CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.
Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .
Resultado final
This report will demonstrate the degree to which MRF derived biomarkers can predict the development of metastasis in a liver cancer model
Report on results from preclinical trials (se abrirá en una nueva ventana)Results from in vivo tests on orthotopically implanted tumours or experimental metastasis in mice using both research scanner and commercial scanner. The aim is to verify results from the in vitro experiments.
Final report on MRF sequences development and results (se abrirá en una nueva ventana)Final report on clinical study and value of MRF to predict MVI. (se abrirá en una nueva ventana)
This final report after the 6 months of allowing for final data analysis will show the value MRF provides for predicting the presenceabsence of MVI in HCC This report will also refer to the resultsobtained via ScreenCell and establish whether a combination of CTC derived information plus MRF derived biomarkers has the potential to further improve the prediction of MVI
Final report on IFP/active force reconstruction method (se abrirá en una nueva ventana)The Integrity of invasive IFP measurements in vitro active force data from TFM measurements on tumour spheroids and preclinical tumours as well as histopathological results from preclinical and clinical tumour cases allows to optimize and finalize the force reconstruction
Final report on clinical study (se abrirá en una nueva ventana)This final report after the 6 months of allowing for final data analysis will show the value MRF provides for predicting the presenceabsence of lympnode involvement It will further demonstrate the value of IFP quantified via MRF for predicting response to therapy in this cohort of patients Correlation to results obtained via ScreenCell will provide further insight into the question whether CTC data help to increase the ability of MRF derived imaging biomarkers to predict metastatic potential
Final report on clinical study and value of MRF in brain tumour delineation (se abrirá en una nueva ventana)This final report after the 6 months of allowing for final data analysis will show the value that MRF provides for predicting the presenceabsence and delineation of tumour cells in primary brain tumours and metastases This report will also refer to the results obtained by conventional means and histopathological correlations
Final Report on ability of MRF derived IFP for predicting response to therapy in liver cancer models (se abrirá en una nueva ventana)Final report on CTC analysis for HCC (se abrirá en una nueva ventana)
ScreenCell will summarize its findings and show to which degree advanced CTC analysis in combination with MRF derived imaging biomarkers enhance the sensitivity to predict microvascular involvement for HCC It will also summarize how the TFM findings correlate to the histopathological results of the individual tumour specimen
Final report on beast and brain cancer metastasis models (se abrirá en una nueva ventana)This report will demonstrate the degree to which MRF derived biomarkers can predict the development of metastasis in breast and brain cancer model
Report on clinical MRF protocol for breast (se abrirá en una nueva ventana)After 14 month KCL has collected data about the reproducibility, stability, and precision of the current MRF protocol
Final report on TFM results (se abrirá en una nueva ventana)This report will demonstrate the degree to which TFM derived force measurements correlate with MRF derived values. This represents an important step in the validation of MRF for being able to actually measure the active forces of a tumour exerted onto its habitat.
Publicaciones
Autores:
Jin Li, Konstantinos Zormpas-Petridis, Andreas Heindl, Jessica K.R. Boult, Craig Cummings, Jeffrey C. Bamber, Yinyin Yuan, Ralph Sinkus, Yann Jamin, Simon P. Robinson
Publicado en:
Proceedings of the Annual Meeting of the International Society for Magnetic Resonance in Medicine, 2018, Página(s) "Abstr #629"
Editor:
ISMRM
Autores:
Emma Reeves, Jin Li, Konstantinos Zormpas-Petridis, Andreas Heindl, Jessica K.R. Boult, Craig Cummings, Jeffrey C. Bamber, Yinyin Yuan, Ralph Sinkus, Yann Jamin, Simon P. Robinson
Publicado en:
Forces in Cancer: interdisciplinary approaches in tumour mechanobiology, 2018
Editor:
The Royal Society
Autores:
James P. B. O'Connor, Eric O. Aboagye, Judith E. Adams, Hugo J. W. L. Aerts, Sally F. Barrington, Ambros J. Beer, Ronald Boellaard, Sarah E. Bohndiek, Michael Brady, Gina Brown, David L. Buckley, Thomas L. Chenevert, Laurence P. Clarke, Sandra Collette, Gary J. Cook, Nandita M. deSouza, John C. Dickson, Caroline Dive, Jeffrey L. Evelhoch, Corinne Faivre-Finn, Ferdia A. Gallagher, Fiona J. Gilbert,
Publicado en:
Nature Reviews Clinical Oncology, Edición 14/3, 2017, Página(s) 169-186, ISSN 1759-4774
Editor:
Nature Publishing Group
DOI:
10.1038/nrclinonc.2016.162
Autores:
Linda Oswald, Steffen Grosser, David M Smith, Josef A Käs
Publicado en:
Journal of Physics D: Applied Physics, Edición 50/48, 2017, Página(s) 483001, ISSN 0022-3727
Editor:
Institute of Physics Publishing
DOI:
10.1088/1361-6463/aa8e83
Autores:
Claudia Tanja Mierke, Frank Sauer, Steffen Grosser, Stefanie Puder, Tony Fischer, Josef Alfons Käs
Publicado en:
NMR in Biomedicine, Edición 31/10, 2018, Página(s) e3831, ISSN 0952-3480
Editor:
John Wiley & Sons Inc.
