Alzheimer Disease - gut connection | AD-gut | Project | Results | H2020 | CORDIS

Rezultaty

Creation of website

see WP5 description

Workshop

see WP5 description

Mid-term press release

see WP5 description

Production of m-MOOCs

and at month 48 see WP5 description

Final press release

see WP5 description

Publikacje

Native protein hydrogels by dynamic boronic acid chemistry

Autorzy: Christiane Seidler, David Y.W. Ng, Tanja Weil
Opublikowane w: Tetrahedron, Numer 73/33, 2017, Strona(/y) 4979-4987, ISSN 0040-4020
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.tet.2017.06.066

Complementarity of PALM and SOFI for super-resolution live-cell imaging of focal adhesions

Autorzy: Hendrik Deschout, Tomas Lukes, Azat Sharipov, Daniel Szlag, Lely Feletti, Wim Vandenberg, Peter Dedecker, Johan Hofkens, Marcel Leutenegger, Theo Lasser, Aleksandra Radenovic
Opublikowane w: Nature Communications, Numer 7, 2016, Strona(/y) 13693, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/ncomms13693

Spatiotemporally Controlled Release of Rho-Inhibiting C3 Toxin from a Protein-DNA Hybrid Hydrogel for Targeted Inhibition of Osteoclast Formation and Activity

Autorzy: Jasmina Gačanin, Anna Kovtun, Stephan Fischer, Victoria Schwager, Johanna Quambusch, Seah Ling Kuan, Weina Liu, Felix Boldt, Chuang Li, Zhongqiang Yang, Dongsheng Liu, Yuzhou Wu, Tanja Weil, Holger Barth, Anita Ignatius
Opublikowane w: Advanced Healthcare Materials, Numer 6/21, 2017, Strona(/y) 1700392, ISSN 2192-2640
Wydawca: John Wiley and Sons Ltd
DOI: 10.1002/adhm.201700392

Methyltransferase-Directed Labeling of Biomolecules and its Applications

Autorzy: Jochem Deen, Charlotte Vranken, Volker Leen, Robert K. Neely, Kris P. F. Janssen, Johan Hofkens
Opublikowane w: Angewandte Chemie International Edition, Numer 56/19, 2017, Strona(/y) 5182-5200, ISSN 1433-7851
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201608625

Reduced Fluorescent Protein Switching Fatigue by Binding-Induced Emissive State Stabilization

Autorzy: Thijs Roebroek, Sam Duwé, Wim Vandenberg, Peter Dedecker
Opublikowane w: International Journal of Molecular Sciences, Numer 18/10, 2017, Strona(/y) 2015, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms18092015

Live-cell monochromatic dual-label sub-diffraction microscopy by mt-pcSOFI

Autorzy: S. Duwé, W. Vandenberg, P. Dedecker
Opublikowane w: Chem. Commun., Numer 53/53, 2017, Strona(/y) 7242-7245, ISSN 1359-7345
Wydawca: Royal Society of Chemistry
DOI: 10.1039/c7cc02344h

Combined multi-plane phase retrieval and super-resolution optical fluctuation imaging for 4D cell microscopy

Autorzy: A. Descloux, K. S. Grußmayer, E. Bostan, T. Lukes, A. Bouwens, A. Sharipov, S. Geissbuehler, A.-L. Mahul-Mellier, H. A. Lashuel, M. Leutenegger, T. Lasser
Opublikowane w: Nature Photonics, Numer 12/3, 2018, Strona(/y) 165-172, ISSN 1749-4885
Wydawca: Nature Pub. Group
DOI: 10.1038/s41566-018-0109-4

Optical projection tomography for rapid whole mouse brain imaging

Autorzy: David Nguyen, Paul J. Marchand, Arielle L. Planchette, Julia Nilsson, Miguel Sison, Jérôme Extermann, Antonio Lopez, Marcin Sylwestrzak, Jessica Sordet-Dessimoz, Anja Schmidt-Christensen, Dan Holmberg, Dimitri Van De Ville, Theo Lasser
Opublikowane w: Biomedical Optics Express, Numer 8/12, 2017, Strona(/y) 5637, ISSN 2156-7085
Wydawca: The Optical Society
DOI: 10.1364/boe.8.005637

Correcting for photodestruction in super-resolution optical fluctuation imaging

Autorzy: Yves Peeters, Wim Vandenberg, Sam Duwé, Arno Bouwens, Tomáš Lukeš, Cyril Ruckebusch, Theo Lasser, Peter Dedecker
Opublikowane w: Scientific Reports, Numer 7/1, 2017, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-017-09666-4

Quantifying protein densities on cell membranes using super-resolution optical fluctuation imaging

