Advanced BiomEdical OPTICAL Imaging and Data Analysis

Projektinformationen

BE-OPTICAL

ID Finanzhilfevereinbarung: 675512

DOI

10.3030/675512

Projekt abgeschlossen

EK-Unterschriftsdatum 7 August 2015

Startdatum 1 Oktober 2015

Enddatum 30 September 2019

Finanziert unter

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Gesamtkosten

€ 3 495 300,48

EU-Beitrag

€ 3 495 300,48

Koordiniert durch

UNIVERSITAT POLITECNICA DE CATALUNYA
Spain

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

Other (8)

Workshop 4
Final conference
Workshop 3
School 2 + Hands on modules 1+2

School 2 (resp. UGO) + Hands on Training modules 1 + 2 (resp PQInno). The two events will be co-located and integrated as one event.

School 1
Software library for camera control, calibration, 4D reconstruction, motion analysis and artefact removal

Software library for: camera control; calibration; 4D reconstruction; motion analysis; motion artefact removal.

Mid-Term Review Meeting + Workshop 2

Midterm review meeting resp UPC and Workshop 2 organised by USTAN The two events will be colocated and run consecutively

Workshop 1 + Hands on Modules 3+4

Workshop 1 (resp NCU) + Hands on Modules 3+4 (resp. IMO) will be colocated. They will be integrated into one event.

Demonstrators, pilots, prototypes (12)

Prototype of the combined SOFI-Light-Sheet microscope

Prototype of the combined SOFI-Light-Sheet microscope

Prototype and report of a SS-OCT instrument for heart imaging

Prototype and report of an SS-OCT instrument for heart imaging

Prototype of a hyperspectral imaging instrument for the dynamic recording of the ocular fundus

Prototype of a hyperspectral imaging instrument for the dynamic recording of the ocular fundus

Prototype of the endoscopic FRET imaging system
Prototype for Airy beam Light-Sheet microscope

Prototype for an Airy beam Light-Sheet microscope

Prototype of a fluorescence decay based multiplexing system
Demonstration of active spatio-temporal modulation of the phase and amplitude for non-diffractive beam generation
Prototype and report of an OCT system that can be integrated in the instrument for the evaluation of vision in a fully autonomous and automatic way within a clinical environment

Prototype and report of an OCT system that can be integrated in the instrument for the evaluation of vision in a fully autonomous and automatic way within a clinical environment, including control software and user interace.

Prototype of the fibre-optic FRET imaging system
Prototype of the imaging system (optics and electronics)
Prototype and report of a SLO-OCT instrument for opthalmic imaging and its performance for in-vivo imaging

Prototype and report of a SLO-OCT instrument for opthalmic imaging and its performance for in-vivo imaging of the eye

Demonstration of living cell membrane imaging using NS substrates

Documents, reports (17)

Report on the performance of the hyperspectral imaging instrument for the dynamic recording of the ocular fundus
Report on the incoherent emission characteristics of diode light sources under various optical feedback and injection configurations
Report on the performance of the HDA prototype that incorporates the identified incoherent diode-based light source
Report describing the SOFI-Light-Sheet microscope
Report on clinical studies of eyes with ocular diseases
Report describing the Airy beam Light-Sheet microscope
Report on the performance of instrument for the complete evaluation of vision, control software and user interface
Report on novel deconvolution techniques which rectify SOFI brightness skewing by delivering images of linear intensity scaling
Report on the performance of the Airy beam Light-Sheet Microscopy for imaging biological specimens
Report on sample preparation, experimental conditions and data analysis for time-resolved multiplexing in cell microscopy
Report on enhanced light collection of multiphoton confocal function
Report describing the FPGA-based SOFI
Report on the techniques for classification and analysis of 2D images of cardiac and opthalmic images

Report on the performance of novel methods of analysis for classification and analysis of 2D images of cardiac and opthalmic images

Final report
Report on the NS substrate validation with GFP-marked living cells
Report on the performance of the combined SOFI-LSM techniques for imaging life organisms such as nematodes
Report on the performance of the method of reducing refractive index without altering electrical function

Websites, patent fillings, videos etc. (2)

