Modulation of glycolytic flux as a new approach for treatment of atherosclerosis and plaque stabilization: a multidisciplinary study

Objective

The mission of MoGlyNet is to define a joint doctorate educational training model in Drug Discovery and Development where Academia and Industry join their forces for:
- creating a common platform of knowledge and language for early stage researchers (ESR) working in the Drug Discovery and Development area aiming to convey complementary pharma-skills
- exploiting this platform to train a new generation of cutting-edge researchers and professionals highly attractive for employment by the European Pharma-industry
- establishing structures for long-term cooperation, strengthening the relationships among the leading Universities and Pharma-enterprises and to continuously develop the research training platform that European industry relies on.
To achieve the above objectives the main tasks of MoGlyNet are:
- to attract/train 12 ESRs in optimization joint academic/industrial program of cutting-edge training-by-research, high quality supervision, complementary and transferable Pharma-skills training, inter-network secondments, and workshops/Summer Schools
- to pursue an innovative research project that will tackle a timely and important scientific problem with a multidisciplinary approach (from molecular modelling to in vivo studies). Atherosclerosis is an aging-related disease and our research approach for a better therapy of atherosclerosis will be focused on the PFKFB3 enzyme, a key player in glycolysis/oxidative stress and therefore in pathological angiogenesis
- to build a solid foundation for long-term European excellence in this field by disseminating MoGlyNet research/training outcomes and best practice into the partners Doctoral Schools, and by fostering long-term partnerships and collaborations that will outlast the Consortium
- to transfer expertise/know-how among the Consortium participants and to external groups via networking activities, intersectorial exposure, secondments, workshops, sharing of learning material, public engagement and outreach activities

Field of science

• /medical and health sciences/health sciences/public and environmental health/epidemics prevention/immunisation
• /medical and health sciences/basic medicine/medicinal chemistry
• /natural sciences/biological sciences/biochemistry/biomolecules/proteins/enzymes
• /natural sciences/biological sciences/cell biology/cell metabolism
• /medical and health sciences/clinical medicine/cardiology/cardiovascular diseases/arteriosclerosis
• /social sciences/economics and business/business and management/employment

Programme(s)

• H2020-EU.1.3.1. - Fostering new skills by means of excellent initial training of researchers

Topic(s)

• MSCA-ITN-2015-EJD - Marie Skłodowska-Curie Innovative Training Networks (ITN-EJD)

Call for proposal

H2020-MSCA-ITN-2015
See other projects for this call

Funding Scheme

MSCA-ITN-EJD - European Joint Doctorates

Coordinator

UNIVERSITA DEGLI STUDI DI MILANO

Address

Via Festa Del Perdono 7
20122 Milano
Italy

Activity type

Higher or Secondary Education Establishments

EU contribution

€ 1 032 245,28

Participants (4)

THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN

United Kingdom

EU contribution

€ 546 575,76

Address

King's College Regent Walk
AB24 3FX Aberdeen

Activity type

Higher or Secondary Education Establishments

UNIVERSITEIT ANTWERPEN

Belgium

EU contribution

€ 501 120

Address

Prinsstraat 13
2000 Antwerpen

Activity type

Higher or Secondary Education Establishments

UNIVERSITAT DE BARCELONA

Spain

EU contribution

€ 495 745,92

Address

Gran Via De Les Corts Catalanes 585
08007 Barcelona

Activity type

Higher or Secondary Education Establishments

ACADEMISCH ZIEKENHUIS LEIDEN

Netherlands

EU contribution

€ 510 748,56

Address

Albinusdreef 2
2333 ZA Leiden

Activity type

Higher or Secondary Education Establishments

Partners (8)

Bayer HealthCare Manufacturing S.r.l.

Italy

Address

V.le Certosa, 130
20156 Milano Milano

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

BIOMAX INFORMATICS AG

Germany

Address

Robert Koch Strasse 2
82152 Planegg

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

European Industrial Pharmacists Group

France

Address

4 Avenue Ruysdaël
75379 PARIS Paris

Activity type

Other

HistoGeneX N.V.

Belgium

Address

Pr. J. Charlottelaan 10
2600 Berchem

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

KEMOTECH SRL

Italy

Address

Edificio 3 Localita Piscinamanna
09010 Pula

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

LINKCARE HEALTH SERVICES SL

Spain

Address

Calle Roger De Lluria 50, Sat A
08009 Barcelona

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

Phramintraco

Switzerland

Address

Via Cadepiano 24
6917 Barbengo

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

PPD Italy s.r.l.

Italy

Address

Centro Direzionale Milano Due Palazzo Verrocchio Snc
20090 Segrate Milano

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)