, Rachel Legendre, Hugo Varet, Giovanni Bussotti, Jan Bayram, Samuel G. Huete, Guillaume Rey, Jean-Yves Coppée, Mathieu Picardeau, Nadia Benaroudj
Pubblicato in: PLOS Pathogens, Numero 16/10, 2020, Pagina/e e1008904, ISSN 1553-7374
Editore: PLOS
DOI: 10.1371/journal.ppat.1008904

Clarin‐2 is essential for hearing by maintaining stereocilia integrity and function

Autori: Lucy A Dunbar, Pranav Patni, Carlos Aguilar, Philomena Mburu, Laura Corns, Helena RR Wells, Sedigheh Delmaghani, Andrew Parker, Stuart Johnson, Debbie Williams, Christopher T Esapa, Michelle M Simon, Lauren Chessum, Sherylanne Newton, Joanne Dorning, Prashanthini Jeyarajan, Susan Morse, Andrea Lelli, Gemma F Codner, Thibault Peineau, Suhasini R Gopal, Kumar N Alagramam, Ronna Hertzano, Didier Dulo
Pubblicato in: EMBO Molecular Medicine, Numero 11/9, 2019, ISSN 1757-4676
Editore: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.201910288

Chemokine-biased robust self-organizing polarization of migrating cells in vivo

Autori: Adan Olguin-Olguin, Anne Aalto, Benoît Maugis, Aleix Boquet-Pujadas, Dennis Hoffmann, Laura Ermlich, Timo Betz, Nir S. Gov, Michal Reichman-Fried, Erez Raz
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 118/7, 2021, Pagina/e e2018480118, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2018480118

Essential dynamic interdependence of FtsZ and SepF for Z-ring and septum formation in Corynebacterium glutamicum

Autori: Adrià Sogues, Mariano Martinez, Quentin Gaday, Mathilde Ben Assaya, Martin Graña, Alexis Voegele, Michael VanNieuwenhze, Patrick England, Ahmed Haouz, Alexandre Chenal, Sylvain Trépout, Rosario Duran, Anne Marie Wehenkel, Pedro M. Alzari
Pubblicato in: Nature Communications, Numero 11/1, 2020, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-020-15490-8

HP1γ binding pre‐mRNA intronic repeats modulates RNA splicing decisions

Autori: Christophe Rachez, Rachel Legendre, Mickaël Costallat, Hugo Varet, Jia Yi, Etienne Kornobis, Christian Muchardt
Pubblicato in: EMBO reports, 2021, ISSN 1469-221X
Editore: Nature Publishing Group
DOI: 10.15252/embr.202052320

The Single-Step Method of RNA Purification Applied to Leptospira

Autori: Crispin Zavala-Alvarado, Nadia Benaroudj
Pubblicato in: Leptospira spp. - Methods and Protocols, Numero 2134, 2020, Pagina/e 41-51, ISBN 978-1-0716-0458-8
Editore: Springer US
DOI: 10.1007/978-1-0716-0459-5_5

Structure and assembly of archaeal viruses

Autori: Diana P. Baquero, Ying Liu, Fengbin Wang, Edward H. Egelman, David Prangishvili, Mart Krupovic
Pubblicato in: Virus Assembly and Exit Pathways, Numero 108, 2020, Pagina/e 127-164, ISBN 9780128207611
Editore: Elsevier
DOI: 10.1016/bs.aivir.2020.09.004

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