BE-OPTICAL dissemination videos + brochure

BE-OPTICAL dissemination videos + brochure: There will be several of these throughout the project, targetting different sectors and audiences: achivements aimed for the general public; optical imaging achievments aimed at the scientific community; opthalmic achievments (scientfic community)

Patent application

Veröffentlichungen

Peer reviewed articles (14)

Wide-field multiphoton imaging through scattering media without correction

Autoren: Adrià Escobet-Montalbán, Roman Spesyvtsev, Mingzhou Chen, Wardiya Afshar Saber, Melissa Andrews, C. Simon Herrington, Michael Mazilu, Kishan Dholakia
Veröffentlicht in: Science Advances, Ausgabe 4/10, 2018, Seite(n) eaau1338, ISSN 2375-2548
Herausgeber: American Association for the Advancement of Science
DOI: 10.1126/sciadv.aau1338

Energy-Reduced Arrhythmia Termination Using Global Photostimulation in Optogenetic Murine Hearts

Autoren: Raúl A. Quiñonez Uribe, Stefan Luther, Laura Diaz-Maue, Claudia Richter
Veröffentlicht in: Frontiers in Physiology, Ausgabe 9, 2018, Seite(n) 1651, ISSN 1664-042X
Herausgeber: Frontiers Research Foundation
DOI: 10.3389/fphys.2018.01651

Unsupervised feature extraction of anterior chamber OCT images for ordering and classification

Autoren: Pablo Amil, Laura González, Elena Arrondo, Cecilia Salinas, J. L. Guell, Cristina Masoller, Ulrich Parlitz
Veröffentlicht in: Scientific Reports, Ausgabe 9/1, 2019, ISSN 2045-2322
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41598-018-38136-8

Three-photon light-sheet fluorescence microscopy

Autoren: Adrià Escobet-Montalbán, Federico M. Gasparoli, Jonathan Nylk, Pengfei Liu, Zhengyi Yang, and Kishan Dholakia
Veröffentlicht in: Optics Letters, Ausgabe 43/21, 2018, Seite(n) 5484-5487, ISSN 0146-9592
Herausgeber: Optical Society of America
DOI: 10.17630/ff413c1a-3670-427f-9f3f-670518b172b6

Experimental characterization of the speckle pattern at the output of a multimode optical fiber

Autoren: Donatus Halpaap, Jordi Tiana-Alsina, Meritxell Vilaseca, Cristina Masoller
Veröffentlicht in: Optics Express, Ausgabe 27/20, 2019, Seite(n) 27737, ISSN 1094-4087
Herausgeber: Optical Society of America
DOI: 10.1364/oe.27.027737

Fast visible and extended near-infrared multispectral fundus camera

Autoren: Tommaso Alterini; Fernando Díaz-Doutón; Francisco J. Burgos-Fernández; Laura González; Carlos Mateo; Meritxell Vilaseca
Veröffentlicht in: Journal of Biomedical Optics, Ausgabe 24/09, 2019, Seite(n) 1, ISSN 1083-3668
Herausgeber: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.24.9.096007

High-speed OCT-based ocular biometer combined with an air-puff system for determination of induced retraction-free eye dynamics

Autoren: Alfonso Jiménez-villar, Ewa Mączyńska, Artur Cichański, Maciej Wojtkowski, Bartłomiej J. Kałużny, Ireneusz Grulkowski
Veröffentlicht in: Biomedical Optics Express, Ausgabe 10/7, 2019, Seite(n) 3663, ISSN 2156-7085
Herausgeber: The Optical Society
DOI: 10.1364/boe.10.003663

Spatiotemporal optical coherence (STOC) manipulation suppresses coherent cross-talk in full-field swept-source optical coherence tomography

Autoren: Dawid Borycki, Michał Hamkało, Maciej Nowakowski, Maciej Szkulmowski, Maciej Wojtkowski
Veröffentlicht in: Biomedical Optics Express, Ausgabe 10/4, 2019, Seite(n) 2032, ISSN 2156-7085
Herausgeber: The Optical Society
DOI: 10.1364/boe.10.002032

