Cerebellar modules and the Ontogeny of Sensorimotor Integration

Informazioni relative al progetto

COSI

ID dell’accordo di sovvenzione: 680235

DOI 10.3030/680235

Progetto chiuso

Data della firma CE 10 Marzo 2016

Data di avvio 1 Giugno 2016

Data di completamento 30 Novembre 2021

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 500 000,00

Contributo UE € 1 500 000,00

Coordinato da

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands

Pubblicazioni

Peer reviewed articles (11)

Differential spatiotemporal development of Purkinje cell populations and cerebellum-dependent sensorimotor behaviors

Autori: Gerrit Cornelis Beekhof; Catarina Osório; Joshua J White; Scott van Zoomeren; Hannah van der Stok; Bilian Xiong; Ingo HMS Nettersheim; Willem Ashwin Mak; Marit Runge; Francesca Romana Fiocchi; Henk-Jan Boele; Freek E Hoebeek; Martijn Schonewille
Pubblicato in: eLife, Numero 1, 2021, Pagina/e 63668, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.63668

TRPC3 is a major contributor to functional heterogeneity of cerebellar Purkinje cells.

Autori: Wu, Bin; Blot, François GC; Wong, Aaron Benson; Osório, Catarina; Adolfs, Youri; Pasterkamp, R Jeroen; Hartmann, Jana; Becker, Esther BE; Boele, Henk-Jan; De Zeeuw, Chris I; Schonewille, Martijn
Pubblicato in: VOLUME=8;ISSN=2050-084X;TITLE=eLife, Numero 2, 2019, Pagina/e 45590, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.45590

AMPAR Auxiliary Protein SHISA6 Facilitates Purkinje Cell Synaptic Excitability and Procedural Memory Formation

Autori: Saša Peter, Bastiaan H A Urbanus, Remco V Klaassen, Bin Wu, Henk-Jan Boele, Sameha Azizi, Johan A Slotman, Adriaan B Houtsmuller, Martijn Schonewille, Freek E Hoebeek, Sabine Spijker, August B Smit, Chris I De Zeeuw
Pubblicato in: Cell Reports, Numero 31(2), 2020, Pagina/e 107515, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2020.03.079

Purkinje cell axonal swellings enhance action potential fidelity and cerebellar function

Autori: Daneck Lang-Ouellette, Kim M. Gruver, Amy Smith-Dijak, François G. C. Blot, Chloe A. Stewart, Pauline de Vanssay de Blavous, Connie H. Li, Carter Van Eitrem, Charlotte Rosen, Phyllis L. Faust, Martijn Schonewille, Alanna J. Watt
Pubblicato in: Nature Communications, Numero 12, 2021, Pagina/e 4129, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-021-24390-4

Activity of Cerebellar Nuclei Neurons Correlates with ZebrinII Identity of Their Purkinje Cell Afferents

Autori: Gerrit C. Beekhof; Simona V. Gornati; Cathrin B. Canto; Avraham M. Libster; Martijn Schonewille; Chris I. De Zeeuw; Freek E. Hoebeek
Pubblicato in: Cells, Numero 10(10), 2021, Pagina/e 2686, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells10102686

Mechanisms underlying vestibulo-cerebellar motor learning in mice depend on movement direction

Autori: Kai Voges, Bin Wu, Laura Post, Martijn Schonewille, Chris I. De Zeeuw
Pubblicato in: The Journal of Physiology, Numero 595/15, 2017, Pagina/e 5301-5326, ISSN 0022-3751
Editore: Blackwell Publishing Inc.
DOI: 10.1113/JP274346

Impact of NMDA Receptor Overexpression on Cerebellar Purkinje Cell Activity and Motor Learning

Autori: Elisa Galliano, Martijn Schonewille, Saša Peter, Mandy Rutteman, Simone Houtman, Dick Jaarsma, Freek E. Hoebeek, Chris I. De Zeeuw
Pubblicato in: eneuro, Numero 5/1, 2018, Pagina/e ENEURO.0270-17.2018, ISSN 2373-2822
Editore: Society for Neuroscience
DOI: 10.1523/eneuro.0270-17.2018

The basal interstitial nucleus (BIN) of the cerebellum provides diffuse ascending inhibitory input to the floccular granule cell layer

Autori: Dick Jaarsma, Francois G. C. Blot, Bin Wu, Subramanian Venkatesan, Jan Voogd, Dies Meijer, Tom J. H. Ruigrok, Zhenyu Gao, Martijn Schonewille, Chris I. De Zeeuw
Pubblicato in: Journal of Comparative Neurology, Numero 526/14, 2018, Pagina/e 2231-2256, ISSN 0021-9967
Editore: John Wiley & Sons Inc.
DOI: 10.1002/cne.24479

Cerebellar Modules and Their Role as Operational Cerebellar Processing Units

Autori: Richard Apps, Richard Hawkes, Sho Aoki, Fredrik Bengtsson, Amanda M. Brown, Gang Chen, Timothy J. Ebner, Philippe Isope, Henrik Jörntell, Elizabeth P. Lackey, Charlotte Lawrenson, Bridget Lumb, Martijn Schonewille, Roy V. Sillitoe, Ludovic Spaeth, Izumi Sugihara, Antoine Valera, Jan Voogd, Douglas R. Wylie, Tom J. H. Ruigrok
Pubblicato in: The Cerebellum, Numero 17/5, 2018, Pagina/e 654-682, ISSN 1473-4222
Editore: Springer New York
DOI: 10.1007/s12311-018-0952-3

Sphingolipid metabolism governs Purkinje cell patterned degeneration in Atxn1[82Q]/+ mice

Autori: François G. C. Blot, Wilhelmina H. J. J. Krijnen, Sandra Den Hoedt, Catarina Osório, Joshua J. White, Monique T. Mulder, Martijn Schonewille
Pubblicato in: Proceedings of the National Academy of Sciences of the United States of America, Numero 118(36), 2021, Pagina/e e2016969118, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2016969118

Region-specific preservation of Purkinje cell morphology and motor behavior in the ATXN1[82Q] mouse model of spinocerebellar ataxia 1

Autori: Joshua J. White; Laurens W. J. Bosman; Francois G. C. Blot; Catarina Osório; Bram W. Kuppens; Wilhelmina H. J. J. Krijnen; Charlotte Andriessen; Chris I. De Zeeuw; Dick Jaarsma; Martijn Schonewille
Pubblicato in: Brain Pathology, Numero 1, 2021, Pagina/e e12946., ISSN 1750-3639
Editore: Brain Pathology
DOI: 10.1111/bpa.12946