Deliverables Documents, reports (4) Definition of biomarker signatures correlated to PET/MRI imaging Report on the defintion of biomarker signatures correlated to PETMRI imaging Definition of different types of immune infiltrates: immunoscore Report on the defintion of the different types of immune infiltrates Correlation of histopathological parameters, tumour micro-enviroment and PET/MRI imaging Report on the correlation histopathologicalparameters tumour microenvironment and PETMRI imaging Report on maintenance of website, updating with project news, results, success information Report on maintenance of website updating with project news results success information Websites, patent fillings, videos etc. (1) Project Website and CI Creation of project website and corporate design for HYPMED Project Publications Peer reviewed articles (22) Evaluation of the PETsys TOFPET2 ASIC in multi-channel coincidence experiments Author(s): Vanessa Nadig, David Schug, Bjoern Weissler, Volkmar Schulz Published in: EJNMMI Physics, Issue 8, 2021, ISSN 2197-7364 Publisher: Springer Nature DOI: 10.1186/s40658-021-00370-x AI-enhanced simultaneous multiparametric 18F-FDG PET/MRI for accurate breast cancer diagnosis Author(s): V. Romeo, P. Clauser, S. Rasul, P. Kapetas, P. Gibbs, P. A. T. Baltzer, M. Hacker, R. Woitek, T. H. Helbich, K. Pinker Published in: European Journal of Nuclear Medicine and Molecular Imaging, Issue 49, 2021, ISSN 1619-7070 Publisher: Springer Verlag DOI: 10.1007/s00259-021-05492-z 108P Epigenetic regulation of the putative breast cancer metastasis suppressor gene SCN4B Author(s): L. Hilgers, A. Hartmann, P.A. Fasching, S. Villwock, L. Moll, S. Roger, R. Knüchel-Clarke, F. Steib, E.D. Dahl Published in: Annals of Oncology, Issue 32, 2021, ISSN 0923-7534 Publisher: Oxford University Press DOI: 10.1016/j.annonc.2021.03.122 Confounding factors in breast magnetic resonance fingerprinting: B1+, slice profile, and diffusion effects Author(s): Teresa Nolte, Hannah Scholten, Nicolas Gross-Weege, Thomas Amthor, Peter Koken, Mariya Doneva, Volkmar Schulz Published in: Magnetic Resonance in Medicine, Issue Vol. 85 No. 4, 2020, Page(s) 1865-1880, ISSN 1522-2594 Publisher: International Society for Magnetic Resonance in Medicine DOI: 10.1002/mrm.28545 Development of a Non-invasive Assessment of Hypoxia and Neovascularization with Magnetic Resonance Imaging in Benign and Malignant Breast Tumors: Initial Results Author(s): Andreas Stadlbauer, Max Zimmermann, Barbara Bennani-Baiti, Thomas H. Helbich, Pascal Baltzer, Paola Clauser, Panagiotis Kapetas, Zsuzsanna Bago-Horvath, Katja Pinker Published in: Molecular Imaging and Biology, 2018, ISSN 1536-1632 Publisher: Elsevier BV DOI: 10.1007/s11307-018-1298-4 Characterization methods for comprehensive evaluations of shielding materials used in an MRI Author(s): Nicolas Gross-Weege, Thomas Dey, Pierre Gebhardt, David Schug, Bjoern Weissler, Volkmar Schulz Published in: Medical Physics, Issue 45/4, 2018, Page(s) 1415-1424, ISSN 0094-2405 Publisher: American Association of Physicists in Medicine DOI: 10.1002/mp.12762 Multiparametric MRI model with dynamic contrast-enhanced and diffusion-weighted imaging enables breast cancer diagnosis with high accuracy Author(s): Michelle Zhang, Joao V. Horvat, Blanca Bernard-Davila, Maria Adele Marino, Doris Leithner, R. Elena Ochoa-Albiztegui, Thomas H. Helbich, Elizabeth A. Morris, Sunitha Thakur, Katja Pinker Published in: Journal of Magnetic