Publicaciones Peer reviewed articles (24) Identifying proteins bound to native mitotic ESC chromosomes reveals chromatin repressors are important for compaction Autores: Dounia Djeghloul, Bhavik Patel, Holger Kramer, Andrew Dimond, Chad Whilding, Karen Brown, Anne-Céline Kohler, Amelie Feytout, Nicolas Veland, James Elliott, Tanmay A. M. Bharat, Abul K. Tarafder, Jan Löwe, Bee L. Ng, Ya Guo, Jacky Guy, Miles K. Huseyin, Robert J. Klose, Matthias Merkenschlager, Amanda G. Fisher Publicado en: Nature Communications, Edición 11/1, 2020, ISSN 2041-1723 Editor: Nature Publishing Group DOI: 10.1038/s41467-020-17823-z The SET1 Complex Selects Actively Transcribed Target Genes via Multivalent Interaction with CpG Island Chromatin Autores: David A. Brown, Vincenzo Di Cerbo, Angelika Feldmann, Jaewoo Ahn, Shinsuke Ito, Neil P. Blackledge, Manabu Nakayama, Michael McClellan, Emilia Dimitrova, Anne H. Turberfield, Hannah K. Long, Hamish W. King, Skirmantas Kriaucionis, Lothar Schermelleh, Tatiana G. Kutateladze, Haruhiko Koseki, Robert J. Klose Publicado en: Cell Reports, Edición 20/10, 2017, Página(s) 2313-2327, ISSN 2211-1247 Editor: Cell Press DOI: 10.1016/j.celrep.2017.08.030 ATACing DNA Methylation during Differentiation Autores: Skirmantas Kriaucionis, Robert J. Klose Publicado en: Molecular Cell, Edición 77/6, 2020, Página(s) 1159-1161, ISSN 1097-2765 Editor: Cell Press DOI: 10.1016/j.molcel.2020.02.026 RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes Autores: Nathan R Rose, Hamish W King, Neil P Blackledge, Nadezda A Fursova, Katherine JI Ember, Roman Fischer, Benedikt M Kessler, Robert J Klose Publicado en: eLife, Edición 5, 2016, ISSN 2050-084X Editor: eLife Sciences Publications DOI: 10.7554/elife.18591 KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity Autores: Anne H Turberfield, Takashi Kondo, Manabu Nakayama, Yoko Koseki, Hamish W King, Haruhiko Koseki, Robert J Klose Publicado en: Nucleic Acids Research, Edición 47/17, 2019, Página(s) 9005-9023, ISSN 0305-1048 Editor: Oxford University Press DOI: 10.1093/nar/gkz607 BAP1 constrains pervasive H2AK119ub1 to control the transcriptional potential of the genome Autores: Nadezda A. Fursova, Anne H. Turberfield, Neil P. Blackledge, Emma L. Findlater, Anna Lastuvkova, Miles K. Huseyin, Paula Dobrinić, Robert J. Klose Publicado en: Genes & Development, Edición 35/9-10, 2021, Página(s) 749-770, ISSN 0890-9369 Editor: Cold Spring Harbor Laboratory Press DOI: 10.1101/gad.347005.120 PRC1 Catalytic Activity Is Central to Polycomb System Function Autores: Neil P. Blackledge, Nadezda A. Fursova, Jessica R. Kelley, Miles K. Huseyin, Angelika Feldmann, Robert J. Klose Publicado en: Molecular Cell, Edición 77/4, 2020, Página(s) 857-874.e9, ISSN 1097-2765 Editor: Cell Press DOI: 10.1016/j.molcel.2019.12.001 CDK-Mediator and FBXL19 prime developmental genes for activation by promoting atypical regulatory interactions Autores: Angelika Feldmann, Emilia Dimitrova, Alexander Kenney, Anna Lastuvkova, Robert J Klose Publicado en: Nucleic Acids Research, Edición 48/6, 2020, Página(s) 2942-2955, ISSN 0305-1048 Editor: Oxford