Folate-Target Nanodevices To Activated Macrophages For Rheumatoid Arthritis

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Design of the logo, Launch of website, Twitter, Facebook, LinkedIn, Google Plus
Plan and formal distribution of essential internal procedures and tools
Exploitation activity - yearly report 1 in knowledge subjected of protection
Individualized press release for every partner
Exploitation activity - yearly report 3 in knowledge subjected of protection
Exploitation activity - yearly report 2 in knowledge subjected of protection

Dissemination plan revised

Publications

The role of phagocytic cells in acute respiratory distress syndrome

Auteurs: Petre, A., A. Ohradanova-Repic, K. Krenn, R. Ullrich, K. Markstaller, and H. Stockinger
Publié dans: 5th European congress of immunology Amsterdam 2018 : September 2 - 5 : Abstract Book, 2018, Page(s) 151
Éditeur: European Congress of Immunology

The purinergic pathway activated by the proinflammatory stimuli endows M-CSF-dependent folate receptor ß (FRß)+ macrophages with potent immunosuppressive capacity

Auteurs: Ohradanova-Repic, A., C. Machacek, C. Charvet, F. Lager, D. Le Roux, R. Platzer, V. Leksa, G. Mitulovic, T. R. Burkard, G. J. Zlabinger, M. B. Fischer, G. Renault, S. Blüml, A. Cavaco-Paulo, J. B. Huppa, G. Bismuth, and H. Stockinger
Publié dans: Meeting Book of the Annual Meeting of the Austrian Society for Allergology and Immunology 2018, 2018, Page(s) 26
Éditeur: Annual Meeting of the Austrian Society for Allergology and Immunology 2018

Folate-targeted liposomes for rheumatoid arthritis therapy

Auteurs: Nogueira, Eugénia Sofia Costa; Cavaco-Paulo, Artur
Publié dans: Abstract Book of the XII Spanish-Portuguese Conference on Controlled Drug Delivery - Tailoring drug delivery systems to the patients’ needs, 2018, Page(s) 43
Éditeur: The Spanish Portuguese Local Chapter of the Controlled Release Society (SPLC-CRS)

Effect of sucrose in freeze-dried liposomes encapsulating drugs

Auteurs: Diana Guimarães, Eugénia Nogueira, Artur Cavaco-Paulo
Publié dans: Abstract Book of the XII Spanish-Portuguese Conference on Controlled Drug Delivery - Tailoring drug delivery systems to the patients’ needs, 2018, Page(s) 80
Éditeur: The Spanish Portuguese Local Chapter of the Controlled Release Society (SPLC-CRS)

Folic acid-tagged protein nanoemulsions with controllable size for cancer therapy

Auteurs: Loureiro, Ana Isabel Sá; Cavaco-Paulo, Artur
Publié dans: Abstract Book of the XII Spanish-Portuguese Conference on Controlled Drug Delivery - Tailoring drug delivery systems to the patients’ needs, Numéro 2, 2018, Page(s) 105
Éditeur: The Spanish Portuguese Local Chapter of the Controlled Release Society (SPLC-CRS)

Role of Metabolism in Regulating Immune Cell Fate Decisions

Auteurs: Anna Ohradanova-Repic, Marianne Boes, Hannes Stockinger (Eds.)
Publié dans: Role of Metabolism in Regulating Immune Cell Fate Decisions, 2020, ISBN 9782889637218
Éditeur: Frontiers Media
DOI: 10.3389/978-2-88963-721-8

Quantification of drugs encapsulated in liposomes by 1H NMR

Auteurs: Diana Guimarães, Jennifer Noro, Ana Loureiro, Artur Cavaco-Paulo, Eugénia Nogueira
Publié dans: Colloids and Surfaces B: Biointerfaces, Numéro 179, 2019, Page(s) 414-420, ISSN 0927-7765
Éditeur: Elsevier BV
DOI: 10.1016/j.colsurfb.2019.03.039

PTS micelles for the delivery of hydrophobic methotrexate

Auteurs: Patrícia Cerqueira, Jennifer Noro, Sofia Moura, Diana Guimarães, Carla Silva, Artur Cavaco-Paulo, Ana Loureiro
Publié dans: International Journal of Pharmaceutics, Numéro 566, 2019, Page(s) 282-290, ISSN 0378-5173
Éditeur: Elsevier BV
DOI: 10.1016/j.ijpharm.2019.05.049

