Alzheimer Disease - gut connection | AD-gut | Project | Results | H2020 | CORDIS

Resultado final

Creation of website

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Workshop

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Mid-term press release

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Production of m-MOOCs

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Final press release

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Publicaciones

Native protein hydrogels by dynamic boronic acid chemistry

Autores: Christiane Seidler, David Y.W. Ng, Tanja Weil
Publicado en: Tetrahedron, Edición 73/33, 2017, Página(s) 4979-4987, ISSN 0040-4020
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.tet.2017.06.066

Complementarity of PALM and SOFI for super-resolution live-cell imaging of focal adhesions

Autores: Hendrik Deschout, Tomas Lukes, Azat Sharipov, Daniel Szlag, Lely Feletti, Wim Vandenberg, Peter Dedecker, Johan Hofkens, Marcel Leutenegger, Theo Lasser, Aleksandra Radenovic
Publicado en: Nature Communications, Edición 7, 2016, Página(s) 13693, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/ncomms13693

Spatiotemporally Controlled Release of Rho-Inhibiting C3 Toxin from a Protein-DNA Hybrid Hydrogel for Targeted Inhibition of Osteoclast Formation and Activity

Autores: Jasmina Gačanin, Anna Kovtun, Stephan Fischer, Victoria Schwager, Johanna Quambusch, Seah Ling Kuan, Weina Liu, Felix Boldt, Chuang Li, Zhongqiang Yang, Dongsheng Liu, Yuzhou Wu, Tanja Weil, Holger Barth, Anita Ignatius
Publicado en: Advanced Healthcare Materials, Edición 6/21, 2017, Página(s) 1700392, ISSN 2192-2640
Editor: John Wiley and Sons Ltd
DOI: 10.1002/adhm.201700392

Methyltransferase-Directed Labeling of Biomolecules and its Applications

Autores: Jochem Deen, Charlotte Vranken, Volker Leen, Robert K. Neely, Kris P. F. Janssen, Johan Hofkens
Publicado en: Angewandte Chemie International Edition, Edición 56/19, 2017, Página(s) 5182-5200, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201608625

Reduced Fluorescent Protein Switching Fatigue by Binding-Induced Emissive State Stabilization

Autores: Thijs Roebroek, Sam Duwé, Wim Vandenberg, Peter Dedecker
Publicado en: International Journal of Molecular Sciences, Edición 18/10, 2017, Página(s) 2015, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms18092015

Live-cell monochromatic dual-label sub-diffraction microscopy by mt-pcSOFI

Autores: S. Duwé, W. Vandenberg, P. Dedecker
Publicado en: Chem. Commun., Edición 53/53, 2017, Página(s) 7242-7245, ISSN 1359-7345
Editor: Royal Society of Chemistry
DOI: 10.1039/c7cc02344h

Combined multi-plane phase retrieval and super-resolution optical fluctuation imaging for 4D cell microscopy

Autores: A. Descloux, K. S. Grußmayer, E. Bostan, T. Lukes, A. Bouwens, A. Sharipov, S. Geissbuehler, A.-L. Mahul-Mellier, H. A. Lashuel, M. Leutenegger, T. Lasser
Publicado en: Nature Photonics, Edición 12/3, 2018, Página(s) 165-172, ISSN 1749-4885
Editor: Nature Pub. Group
DOI: 10.1038/s41566-018-0109-4

Optical projection tomography for rapid whole mouse brain imaging

Autores: David Nguyen, Paul J. Marchand, Arielle L. Planchette, Julia Nilsson, Miguel Sison, Jérôme Extermann, Antonio Lopez, Marcin Sylwestrzak, Jessica Sordet-Dessimoz, Anja Schmidt-Christensen, Dan Holmberg, Dimitri Van De Ville, Theo Lasser
Publicado en: Biomedical Optics Express, Edición 8/12, 2017, Página(s) 5637, ISSN 2156-7085
Editor: The Optical Society
DOI: 10.1364/boe.8.005637

Correcting for photodestruction in super-resolution optical fluctuation imaging

Autores: Yves Peeters, Wim Vandenberg, Sam Duwé, Arno Bouwens, Tomáš Lukeš, Cyril Ruckebusch, Theo Lasser, Peter Dedecker
Publicado en: Scientific Reports, Edición 7/1, 2017, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-017-09666-4

Quantifying protein densities on cell membranes using super-resolution optical fluctuation imaging