Autorzy: Tomáš Lukeš, Daniela Glatzová, Zuzana Kvíčalová, Florian Levet, Aleš Benda, Sebastian Letschert, Markus Sauer, Tomáš Brdička, Theo Lasser, Marek Cebecauer
Opublikowane w: Nature Communications, Numer 8/1, 2017, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-017-01857-x

Autonomous Ultrafast Self-Healing Hydrogels by pH-Responsive Functional Nanofiber Gelators as Cell Matrices

Autorzy: Gačanin, J.; Hedrich, J.; Sieste, S.; Glasser, G.; Lieberwirth, I.; Schilling, C.; Fischer, S.; Barth, H.; Knoell, B.; Synatschke, C.; Weil, T.
Opublikowane w: Advanced Materials, Numer 31, 2019, ISSN 0935-9648
Wydawca: United Nations Industrial Developement Organization
DOI: 10.1002/adma.201805044

Lectin-Functionalized Composite Hydrogels for “Capture-and-Killing” of Carbapenem-Resistant Pseudomonas aeruginosa

Autorzy: N. Bodenberger, D. Kubiczek, D. Halbgebauer, V. Rimola, S. Wiese, D. Mayer, A. A. Rodriguez Alfonso, L. Ständker, S. Stenger, F. Rosenau
Opublikowane w: Biomacromolecules, Numer 19 (7), 2018, Strona(/y) 2472/2482, ISSN 1525-7797
Wydawca: American Chemical Society
DOI: 10.1021/acs.biomac.8b00089

Go with the flow or solitary confinement: a look inside the single-cell toolbox for isolation of rare and uncultured microbes

Autorzy: G. R. B. Huys, J. Raes
Opublikowane w: Current Opinion in Microbiology, Numer Vol. 44, 2018, Strona(/y) 1/8, ISSN 1369-5274
Wydawca: Elsevier BV
DOI: 10.1016/j.mib.2018.05.002

Orthogonally Stimulated Assembly/Disassembly of Depsi‐peptides by Rational Chemical Design

Autorzy: M. Pieszka, A. M. Sobota, J. Gačanin, T. Weil, D. Y. W. Ng
Opublikowane w: ChemBioChem, 2019, ISSN 1439-7633
Wydawca: Wiley-VCH
DOI: 10.1002/cbic.201800781m

Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota

Autorzy: T. Harach, N. Marungruang, N. Duthilleul, V. Cheatham, K. D. Mc Coy, G. Frisoni, J. J. Neher, F. Fåk, M. Jucker, T. Lasser, T. Bolmont
Opublikowane w: Scientific Reports, Numer 7/1, 2017, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/srep41802

Integrated culturing, modeling and transcriptomics uncovers complex interactions and emergent behavior in a three-species synthetic gut community

Autorzy: K. D’hoe, S. Vet, K. Faust, F. Moens, G. Falony, D. Gonze, V. Llorens-Rico, L. Gelens, J. Danckaert, L. De Vuyst and J. Raes
Opublikowane w: eLife, 2018, ISSN 2050-084X
Wydawca: eLife Sciences Publications
DOI: 10.7554/elife.37090

Growth of engineered Pseudomonas putida KT2440 on glucose, xylose, and arabinose: Hemicellulose hydrolysates and their major sugars as sustainable carbon sources

Autorzy: Wang, Y.; Horlamus, F.; Henkel, M.; Kovacic, F.; Schlaefle, S.; Hausmann, R.; Wittgens, A.; Rosenau, F.
Opublikowane w: GCB Bioenergy, Numer 11, 2019, ISSN 1757-1693
Wydawca: Wiley-VCH Verlag
DOI: 10.1111/gcbb.12590

Statistical parametric mapping of stimuli evoked changes in total blood flow velocity in the mouse cortex obtained with extended-focus optical coherence microscopy

Autorzy: Shamaei, Vincent K.; Bouwens, Arno; Szlag, Daniel; Lasser, Theo; Nguyen, David; Extermann, Jérôme; Marchand, Paul J.; Bolmont, Tristan
Opublikowane w: Biomedical Optics Express, Numer 1, 2017, Strona(/y) 1-15, ISSN 2156-7085
Wydawca: The Optical Society
DOI: 10.1364/BOE.8.000001

Single Molecule Localization and Discrimination of DNA–Protein Complexes by Controlled Translocation Through Nanocapillaries

Autorzy: Bulushev, Roman D.; Davis, Sebastian J.; Sebastian J Maerkl; Marion, Sanjin; Petrova, Ekaterina; Radenovic, Aleksandra
Opublikowane w: Nano Letters, Numer 1, 2016, Strona(/y) 7882–7890, ISSN 1530-6984
Wydawca: American Chemical Society
DOI: 10.1021/acs.nanolett.6b04165

Identifying microbial species by single-molecule DNA optical mapping and resampling statistics