Air-Puff-Induced Dynamics of Ocular Components Measured with Optical Biometry

Autoren: Ewa Maczynska, Jagoda Rzeszewska-Zamiara, Alfonso Jimenez Villar, Maciej Wojtkowski, Bartlomiej J. Kaluzny, Ireneusz Grulkowski
Veröffentlicht in: Investigative Opthalmology & Visual Science, Ausgabe 60/6, 2019, Seite(n) 1979, ISSN 1552-5783
Herausgeber: ARVO Journals
DOI: 10.1167/iovs.19-26681

Speckle reduction in double-pass retinal images

Autoren: Donatus Halpaap, Carlos E. García-Guerra, Meritxell Vilaseca, Cristina Masoller
Veröffentlicht in: Scientific Reports, Ausgabe 9/1, 2019, ISSN 2045-2322
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41598-019-41168-3

Machine learning algorithms for predicting the amplitude of chaotic laser pulses

Autoren: Pablo Amil, Miguel C. Soriano, Cristina Masoller
Veröffentlicht in: Chaos: An Interdisciplinary Journal of Nonlinear Science, Ausgabe 29/11, 2019, Seite(n) 113111, ISSN 1054-1500
Herausgeber: American Institute of Physics
DOI: 10.1063/1.5120755

Optimal compressive multiphoton imaging at depth using single-pixel detection

Autoren: Philip Wijesinghe, Adrià Escobet-Montalbán, Mingzhou Chen, Peter R. T. Munro, Kishan Dholakia
Veröffentlicht in: Optics Letters, Ausgabe 44/20, 2019, Seite(n) 4981, ISSN 0146-9592
Herausgeber: Optical Society of America
DOI: 10.1364/ol.44.004981

Outlier Mining Methods Based on Graph Structure Analysis

Autoren: Pablo Amil, Nahuel Almeira, Cristina Masoller
Veröffentlicht in: Frontiers in Physics, Ausgabe 7, 2019, ISSN 2296-424X
Herausgeber: Frontiers Media S.A
DOI: 10.3389/fphy.2019.00194

Network-based features for retinal fundus vessel structure analysis

Autoren: Pablo Amil, Cesar F. Reyes-Manzano, Lev Guzmán-Vargas, Irene Sendiña-Nadal, Cristina Masoller
Veröffentlicht in: PLOS ONE, Ausgabe 14/7, 2019, Seite(n) e0220132, ISSN 1932-6203
Herausgeber: Public Library of Science
DOI: 10.1371/journal.pone.0220132

Conference proceedings (2)

Hyperspectral fundus camera with sensitivity beyond the visible range: a pilot study

Autoren: Tommaso Alterini; Fernando Díaz-Doutón; Meritxell Vilaseca
Veröffentlicht in: Investigative Ophthalmology & Visual Science, Ausgabe 59, 2018, Seite(n) 5865
Herausgeber: ARVO Journal

Relation between IOP and air-puff-induced dynamics of ocular components in human eyes measured with full-eye-length SS-OCT

Autoren: Ireneusz Grulkowski; Ewa Maczynska; Jagoda Rzeszewska; Alfonso Jimenez-Villar; Maciej Wojtkowski; Bartlomiej Kaluzny
Veröffentlicht in: Investigative Ophthalmology & Visual Science, Ausgabe 59, 2018, Seite(n) 279
Herausgeber: ARVO Journal

Rechte des geistigen Eigentums

Patent (3)

IMAGE PROCESSING METHOD FOR GLAUCOMA DETECTION AND COMPUTER PROGRAM PRODUCTS THEREOF

Antrags-/Publikationsnummer: 20 17057792
Datum: 2017-12-11
Antragsteller: MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV

IMAGE PROCESSING METHOD FOR GLAUCOMA DETECTION AND COMPUTER PROGRAM PRODUCTS THEREOF

Antrags-/Publikationsnummer: 20 17057792
Datum: 2017-12-11
Antragsteller: UNIVERSITAT POLITECNICA DE CATALUNYA

IMAGE PROCESSING METHOD FOR GLAUCOMA DETECTION AND COMPUTER PROGRAM PRODUCTS THEREOF

Antrags-/Publikationsnummer: 20 17057792
Datum: 2017-12-11
Antragsteller: INSTITUTO DE MICROCIRUGIA OCULAR DOS SLP