Understanding and manipulating the dynamics of chromosome topologies in transcriptional control

Project Information

CHROMTOPOLOGY

Grant agreement ID: 678624

DOI 10.3030/678624

Project closed

EC signature date 30 May 2016

Start date 1 June 2016

End date 31 December 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 500 000,00

EU contribution € 1 500 000,00

Coordinated by

CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (8)

Integration of high-throughput reporter assays identify a critical enhancer of the Ikzf1 gene.

Author(s): Jaafar Alomairi; Anne Molitor; Nori Sadouni; Saadat Hussain; Magali Torres; Wiam Saadi; Lan T.M. Dao; Guillaume Charbonnier; David Santiago-Algarra; Jean-Christophe Andrau; Denis Puthier; Tom Sexton; Salvatore Spicuglia
Published in: PLoS ONE, Issue 15(5), 2020, Page(s) pp.e0233191, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0233191

Precise measurements of chromatin diffusion dynamics by modeling using Gaussian processes

Author(s): Guilherme M Oliveira, Attila Oravecz, Dominique Kobi, Manon Maroquenne, Kerstin Bystricky, Tom Sexton, Nacho Molina
Published in: Nature Communications, Issue 12(1), 2021, Page(s) 6184, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-26466-7

Myod1 and GR coordinate myofiber-specific transcriptional enhancers

Author(s): Daniela Rovito, Anna-Isavella Rerra, Vanessa Ueberschlag-Pitiot, Shilpy Joshi, Nezih Karasu, Vanessa Dacleu-Siewe, Khalil Ben Rayana, Kamar Ghaibour, Maxime Parisotto, Arnaud Ferry, Scott A Jelinsky, Gilles Laverny, Bruno P Klaholz, Tom Sexton, Isabelle M L Billas, Delphine Duteil, Daniel Metzger
Published in: Nucleic Acids Res, Issue 49(8), 2021, Page(s) 4472-4492, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkab226

Alternative Enhancer Usage and Targeted Polycomb Marking Hallmark Promoter Choice during T Cell Differentiation

Author(s): Muhammad Ahmad Maqbool; Léo Pioger; Amal Zine El Aabidine; Nezih Karasu; Anne Molitor; Lan T.M. Dao; Guillaume Charbonnier; Francois van Laethem; Romain Fenouil; Frederic Koch; Georges Lacaud; Ivo Gut; Marta Gut; Sebastian Amigorena; Olivier Joffre; Tom Sexton; Salvatore Spicuglia; Jean-Christophe Andrau
Published in: https://hal-amu.archives-ouvertes.fr/hal-03015018, Issue 4, 2020, Page(s) 108048, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2020.108048

Age-related and disease locus-specific mechanisms contribute to early remodelling of chromatin structure in Huntington's disease mice

Author(s): Rafael Alcalá-Vida, Jonathan Seguin, Caroline Lotz, Anne M Molitor, Ibai Irastorza-Azcarate, Ali Awada, Nezih Karasu, Aurélie Bombardier, Brigitte Cosquer, Jose Luis Gomez Skarmeta , Jean-Christophe Cassel, Anne-Laurence Boutillier, Thomas Sexton, Karine Merienne
Published in: Nature Communications, Issue 12(1), 2021, Page(s) 364, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-20605-2

Defining Functionally Relevant Spatial Chromatin Domains: It is a TAD Complicated

Author(s): Natalia Sikorska, Tom Sexton
Published in: J. Mol. Biol., Issue 432(3), 2020, Page(s) 653-664, ISSN 0022-2836
Publisher: Academic Press
DOI: 10.1016/j.jmb.2019.12.006

ChiCMaxima: a robust and simple pipeline for detection and visualization of chromatin looping in Capture Hi-C

Author(s): Yousra Ben Zouari, Anne M. Molitor, Natalia Sikorska, Vera Pancaldi, Tom Sexton
Published in: Genome Biology, Issue 20/1, 2019, ISSN 1474-760X
Publisher: BMC
DOI: 10.1186/s13059-019-1706-3

4See: A Flexible Browser to Explore 4C Data

Author(s): Yousra Ben Zouari, Angeliki Platania, Anne M. Molitor, Tom Sexton
Published in: Frontiers in Genetics, Issue 10, 2020, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2019.01372

Other (4)

Additional file 1: of ChiCMaxima: a robust and simple pipeline for detection and visualization of chromatin looping in Capture Hi-C

Author(s): Zouari, Yousra Ben; Molitor, Anne; Sikorska, Natalia; Pancaldi, Vera; Sexton, Tom
Published in: Genome Biology, Issue 20(1), 2021, Page(s) 6184, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.6084/m9.figshare.8172704

Additional file 3: of ChiCMaxima: a robust and simple pipeline for detection and visualization of chromatin looping in Capture Hi-C

Author(s): Zouari, Yousra Ben; Molitor, Anne; Sikorska, Natalia; Pancaldi, Vera; Sexton, Tom
Published in: Genome Biology, Issue 20(1), 2021, Page(s) 6184, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.6084/m9.figshare.8172722.v1

Additional file 2: of ChiCMaxima: a robust and simple pipeline for detection and visualization of chromatin looping in Capture Hi-C

Author(s): Zouari, Yousra Ben; Molitor, Anne; Sikorska, Natalia; Pancaldi, Vera; Sexton, Tom
Published in: Genome Biology, Issue 20(1), 2019, ISSN 1474-760X
Publisher: Biomed Central
DOI: 10.6084/m9.figshare.8172713.v1

Transcriptional regulation and chromatin architecture maintenance are decoupled modular functions at the Sox2 locus

Author(s): Tiegh Taylor, Natalia Sikorska, Virlana M Shchuka, Sanjay Chahar, Chenfan Ji, Neil N Macpherson, Sakthi D Moorthy, Jennifer A Mitchell, Tom Sexton
Published in: bioRxiv, 2022
Publisher: Preprint
DOI: 10.1101/2022.02.09.479674