University Press DOI: 10.1093/nar/gkaa064 Getting under the skin of Polycomb-dependent gene regulation Autores: Neil P. Blackledge, Robert J. Klose Publicado en: Genes & Development, Edición 35/5-6, 2021, Página(s) 301-303, ISSN 0890-9369 Editor: Cold Spring Harbor Laboratory Press DOI: 10.1101/gad.348257.121 Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression Autores: Nadezda A. Fursova, Neil P. Blackledge, Manabu Nakayama, Shinsuke Ito, Yoko Koseki, Anca M. Farcas, Hamish W. King, Haruhiko Koseki, Robert J. Klose Publicado en: Molecular Cell, Edición 74/5, 2019, Página(s) 1020-1036.e8, ISSN 1097-2765 Editor: Cell Press DOI: 10.1016/j.molcel.2019.03.024 FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment Autores: Emilia Dimitrova, Takashi Kondo, Angelika Feldmann, Manabu Nakayama, Yoko Koseki, Rebecca Konietzny, Benedikt M Kessler, Haruhiko Koseki, Robert J Klose Publicado en: eLife, Edición 7, 2018, ISSN 2050-084X Editor: eLife Sciences Publications DOI: 10.7554/elife.37084 Distinct contributions of DNA methylation and histone acetylation to the genomic occupancy of transcription factors Autores: Martin Cusack, Hamish W. King, Paolo Spingardi, Benedikt M. Kessler, Robert J. Klose, Skirmantas Kriaucionis Publicado en: Genome Research, Edición 30/10, 2020, Página(s) 1393-1406, ISSN 1088-9051 Editor: Cold Spring Harbor Laboratory Press DOI: 10.1101/gr.257576.119 Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy Autores: Miles K. Huseyin, Robert J. Klose Publicado en: Nature Communications, Edición 12/1, 2021, ISSN 2041-1723 Editor: Nature Publishing Group DOI: 10.1038/s41467-021-21130-6 Polycomb repressive complex 1 shapes the nucleosome landscape but not accessibility at target genes Autores: Hamish W. King, Nadezda A. Fursova, Neil P. Blackledge, Robert J. Klose Publicado en: Genome Research, Edición 28/10, 2018, Página(s) 1494-1507, ISSN 1088-9051 Editor: Cold Spring Harbor Laboratory Press DOI: 10.1101/gr.237180.118 MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia Autores: Jon Kerry, Laura Godfrey, Emmanouela Repapi, Marta Tapia, Neil P. Blackledge, Helen Ma, Erica Ballabio, Sorcha O’Byrne, Frida Ponthan, Olaf Heidenreich, Anindita Roy, Irene Roberts, Marina Konopleva, Robert J. Klose, Huimin Geng, Thomas A. Milne Publicado en: Cell Reports, Edición 18/2, 2017, Página(s) 482-495, ISSN 2211-1247 Editor: Cell Press DOI: 10.1016/j.celrep.2016.12.054 Understanding the interplay between CpG island-associated gene promoters and H3K4 methylation Autores: Amy L. Hughes, Jessica R. Kelley, Robert J. Klose Publicado en: Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, Edición 1863/8, 2020, Página(s) 194567, ISSN 1874-9399 Editor: Elsevier BV DOI: 10.1016/j.bbagrm.2020.194567 RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes Autores: Nathan R Rose, Hamish W King, Neil P Blackledge, Nadezda A Fursova, Katherine JI Ember, Roman Fischer, Benedikt M Kessler, Robert J Klose Publicado en: eLife, Edición 5, 2016, ISSN 2050-084X Editor: eLife Sciences Publications DOI: 10.7554/eLife.18591 Polycomb repressive complex 1 shapes the nucleosome landscape