Advanced BiomEdical OPTICAL Imaging and Data Analysis

Informazioni relative al progetto

BE-OPTICAL

ID dell’accordo di sovvenzione: 675512

DOI

10.3030/675512

Progetto chiuso

Data della firma CE 7 Agosto 2015

Data di avvio 1 Ottobre 2015

Data di completamento 30 Settembre 2019

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale

€ 3 495 300,48

Contributo UE

€ 3 495 300,48

Coordinato da

UNIVERSITAT POLITECNICA DE CATALUNYA
Spain

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Other (8)

Workshop 4
Final conference
Workshop 3
School 2 + Hands on modules 1+2

School 2 (resp. UGO) + Hands on Training modules 1 + 2 (resp PQInno). The two events will be co-located and integrated as one event.

School 1
Software library for camera control, calibration, 4D reconstruction, motion analysis and artefact removal

Software library for: camera control; calibration; 4D reconstruction; motion analysis; motion artefact removal.

Mid-Term Review Meeting + Workshop 2

Midterm review meeting resp UPC and Workshop 2 organised by USTAN The two events will be colocated and run consecutively

Workshop 1 + Hands on Modules 3+4

Workshop 1 (resp NCU) + Hands on Modules 3+4 (resp. IMO) will be colocated. They will be integrated into one event.

Demonstrators, pilots, prototypes (12)

Prototype of the combined SOFI-Light-Sheet microscope

Prototype of the combined SOFI-Light-Sheet microscope

Prototype and report of a SS-OCT instrument for heart imaging

Prototype and report of an SS-OCT instrument for heart imaging

Prototype of a hyperspectral imaging instrument for the dynamic recording of the ocular fundus

Prototype of a hyperspectral imaging instrument for the dynamic recording of the ocular fundus

Prototype of the endoscopic FRET imaging system
Prototype for Airy beam Light-Sheet microscope

Prototype for an Airy beam Light-Sheet microscope

Prototype of a fluorescence decay based multiplexing system
Demonstration of active spatio-temporal modulation of the phase and amplitude for non-diffractive beam generation
Prototype and report of an OCT system that can be integrated in the instrument for the evaluation of vision in a fully autonomous and automatic way within a clinical environment

Prototype and report of an OCT system that can be integrated in the instrument for the evaluation of vision in a fully autonomous and automatic way within a clinical environment, including control software and user interace.

Prototype of the fibre-optic FRET imaging system
Prototype of the imaging system (optics and electronics)
Prototype and report of a SLO-OCT instrument for opthalmic imaging and its performance for in-vivo imaging

Prototype and report of a SLO-OCT instrument for opthalmic imaging and its performance for in-vivo imaging of the eye

Demonstration of living cell membrane imaging using NS substrates

Documents, reports (17)

Report on the performance of the hyperspectral imaging instrument for the dynamic recording of the ocular fundus
Report on the incoherent emission characteristics of diode light sources under various optical feedback and injection configurations
Report on the performance of the HDA prototype that incorporates the identified incoherent diode-based light source
Report describing the SOFI-Light-Sheet microscope
Report on clinical studies of eyes with ocular diseases
Report describing the Airy beam Light-Sheet microscope
Report on the performance of instrument for the complete evaluation of vision, control software and user interface
Report on novel deconvolution techniques which rectify SOFI brightness skewing by delivering images of linear intensity scaling
Report on the performance of the Airy beam Light-Sheet Microscopy for imaging biological specimens
Report on sample preparation, experimental conditions and data analysis for time-resolved multiplexing in cell microscopy
Report on enhanced light collection of multiphoton confocal function
Report describing the FPGA-based SOFI
Report on the techniques for classification and analysis of 2D images of cardiac and opthalmic images

Report on the performance of novel methods of analysis for classification and analysis of 2D images of cardiac and opthalmic images

Final report
Report on the NS substrate validation with GFP-marked living cells
Report on the performance of the combined SOFI-LSM techniques for imaging life organisms such as nematodes
Report on the performance of the method of reducing refractive index without altering electrical function

