Folate-Target Nanodevices To Activated Macrophages For Rheumatoid Arthritis

Risultati finali

Design of the logo, Launch of website, Twitter, Facebook, LinkedIn, Google Plus
Plan and formal distribution of essential internal procedures and tools
Exploitation activity - yearly report 1 in knowledge subjected of protection
Individualized press release for every partner
Exploitation activity - yearly report 3 in knowledge subjected of protection
Exploitation activity - yearly report 2 in knowledge subjected of protection

Dissemination plan revised

Pubblicazioni

The role of phagocytic cells in acute respiratory distress syndrome

Autori: Petre, A., A. Ohradanova-Repic, K. Krenn, R. Ullrich, K. Markstaller, and H. Stockinger
Pubblicato in: 5th European congress of immunology Amsterdam 2018 : September 2 - 5 : Abstract Book, 2018, Pagina/e 151
Editore: European Congress of Immunology

The purinergic pathway activated by the proinflammatory stimuli endows M-CSF-dependent folate receptor ß (FRß)+ macrophages with potent immunosuppressive capacity

Autori: Ohradanova-Repic, A., C. Machacek, C. Charvet, F. Lager, D. Le Roux, R. Platzer, V. Leksa, G. Mitulovic, T. R. Burkard, G. J. Zlabinger, M. B. Fischer, G. Renault, S. Blüml, A. Cavaco-Paulo, J. B. Huppa, G. Bismuth, and H. Stockinger
Pubblicato in: Meeting Book of the Annual Meeting of the Austrian Society for Allergology and Immunology 2018, 2018, Pagina/e 26
Editore: Annual Meeting of the Austrian Society for Allergology and Immunology 2018

Folate-targeted liposomes for rheumatoid arthritis therapy

Autori: Nogueira, Eugénia Sofia Costa; Cavaco-Paulo, Artur
Pubblicato in: Abstract Book of the XII Spanish-Portuguese Conference on Controlled Drug Delivery - Tailoring drug delivery systems to the patients’ needs, 2018, Pagina/e 43
Editore: The Spanish Portuguese Local Chapter of the Controlled Release Society (SPLC-CRS)

Effect of sucrose in freeze-dried liposomes encapsulating drugs

Autori: Diana Guimarães, Eugénia Nogueira, Artur Cavaco-Paulo
Pubblicato in: Abstract Book of the XII Spanish-Portuguese Conference on Controlled Drug Delivery - Tailoring drug delivery systems to the patients’ needs, 2018, Pagina/e 80
Editore: The Spanish Portuguese Local Chapter of the Controlled Release Society (SPLC-CRS)

Folic acid-tagged protein nanoemulsions with controllable size for cancer therapy

Autori: Loureiro, Ana Isabel Sá; Cavaco-Paulo, Artur
Pubblicato in: Abstract Book of the XII Spanish-Portuguese Conference on Controlled Drug Delivery - Tailoring drug delivery systems to the patients’ needs, Numero 2, 2018, Pagina/e 105
Editore: The Spanish Portuguese Local Chapter of the Controlled Release Society (SPLC-CRS)

Role of Metabolism in Regulating Immune Cell Fate Decisions

Autori: Anna Ohradanova-Repic, Marianne Boes, Hannes Stockinger (Eds.)
Pubblicato in: Role of Metabolism in Regulating Immune Cell Fate Decisions, 2020, ISBN 9782889637218
Editore: Frontiers Media
DOI: 10.3389/978-2-88963-721-8

Quantification of drugs encapsulated in liposomes by 1H NMR

Autori: Diana Guimarães, Jennifer Noro, Ana Loureiro, Artur Cavaco-Paulo, Eugénia Nogueira
Pubblicato in: Colloids and Surfaces B: Biointerfaces, Numero 179, 2019, Pagina/e 414-420, ISSN 0927-7765
Editore: Elsevier BV
DOI: 10.1016/j.colsurfb.2019.03.039

PTS micelles for the delivery of hydrophobic methotrexate

Autori: Patrícia Cerqueira, Jennifer Noro, Sofia Moura, Diana Guimarães, Carla Silva, Artur Cavaco-Paulo, Ana Loureiro
Pubblicato in: International Journal of Pharmaceutics, Numero 566, 2019, Pagina/e 282-290, ISSN 0378-5173
Editore: Elsevier BV
DOI: 10.1016/j.ijpharm.2019.05.049

