Breaking the Nonuniqueness Barrier in Electromagnetic Neuroimaging

Informazioni relative al progetto

BREAKBEN

ID dell’accordo di sovvenzione: 686865

DOI 10.3030/686865

Progetto chiuso

Data della firma CE 16 Novembre 2015

Data di avvio 1 Gennaio 2016

Data di completamento 31 Maggio 2019

Finanziato da

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Costo totale € 3 998 793,00

Contributo UE € 3 998 793,00

Coordinato da

AALTO KORKEAKOULUSAATIO SR
Finland

Risultati finali

Demonstrators, pilots, prototypes (2)

Demonstration of CDI in vivo

Demonstration of CDI in vivo.

MEG-MRI on healthy subjects

MEG-MRI on healthy subjects.

Documents, reports (4)

Guidelines for safety and regulatory requirements

Guidelines for safety and regulatory requirements.

Connectivity maps from human subject data

Connectivity maps from human subject data.

Dissemination activities

A report on dissemination activities during the project.

Analysis of the value of a priori information

Analysis of the value of a priori information.

Open Research Data Pilot (1)

Data Management Plan

Data Management Plan will be submitted in M6 and checked and updated for M36 and as appropriate during the project.

Websites, patent fillings, videos etc. (1)

External web-site

External web-site.

Pubblicazioni

Conference proceedings (27)

Ultra-sensitive SQUID instrumentation for MEG and NCI by ULF MRI

Autori: Rainer Körber
Pubblicato in: EMBEC & NBC 2017, IFMBE Proceedings, Numero 65, 2017, Pagina/e 795-798
Editore: Springer Singapore
DOI: 10.1007/978-981-10-5122-7_199

Towards direct neuronal current imaging via ultra-low-field MR

Autori: Nora Höfner and Rainer Körber and Marting Burghoff
Pubblicato in: Proceedings of the workshop Biosignal Processing 2016, 2016
Editore: Physikalisch-Technische Bundesanstalt

Calcified cortical tubers influence single dipole source localization

Autori: Alexander Hunold, Stephan Lau, Yoshio Okada, Christos Papadelis, Jens Haueisen
Pubblicato in: BIOMAG2016 Poster Session, Numero biennial, 2016
Editore: Biomag

Comparison of dipole localization to interictal spikesin individual and standardized BEM upon three different age group

Autori: Corinna Horn, Alexander Hunold, Jens Haueisen, Michael Funke
Pubblicato in: BIOMAG2016 Poster Session, Numero biennial, 2016
Editore: Biomag

A modular and field tolerant ultra-low-noise multichannel SQUID system for ULF MRI and high frequency MEG

Autori: Rainer Körber, Jan-Hendrik Storm, Dietmar Drung and Martin Burghoff
Pubblicato in: BIOMAG2016 Poster Session, Numero biennial, 2016
Editore: Biomag

Neuronal current imaging (NCI) by Ultra-Low-Field MRI

Autori: Nora Höfner, Rainer Körber, Jens Haueisen, Peter Hömmen and Martin Burghoff
Pubblicato in: BIOMAG2016 Poster Session, Numero biennial, 2016
Editore: Biomag

Optimized pipeline for the 3D co-registration of Low- and High-Field MRI

Autori: Guidotti R., Sinibaldi R., De Luca C., Conti A., Ilmoniemi R. J., Zevenhonen K. C. J., Magnelind P., Pizzella V., Romani G. L. and Della Penna S.
Pubblicato in: BIOMAG 2016 Poster session, Numero biannual, 2016
Editore: BIOMAG

Identifying pairwise interacting sources from the antisymmetric cross-bispectrum of EEG/MEG data

Autori: Federico Chella, Vittorio Pizzella, Filippo Zappasodi, Guido Nolte, Laura Marzetti
Pubblicato in: OHBM 2016 Poster session, Numero annual, 2016
Editore: OHBM

Accurate mapping of magnetic fields generated by an ultra-low-field MRI device

Autori: Aino E Tervo, Antti J Mäkinen, Risto J Ilmoniemi, and Koos C J Zevenhoven
Pubblicato in: BIOMAG2016 poster/abstract, Numero biennial, 2016, Pagina/e 407
Editore: Biomag

Breaking the Nonuniqueness Barrier in Electromagnetic Neuroimaging: the BREAKBEN project

