Digital Hybrid Breast PET/MRI for Enhanced Diagnosis of Breast Cancer

Resultado final

Quantative reconstruction environment

Demosntration of the quantative reconstruction environment

Definition of biomarker signatures correlated to PET/MRI imaging

Report on the defintion of biomarker signatures correlated to PETMRI imaging

Definition of different types of immune infiltrates: immunoscore

Report on the defintion of the different types of immune infiltrates

Correlation of histopathological parameters, tumour micro-enviroment and PET/MRI imaging

Report on the correlation histopathologicalparameters tumour microenvironment and PETMRI imaging

Report on maintenance of website, updating with project news, results, success information

Report on maintenance of website updating with project news results success information

Project Website and CI

Creation of project website and corporate design for HYPMED Project

End user workshop

A workshop for end users will be organised

Publicaciones

Evaluation of the PETsys TOFPET2 ASIC in multi-channel coincidence experiments

Autores: Vanessa Nadig, David Schug, Bjoern Weissler, Volkmar Schulz
Publicado en: EJNMMI Physics, Edición 8, 2021, ISSN 2197-7364
Editor: Springer Nature
DOI: 10.1186/s40658-021-00370-x

AI-enhanced simultaneous multiparametric 18F-FDG PET/MRI for accurate breast cancer diagnosis

Autores: V. Romeo, P. Clauser, S. Rasul, P. Kapetas, P. Gibbs, P. A. T. Baltzer, M. Hacker, R. Woitek, T. H. Helbich, K. Pinker
Publicado en: European Journal of Nuclear Medicine and Molecular Imaging, Edición 49, 2021, ISSN 1619-7070
Editor: Springer Verlag
DOI: 10.1007/s00259-021-05492-z

108P Epigenetic regulation of the putative breast cancer metastasis suppressor gene SCN4B

Autores: L. Hilgers, A. Hartmann, P.A. Fasching, S. Villwock, L. Moll, S. Roger, R. Knüchel-Clarke, F. Steib, E.D. Dahl
Publicado en: Annals of Oncology, Edición 32, 2021, ISSN 0923-7534
Editor: Oxford University Press
DOI: 10.1016/j.annonc.2021.03.122

Confounding factors in breast magnetic resonance fingerprinting: B1+, slice profile, and diffusion effects

Autores: Teresa Nolte, Hannah Scholten, Nicolas Gross-Weege, Thomas Amthor, Peter Koken, Mariya Doneva, Volkmar Schulz
Publicado en: Magnetic Resonance in Medicine, Edición Vol. 85 No. 4, 2020, Página(s) 1865-1880, ISSN 1522-2594
Editor: International Society for Magnetic Resonance in Medicine
DOI: 10.1002/mrm.28545

Development of a Non-invasive Assessment of Hypoxia and Neovascularization with Magnetic Resonance Imaging in Benign and Malignant Breast Tumors: Initial Results

Autores: Andreas Stadlbauer, Max Zimmermann, Barbara Bennani-Baiti, Thomas H. Helbich, Pascal Baltzer, Paola Clauser, Panagiotis Kapetas, Zsuzsanna Bago-Horvath, Katja Pinker
Publicado en: Molecular Imaging and Biology, 2018, ISSN 1536-1632
Editor: Elsevier BV
DOI: 10.1007/s11307-018-1298-4

Characterization methods for comprehensive evaluations of shielding materials used in an MRI

Autores: Nicolas Gross-Weege, Thomas Dey, Pierre Gebhardt, David Schug, Bjoern Weissler, Volkmar Schulz
Publicado en: Medical Physics, Edición 45/4, 2018, Página(s) 1415-1424, ISSN 0094-2405
Editor: American Association of Physicists in Medicine
DOI: 10.1002/mp.12762

Multiparametric MRI model with dynamic contrast-enhanced and diffusion-weighted imaging enables breast cancer diagnosis with high accuracy

Autores: Michelle Zhang, Joao V. Horvat, Blanca Bernard-Davila, Maria Adele Marino, Doris Leithner, R. Elena Ochoa-Albiztegui, Thomas H. Helbich, Elizabeth A. Morris, Sunitha Thakur, Katja Pinker
Publicado en: Journal of Magnetic Resonance Imaging, Edición 49/3, 2019, Página(s) 864-874, ISSN 1053-1807
Editor: John Wiley & Sons Inc.
DOI: 10.1002/jmri.26285