Editorial: Role of Metabolism in Regulating Immune Cell Fate Decisions

Autori: Anna Ohradanova-Repic; Marianne Boes; Hannes Stockinger
Pubblicato in: Frontiers in Immunology, Numero 1, 2019, ISSN 1664-3224
Editore: Frontiers Media
DOI: 10.3389/fimmu.2020.00527

Protective Effect of Saccharides on Freeze-Dried Liposomes Encapsulating Drugs

Autori: Diana Guimarães, Jennifer Noro, Carla Silva, Artur Cavaco-Paulo, Eugénia Nogueira
Pubblicato in: Frontiers in Bioengineering and Biotechnology, Numero 7, 2019, ISSN 2296-4185
Editore: Frontiers Media
DOI: 10.3389/fbioe.2019.00424

Glutathione from recovered glucose as ingredient in antioxidant nanocapsules for triggered flavor delivery

Autori: Claudia Tallian, Vanessa Rumpler, Lukas Skopek, Hannes Russmayer, Matthias G. Steiger, Robert Vielnascher, Simone Weinberger, Alessandro Pellis, Sara Vecchiato, Georg M. Guebitz
Pubblicato in: Journal of Materials Chemistry B, Numero 7/25, 2019, Pagina/e 3958-3969, ISSN 2050-7518
Editore: Royal Society of Chemistry
DOI: 10.1039/c9tb00473d

Increased Encapsulation Efficiency of Methotrexate in Liposomes for Rheumatoid Arthritis Therapy

Autori: Diana Guimarães, Jennifer Noro, Ana Loureiro, Franck Lager, Gilles Renault, Artur Cavaco-Paulo and Eugénia Nogueira
Pubblicato in: Biomedicines, 2020, ISSN 2227-9059
Editore: MDPI
DOI: 10.3390/biomedicines8120630

Internalization of Methotrexate Conjugates by Folate Receptor-α

Autori: Eugénia Nogueira, Marisa P. Sárria, Nuno G. Azoia, Egipto Antunes, Ana Loureiro, Diana Guimarães, Jennifer Noro, Alexandra Rollett, Georg Guebitz, Artur Cavaco-Paulo
Pubblicato in: Biochemistry, Numero 57/49, 2018, Pagina/e 6780-6786, ISSN 0006-2960
Editore: American Chemical Society
DOI: 10.1021/acs.biochem.8b00607

Extracellular Purine Metabolism Is the Switchboard of Immunosuppressive Macrophages and a Novel Target to Treat Diseases With Macrophage Imbalances

Autori: Anna Ohradanova-Repic, Christian Machacek, Celine Charvet, Franck Lager, Delphine Le Roux, René Platzer, Vladimir Leksa, Goran Mitulovic, Thomas R. Burkard, Gerhard J. Zlabinger, Michael B. Fischer, Vincent Feuillet, Gilles Renault, Stephan Blüml, Miroslav Benko, Miloslav Suchanek, Johannes B. Huppa, Takami Matsuyama, Artur Cavaco-Paulo, Georges Bismuth, Hannes Stockinger
Pubblicato in: Frontiers in Immunology, Numero 9, 2018, ISSN 1664-3224
Editore: Frontiers
DOI: 10.3389/fimmu.2018.00852

Fasting metabolism modulates the interleukin-12/interleukin-10 cytokine axis

Autori: Johannes J. Kovarik, Elisabeth Kernbauer, Markus A. Hölzl, Johannes Hofer, Guido A. Gualdoni, Klaus G. Schmetterer, Fitore Miftari, Yury Sobanov, Anastasia Meshcheryakova, Diana Mechtcheriakova, Nadine Witzeneder, Georg Greiner, Anna Ohradanova-Repic, Petra Waidhofer-Söllner, Marcus D. Säemann, Thomas Decker, Gerhard J. Zlabinger
Pubblicato in: PLOS ONE, Numero 12/7, 2017, Pagina/e e0180900, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0180900

Fab antibody fragment-functionalized liposomes for specific targeting of antigen-positive cells

Autori: Anna Ohradanova-Repic, Eugénia Nogueira, Ingrid Hartl, Andreia C. Gomes, Ana Preto, Eva Steinhuber, Vanessa Mühlgrabner, Marko Repic, Mario Kuttke, Alexander Zwirzitz, Marek Prouza, Miloslav Suchanek, Gordana Wozniak-Knopp, Vaclav Horejsi, Gernot Schabbauer, Artur Cavaco-Paulo, Hannes Stockinger
Pubblicato in: Nanomedicine: Nanotechnology, Biology and Medicine, Numero 14/1, 2018, Pagina/e 123-130, ISSN 1549-9634
Editore: Elsevier BV
DOI: 10.1016/j.nano.2017.09.003

