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Modulation of glycolytic flux as a new approach for treatment of atherosclerosis and plaque stabilization: a multidisciplinary study

Objective

The mission of MoGlyNet is to define a joint doctorate educational training model in Drug Discovery and Development where Academia and Industry join their forces for:
- creating a common platform of knowledge and language for early stage researchers (ESR) working in the Drug Discovery and Development area aiming to convey complementary pharma-skills
- exploiting this platform to train a new generation of cutting-edge researchers and professionals highly attractive for employment by the European Pharma-industry
- establishing structures for long-term cooperation, strengthening the relationships among the leading Universities and Pharma-enterprises and to continuously develop the research training platform that European industry relies on.
To achieve the above objectives the main tasks of MoGlyNet are:
- to attract/train 12 ESRs in optimization joint academic/industrial program of cutting-edge training-by-research, high quality supervision, complementary and transferable Pharma-skills training, inter-network secondments, and workshops/Summer Schools
- to pursue an innovative research project that will tackle a timely and important scientific problem with a multidisciplinary approach (from molecular modelling to in vivo studies). Atherosclerosis is an aging-related disease and our research approach for a better therapy of atherosclerosis will be focused on the PFKFB3 enzyme, a key player in glycolysis/oxidative stress and therefore in pathological angiogenesis
- to build a solid foundation for long-term European excellence in this field by disseminating MoGlyNet research/training outcomes and best practice into the partners Doctoral Schools, and by fostering long-term partnerships and collaborations that will outlast the Consortium
- to transfer expertise/know-how among the Consortium participants and to external groups via networking activities, intersectorial exposure, secondments, workshops, sharing of learning material, public engagement and outreach activities

Field of science

  • /medical and health sciences/health sciences/public and environmental health/epidemics prevention/immunisation
  • /medical and health sciences/basic medicine/medicinal chemistry
  • /natural sciences/biological sciences/biochemistry/biomolecules/proteins/enzymes
  • /natural sciences/biological sciences/cell biology/cell metabolism
  • /medical and health sciences/clinical medicine/cardiology/cardiovascular diseases/arteriosclerosis
  • /social sciences/economics and business/business and management/employment

Call for proposal

H2020-MSCA-ITN-2015
See other projects for this call

Funding Scheme

MSCA-ITN-EJD - European Joint Doctorates

Coordinator

UNIVERSITA DEGLI STUDI DI MILANO
Address
Via Festa Del Perdono 7
20122 Milano
Italy
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 032 245,28

Participants (4)

THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN
United Kingdom
EU contribution
€ 546 575,76
Address
King's College Regent Walk
AB24 3FX Aberdeen
Activity type
Higher or Secondary Education Establishments
UNIVERSITEIT ANTWERPEN
Belgium
EU contribution
€ 501 120
Address
Prinsstraat 13
2000 Antwerpen
Activity type
Higher or Secondary Education Establishments
UNIVERSITAT DE BARCELONA
Spain
EU contribution
€ 495 745,92
Address
Gran Via De Les Corts Catalanes 585
08007 Barcelona
Activity type
Higher or Secondary Education Establishments
ACADEMISCH ZIEKENHUIS LEIDEN
Netherlands
EU contribution
€ 510 748,56
Address
Albinusdreef 2
2333 ZA Leiden
Activity type
Higher or Secondary Education Establishments

Partners (8)

Bayer HealthCare Manufacturing S.r.l.
Italy
Address
V.le Certosa, 130
20156 Milano Milano
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
BIOMAX INFORMATICS AG
Germany
Address
Robert Koch Strasse 2
82152 Planegg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
European Industrial Pharmacists Group
France
Address
4 Avenue Ruysdaël
75379 PARIS Paris
Activity type
Other
HistoGeneX N.V.
Belgium
Address
Pr. J. Charlottelaan 10
2600 Berchem
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
KEMOTECH SRL
Italy
Address
Edificio 3 Localita Piscinamanna
09010 Pula
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
LINKCARE HEALTH SERVICES SL
Spain
Address
Calle Roger De Lluria 50, Sat A
08009 Barcelona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Phramintraco
Switzerland
Address
Via Cadepiano 24
6917 Barbengo
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
PPD Italy s.r.l.
Italy
Address
Centro Direzionale Milano Due Palazzo Verrocchio Snc
20090 Segrate Milano
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)