Automatic segmentation and classification of breast lesions through identification of informative multiparametric PET/MRI features

Autores: Wolf-Dieter Vogl, Katja Pinker, Thomas H. Helbich, Hubert Bickel, Günther Grabner, Wolfgang Bogner, Stephan Gruber, Zsuzsanna Bago-Horvath, Peter Dubsky, Georg Langs
Publicado en: European Radiology Experimental, Edición 3/1, 2019, ISSN 2509-9280
Editor: Springer Nature
DOI: 10.1186/s41747-019-0096-3

PIK3CA Mutational Status Is Associated with High Glycolytic Activity in ER+/HER2− Early Invasive Breast Cancer: a Molecular Imaging Study Using [18F]FDG PET/CT

Autores: Heinrich Magometschnigg, Katja Pinker, Thomas Helbich, Anita Brandstetter, Margaretha Rudas, Thomas Nakuz, Pascal Baltzer, Wolfgang Wadsak, Marcus Hacker, Michael Weber, Peter Dubsky, Martin Filipits
Publicado en: Molecular Imaging and Biology, Edición 21/5, 2019, Página(s) 991-1002, ISSN 1536-1632
Editor: Elsevier BV
DOI: 10.1007/s11307-018-01308-z

Sequential [ 18 F]FDG-[ 18 F]FMISO PET and Multiparametric MRI at 3T for Insights into Breast Cancer Heterogeneity and Correlation with Patient Outcomes: First Clinical Experience

Autores: Piotr Andrzejewski, Georg Wengert, Thomas H. Helbich, Heinrich Magometschnigg, Dietmar Georg, Marcus Hacker, Pascal Baltzer, Paola Clauser, Panagiotis Kapetas, Petra Georg, Wolfgang Wadsak, Katja Pinker
Publicado en: Contrast Media & Molecular Imaging, Edición 2019, 2019, Página(s) 1-9, ISSN 1555-4309
Editor: John Wiley & Sons Inc.
DOI: 10.1155/2019/1307247

A multiparametric [18F]FDG PET/MRI diagnostic model including imaging biomarkers of the tumor and contralateral healthy breast tissue aids breast cancer diagnosis

Autores: Doris Leithner, Joao V. Horvat, Blanca Bernard-Davila, Thomas H. Helbich, R. Elena Ochoa-Albiztegui, Danny F. Martinez, Michelle Zhang, Sunitha B. Thakur, Georg J. Wengert, Anton Staudenherz, Maxine S. Jochelson, Elizabeth A. Morris, Pascal A. T. Baltzer, Paola Clauser, Panagiotis Kapetas, Katja Pinker
Publicado en: European Journal of Nuclear Medicine and Molecular Imaging, Edición 46/9, 2019, Página(s) 1878-1888, ISSN 1619-7070
Editor: Springer Verlag
DOI: 10.1007/s00259-019-04331-6

Limited role of DWI with apparent diffusion coefficient mapping in breast lesions presenting as non-mass enhancement on dynamic contrast-enhanced MRI

Autores: Daly Avendano, Maria Adele Marino, Doris Leithner, Sunitha Thakur, Blanca Bernard-Davila, Danny F. Martinez, Thomas H. Helbich, Elizabeth A. Morris, Maxine S. Jochelson, Pascal A. T. Baltzer, Paola Clauser, Panagiotis Kapetas, Katja Pinker
Publicado en: Breast Cancer Research, Edición 21/1, 2019, ISSN 1465-542X
Editor: Springer Nature
DOI: 10.1186/s13058-019-1208-y

MR image corrections for PET-induced gradient distortions

Autores: Nicolas Gross-Weege, Teresa Nolte, Volkmar Schulz
Publicado en: Physics in Medicine & Biology, Edición 64/2, 2019, Página(s) 02NT03, ISSN 1361-6560
Editor: IOP Publishing
DOI: 10.1088/1361-6560/aaf97a

Algorithms for joint activity–attenuation estimation from positron emission tomography scatter

Autores: Yannick Berker, Volkmar Schulz, Joel S. Karp
Publicado en: EJNMMI Physics, Edición 6/1, 2019, ISSN 2197-7364
Editor: Springer Open
DOI: 10.1186/s40658-019-0254-y

Spiral blurring correction with water–fat separation for magnetic resonance fingerprinting in the breast