Starved viable but non-culturable (VBNC) Legionella strains can infect and replicate in amoebae and human macrophages

Autori: Elisabeth Dietersdorfer, Alexander Kirschner, Barbara Schrammel, Anna Ohradanova-Repic, Hannes Stockinger, Regina Sommer, Julia Walochnik, Sílvia Cervero-Aragó
Pubblicato in: Water Research, Numero 141, 2018, Pagina/e 428-438, ISSN 0043-1354
Editore: Elsevier BV
DOI: 10.1016/j.watres.2018.01.058

Lactoferrin is a natural inhibitor of plasminogen activation

Autori: Alexander Zwirzitz, Michael Reiter, Rostislav Skrabana, Anna Ohradanova-Repic, Otto Majdic, Marianna Gutekova, Ondrej Cehlar, Eva Petrovčíková, Eva Kutejova, Gerold Stanek, Hannes Stockinger, Vladimir Leksa
Pubblicato in: Journal of Biological Chemistry, Numero 293/22, 2018, Pagina/e 8600-8613, ISSN 0021-9258
Editore: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/jbc.ra118.003145

Absence of Albumin Improves in Vitro Cellular Uptake and Disruption of Poloxamer 407-Based Nanoparticles inside Cancer Cells

Autori: Ana Loureiro, Jennifer Noro, Ana S. Abreu, Eugénia Nogueira, Diana Soares da Costa, Carla Silva, Artur Cavaco-Paulo
Pubblicato in: Molecular Pharmaceutics, Numero 15/2, 2018, Pagina/e 527-535, ISSN 1543-8384
Editore: American Chemical Society
DOI: 10.1021/acs.molpharmaceut.7b00893

Structural insights into pH-responsive drug release of self-assembling human serum albumin-silk fibroin nanocapsules

Autori: Claudia Tallian, Alexandra Herrero-Rollett, Karina Stadler, Robert Vielnascher, Karin Wieland, Anna M. Weihs, Alessandro Pellis, Andreas H. Teuschl, Bernhard Lendl, Heinz Amenitsch, Georg M. Guebitz
Pubblicato in: European Journal of Pharmaceutics and Biopharmaceutics, Numero 133, 2018, Pagina/e 176-187, ISSN 0939-6411
Editore: Elsevier BV
DOI: 10.1016/j.ejpb.2018.10.002

Dynamic Interaction- and Phospho-Proteomics Reveal Lck as a Major Signaling Hub of CD147 in T Cells

Autori: Verena Supper, Ingrid Hartl, Cyril Boulègue, Anna Ohradanova-Repic, Hannes Stockinger
Pubblicato in: The Journal of Immunology, Numero 198/6, 2017, Pagina/e 2468-2478, ISSN 0022-1767
Editore: American Association of Immunologists
DOI: 10.4049/jimmunol.1600355

The mannose 6‐phosphate/insulin‐like growth factor 2 receptor mediates plasminogen‐induced efferocytosis

Autori: Ohradanova‐Repic, Anna; Machacek, Christian; Donner, Clemens; Mühlgrabner, Vanessa; Petrovčíková, Eva; Zahradníková, Alexandra; Vičíková, Kristína; Hořejší, Václav; Stockinger, Hannes; Leksa, Vladimir
Pubblicato in: Journal of Leukocyte Biology, Numero 1, 2019, ISSN 0165-2478
Editore: Elsevier BV
DOI: 10.1002/jlb.1ab0417-160rr

Poloxamer 407 based-nanoparticles for controlled release of methotrexate

Autori: Sofia Moura, Jennifer Noro, Patrícia Cerqueira, Carla Silva, Artur Cavaco-Paulo, Ana Loureiro
Pubblicato in: International Journal of Pharmaceutics, Numero 575, 2020, Pagina/e 118924, ISSN 0378-5173
Editore: Elsevier BV
DOI: 10.1016/j.ijpharm.2019.118924

Diritti di proprietà intellettuale

METHOD FOR PRODUCTION OF LIPOSOMES

Numero candidatura/pubblicazione: 20 20054346
Data: 2020-05-07
Candidato/i: SOLFARCOS - SOLUÇÕES FARMACÊUTICAS E COSMÉTICAS LDA

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Pubblicazioni

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