Publications Peer reviewed articles (24) Identifying proteins bound to native mitotic ESC chromosomes reveals chromatin repressors are important for compaction Author(s): Dounia Djeghloul, Bhavik Patel, Holger Kramer, Andrew Dimond, Chad Whilding, Karen Brown, Anne-Céline Kohler, Amelie Feytout, Nicolas Veland, James Elliott, Tanmay A. M. Bharat, Abul K. Tarafder, Jan Löwe, Bee L. Ng, Ya Guo, Jacky Guy, Miles K. Huseyin, Robert J. Klose, Matthias Merkenschlager, Amanda G. Fisher Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-020-17823-z The SET1 Complex Selects Actively Transcribed Target Genes via Multivalent Interaction with CpG Island Chromatin Author(s): David A. Brown, Vincenzo Di Cerbo, Angelika Feldmann, Jaewoo Ahn, Shinsuke Ito, Neil P. Blackledge, Manabu Nakayama, Michael McClellan, Emilia Dimitrova, Anne H. Turberfield, Hannah K. Long, Hamish W. King, Skirmantas Kriaucionis, Lothar Schermelleh, Tatiana G. Kutateladze, Haruhiko Koseki, Robert J. Klose Published in: Cell Reports, Issue 20/10, 2017, Page(s) 2313-2327, ISSN 2211-1247 Publisher: Cell Press DOI: 10.1016/j.celrep.2017.08.030 ATACing DNA Methylation during Differentiation Author(s): Skirmantas Kriaucionis, Robert J. Klose Published in: Molecular Cell, Issue 77/6, 2020, Page(s) 1159-1161, ISSN 1097-2765 Publisher: Cell Press DOI: 10.1016/j.molcel.2020.02.026 RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes Author(s): Nathan R Rose, Hamish W King, Neil P Blackledge, Nadezda A Fursova, Katherine JI Ember, Roman Fischer, Benedikt M Kessler, Robert J Klose Published in: eLife, Issue 5, 2016, ISSN 2050-084X Publisher: eLife Sciences Publications DOI: 10.7554/elife.18591 KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity Author(s): Anne H Turberfield, Takashi Kondo, Manabu Nakayama, Yoko Koseki, Hamish W King, Haruhiko Koseki, Robert J Klose Published in: Nucleic Acids Research, Issue 47/17, 2019, Page(s) 9005-9023, ISSN 0305-1048 Publisher: Oxford University Press DOI: 10.1093/nar/gkz607 BAP1 constrains pervasive H2AK119ub1 to control the transcriptional potential of the genome Author(s): Nadezda A. Fursova, Anne H. Turberfield, Neil P. Blackledge, Emma L. Findlater, Anna Lastuvkova, Miles K. Huseyin, Paula Dobrinić, Robert J. Klose Published in: Genes & Development, Issue 35/9-10, 2021, Page(s) 749-770, ISSN 0890-9369 Publisher: Cold Spring Harbor Laboratory Press DOI: 10.1101/gad.347005.120 PRC1 Catalytic Activity Is Central to Polycomb System Function Author(s): Neil P. Blackledge, Nadezda A. Fursova, Jessica R. Kelley, Miles K. Huseyin, Angelika Feldmann, Robert J. Klose Published in: Molecular Cell, Issue 77/4, 2020, Page(s) 857-874.e9, ISSN 1097-2765 Publisher: Cell Press DOI: 10.1016/j.molcel.2019.12.001 CDK-Mediator and FBXL19 prime developmental genes for activation by promoting atypical regulatory interactions Author(s): Angelika Feldmann, Emilia Dimitrova, Alexander Kenney, Anna Lastuvkova, Robert J Klose Published in: Nucleic Acids Research, Issue 48/6, 2020, Page(s) 2942-2955, ISSN 0305-1048 Publisher: Oxford University Press DOI: 10.1093/nar/gkaa064 Getting under the skin of Polycomb-dependent gene regulation Author(s): Neil P. Blackledge, Robert J. Klose Published in: Genes & Development, Issue 35/5-6, 2021, Page(s) 301-303, ISSN 0890-9369 Publisher: Cold Spring Harbor Laboratory Press DOI: 10.1101/gad.348257.121 Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression Author(s): Nadezda A. Fursova, Neil P. Blackledge, Manabu Nakayama, Shinsuke Ito, Yoko Koseki, Anca M. Farcas, Hamish W. King, Haruhiko Koseki, Robert J. Klose Published in: Molecular Cell, Issue 74/5, 2019, Page(s) 1020-1036.e8, ISSN 1097-2765 Publisher: Cell Press DOI: 10.1016/j.molcel.2019.03.024 FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment Author(s): Emilia Dimitrova, Takashi Kondo, Angelika Feldmann, Manabu Nakayama, Yoko Koseki, Rebecca Konietzny, Benedikt M Kessler, Haruhiko Koseki, Robert J Klose Published in: eLife, Issue 7, 2018, ISSN 2050-084X Publisher: eLife Sciences Publications DOI: 10.7554/elife.37084 Distinct contributions of DNA methylation and histone acetylation to the genomic occupancy of transcription factors Author(s): Martin Cusack, Hamish W. King, Paolo Spingardi, Benedikt M. Kessler, Robert J. Klose, Skirmantas Kriaucionis Published in: Genome Research, Issue 30/10, 2020, Page(s) 1393-1406, ISSN 1088-9051 Publisher: Cold Spring Harbor Laboratory Press DOI: 10.1101/gr.257576.119 Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy Author(s): Miles K. Huseyin, Robert J. Klose Published in: Nature Communications, Issue 12/1, 