Autores: Teresa Nolte, Nicolas Gross‐Weege, Mariya Doneva, Peter Koken, Aaldert Elevelt, Daniel Truhn, Christiane Kuhl, Volkmar Schulz
Publicado en: Magnetic Resonance in Medicine, Edición 83/4, 2019, Página(s) 1192-1207, ISSN 0740-3194
Editor: John Wiley & Sons Inc.
DOI: 10.1002/mrm.27994

Automated Detection and Segmentation of Nonmass-Enhancing Breast Tumors with Dynamic Contrast-Enhanced Magnetic Resonance Imaging

Autores: Ignacio Alvarez Illan, Javier Ramirez, J. M. Gorriz, Maria Adele Marino, Daly Avendano, Thomas Helbich, Pascal Baltzer, Katja Pinker, Anke Meyer-Baese
Publicado en: Contrast Media & Molecular Imaging, Edición 2018, 2018, Página(s) 1-11, ISSN 1555-4309
Editor: John Wiley & Sons Inc.
DOI: 10.1155/2018/5308517

Crystal Delay and Time Walk Correction Methods for Coincidence Resolving Time Improvements of a Digital-Silicon-Photomultiplier-Based PET/MRI Insert

Autores: David Schug, Bjoern Weissler, Pierre Gebhardt, Volkmar Schulz
Publicado en: IEEE Transactions on Radiation and Plasma Medical Sciences, Edición 1/2, 2017, Página(s) 178-190, ISSN 2469-7311
Editor: IEEE
DOI: 10.1109/TNS.2017.2654920

Intercrystal Scatter Rejection for Pixelated PET Detectors

Autores: Christian Ritzer, Patrick Hallen, David Schug, Volkmar Schulz
Publicado en: IEEE Transactions on Radiation and Plasma Medical Sciences, Edición 1/2, 2017, Página(s) 191-200, ISSN 2469-7311
Editor: IEEE
DOI: 10.1109/TNS.2017.2664921

A Simultaneous Multiparametric 18F-FDG PET/MRI Radiomics Model for the Diagnosis of Triple Negative Breast Cancer

Autores: Valeria Romeo, Panagiotis Kapetas, Paola Clauser, Pascal A. T. Baltzer, Sazan Rasul, Peter Gibbs, Marcus Hacker, Ramona Woitek, Katja Pinker, Thomas H. Helbich
Publicado en: Cancers, Edición 14, 2022, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14163944

Emerging Methods in Radiology

Autores: B. Theek, T. Nolte, D. Pantke, F. Schrank, F. Gremse, V. Schulz, F. Kiessling
Publicado en: Der Radiologe, Edición Vol. 60, 2020, Página(s) 41-53, ISSN 1432-2102
Editor: Springer Medizin Verlag
DOI: 10.1007/s00117-020-00696-0

A dedicated PET insert for a 1.5T MR system for simultaneous breast PET/MRI

Autores: V Schulz, B Weissler, V Nadig, D Schug, P Gebhardt, C Kuhl, D Gareis, M Borgo, D Schaart
Publicado en: Nuklearmedizin, Edición Vol 60 No 2, 2021, Página(s) 134-135, ISSN 2567-6407
Editor: Georg Thieme Verlag KG
DOI: 10.1055/s-0041-1726709

Hybrid total-body pet scanners—current status and future perspectives

Autores: V. Nadig, K. Herrmann, F.M. Mottaghy, V. Schulz
Publicado en: European Journal of Nuclear Medicine and Molecular Imaging, Edición Vol. 49, 2021, Página(s) 445-459, ISSN 1619-7089
Editor: Springer-Verlag GmbH
DOI: 10.1007/s00259-021-05536-4

The HYPMED PET/MRI Insert for Enhanced Diagnosis of Breast Cancer

Autores: S. Naunheim, Y. Kuhl, B. Weissler, D. Schug, H. Radermacher, F. Müller, V. Nadig, L. Yin, K. Krueger, P. Gebhardt, N. Gross-Weege, T. Nolte, E. Gegenmantel, M. Borgo, D. Gareis, T. Celik, S. Aussenhofer, A. Salomon, R. Bakker, V. Schulz
Publicado en: 2022
Editor: PSMR-TBP 2022 conference

Class II tumor suppressor genes in breast cancer can be classified according to intrinsic molecular subtypes and may be suitable for risk classification of ductal carcinoma in situ (DCIS)