Websites, patent fillings, videos etc. (2)

BE-OPTICAL dissemination videos + brochure

BE-OPTICAL dissemination videos + brochure: There will be several of these throughout the project, targetting different sectors and audiences: achivements aimed for the general public; optical imaging achievments aimed at the scientific community; opthalmic achievments (scientfic community)

Patent application

Pubblicazioni

Peer reviewed articles (14)

Wide-field multiphoton imaging through scattering media without correction

Autori: Adrià Escobet-Montalbán, Roman Spesyvtsev, Mingzhou Chen, Wardiya Afshar Saber, Melissa Andrews, C. Simon Herrington, Michael Mazilu, Kishan Dholakia
Pubblicato in: Science Advances, Numero 4/10, 2018, Pagina/e eaau1338, ISSN 2375-2548
Editore: American Association for the Advancement of Science
DOI: 10.1126/sciadv.aau1338

Energy-Reduced Arrhythmia Termination Using Global Photostimulation in Optogenetic Murine Hearts

Autori: Raúl A. Quiñonez Uribe, Stefan Luther, Laura Diaz-Maue, Claudia Richter
Pubblicato in: Frontiers in Physiology, Numero 9, 2018, Pagina/e 1651, ISSN 1664-042X
Editore: Frontiers Research Foundation
DOI: 10.3389/fphys.2018.01651

Unsupervised feature extraction of anterior chamber OCT images for ordering and classification

Autori: Pablo Amil, Laura González, Elena Arrondo, Cecilia Salinas, J. L. Guell, Cristina Masoller, Ulrich Parlitz
Pubblicato in: Scientific Reports, Numero 9/1, 2019, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-018-38136-8

Three-photon light-sheet fluorescence microscopy

Autori: Adrià Escobet-Montalbán, Federico M. Gasparoli, Jonathan Nylk, Pengfei Liu, Zhengyi Yang, and Kishan Dholakia
Pubblicato in: Optics Letters, Numero 43/21, 2018, Pagina/e 5484-5487, ISSN 0146-9592
Editore: Optical Society of America
DOI: 10.17630/ff413c1a-3670-427f-9f3f-670518b172b6

Experimental characterization of the speckle pattern at the output of a multimode optical fiber

Autori: Donatus Halpaap, Jordi Tiana-Alsina, Meritxell Vilaseca, Cristina Masoller
Pubblicato in: Optics Express, Numero 27/20, 2019, Pagina/e 27737, ISSN 1094-4087
Editore: Optical Society of America
DOI: 10.1364/oe.27.027737

Fast visible and extended near-infrared multispectral fundus camera

Autori: Tommaso Alterini; Fernando Díaz-Doutón; Francisco J. Burgos-Fernández; Laura González; Carlos Mateo; Meritxell Vilaseca
Pubblicato in: Journal of Biomedical Optics, Numero 24/09, 2019, Pagina/e 1, ISSN 1083-3668
Editore: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.24.9.096007

High-speed OCT-based ocular biometer combined with an air-puff system for determination of induced retraction-free eye dynamics

Autori: Alfonso Jiménez-villar, Ewa Mączyńska, Artur Cichański, Maciej Wojtkowski, Bartłomiej J. Kałużny, Ireneusz Grulkowski
Pubblicato in: Biomedical Optics Express, Numero 10/7, 2019, Pagina/e 3663, ISSN 2156-7085
Editore: The Optical Society
DOI: 10.1364/boe.10.003663

Spatiotemporal optical coherence (STOC) manipulation suppresses coherent cross-talk in full-field swept-source optical coherence tomography

Autori: Dawid Borycki, Michał Hamkało, Maciej Nowakowski, Maciej Szkulmowski, Maciej Wojtkowski
Pubblicato in: Biomedical Optics Express, Numero 10/4, 2019, Pagina/e 2032, ISSN 2156-7085
Editore: The Optical Society
DOI: 10.1364/boe.10.002032