Resonance Imaging, Issue 49/3, 2019, Page(s) 864-874, ISSN 1053-1807 Publisher: John Wiley & Sons Inc. DOI: 10.1002/jmri.26285 Automatic segmentation and classification of breast lesions through identification of informative multiparametric PET/MRI features Author(s): Wolf-Dieter Vogl, Katja Pinker, Thomas H. Helbich, Hubert Bickel, Günther Grabner, Wolfgang Bogner, Stephan Gruber, Zsuzsanna Bago-Horvath, Peter Dubsky, Georg Langs Published in: European Radiology Experimental, Issue 3/1, 2019, ISSN 2509-9280 Publisher: Springer Nature DOI: 10.1186/s41747-019-0096-3 PIK3CA Mutational Status Is Associated with High Glycolytic Activity in ER+/HER2− Early Invasive Breast Cancer: a Molecular Imaging Study Using [18F]FDG PET/CT Author(s): Heinrich Magometschnigg, Katja Pinker, Thomas Helbich, Anita Brandstetter, Margaretha Rudas, Thomas Nakuz, Pascal Baltzer, Wolfgang Wadsak, Marcus Hacker, Michael Weber, Peter Dubsky, Martin Filipits Published in: Molecular Imaging and Biology, Issue 21/5, 2019, Page(s) 991-1002, ISSN 1536-1632 Publisher: Elsevier BV DOI: 10.1007/s11307-018-01308-z Sequential [ 18 F]FDG-[ 18 F]FMISO PET and Multiparametric MRI at 3T for Insights into Breast Cancer Heterogeneity and Correlation with Patient Outcomes: First Clinical Experience Author(s): Piotr Andrzejewski, Georg Wengert, Thomas H. Helbich, Heinrich Magometschnigg, Dietmar Georg, Marcus Hacker, Pascal Baltzer, Paola Clauser, Panagiotis Kapetas, Petra Georg, Wolfgang Wadsak, Katja Pinker Published in: Contrast Media & Molecular Imaging, Issue 2019, 2019, Page(s) 1-9, ISSN 1555-4309 Publisher: John Wiley & Sons Inc. DOI: 10.1155/2019/1307247 A multiparametric [18F]FDG PET/MRI diagnostic model including imaging biomarkers of the tumor and contralateral healthy breast tissue aids breast cancer diagnosis Author(s): Doris Leithner, Joao V. Horvat, Blanca Bernard-Davila, Thomas H. Helbich, R. Elena Ochoa-Albiztegui, Danny F. Martinez, Michelle Zhang, Sunitha B. Thakur, Georg J. Wengert, Anton Staudenherz, Maxine S. Jochelson, Elizabeth A. Morris, Pascal A. T. Baltzer, Paola Clauser, Panagiotis Kapetas, Katja Pinker Published in: European Journal of Nuclear Medicine and Molecular Imaging, Issue 46/9, 2019, Page(s) 1878-1888, ISSN 1619-7070 Publisher: Springer Verlag DOI: 10.1007/s00259-019-04331-6 Limited role of DWI with apparent diffusion coefficient mapping in breast lesions presenting as non-mass enhancement on dynamic contrast-enhanced MRI Author(s): Daly Avendano, Maria Adele Marino, Doris Leithner, Sunitha Thakur, Blanca Bernard-Davila, Danny F. Martinez, Thomas H. Helbich, Elizabeth A. Morris, Maxine S. Jochelson, Pascal A. T. Baltzer, Paola Clauser, Panagiotis Kapetas, Katja Pinker Published in: Breast Cancer Research, Issue 21/1, 2019, ISSN 1465-542X Publisher: Springer Nature DOI: 10.1186/s13058-019-1208-y MR image corrections for PET-induced gradient distortions Author(s): Nicolas Gross-Weege, Teresa Nolte, Volkmar Schulz Published in: Physics in Medicine & Biology, Issue 64/2, 2019, Page(s) 02NT03, ISSN 1361-6560 Publisher: IOP Publishing DOI: 10.1088/1361-6560/aaf97a Algorithms for joint activity–attenuation estimation from positron emission tomography scatter Author(s): Yannick Berker, Volkmar Schulz, Joel S. Karp Published in: EJNMMI Physics, Issue 6/1, 2019, ISSN 2197-7364 Publisher: Springer Open DOI: 10.1186/s40658-019-0254-y Spiral blurring correction with water–fat separation for magnetic resonance fingerprinting