Autores: E. Dahl
Publicado en: Edición not yet published, 2022
Editor: Deutsche Gesellschaft für Pathologie

Identifying novel class II tumor suppressor genes in breast cancer

Autores: N. Ortiz Brüchle, M. Onyuro, V.J. Dreyer, J.D.P. Engels, T. Longerich, T. Lüdde, S.H. Loosen, U. Neumann, L. Hilgers, S. Villwock, R. Knüchel-Clarke, F. Steib, E. Dahl
Publicado en: ViPa2021: Abstractband, 2021, Página(s) 106
Editor: Deutsche Gesellschaft für Pathologie

Reducing Memory Requirements for Gradient Tree Boosting Models in FPGA Implementations for Position Estimation in PET Detectors

Autores: Karl Krueger, Lukas Johanns, Florian Mueller, Yannick Kuhl, Janko Lambertus, David Schug, Volkmar Schulz
Publicado en: 2022
Editor: PSMR-TBP 2022 conference

ptimization of FPGA-based gradient tree boosting models for position estimation in PET detectors

Autores: K. Krueger, F. Mueller, P. Gebhardt, B. Weissler, D. Schug, V. Schulz
Publicado en: 2021
Editor: IEEE NPSS

A High Count-Rate and Depth-of-Interaction Resolving Single-Layered One-Side Readout Pixelated Scintillator Crystal Array for PET Applications

Autores: J. M. C. Brown, S. E. Brunner, D. R. Schaart
Publicado en: IEEE Transactions on Radiation and Plasma Medical Sciences, Edición 4/3, 2020, Página(s) 361-370, ISSN 2469-7311
Editor: IEEE
DOI: 10.1109/trpms.2019.2948106

Investigation of the Power Consumption of the PETsys TOFPET2 ASIC

Autores: Nadig, Vanessa; Weissler, Bjoern; Radermacher, Harald; Schulz, Volkmar; Schug, David
Publicado en: Edición 1, 2019
Editor: http://arxiv.org/abs/1908.05878

(Hybrid) SPECT and PET Technologies

Autores: Teresa Nolte, Nicolas Gross-Weege, Volkmar Schulz
Publicado en: Recent Results in Cancer Research, Edición Vol. 216, 2020, Página(s) 111-133, ISSN 2197-6767
Editor: Springer-Verlag
DOI: 10.1007/978-3-030-42618-7_3

Derechos de propiedad intelectual

HF-Empfangs-Spulenanordnung für kombinierte PET/MRI-Scanner

Número de solicitud/publicación: DE 102017221037.0
Fecha: 2017-11-24

PET-Detektor für einen kombinierten PET/MRI-Scanner

Número de solicitud/publicación: DE 102017221038.9
Fecha: 2017-11-24

Scintillator array for limited light sharing for depth-of-interaction determination

Número de solicitud/publicación: NL 2020607
Fecha: 2018-03-16

PET-Detektor für einen kombinierten PET/MRI-Scanner

Número de solicitud/publicación: DE 102017221038.9
Fecha: 2017-11-24

Scintillator array for limited light sharing for depth-of-interaction determination

Número de solicitud/publicación: NL 2020607
Fecha: 2018-03-16

PET-Detektor für einen kombinierten PET/MRI-Scanner

Número de solicitud/publicación: DE 102017221038.9
Fecha: 2017-11-24

HF-Empfangs-Spulenanordnung für kombinierte PET/MRI-Scanner

Número de solicitud/publicación: DE 102017221037.0
Fecha: 2017-11-24

Scintillator array for limited light sharing for depth-of-interaction determination

Número de solicitud/publicación: NL 2020607
Fecha: 2018-03-16

PET-Detektor für einen kombinierten PET/MRI-Scanner

Número de solicitud/publicación: DE 102017221038.9
Fecha: 2017-11-24

HF-Empfangs-Spulenanordnung für kombinierte PET/MRI-Scanner

Número de solicitud/publicación: DE 102017221037.0
Fecha: 2017-11-24

Scintillator array for limited light sharing for depth-of-interaction determination

Número de solicitud/publicación: NL 2020607
Fecha: 2018-03-16

HF-Empfangs-Spulenanordnung für kombinierte PET/MRI-Scanner

Número de solicitud/publicación: DE 102017221037.0
Fecha: 2017-11-24

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Resultado final

Publicaciones

Derechos de propiedad intelectual

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