2021, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-021-21130-6 Polycomb repressive complex 1 shapes the nucleosome landscape but not accessibility at target genes Author(s): Hamish W. King, Nadezda A. Fursova, Neil P. Blackledge, Robert J. Klose Published in: Genome Research, Issue 28/10, 2018, Page(s) 1494-1507, ISSN 1088-9051 Publisher: Cold Spring Harbor Laboratory Press DOI: 10.1101/gr.237180.118 MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia Author(s): Jon Kerry, Laura Godfrey, Emmanouela Repapi, Marta Tapia, Neil P. Blackledge, Helen Ma, Erica Ballabio, Sorcha O’Byrne, Frida Ponthan, Olaf Heidenreich, Anindita Roy, Irene Roberts, Marina Konopleva, Robert J. Klose, Huimin Geng, Thomas A. Milne Published in: Cell Reports, Issue 18/2, 2017, Page(s) 482-495, ISSN 2211-1247 Publisher: Cell Press DOI: 10.1016/j.celrep.2016.12.054 Understanding the interplay between CpG island-associated gene promoters and H3K4 methylation Author(s): Amy L. Hughes, Jessica R. Kelley, Robert J. Klose Published in: Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, Issue 1863/8, 2020, Page(s) 194567, ISSN 1874-9399 Publisher: Elsevier BV DOI: 10.1016/j.bbagrm.2020.194567 RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes Author(s): Nathan R Rose, Hamish W King, Neil P Blackledge, Nadezda A Fursova, Katherine JI Ember, Roman Fischer, Benedikt M Kessler, Robert J Klose Published in: eLife, Issue 5, 2016, ISSN 2050-084X Publisher: eLife Sciences Publications DOI: 10.7554/eLife.18591 Polycomb repressive complex 1 shapes the nucleosome landscape but not accessibility at target genes Author(s): Hamish W. King, Nadezda A. Fursova, Neil P. Blackledge, Robert J. Klose Published in: Genome Research, Issue 28/10, 2018, Page(s) 1494-1507, ISSN 1088-9051 Publisher: Cold Spring Harbor Laboratory Press DOI: 10.1101/gr.237180.118 Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression Author(s): Nadezda A. Fursova, Neil P. Blackledge, Manabu Nakayama, Shinsuke Ito, Yoko Koseki, Anca M. Farcas, Hamish W. King, Haruhiko Koseki, Robert J. Klose Published in: Molecular Cell, Issue 74/5, 2019, Page(s) 1020-1036.e8, ISSN 1097-2765 Publisher: Cell Press DOI: 10.1016/j.molcel.2019.03.024 Cohesin Disrupts Polycomb-Dependent Chromosome Interactions in Embryonic Stem Cells Author(s): James D.P. Rhodes, Angelika Feldmann, Benjamín Hernández-Rodríguez, Noelia Díaz, Jill M. Brown, Nadezda A. Fursova, Neil P. Blackledge, Praveen Prathapan, Paula Dobrinic, Miles K. Huseyin, Aleksander Szczurek, Kai Kruse, Kim A. Nasmyth, Veronica J. Buckle, Juan M. Vaquerizas, Robert J. Klose Published in: Cell Reports, Issue 30/3, 2020, Page(s) 820-835.e10, ISSN 2211-1247 Publisher: Cell Press DOI: 10.1016/j.celrep.2019.12.057 The pioneer factor OCT4 requires the chromatin remodeller BRG1 to support gene regulatory element function in mouse embryonic stem cells Author(s): Hamish W King, Robert J Klose Published in: eLife, Issue 6, 2017, ISSN 2050-084X Publisher: eLife Sciences Publications DOI: 10.7554/elife.22631 Cohesin Disrupts Polycomb-Dependent Chromosome Interactions in Embryonic Stem Cells Author(s): James D.P. Rhodes, Angelika Feldmann, Benjamín Hernández-Rodríguez, Noelia Díaz, Jill M. Brown, Nadezda A. Fursova, Neil P. Blackledge, Praveen Prathapan, Paula Dobrinic, Miles K. Huseyin, Aleksander Szczurek, Kai Kruse, Kim A. Nasmyth, Veronica J. Buckle, Juan M. Vaquerizas, Robert J. Klose Published in: Cell Reports, Issue 30/3, 2020, Page(s) 820-835.e10, ISSN 2211-1247 Publisher: Cell Press DOI: 10.1016/j.celrep.2019.12.057 PRC1 drives Polycomb-mediated gene repression by controlling transcription initiation and burst frequency Author(s): Paula Dobrinić, Aleksander T. Szczurek, Robert J. Klose Published in: Nature Structural & Molecular Biology, Issue 28/10, 2021, Page(s) 811-824, ISSN 1545-9993 Publisher: Nature Publishing Group DOI: 10.1038/s41594-021-00661-y PRC1 Catalytic Activity Is Central to Polycomb System Function Author(s): Neil P. Blackledge, Nadezda A. Fursova, Jessica R. Kelley, Miles K. Huseyin, Angelika Feldmann, Robert J. Klose Published in: Molecular Cell, Issue 77/4, 2020, Page(s) 857-874.e9, ISSN 1097-2765 Publisher: Cell Press DOI: 10.1016/j.molcel.2019.12.001 Other (1) Cohesin disrupts polycomb-dependent chromosome interactions Author(s): JDP Rhodes, A Feldmann, B Hernández-Rodríguez, N Díaz, JM Brown, NA Fursova, NP Blackledge, P Prathapan, P Dobrinic, M Huseyin, A Szczurek, K Kruse, KA Nasmyth, VJ Buckle, JM Vaquerizas, RJ Klose Published in: BioRxiv, 2019 Publisher: Cold Spring Harbor Laboratory DOI: 10.1101/593970 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
