Mechanism of centriole inheritance and maintenance

Informazioni relative al progetto

CentrioleBirthDeath

ID dell’accordo di sovvenzione: 683258

DOI 10.3030/683258

Progetto chiuso

Data della firma CE 22 Luglio 2016

Data di avvio 1 Gennaio 2017

Data di completamento 30 Giugno 2023

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 2 000 000,00

Contributo UE € 2 000 000,00

Coordinato da

FUNDACAO CALOUSTE GULBENKIAN
Portugal

Pubblicazioni

Peer reviewed articles (8)

The 3D architecture and molecular foundations of de novo centriole assembly via bicentrioles

Autori: Sónia Gomes Pereira, Ana Laura Sousa, Catarina Nabais, Tiago Paixão, Alexander J. Holmes, Martin Schorb, Gohta Goshima, Erin M. Tranfield, Jörg D. Becker, Mónica Bettencourt-Dias
Pubblicato in: Current Biology, 2021, ISSN 0960-9822
Editore: Cell Press
DOI: 10.1016/j.cub.2021.07.063

Plk4 triggers autonomous de novo centriole biogenesis and maturation

Autori: Catarina Nabais, Delphine Pessoa, Jorge de-Carvalho, Thomas van Zanten, Paulo Duarte, Satyajit Mayor, Jorge Carneiro, Ivo A Telley, Mónica Bettencourt-Dias
Pubblicato in: The Journal of Cell Biology, 2021, ISSN 0021-9525
Editore: Rockefeller University Press
DOI: 10.1083/jcb.202008090

Pericentrin-mediated SAS-6 recruitment promotes centriole assembly

Autori: Daisuke Ito, Sihem Zitouni, Swadhin Chandra Jana, Paulo Duarte, Jaroslaw Surkont, Zita Carvalho-Santos, José B Pereira-Leal, Miguel Godinho Ferreira, Mónica Bettencourt-Dias
Pubblicato in: eLife, Numero 8, 2019, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.41418

PLK4 is a microtubule-associated protein that self-assembles promoting de novo MTOC formation

Autori: Susana Montenegro Gouveia, Sihem Zitouni, Dong Kong, Paulo Duarte, Beatriz Ferreira Gomes, Ana Laura Sousa, Erin M. Tranfield, Anthony Hyman, Jadranka Loncarek, Monica Bettencourt-Dias
Pubblicato in: Journal of Cell Science, Numero 132/4, 2018, Pagina/e jcs219501, ISSN 0021-9533
Editore: The Company of Biologists Ltd.
DOI: 10.1242/jcs.219501

Differential regulation of transition zone and centriole proteins contributes to ciliary base diversity

Autori: Swadhin Chandra Jana, Susana Mendonça, Pedro Machado, Sascha Werner, Jaqueline Rocha, António Pereira, Helder Maiato, Mónica Bettencourt-Dias
Pubblicato in: Nature Cell Biology, Numero 20/8, 2018, Pagina/e 928-941, ISSN 1465-7392
Editore: Nature Publishing Group
DOI: 10.1038/s41556-018-0132-1

Noncanonical Biogenesis of Centrioles and Basal Bodies

Autori: Catarina Nabais, Sónia Gomes Pereira, Mónica Bettencourt-Dias
Pubblicato in: Cold Spring Harbor Symposia on Quantitative Biology, Numero 82, 2017, Pagina/e 123-135, ISSN 0091-7451
Editore: Cold Spring Harbor Laboratory Press
DOI: 10.1101/sqb.2017.82.034694

Maintaining centrosomes and cilia

Autori: Sascha Werner, Ana Pimenta-Marques, Mónica Bettencourt-Dias
Pubblicato in: Journal of Cell Science, Numero 130/22, 2017, Pagina/e 3789-3800, ISSN 0021-9533
Editore: The Company of Biologists Ltd.
DOI: 10.1242/jcs.203505

A first-takes-all model of centriole copy number control based on cartwheel elongation

Autori: Marco António Dias Louro, Mónica Bettencourt-Dias, Jorge Carneiro
Pubblicato in: PLOS Computational Biology, Numero 17/5, 2021, Pagina/e e1008359, ISSN 1553-7358
Editore: Plos
DOI: 10.1371/journal.pcbi.1008359

Non-peer reviewed articles (4)

Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase

Autori: Ana Pimenta-Marques, Tania Perestrelo, Patricia Rodrigues, Paulo Duarte, Mariana Lince-Faria, Mónica Bettencourt-Dias
Pubblicato in: bioRxiv, 2022, ISSN 2692-8205
Editore: bioRxiv
DOI: 10.1101/2022.04.06.487296

McIdas localizes at centrioles and controls centriole numbers through PLK4-dependent phosphorylation

Autori: Marina Arbi, Margarita Skamnelou, Spyridoula Bournaka, Sihem Zitouni, Stavroula Tsaridou, Ozge Karayel, Catherine G. Vasilopoulou, Aikaterini C. Tsika, Nikolaos N. Giakoumakis, Georgios A. Spyroulias, Matthias Mann, Mónica Bettencourt-Dias, Stavros Taraviras, Zoi Lygerou
Pubblicato in: Biorxiv, 2022, ISSN 2692-8205
Editore: bioRxiv
DOI: 10.1101/2022.09.30.510086

IFT88 transports Gucy2d, a guanylyl cyclase, to maintain sensory cilia function in Drosophila

Autori: Sascha Werner, Sihem Zitouni, Pilar Okenve-Ramos, Susana Mendonça, Anje Sporbert, Christian Spalthoff, Martin C. Göpfert, Swadhin Chandra Jana, Mónica Bettencourt-Dias
Pubblicato in: bioRxiv, 2020, ISSN 2692-8205
Editore: bioRxiv
DOI: 10.1101/2020.12.15.417840

Pericentriolar Material

Autori: Ana Rita Pimenta-Marques, Monica Bettencourt-Dias
Pubblicato in: Current Biology, Numero 33/12, 2020, Pagina/e R687-R689, ISSN 0960-9822
Editore: Cell Press
DOI: 10.1016/j.cub.2020.04.064