in the breast Author(s): Teresa Nolte, Nicolas Gross‐Weege, Mariya Doneva, Peter Koken, Aaldert Elevelt, Daniel Truhn, Christiane Kuhl, Volkmar Schulz Published in: Magnetic Resonance in Medicine, Issue 83/4, 2019, Page(s) 1192-1207, ISSN 0740-3194 Publisher: John Wiley & Sons Inc. DOI: 10.1002/mrm.27994 Automated Detection and Segmentation of Nonmass-Enhancing Breast Tumors with Dynamic Contrast-Enhanced Magnetic Resonance Imaging Author(s): Ignacio Alvarez Illan, Javier Ramirez, J. M. Gorriz, Maria Adele Marino, Daly Avendano, Thomas Helbich, Pascal Baltzer, Katja Pinker, Anke Meyer-Baese Published in: Contrast Media & Molecular Imaging, Issue 2018, 2018, Page(s) 1-11, ISSN 1555-4309 Publisher: John Wiley & Sons Inc. DOI: 10.1155/2018/5308517 Crystal Delay and Time Walk Correction Methods for Coincidence Resolving Time Improvements of a Digital-Silicon-Photomultiplier-Based PET/MRI Insert Author(s): David Schug, Bjoern Weissler, Pierre Gebhardt, Volkmar Schulz Published in: IEEE Transactions on Radiation and Plasma Medical Sciences, Issue 1/2, 2017, Page(s) 178-190, ISSN 2469-7311 Publisher: IEEE DOI: 10.1109/TNS.2017.2654920 Intercrystal Scatter Rejection for Pixelated PET Detectors Author(s): Christian Ritzer, Patrick Hallen, David Schug, Volkmar Schulz Published in: IEEE Transactions on Radiation and Plasma Medical Sciences, Issue 1/2, 2017, Page(s) 191-200, ISSN 2469-7311 Publisher: IEEE DOI: 10.1109/TNS.2017.2664921 A Simultaneous Multiparametric 18F-FDG PET/MRI Radiomics Model for the Diagnosis of Triple Negative Breast Cancer Author(s): Valeria Romeo, Panagiotis Kapetas, Paola Clauser, Pascal A. T. Baltzer, Sazan Rasul, Peter Gibbs, Marcus Hacker, Ramona Woitek, Katja Pinker, Thomas H. Helbich Published in: Cancers, Issue 14, 2022, ISSN 2072-6694 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/cancers14163944 Emerging Methods in Radiology Author(s): B. Theek, T. Nolte, D. Pantke, F. Schrank, F. Gremse, V. Schulz, F. Kiessling Published in: Der Radiologe, Issue Vol. 60, 2020, Page(s) 41-53, ISSN 1432-2102 Publisher: Springer Medizin Verlag DOI: 10.1007/s00117-020-00696-0 A dedicated PET insert for a 1.5T MR system for simultaneous breast PET/MRI Author(s): V Schulz, B Weissler, V Nadig, D Schug, P Gebhardt, C Kuhl, D Gareis, M Borgo, D Schaart Published in: Nuklearmedizin, Issue Vol 60 No 2, 2021, Page(s) 134-135, ISSN 2567-6407 Publisher: Georg Thieme Verlag KG DOI: 10.1055/s-0041-1726709 Hybrid total-body pet scanners—current status and future perspectives Author(s): V. Nadig, K. Herrmann, F.M. Mottaghy, V. Schulz Published in: European Journal of Nuclear Medicine and Molecular Imaging, Issue Vol. 49, 2021, Page(s) 445-459, ISSN 1619-7089 Publisher: Springer-Verlag GmbH DOI: 10.1007/s00259-021-05536-4 Conference proceedings (5) The HYPMED PET/MRI Insert for Enhanced Diagnosis of Breast Cancer Author(s): S. Naunheim, Y. Kuhl, B. Weissler, D. Schug, H. Radermacher, F. Müller, V. Nadig, L. Yin, K. Krueger, P. Gebhardt, N. Gross-Weege, T. Nolte, E. Gegenmantel, M. Borgo, D. Gareis, T. Celik, S. Aussenhofer, A. Salomon, R. Bakker, V. Schulz Published in: 2022 Publisher: PSMR-TBP 2022 conference Class II tumor suppressor genes in breast cancer can be classified according to intrinsic molecular subtypes and may be suitable for risk classification of ductal carcinoma in situ (DCIS) Author(s): E. Dahl Published in: Issue not yet published, 2022 Publisher: Deutsche Gesellschaft für Pathologie Identifying