Autorzy: Arno Bouwens, Jochem Deen, Raffaele Vitale, Laurens D’Huys, Vince Goyvaerts, Adrien Descloux, Doortje Borrenberghs, Kristin Grussmayer, Tomas Lukes, Rafael Camacho, Jia Su, Cyril Ruckebusch, Theo Lasser, Dimitri Van De Ville, Johan Hofkens, Aleksandra Radenovic, Kris Pieter Frans Janssen
Opublikowane w: NAR Genomics and Bioinformatics, Numer 2/1, 2020, ISSN 2631-9268
Wydawca: Oxford University Press
DOI: 10.1093/nargab/lqz007

Parameter-free image resolution estimation based on decorrelation analysis

Autorzy: A. Descloux, K. S. Grußmayer, A. Radenovic
Opublikowane w: Nature Methods, Numer 16/9, 2019, Strona(/y) 918-924, ISSN 1548-7091
Wydawca: Nature Publishing Group
DOI: 10.1038/s41592-019-0515-7

Supervised learning to quantify amyloidosis in whole brains of an Alzheimer’s disease mouse model acquired with optical projection tomography

Autorzy: David Nguyen, Virginie Uhlmann, Arielle L. Planchette, Paul J. Marchand, Dimitri Van De Ville, Theo Lasser, Aleksandra Radenovic
Opublikowane w: Biomedical Optics Express, Numer 10/6, 2019, Strona(/y) 3041, ISSN 2156-7085
Wydawca: The Optical Society
DOI: 10.1364/boe.10.003041

Biomedical Applications of DNA‐Based Hydrogels

Autorzy: Jasmina Gačanin, Christopher V. Synatschke, Tanja Weil
Opublikowane w: Advanced Functional Materials, Numer 30/4, 2019, Strona(/y) 1906253, ISSN 1616-301X
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.201906253

Comparison of Three Xylose Pathways in Pseudomonas putida KT2440 for the Synthesis of Valuable Products

Autorzy: Isabel Bator, Andreas Wittgens, Frank Rosenau, Till Tiso, Lars M. Blank
Opublikowane w: Frontiers in Bioengineering and Biotechnology, Numer 7, 2020, ISSN 2296-4185
Wydawca: Frontiers in Bioengineering and Biotechnology
DOI: 10.3389/fbioe.2019.00480

Fluorescent SAM analogues for methyltransferase based DNA labeling

Autorzy: Vince Goyvaerts, Sven Van Snick, Laurens D'Huys, Raffaele Vitale, Milena Helmer Lauer, Su Wang, Volker Leen, Wim Dehaen, Johan Hofkens
Opublikowane w: Chemical Communications, Numer 56/22, 2020, Strona(/y) 3317-3320, ISSN 1359-7345
Wydawca: Royal Society of Chemistry
DOI: 10.1039/c9cc08938a

A Cerberus‐Inspired Anti‐Infective Multicomponent Gatekeeper Hydrogel against Infections with the Emerging “Superbug” Yeast Candida auris

Autorzy: Dennis Kubiczek, Carolin Flaig, Heinz Raber, Steffen Dietz, Ann‐Kathrin Kissmann, Thomas Heerde, Nicholas Bodenberger, Andreas Wittgens, Melaine González‐Garcia, Fan Kang, Octavio L. Franco, Ludger Staendker, Anselmo J. Otero‐González, Paul Walther, Kay E. Gottschalk, Tanja Weil, Frank Rosenau
Opublikowane w: Macromolecular Bioscience, Numer 20/4, 2020, Strona(/y) 2000005, ISSN 1616-5187
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.202000005

High-speed multiplane structured illumination microscopy of living cells using an image-splitting prism

Autorzy: Adrien Descloux, Marcel Müller, Vytautas Navikas, Andreas Markwirth, Robin van den Eynde, Tomas Lukes, Wolfgang Hübner, Theo Lasser, Aleksandra Radenovic, Peter Dedecker, Thomas Huser
Opublikowane w: Nanophotonics, Numer 9/1, 2019, Strona(/y) 143-148, ISSN 2192-8614
Wydawca: De Gruyter
DOI: 10.1515/nanoph-2019-0346

Aptamers as promising agents in diagnostic and therapeutic applications.

Autorzy: D. Kubiczek, N. Bodenberger, F. Rosenau
Opublikowane w: Antimicrobial research: Novel bioknowledge and educational programs, 2017
Wydawca: A. Méndez-Vilas, Ed.

Jelly Bombs–Hydrogels as Weapons against Microorganisms.

Autorzy: N. Bodenberger, D. Kubiczek, D. Halbgebauer, C. Tanzer, N. Pfahler, F. Rosenau
Opublikowane w: Antimicrobial research: Novel bioknowledge and educational programs, 2017
Wydawca: A. Méndez-Vilas, Ed.

Alzheimer Disease - gut connection

Rezultaty

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