DOI:
10.1002/nbm.3831
Autores:
Guenthner, Christian; Runge, Jurgen Henk; Sinkus, Ralph; Kozerke, Sebastian
Publicado en:
Guenthner, Christian; Runge, Jurgen Henk; Sinkus, Ralph; Kozerke, Sebastian (2018). Analysis and improvement of motion encoding in magnetic resonance elastography. NMR in Biomedicine, 31(5):e3908., Edición 1, 2018, ISSN 0952-3480
Editor:
John Wiley & Sons Inc.
DOI:
10.5167/uzh-159366
Autores:
Christian Guenthner, Sebastian Kozerke
Publicado en:
NMR in Biomedicine, Edición 31/10, 2018, Página(s) e3919, ISSN 0952-3480
Editor:
John Wiley & Sons Inc.
DOI:
10.1002/nbm.3919
Autores:
Vikash Pandey and Sverre Holm
Publicado en:
Physical Review E, Edición Vol. 94, Edición 3, 2016, Página(s) 032606, ISSN 2470-0045
Editor:
American Physical Society
DOI:
10.1103/PhysRevE.94.032606
Autores:
Daniel Fovargue, David Nordsletten, Ralph Sinkus
Publicado en:
NMR in Biomedicine, Edición 31/10, 2018, Página(s) e3935, ISSN 0952-3480
Editor:
John Wiley & Sons Inc.
DOI:
10.1002/nbm.3935
Autores:
Jurgen Henk Runge, Stefan Heinz Hoelzl, Jelizaveta Sudakova, Ayse Sila Dokumaci, Jules Laurent Nelissen, Christian Guenthner, Jack Lee, Marian Troelstra, Daniel Fovargue, Jaap Stoker, Aart Johannes Nederveen, David Nordsletten, Ralph Sinkus
Publicado en:
Physics in Medicine & Biology, Edición 64/4, 2019, Página(s) 045007, ISSN 1361-6560
Editor:
IOP Publishing
DOI:
10.1088/1361-6560/aaf9f8
Autores:
Daniel Fovargue, Sebastian Kozerke, Ralph Sinkus, David Nordsletten
Publicado en:
Medical Image Analysis, Edición 44, 2018, Página(s) 126-142, ISSN 1361-8415
Editor:
Elsevier BV
DOI:
10.1016/j.media.2017.12.005
Autores:
Samuel Patz, Daniel Fovargue, Katharina Schregel, Navid Nazari, Miklos Palotai, Paul E. Barbone, Ben Fabry, Alexander Hammers, Sverre Holm, Sebastian Kozerke, David Nordsletten, Ralph Sinkus
Publicado en:
Science Advances, Edición 5/4, 2019, Página(s) eaav3816, ISSN 2375-2548
Editor:
Science Advances
DOI:
10.1126/sciadv.aav3816
Autores:
Stefan Hetzer, Patric Birr, Andreas Fehlner, Sebastian Hirsch, Florian Dittmann, Eric Barnhill, Jürgen Braun, Ingolf Sack
Publicado en:
Journal of Cerebral Blood Flow & Metabolism, 2016, Página(s) 0271678X1769153, ISSN 0271-678X
Editor:
Lippincott Williams & Wilkins Ltd.
DOI:
10.1177/0271678X17691530
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