Air-Puff-Induced Dynamics of Ocular Components Measured with Optical Biometry

Autori: Ewa Maczynska, Jagoda Rzeszewska-Zamiara, Alfonso Jimenez Villar, Maciej Wojtkowski, Bartlomiej J. Kaluzny, Ireneusz Grulkowski
Pubblicato in: Investigative Opthalmology & Visual Science, Numero 60/6, 2019, Pagina/e 1979, ISSN 1552-5783
Editore: ARVO Journals
DOI: 10.1167/iovs.19-26681

Speckle reduction in double-pass retinal images

Autori: Donatus Halpaap, Carlos E. García-Guerra, Meritxell Vilaseca, Cristina Masoller
Pubblicato in: Scientific Reports, Numero 9/1, 2019, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-019-41168-3

Machine learning algorithms for predicting the amplitude of chaotic laser pulses

Autori: Pablo Amil, Miguel C. Soriano, Cristina Masoller
Pubblicato in: Chaos: An Interdisciplinary Journal of Nonlinear Science, Numero 29/11, 2019, Pagina/e 113111, ISSN 1054-1500
Editore: American Institute of Physics
DOI: 10.1063/1.5120755

Optimal compressive multiphoton imaging at depth using single-pixel detection

Autori: Philip Wijesinghe, Adrià Escobet-Montalbán, Mingzhou Chen, Peter R. T. Munro, Kishan Dholakia
Pubblicato in: Optics Letters, Numero 44/20, 2019, Pagina/e 4981, ISSN 0146-9592
Editore: Optical Society of America
DOI: 10.1364/ol.44.004981

Outlier Mining Methods Based on Graph Structure Analysis

Autori: Pablo Amil, Nahuel Almeira, Cristina Masoller
Pubblicato in: Frontiers in Physics, Numero 7, 2019, ISSN 2296-424X
Editore: Frontiers Media S.A
DOI: 10.3389/fphy.2019.00194

Network-based features for retinal fundus vessel structure analysis

Autori: Pablo Amil, Cesar F. Reyes-Manzano, Lev Guzmán-Vargas, Irene Sendiña-Nadal, Cristina Masoller
Pubblicato in: PLOS ONE, Numero 14/7, 2019, Pagina/e e0220132, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0220132

Conference proceedings (2)

Hyperspectral fundus camera with sensitivity beyond the visible range: a pilot study

Autori: Tommaso Alterini; Fernando Díaz-Doutón; Meritxell Vilaseca
Pubblicato in: Investigative Ophthalmology & Visual Science, Numero 59, 2018, Pagina/e 5865
Editore: ARVO Journal

Relation between IOP and air-puff-induced dynamics of ocular components in human eyes measured with full-eye-length SS-OCT

Autori: Ireneusz Grulkowski; Ewa Maczynska; Jagoda Rzeszewska; Alfonso Jimenez-Villar; Maciej Wojtkowski; Bartlomiej Kaluzny
Pubblicato in: Investigative Ophthalmology & Visual Science, Numero 59, 2018, Pagina/e 279
Editore: ARVO Journal

Diritti di proprietà intellettuale

Patent (3)

IMAGE PROCESSING METHOD FOR GLAUCOMA DETECTION AND COMPUTER PROGRAM PRODUCTS THEREOF

Numero candidatura/pubblicazione: 20 17057792
Data: 2017-12-11
Candidato/i: MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV

IMAGE PROCESSING METHOD FOR GLAUCOMA DETECTION AND COMPUTER PROGRAM PRODUCTS THEREOF

Numero candidatura/pubblicazione: 20 17057792
Data: 2017-12-11
Candidato/i: UNIVERSITAT POLITECNICA DE CATALUNYA

IMAGE PROCESSING METHOD FOR GLAUCOMA DETECTION AND COMPUTER PROGRAM PRODUCTS THEREOF

Numero candidatura/pubblicazione: 20 17057792
Data: 2017-12-11
Candidato/i: INSTITUTO DE MICROCIRUGIA OCULAR DOS SLP