Editorial: Role of Metabolism in Regulating Immune Cell Fate Decisions

Auteurs: Anna Ohradanova-Repic; Marianne Boes; Hannes Stockinger
Publié dans: Frontiers in Immunology, Numéro 1, 2019, ISSN 1664-3224
Éditeur: Frontiers Media
DOI: 10.3389/fimmu.2020.00527

Protective Effect of Saccharides on Freeze-Dried Liposomes Encapsulating Drugs

Auteurs: Diana Guimarães, Jennifer Noro, Carla Silva, Artur Cavaco-Paulo, Eugénia Nogueira
Publié dans: Frontiers in Bioengineering and Biotechnology, Numéro 7, 2019, ISSN 2296-4185
Éditeur: Frontiers Media
DOI: 10.3389/fbioe.2019.00424

Glutathione from recovered glucose as ingredient in antioxidant nanocapsules for triggered flavor delivery

Auteurs: Claudia Tallian, Vanessa Rumpler, Lukas Skopek, Hannes Russmayer, Matthias G. Steiger, Robert Vielnascher, Simone Weinberger, Alessandro Pellis, Sara Vecchiato, Georg M. Guebitz
Publié dans: Journal of Materials Chemistry B, Numéro 7/25, 2019, Page(s) 3958-3969, ISSN 2050-7518
Éditeur: Royal Society of Chemistry
DOI: 10.1039/c9tb00473d

Increased Encapsulation Efficiency of Methotrexate in Liposomes for Rheumatoid Arthritis Therapy

Auteurs: Diana Guimarães, Jennifer Noro, Ana Loureiro, Franck Lager, Gilles Renault, Artur Cavaco-Paulo and Eugénia Nogueira
Publié dans: Biomedicines, 2020, ISSN 2227-9059
Éditeur: MDPI
DOI: 10.3390/biomedicines8120630

Internalization of Methotrexate Conjugates by Folate Receptor-α

Auteurs: Eugénia Nogueira, Marisa P. Sárria, Nuno G. Azoia, Egipto Antunes, Ana Loureiro, Diana Guimarães, Jennifer Noro, Alexandra Rollett, Georg Guebitz, Artur Cavaco-Paulo
Publié dans: Biochemistry, Numéro 57/49, 2018, Page(s) 6780-6786, ISSN 0006-2960
Éditeur: American Chemical Society
DOI: 10.1021/acs.biochem.8b00607

Extracellular Purine Metabolism Is the Switchboard of Immunosuppressive Macrophages and a Novel Target to Treat Diseases With Macrophage Imbalances

Auteurs: Anna Ohradanova-Repic, Christian Machacek, Celine Charvet, Franck Lager, Delphine Le Roux, René Platzer, Vladimir Leksa, Goran Mitulovic, Thomas R. Burkard, Gerhard J. Zlabinger, Michael B. Fischer, Vincent Feuillet, Gilles Renault, Stephan Blüml, Miroslav Benko, Miloslav Suchanek, Johannes B. Huppa, Takami Matsuyama, Artur Cavaco-Paulo, Georges Bismuth, Hannes Stockinger
Publié dans: Frontiers in Immunology, Numéro 9, 2018, ISSN 1664-3224
Éditeur: Frontiers
DOI: 10.3389/fimmu.2018.00852

Fasting metabolism modulates the interleukin-12/interleukin-10 cytokine axis

Auteurs: Johannes J. Kovarik, Elisabeth Kernbauer, Markus A. Hölzl, Johannes Hofer, Guido A. Gualdoni, Klaus G. Schmetterer, Fitore Miftari, Yury Sobanov, Anastasia Meshcheryakova, Diana Mechtcheriakova, Nadine Witzeneder, Georg Greiner, Anna Ohradanova-Repic, Petra Waidhofer-Söllner, Marcus D. Säemann, Thomas Decker, Gerhard J. Zlabinger
Publié dans: PLOS ONE, Numéro 12/7, 2017, Page(s) e0180900, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0180900

Fab antibody fragment-functionalized liposomes for specific targeting of antigen-positive cells

Auteurs: Anna Ohradanova-Repic, Eugénia Nogueira, Ingrid Hartl, Andreia C. Gomes, Ana Preto, Eva Steinhuber, Vanessa Mühlgrabner, Marko Repic, Mario Kuttke, Alexander Zwirzitz, Marek Prouza, Miloslav Suchanek, Gordana Wozniak-Knopp, Vaclav Horejsi, Gernot Schabbauer, Artur Cavaco-Paulo, Hannes Stockinger
Publié dans: Nanomedicine: Nanotechnology, Biology and Medicine, Numéro 14/1, 2018, Page(s) 123-130, ISSN 1549-9634
Éditeur: Elsevier BV
DOI: 10.1016/j.nano.2017.09.003