but not accessibility at target genes Autores: Hamish W. King, Nadezda A. Fursova, Neil P. Blackledge, Robert J. Klose Publicado en: Genome Research, Edición 28/10, 2018, Página(s) 1494-1507, ISSN 1088-9051 Editor: Cold Spring Harbor Laboratory Press DOI: 10.1101/gr.237180.118 Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression Autores: Nadezda A. Fursova, Neil P. Blackledge, Manabu Nakayama, Shinsuke Ito, Yoko Koseki, Anca M. Farcas, Hamish W. King, Haruhiko Koseki, Robert J. Klose Publicado en: Molecular Cell, Edición 74/5, 2019, Página(s) 1020-1036.e8, ISSN 1097-2765 Editor: Cell Press DOI: 10.1016/j.molcel.2019.03.024 Cohesin Disrupts Polycomb-Dependent Chromosome Interactions in Embryonic Stem Cells Autores: James D.P. Rhodes, Angelika Feldmann, Benjamín Hernández-Rodríguez, Noelia Díaz, Jill M. Brown, Nadezda A. Fursova, Neil P. Blackledge, Praveen Prathapan, Paula Dobrinic, Miles K. Huseyin, Aleksander Szczurek, Kai Kruse, Kim A. Nasmyth, Veronica J. Buckle, Juan M. Vaquerizas, Robert J. Klose Publicado en: Cell Reports, Edición 30/3, 2020, Página(s) 820-835.e10, ISSN 2211-1247 Editor: Cell Press DOI: 10.1016/j.celrep.2019.12.057 The pioneer factor OCT4 requires the chromatin remodeller BRG1 to support gene regulatory element function in mouse embryonic stem cells Autores: Hamish W King, Robert J Klose Publicado en: eLife, Edición 6, 2017, ISSN 2050-084X Editor: eLife Sciences Publications DOI: 10.7554/elife.22631 Cohesin Disrupts Polycomb-Dependent Chromosome Interactions in Embryonic Stem Cells Autores: James D.P. Rhodes, Angelika Feldmann, Benjamín Hernández-Rodríguez, Noelia Díaz, Jill M. Brown, Nadezda A. Fursova, Neil P. Blackledge, Praveen Prathapan, Paula Dobrinic, Miles K. Huseyin, Aleksander Szczurek, Kai Kruse, Kim A. Nasmyth, Veronica J. Buckle, Juan M. Vaquerizas, Robert J. Klose Publicado en: Cell Reports, Edición 30/3, 2020, Página(s) 820-835.e10, ISSN 2211-1247 Editor: Cell Press DOI: 10.1016/j.celrep.2019.12.057 PRC1 drives Polycomb-mediated gene repression by controlling transcription initiation and burst frequency Autores: Paula Dobrinić, Aleksander T. Szczurek, Robert J. Klose Publicado en: Nature Structural & Molecular Biology, Edición 28/10, 2021, Página(s) 811-824, ISSN 1545-9993 Editor: Nature Publishing Group DOI: 10.1038/s41594-021-00661-y PRC1 Catalytic Activity Is Central to Polycomb System Function Autores: Neil P. Blackledge, Nadezda A. Fursova, Jessica R. Kelley, Miles K. Huseyin, Angelika Feldmann, Robert J. Klose Publicado en: Molecular Cell, Edición 77/4, 2020, Página(s) 857-874.e9, ISSN 1097-2765 Editor: Cell Press DOI: 10.1016/j.molcel.2019.12.001 Other (1) Cohesin disrupts polycomb-dependent chromosome interactions Autores: JDP Rhodes, A Feldmann, B Hernández-Rodríguez, N Díaz, JM Brown, NA Fursova, NP Blackledge, P Prathapan, P Dobrinic, M Huseyin, A Szczurek, K Kruse, KA Nasmyth, VJ Buckle, JM Vaquerizas, RJ Klose Publicado en: BioRxiv, 2019 Editor: Cold Spring Harbor Laboratory DOI: 10.1101/593970 Buscando datos de OpenAIRE... Se ha producido un error en la búsqueda de datos de OpenAIRE No hay resultados disponibles
