Origins of Alzheimer's disease across the life-course

Informazioni relative al progetto

ORACLE

ID dell’accordo di sovvenzione: 678543

DOI 10.3030/678543

Progetto chiuso

Data della firma CE 7 Giugno 2016

Data di avvio 1 Settembre 2016

Data di completamento 28 Febbraio 2022

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 495 715,00

Contributo UE € 1 495 715,00

Coordinato da

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands

Pubblicazioni

Peer reviewed articles (18)

Cortical gyrification in relation to age and cognition in older adults.

Autori: Sander Lamballais; Elisabeth J Vinke; Meike W. Vernooij; M. Arfan Ikram; Ryan L. Muetzel
Pubblicato in: Neuroimage, Numero 1, 2020, ISSN 1053-8119
Editore: Academic Press
DOI: 10.1016/j.neuroimage.2020.116637

Sociodemographic, Lifestyle, Physical, and Psychosocial Determinants of Cognitive Reserve

Autori: Jendé L Zijlmans, Sander Lamballais, Meike W Vernooij, M Arfan Ikram, Annemarie I Luik
Pubblicato in: Journal of Alzheimer's disease, 2022, ISSN 1387-2877
Editore: IOS Press
DOI: 10.3233/jad-215122

Life Expectancy With and Without Dementia: A Population-Based Study of Dementia Burden and Preventive Potential.

Autori: Frank J. Wolters; Liselotte M Tinga; Klodian Dhana; Klodian Dhana; Klodian Dhana; Peter J. Koudstaal; Albert Hofman; Daniel Bos; Oscar H. Franco; M. Arfan Ikram
Pubblicato in: American Journal of Epidemiology, Numero 1, 2019, ISSN 1476-6256
Editore: Oxford University Press
DOI: 10.1093/aje/kwy234

Genetic scores for adult subcortical volumes associate with subcortical volumes during infancy and childhood.

Autori: Sander Lamballais; Philip R. Jansen; Jeremy A. Labrecque; M. Arfan Ikram; Tonya White
Pubblicato in: Human Brain Mapping, 42(6), 1583 - 1593. Wiley-Liss Inc., Numero 1, 2021, ISSN 1097-0193
Editore: Wiley Periodicals
DOI: 10.1002/hbm.25292

Implementation and validation of ASL perfusion measurements for population imaging

Autori: Esther A. H. Warnert; Rebecca M. E. Steketee; Meike W. Vernooij; M. Arfan Ikram; Mika W. Vogel; Juan‐Antonio Hernandez Tamames; Gyula Kotek
Pubblicato in: Magnetic Resonance in Medicine, Numero 1, 2020, ISSN 1522-2594
Editore: Wiley
DOI: 10.1002/mrm.28271

Heritability of the shape of subcortical brain structures in the general population

Autori: Gennady V. Roshchupkin, Boris A. Gutman, Meike W. Vernooij, Neda Jahanshad, Nicholas G. Martin, Albert Hofman, Katie L. McMahon, Sven J. van der Lee, Cornelia M. van Duijn, Greig I. de Zubicaray, André G. Uitterlinden, Margaret J. Wright, Wiro J. Niessen, Paul M. Thompson, M. Arfan Ikram, Hieab H. H. Adams
Pubblicato in: Nature Communications, Numero 7, 2016, Pagina/e 13738, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/ncomms13738

Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium

Autori: Lori B. Chibnik, Frank J. Wolters, Kristoffer Bäckman, Alexa Beiser, Claudine Berr, Joshua C. Bis, Eric Boerwinkle, Daniel Bos, Carol Brayne, Jean-Francois Dartigues, Sirwan K. L. Darweesh, Stephanie Debette, Kendra L. Davis-Plourde, Carole Dufouil, Myriam Fornage, Leslie Grasset, Vilmundur Gudnason, Christoforos Hadjichrysanthou, Catherine Helmer, M. Arfan Ikram, M. Kamran Ikram, Silke Kern, Lew
Pubblicato in: European Journal of Epidemiology, Numero 32/10, 2017, Pagina/e 931-938, ISSN 0393-2990
Editore: Kluwer Academic Publishers
DOI: 10.1007/s10654-017-0320-5

Novel genetic loci underlying human intracranial volume identified through genome-wide association

Autori: Hieab H H Adams, Derrek P Hibar, Vincent Chouraki, Jason L Stein, Paul A Nyquist, Miguel E Rentería, Stella Trompet, Alejandro Arias-Vasquez, Sudha Seshadri, Sylvane Desrivières, Ashley H Beecham, Neda Jahanshad, Katharina Wittfeld, Sven J Van der Lee, Lucija Abramovic, Saud Alhusaini, Najaf Amin, Micael Andersson, Konstantinos Arfanakis, Benjamin S Aribisala, Nicola J Armstrong, Lavinia Athanas
Pubblicato in: Nature Neuroscience, Numero 19/12, 2016, Pagina/e 1569-1582, ISSN 1097-6256
Editore: Nature Publishing Group
DOI: 10.1038/nn.4398

HASE: Framework for efficient high-dimensional association analyses

Autori: G. V. Roshchupkin, H. H. H. Adams, M. W. Vernooij, A. Hofman, C. M. Van Duijn, M. A. Ikram, W. J. Niessen
Pubblicato in: Scientific Reports, Numero 6/1, 2016, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/srep36076