Autores: Tomáš Lukeš, Daniela Glatzová, Zuzana Kvíčalová, Florian Levet, Aleš Benda, Sebastian Letschert, Markus Sauer, Tomáš Brdička, Theo Lasser, Marek Cebecauer
Publicado en: Nature Communications, Edición 8/1, 2017, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-017-01857-x

Autonomous Ultrafast Self-Healing Hydrogels by pH-Responsive Functional Nanofiber Gelators as Cell Matrices

Autores: Gačanin, J.; Hedrich, J.; Sieste, S.; Glasser, G.; Lieberwirth, I.; Schilling, C.; Fischer, S.; Barth, H.; Knoell, B.; Synatschke, C.; Weil, T.
Publicado en: Advanced Materials, Edición 31, 2019, ISSN 0935-9648
Editor: United Nations Industrial Developement Organization
DOI: 10.1002/adma.201805044

Lectin-Functionalized Composite Hydrogels for “Capture-and-Killing” of Carbapenem-Resistant Pseudomonas aeruginosa

Autores: N. Bodenberger, D. Kubiczek, D. Halbgebauer, V. Rimola, S. Wiese, D. Mayer, A. A. Rodriguez Alfonso, L. Ständker, S. Stenger, F. Rosenau
Publicado en: Biomacromolecules, Edición 19 (7), 2018, Página(s) 2472/2482, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.8b00089

Go with the flow or solitary confinement: a look inside the single-cell toolbox for isolation of rare and uncultured microbes

Autores: G. R. B. Huys, J. Raes
Publicado en: Current Opinion in Microbiology, Edición Vol. 44, 2018, Página(s) 1/8, ISSN 1369-5274
Editor: Elsevier BV
DOI: 10.1016/j.mib.2018.05.002

Orthogonally Stimulated Assembly/Disassembly of Depsi‐peptides by Rational Chemical Design

Autores: M. Pieszka, A. M. Sobota, J. Gačanin, T. Weil, D. Y. W. Ng
Publicado en: ChemBioChem, 2019, ISSN 1439-7633
Editor: Wiley-VCH
DOI: 10.1002/cbic.201800781m

Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota

Autores: T. Harach, N. Marungruang, N. Duthilleul, V. Cheatham, K. D. Mc Coy, G. Frisoni, J. J. Neher, F. Fåk, M. Jucker, T. Lasser, T. Bolmont
Publicado en: Scientific Reports, Edición 7/1, 2017, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/srep41802

Integrated culturing, modeling and transcriptomics uncovers complex interactions and emergent behavior in a three-species synthetic gut community

Autores: K. D’hoe, S. Vet, K. Faust, F. Moens, G. Falony, D. Gonze, V. Llorens-Rico, L. Gelens, J. Danckaert, L. De Vuyst and J. Raes
Publicado en: eLife, 2018, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.37090

Growth of engineered Pseudomonas putida KT2440 on glucose, xylose, and arabinose: Hemicellulose hydrolysates and their major sugars as sustainable carbon sources

Autores: Wang, Y.; Horlamus, F.; Henkel, M.; Kovacic, F.; Schlaefle, S.; Hausmann, R.; Wittgens, A.; Rosenau, F.
Publicado en: GCB Bioenergy, Edición 11, 2019, ISSN 1757-1693
Editor: Wiley-VCH Verlag
DOI: 10.1111/gcbb.12590

Statistical parametric mapping of stimuli evoked changes in total blood flow velocity in the mouse cortex obtained with extended-focus optical coherence microscopy

Autores: Shamaei, Vincent K.; Bouwens, Arno; Szlag, Daniel; Lasser, Theo; Nguyen, David; Extermann, Jérôme; Marchand, Paul J.; Bolmont, Tristan
Publicado en: Biomedical Optics Express, Edición 1, 2017, Página(s) 1-15, ISSN 2156-7085
Editor: The Optical Society
DOI: 10.1364/BOE.8.000001

Single Molecule Localization and Discrimination of DNA–Protein Complexes by Controlled Translocation Through Nanocapillaries

Autores: Bulushev, Roman D.; Davis, Sebastian J.; Sebastian J Maerkl; Marion, Sanjin; Petrova, Ekaterina; Radenovic, Aleksandra
Publicado en: Nano Letters, Edición 1, 2016, Página(s) 7882–7890, ISSN 1530-6984
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.6b04165

Identifying microbial species by single-molecule DNA optical mapping and resampling statistics