Autori: Risto Ilmoniemi, Jens Haueisen, Mikko Kiviranta, Rainer Körber, Jyrki Mäkelä, Jukka Nenonen, Gian Luca Romani, and Koos Zevenhoven
Pubblicato in: BIOMAG2016 poster/abstract, Numero biennial, 2016, Pagina/e 409
Editore: Biomag

Recent advances in ultra-low-field MRI and its compatibility with other modalities

Autori: Koos C. J. Zevenhoven and Risto J. Ilmoniemi
Pubblicato in: BIOMAG2016 poster/abstract, Numero biennial, 2016, Pagina/e 410
Editore: Biomag

Eliminating co-registration in MEG–MRI: automatic nonlinear calibration of ULF MRI

Autori: Antti J. Mäkinen, Koos C. J. Zevenhoven, and Risto J. Ilmoniemi
Pubblicato in: Biomag2016 poster/abstract, Numero biennial, 2016, Pagina/e 406
Editore: Biomag

Current Density Imaging in the Head using Ultra-Low Field Magnetic Resonance - An Advanced Phantom Study

Autori: P. Hömmen, J-H. Storm, N. Höfner, A. Hunold, R. Machts, J. Haueisen and R. Körber
Pubblicato in: Biomag 2018 Poster Session, Numero biennial, 2018
Editore: Biomag

Computational and phantom-based evaluation of dc neuronal current imaging with ultra-low field magnetic resonance

Autori: J-H. Storm, A. M. Cassarà, N. Höfner, P. Hömmen, E. Neufeld, R. Körber and N. Kuster
Pubblicato in: Biomag 2018 Poster Session, Numero biennial, 2018
Editore: Biomag

Neuronal current imaging using 3D ultra-low field MRI - preliminary results

Autori: N. Höfner, J.-H. Storm, P. Hömmen, R. Körber
Pubblicato in: Biomag 2018 Poster Session, Numero biennial, 2018
Editore: Biomag

Simulated current density magnitudes and orientations for transcranial direct current stimulation montages used in depression studies

Autori: Alexander Hunold, Jens Haueisen
Pubblicato in: BaCI, Numero biennial, 2017
Editore: International Conference on Basic and Clinical Multimodal Imaging

Simulating the superposition of transcranial electric stimulations targeting the visual cortex

Autori: Alexander Hunold, Klaus Schellhorn, Jens Haueisen
Pubblicato in: BIOMAG2018, Numero biennial, 2018
Editore: Biomag

Flexible Stimulationshaube für TES Anwendungen: Technische Parameter und Stromdichtesimulationen

Autori: Alexander Hunold, Uwe Graichen, Klaus Schellhorn, Jens Haueisen
Pubblicato in: 62. Jahrestagung der DGKN 2018 mit Richard-Jung-Kolleg, Numero annual, 2018
Editore: Deutsche Gesellschaft für Klinische Neurophysiologie und funktionelle Bildgebung

Realization and Testing of a 3D Electrode Array for measuring Electric Potential Differences in a Volume Conductor

Autori: René Machts, Alexander Hunold, Jens Haueisen
Pubblicato in: 51. Jahrestagung der Biomedizinischen Technik und Dreiländertagung der Medizinischen Physik (BMTMedPhys), Numero annual, 2017
Editore: DGBMT im VDE

Simulation of the current density in the retina for transorbital electric current stimulation

Autori: Alexander Hunold, Anton Kresinsky, Berd A. Sabel, Jens Haueisen
Pubblicato in: "Workshop ""Innovative Verarbeitung bioelektrischer und biomagnetischer Signale""", Numero biennial, 2018
Editore: "Fachausschüsse ""Biosignale"" und ""Magnetische Methoden in der Medizin"" der DGBMT im VDE"

Concept of a physical head phantom MEG-MRI and NCI/CDI

Autori: Jens Haueisen, Alexander Hunold
Pubblicato in: "#brainTC", Numero annual, 2017
Editore: Department of Neuroscience and Biomedical Engineering @AaltoUniversity

AlexandSimulated current density and technical parameters of TES applied with a flexible cap

Autori: Alexander Hunold, Uwe Graichen, Klaus Schellhorn, Jens Haueisen
Pubblicato in: 52. Annual Conference of the German Society for Biomedical Engineering (DGBMT within VDE), Numero annual, 2018
Editore: DGBMT within VDE

Improving MEG–MRI co-registration for reliable MEG connectivity analysis

Autori: Federico Chella, Laura Marzetti, Matti Stenroos, Lauri Parkkonen, Risto Ilmoniemi, Gian Luca Romani, Vittorio Pizzella
Pubblicato in: BIOMAG2018 poster session, Numero biennial, 2018
Editore: Biomag