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

Autori: Dina Vojinovic, Hieab H. Adams, Xueqiu Jian, Qiong Yang, Albert Vernon Smith, Joshua C. Bis, Alexander Teumer, Markus Scholz, Nicola J. Armstrong, Edith Hofer, Yasaman Saba, Michelle Luciano, Manon Bernard, Stella Trompet, Jingyun Yang, Nathan A. Gillespie, Sven J. van der Lee, Alexander Neumann, Shahzad Ahmad, Ole A. Andreassen, David Ames, Najaf Amin, Konstantinos Arfanakis, Mark E. Bastin, Dian
Pubblicato in: Nature Communications, Numero 9/1, 2018, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-018-06234-w

Genetic variation underlying cognition and its relation with neurological outcomes and brain imaging

Autori: Maria J. Knol, Alis Heshmatollah, Lotte G.M. Cremers, M. Kamran Ikram, André G. Uitterlinden, Cornelia M. van Duijn, Wiro J. Niessen, Meike W. Vernooij, M. Arfan Ikram, Hieab H.H. Adams
Pubblicato in: Aging, Numero 11/5, 2019, Pagina/e 1440-1456, ISSN 1945-4589
Editore: Impact Journals LLC
DOI: 10.18632/aging.101844

Translational research on reserve against neurodegenerative disease: consensus report of the International Conference on Cognitive Reserve in the Dementias and the Alzheimer’s Association Reserve, Resilience and Protective Factors Professional Interest Area working groups

Autori: Robert Perneczky, Gerd Kempermann, Amos D. Korczyn, Fiona E. Matthews, M. Arfan Ikram, Nikolaos Scarmeas, Gael Chetelat, Yaakov Stern, Michael Ewers
Pubblicato in: BMC Medicine, Numero 17/1, 2019, ISSN 1741-7015
Editore: BioMed Central
DOI: 10.1186/s12916-019-1283-z

Association of Blood Pressure and Arterial Stiffness With Cognition in 2 Population‐Based Child and Adult Cohorts

Autori: Sander Lamballais, Ayesha Sajjad, Maarten J. G. Leening, Romy Gaillard, Oscar H. Franco, Francesco U. S. Mattace‐Raso, Vincent W. V. Jaddoe, Sabine J. Roza, Henning Tiemeier, M. Arfan Ikram
Pubblicato in: Journal of the American Heart Association, Numero 7/21, 2018, ISSN 2047-9980
Editore: Wiley-Blackwell
DOI: 10.1161/jaha.118.009847

Trajectories of imaging markers in brain aging: the Rotterdam Study

Autori: Elisabeth J. Vinke, Marius de Groot, Vikram Venkatraghavan, Stefan Klein, Wiro J. Niessen, M. Arfan Ikram, Meike W. Vernooij
Pubblicato in: Neurobiology of Aging, Numero 71, 2018, Pagina/e 32-40, ISSN 0197-4580
Editore: Elsevier BV
DOI: 10.1016/j.neurobiolaging.2018.07.001

Design and overview of the Origins of Alzheimer's Disease Across the Life course (ORACLE) study

Autori: Sander Lamballais; Maria C. Adank; Rowina F. Hussainali; Sarah Schalekamp-Timmermans; Meike W. Vernooij; Annemarie I. Luik; Eric A.P. Steegers; Mohammad Arfan Ikram
Pubblicato in: European Journal of Epidemiology, Numero 1, 2021, ISSN 1573-7284
Editore: Springer
DOI: 10.1007/s10654-020-00696-3

Child mental health problems as a risk factor for academic underachievement: A multi‐informant, population‐based study

Autori: Isabel K. Schuurmans; Nathalie Tamayo Martinez; Elisabet Blok; Manon H. J. Hillegers; M. Arfan Ikram; Annemarie I. Luik; Charlotte A. M. Cecil
Pubblicato in: Acta Psychiatrica Scandinavica, Numero 146(6), 2022, Pagina/e 578-590, ISSN 1600-0447
Editore: Wiley
DOI: 10.1111/acps.13426

Genetic determinants of cortical structure (thickness, surface area and volumes) among disease free adults in the CHARGE Consortium

Autori: Hofer, Edith; Roshchupkin, Gennady V.; Adams, Hieab H. H.; Knol, Maria J.; Lin, Honghuang; Li, Shuo; Zare, Habil; Ahmad, Shahzad; Armstrong, Nicola J.; Satizabal, Claudia L.; Bernard, Manon; Bis, Joshua C.; Gillespie, Nathan A.; Luciano, Michelle; Mishra, Aniket; Scholz, Markus; Teumer, Alexander; Xia, Rui; Jian, Xueqiu; Mosley, Thomas H.; Saba, Yasaman; Pirpamer, Lukas; Seiler, Stephan; Becker, J
Pubblicato in: Nature Communications, Numero 1, 2020, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-020-18367-y

Genetic Burden for Late-Life Neurodegenerative Disease and Its Association With Early-Life Lipids, Brain, Behavior, and Cognition

Autori: Sander Lamballais; Ryan L. Muetzel; Ryan L. Muetzel; Mohammad Arfan Ikram; Henning Tiemeier; Henning Tiemeier; Meike W. Vernooij; Meike W. Vernooij; Tonya White; Tonya White; Hieab H. H. Adams; Hieab H. H. Adams; Hieab H. H. Adams
Pubblicato in: Frontiers in Psychiatry, 11, Numero 1, 2020, ISSN 1664-0640
Editore: Frontiers Research Foundation
DOI: 10.3389/fpsyt.2020.00033