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Programmable BioMolecular Circuits: Emulating Regulatory Functions in Living Cells Using a Bottom-Up Approach

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Publications

Hierarchical control of enzymatic actuators using DNA-based switchable memories

Author(s): Lenny H. H. Meijer, Alex Joesaar, Erik Steur, Wouter Engelen, Rutger A. van Santen, Maarten Merkx, Tom F. A. de Greef
Published in: Nature Communications, Issue 8/1, 2017, ISSN 2041-1723
DOI: 10.1038/s41467-017-01127-w

DNA-Based Nanodevices Controlled by Purely Entropic Linker Domains

Author(s): Davide Mariottini, Andrea Idili, Minke A. D. Nijenhuis, Tom F. A. de Greef, Francesco Ricci
Published in: Journal of the American Chemical Society, Issue 140/44, 2018, Page(s) 14725-14734, ISSN 0002-7863
DOI: 10.1021/jacs.8b07640

Cell-free microcompartmentalised transcription–translation for the prototyping of synthetic communication networks

Author(s): Emilien Dubuc, Pascal A Pieters, Ardjan J van der Linden, Jan CM van Hest, Wilhelm TS Huck, Tom FA de Greef
Published in: Current Opinion in Biotechnology, Issue 58, 2019, Page(s) 72-80, ISSN 0958-1669
DOI: 10.1016/j.copbio.2018.10.006

Sigma Factor-Mediated Tuning of Bacterial Cell-Free Synthetic Genetic Oscillators

Author(s): Maaruthy Yelleswarapu, Ardjan J. van der Linden, Bob van Sluijs, Pascal A. Pieters, Emilien Dubuc, Tom F. A. de Greef, Wilhelm T. S. Huck
Published in: ACS Synthetic Biology, Issue 7/12, 2018, Page(s) 2879-2887, ISSN 2161-5063
DOI: 10.1021/acssynbio.8b00300

DNA-based communication in populations of synthetic protocells

Author(s): Alex Joesaar, Shuo Yang, Bas Bögels, Ardjan van der Linden, Pascal Pieters, B. V. V. S. Pavan Kumar, Neil Dalchau, Andrew Phillips, Stephen Mann, Tom F. A. de Greef
Published in: Nature Nanotechnology, Issue 14/4, 2019, Page(s) 369-378, ISSN 1748-3387
DOI: 10.1038/s41565-019-0399-9

Pathway Control in Cooperative vs. Anti-Cooperative Supramolecular Polymers


Published in: ISSN 1433-7851
DOI: 10.1002/anie.201905064

Counterion-Dependent Mechanisms of DNA Origami Nanostructure Stabilization Revealed by Atomistic Molecular Simulation

Author(s): Job A. L. Roodhuizen, Philip J. T. M. Hendrikx, Peter A. J. Hilbers, Tom F. A. de Greef, Albert J. Markvoort
Published in: ACS Nano, 2019, ISSN 1936-0851
DOI: 10.1021/acsnano.9b05650

Incorporation of native antibodies and Fc-fusion proteins on DNA nanostructures via a modular conjugation strategy

Author(s): Bas J. H. M. Rosier, Glenn A. O. Cremers, Wouter Engelen, Maarten Merkx, Luc Brunsveld, Tom F. A. de Greef
Published in: Chem. Commun., Issue 53/53, 2017, Page(s) 7393-7396, ISSN 1359-7345
DOI: 10.1039/C7CC04178K

Small-Molecule-Induced and Cooperative Enzyme Assembly on a 14-3-3 Scaffold


Published in: ISSN 1439-4227
DOI: 10.1002/cbic.201600631

Antibody-controlled actuation of DNA-based molecular circuits

Author(s): Wouter Engelen, Lenny H. H. Meijer, Bram Somers, Tom F. A. de Greef, Maarten Merkx
Published in: Nature Communications, Issue 8, 2017, Page(s) 14473, ISSN 2041-1723
DOI: 10.1038/ncomms14473

Non-equilibrium supramolecular polymerization

Author(s): Alessandro Sorrenti, Jorge Leira-Iglesias, Albert J. Markvoort, Tom F. A. de Greef, Thomas M. Hermans
Published in: Chem. Soc. Rev., 2017, ISSN 0306-0012
DOI: 10.1039/C7CS00121E