Starved viable but non-culturable (VBNC) Legionella strains can infect and replicate in amoebae and human macrophages

Auteurs: Elisabeth Dietersdorfer, Alexander Kirschner, Barbara Schrammel, Anna Ohradanova-Repic, Hannes Stockinger, Regina Sommer, Julia Walochnik, Sílvia Cervero-Aragó
Publié dans: Water Research, Numéro 141, 2018, Page(s) 428-438, ISSN 0043-1354
Éditeur: Elsevier BV
DOI: 10.1016/j.watres.2018.01.058

Lactoferrin is a natural inhibitor of plasminogen activation

Auteurs: Alexander Zwirzitz, Michael Reiter, Rostislav Skrabana, Anna Ohradanova-Repic, Otto Majdic, Marianna Gutekova, Ondrej Cehlar, Eva Petrovčíková, Eva Kutejova, Gerold Stanek, Hannes Stockinger, Vladimir Leksa
Publié dans: Journal of Biological Chemistry, Numéro 293/22, 2018, Page(s) 8600-8613, ISSN 0021-9258
Éditeur: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/jbc.ra118.003145

Absence of Albumin Improves in Vitro Cellular Uptake and Disruption of Poloxamer 407-Based Nanoparticles inside Cancer Cells

Auteurs: Ana Loureiro, Jennifer Noro, Ana S. Abreu, Eugénia Nogueira, Diana Soares da Costa, Carla Silva, Artur Cavaco-Paulo
Publié dans: Molecular Pharmaceutics, Numéro 15/2, 2018, Page(s) 527-535, ISSN 1543-8384
Éditeur: American Chemical Society
DOI: 10.1021/acs.molpharmaceut.7b00893

Structural insights into pH-responsive drug release of self-assembling human serum albumin-silk fibroin nanocapsules

Auteurs: Claudia Tallian, Alexandra Herrero-Rollett, Karina Stadler, Robert Vielnascher, Karin Wieland, Anna M. Weihs, Alessandro Pellis, Andreas H. Teuschl, Bernhard Lendl, Heinz Amenitsch, Georg M. Guebitz
Publié dans: European Journal of Pharmaceutics and Biopharmaceutics, Numéro 133, 2018, Page(s) 176-187, ISSN 0939-6411
Éditeur: Elsevier BV
DOI: 10.1016/j.ejpb.2018.10.002

Dynamic Interaction- and Phospho-Proteomics Reveal Lck as a Major Signaling Hub of CD147 in T Cells

Auteurs: Verena Supper, Ingrid Hartl, Cyril Boulègue, Anna Ohradanova-Repic, Hannes Stockinger
Publié dans: The Journal of Immunology, Numéro 198/6, 2017, Page(s) 2468-2478, ISSN 0022-1767
Éditeur: American Association of Immunologists
DOI: 10.4049/jimmunol.1600355

The mannose 6‐phosphate/insulin‐like growth factor 2 receptor mediates plasminogen‐induced efferocytosis

Auteurs: Ohradanova‐Repic, Anna; Machacek, Christian; Donner, Clemens; Mühlgrabner, Vanessa; Petrovčíková, Eva; Zahradníková, Alexandra; Vičíková, Kristína; Hořejší, Václav; Stockinger, Hannes; Leksa, Vladimir
Publié dans: Journal of Leukocyte Biology, Numéro 1, 2019, ISSN 0165-2478
Éditeur: Elsevier BV
DOI: 10.1002/jlb.1ab0417-160rr

Poloxamer 407 based-nanoparticles for controlled release of methotrexate

Auteurs: Sofia Moura, Jennifer Noro, Patrícia Cerqueira, Carla Silva, Artur Cavaco-Paulo, Ana Loureiro
Publié dans: International Journal of Pharmaceutics, Numéro 575, 2020, Page(s) 118924, ISSN 0378-5173
Éditeur: Elsevier BV
DOI: 10.1016/j.ijpharm.2019.118924

Droits de propriété intellectuelle

METHOD FOR PRODUCTION OF LIPOSOMES

Numéro de demande/publication: 20 20054346
Date: 2020-05-07
Demandeur(s): SOLFARCOS - SOLUÇÕES FARMACÊUTICAS E COSMÉTICAS LDA

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