Autores: Arno Bouwens, Jochem Deen, Raffaele Vitale, Laurens D’Huys, Vince Goyvaerts, Adrien Descloux, Doortje Borrenberghs, Kristin Grussmayer, Tomas Lukes, Rafael Camacho, Jia Su, Cyril Ruckebusch, Theo Lasser, Dimitri Van De Ville, Johan Hofkens, Aleksandra Radenovic, Kris Pieter Frans Janssen
Publicado en: NAR Genomics and Bioinformatics, Edición 2/1, 2020, ISSN 2631-9268
Editor: Oxford University Press
DOI: 10.1093/nargab/lqz007

Parameter-free image resolution estimation based on decorrelation analysis

Autores: A. Descloux, K. S. Grußmayer, A. Radenovic
Publicado en: Nature Methods, Edición 16/9, 2019, Página(s) 918-924, ISSN 1548-7091
Editor: Nature Publishing Group
DOI: 10.1038/s41592-019-0515-7

Supervised learning to quantify amyloidosis in whole brains of an Alzheimer’s disease mouse model acquired with optical projection tomography

Autores: David Nguyen, Virginie Uhlmann, Arielle L. Planchette, Paul J. Marchand, Dimitri Van De Ville, Theo Lasser, Aleksandra Radenovic
Publicado en: Biomedical Optics Express, Edición 10/6, 2019, Página(s) 3041, ISSN 2156-7085
Editor: The Optical Society
DOI: 10.1364/boe.10.003041

Biomedical Applications of DNA‐Based Hydrogels

Autores: Jasmina Gačanin, Christopher V. Synatschke, Tanja Weil
Publicado en: Advanced Functional Materials, Edición 30/4, 2019, Página(s) 1906253, ISSN 1616-301X
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.201906253

Comparison of Three Xylose Pathways in Pseudomonas putida KT2440 for the Synthesis of Valuable Products

Autores: Isabel Bator, Andreas Wittgens, Frank Rosenau, Till Tiso, Lars M. Blank
Publicado en: Frontiers in Bioengineering and Biotechnology, Edición 7, 2020, ISSN 2296-4185
Editor: Frontiers in Bioengineering and Biotechnology
DOI: 10.3389/fbioe.2019.00480

Fluorescent SAM analogues for methyltransferase based DNA labeling

Autores: Vince Goyvaerts, Sven Van Snick, Laurens D'Huys, Raffaele Vitale, Milena Helmer Lauer, Su Wang, Volker Leen, Wim Dehaen, Johan Hofkens
Publicado en: Chemical Communications, Edición 56/22, 2020, Página(s) 3317-3320, ISSN 1359-7345
Editor: Royal Society of Chemistry
DOI: 10.1039/c9cc08938a

A Cerberus‐Inspired Anti‐Infective Multicomponent Gatekeeper Hydrogel against Infections with the Emerging “Superbug” Yeast Candida auris

Autores: Dennis Kubiczek, Carolin Flaig, Heinz Raber, Steffen Dietz, Ann‐Kathrin Kissmann, Thomas Heerde, Nicholas Bodenberger, Andreas Wittgens, Melaine González‐Garcia, Fan Kang, Octavio L. Franco, Ludger Staendker, Anselmo J. Otero‐González, Paul Walther, Kay E. Gottschalk, Tanja Weil, Frank Rosenau
Publicado en: Macromolecular Bioscience, Edición 20/4, 2020, Página(s) 2000005, ISSN 1616-5187
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.202000005

High-speed multiplane structured illumination microscopy of living cells using an image-splitting prism

Autores: Adrien Descloux, Marcel Müller, Vytautas Navikas, Andreas Markwirth, Robin van den Eynde, Tomas Lukes, Wolfgang Hübner, Theo Lasser, Aleksandra Radenovic, Peter Dedecker, Thomas Huser
Publicado en: Nanophotonics, Edición 9/1, 2019, Página(s) 143-148, ISSN 2192-8614
Editor: De Gruyter
DOI: 10.1515/nanoph-2019-0346

Aptamers as promising agents in diagnostic and therapeutic applications.

Autores: D. Kubiczek, N. Bodenberger, F. Rosenau
Publicado en: Antimicrobial research: Novel bioknowledge and educational programs, 2017
Editor: A. Méndez-Vilas, Ed.

Jelly Bombs–Hydrogels as Weapons against Microorganisms.

Autores: N. Bodenberger, D. Kubiczek, D. Halbgebauer, C. Tanzer, N. Pfahler, F. Rosenau
Publicado en: Antimicrobial research: Novel bioknowledge and educational programs, 2017
Editor: A. Méndez-Vilas, Ed.

Alzheimer Disease - gut connection

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