novel class II tumor suppressor genes in breast cancer Author(s): N. Ortiz Brüchle, M. Onyuro, V.J. Dreyer, J.D.P. Engels, T. Longerich, T. Lüdde, S.H. Loosen, U. Neumann, L. Hilgers, S. Villwock, R. Knüchel-Clarke, F. Steib, E. Dahl Published in: ViPa2021: Abstractband, 2021, Page(s) 106 Publisher: Deutsche Gesellschaft für Pathologie Reducing Memory Requirements for Gradient Tree Boosting Models in FPGA Implementations for Position Estimation in PET Detectors Author(s): Karl Krueger, Lukas Johanns, Florian Mueller, Yannick Kuhl, Janko Lambertus, David Schug, Volkmar Schulz Published in: 2022 Publisher: PSMR-TBP 2022 conference ptimization of FPGA-based gradient tree boosting models for position estimation in PET detectors Author(s): K. Krueger, F. Mueller, P. Gebhardt, B. Weissler, D. Schug, V. Schulz Published in: 2021 Publisher: IEEE NPSS Non-peer reviewed articles (1) A High Count-Rate and Depth-of-Interaction Resolving Single-Layered One-Side Readout Pixelated Scintillator Crystal Array for PET Applications Author(s): J. M. C. Brown, S. E. Brunner, D. R. Schaart Published in: IEEE Transactions on Radiation and Plasma Medical Sciences, Issue 4/3, 2020, Page(s) 361-370, ISSN 2469-7311 Publisher: IEEE DOI: 10.1109/trpms.2019.2948106 Other (1) Investigation of the Power Consumption of the PETsys TOFPET2 ASIC Author(s): Nadig, Vanessa; Weissler, Bjoern; Radermacher, Harald; Schulz, Volkmar; Schug, David Published in: Issue 1, 2019 Publisher: http://arxiv.org/abs/1908.05878 Monographic books (1) (Hybrid) SPECT and PET Technologies Author(s): Teresa Nolte, Nicolas Gross-Weege, Volkmar Schulz Published in: Recent Results in Cancer Research, Issue Vol. 216, 2020, Page(s) 111-133, ISSN 2197-6767 Publisher: Springer-Verlag DOI: 10.1007/978-3-030-42618-7_3 Intellectual Property Rights Patent (12) HF-Empfangs-Spulenanordnung für kombinierte PET/MRI-Scanner Application/Publication number: DE 102017221037.0 Date: 2017-11-24 PET-Detektor für einen kombinierten PET/MRI-Scanner Application/Publication number: DE 102017221038.9 Date: 2017-11-24 Scintillator array for limited light sharing for depth-of-interaction determination Application/Publication number: NL 2020607 Date: 2018-03-16 PET-Detektor für einen kombinierten PET/MRI-Scanner Application/Publication number: DE 102017221038.9 Date: 2017-11-24 Scintillator array for limited light sharing for depth-of-interaction determination Application/Publication number: NL 2020607 Date: 2018-03-16 PET-Detektor für einen kombinierten PET/MRI-Scanner Application/Publication number: DE 102017221038.9 Date: 2017-11-24 HF-Empfangs-Spulenanordnung für kombinierte PET/MRI-Scanner Application/Publication number: DE 102017221037.0 Date: 2017-11-24 Scintillator array for limited light sharing for depth-of-interaction determination Application/Publication number: NL 2020607 Date: 2018-03-16 PET-Detektor für einen kombinierten PET/MRI-Scanner Application/Publication number: DE 102017221038.9 Date: 2017-11-24 HF-Empfangs-Spulenanordnung für kombinierte PET/MRI-Scanner Application/Publication number: DE 102017221037.0 Date: 2017-11-24 Scintillator array for limited light sharing for depth-of-interaction determination Application/Publication number: NL 2020607 Date: 2018-03-16 HF-Empfangs-Spulenanordnung für kombinierte PET/MRI-Scanner Application/Publication number: DE 102017221037.0 Date: 2017-11-24 Searching for OpenAIRE data... 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