Understanding neural synchronization by combining good practice and novel methods in electrophysiological functional connectivity analysis

Autori: Laura Marzetti
Pubblicato in: 19th IOP World Congress, Numero biennial, 2018
Editore: International Organization of Psychophysiology

Effects of MEG–MRI coregistration error on functional connectivity estimates

Autori: Federico Chella, Laura Marzetti, Matti Stenroos, Lauri Parkkonen, Risto Ilmoniemi, Gian Luca Romani, Vittorio Pizzella
Pubblicato in: OHBM 2017 poster session, Numero annual, 2017
Editore: OHBM

Large-scale synchronization in ongoing brain activity by multidimensional connectivity

Autori: Laura Marzetti
Pubblicato in: BIOMAG2018, Numero biennial, 2018
Editore: Biomag

Ultra-sensitive SQUID system for pulsed field applications

Autori: Eva Al-Dabbagh, Peter Hömmen, Jan-Hendrik Storm, Nora Höfner, Rainer Körber
Pubblicato in: EUCAS 2017 Poster Session, Numero biennial, 2017
Editore: EUCAS

Peer reviewed articles (19)

Ultra-sensitive SQUID Systems for Pulsed Fields—Degaussing Superconducting Pick-Up Coils

Autori: Eva Al-Dabbagh, Jan-Hendrik Storm, Rainer Korber
Pubblicato in: IEEE Transactions on Applied Superconductivity, Numero 28/4, 2018, Pagina/e 1-5, ISSN 1051-8223
Editore: Institute of Electrical and Electronics Engineers
DOI: 10.1109/TASC.2018.2797544

SQUIDs in biomagnetism: a roadmap towards improved healthcare

Autori: Rainer Körber, Jan-Hendrik Storm, Hugh Seton, Jyrki P Mäkelä, Ritva Paetau, Lauri Parkkonen, Christoph Pfeiffer, Bushra Riaz, Justin F Schneiderman, Hui Dong, Seong-min Hwang, Lixing You, Ben Inglis, John Clarke, Michelle A Espy, Risto J Ilmoniemi, Per E Magnelind, Andrei N Matlashov, Jaakko O Nieminen, Petr L Volegov, Koos C J Zevenhoven, Nora Höfner, Martin Burghoff, Keiji Enpuku, S Y Yang,
Pubblicato in: Superconductor Science and Technology, Numero 29/11, 2016, Pagina/e 113001, ISSN 0953-2048
Editore: Institute of Physics Publishing
DOI: 10.1088/0953-2048/29/11/113001

A modular, extendible and field-tolerant multichannel vector magnetometer based on current sensor SQUIDs

Autori: J-H Storm, D Drung, M Burghoff, R Körber
Pubblicato in: Superconductor Science and Technology, Numero 29/9, 2016, Pagina/e 094001, ISSN 0953-2048
Editore: Institute of Physics Publishing
DOI: 10.1088/0953-2048/29/9/094001

Impact of the reference choice on scalp EEG connectivity estimation

Autori: Federico Chella, Vittorio Pizzella, Filippo Zappasodi, Laura Marzetti
Pubblicato in: Journal of Neural Engineering, Numero 13/3, 2016, Pagina/e 036016, ISSN 1741-2560
Editore: Institute of Physics Publishing
DOI: 10.1088/1741-2560/13/3/036016

Bispectral pairwise interacting source analysis for identifying systems of cross-frequency interacting brain sources from electroencephalographic or magnetoencephalographic signals

Autori: Federico Chella, Vittorio Pizzella, Filippo Zappasodi, Guido Nolte, Laura Marzetti
Pubblicato in: Physical Review E, Numero 93/5, 2016, ISSN 2470-0045
Editore: American Physical Society
DOI: 10.1103/PhysRevE.93.052420

An ultra-sensitive and wideband magnetometer based on a superconducting quantum interference devic

Autori: Jan-Hendrik Storm, Peter Hömmen, Diemtar Drung, Rainer Körber
Pubblicato in: Applied Physics Letters, Numero weekly, 2017, Pagina/e 072603-1 - 072603-4, ISSN 0003-6951
Editore: American Institute of Physics
DOI: 10.1063/1.4976823

Demonstration of full tensor current density imaging using ultra-low field MRI

Autori: P. Hömmen, J.-H. Storm, N. Höfner, R. Körber
Pubblicato in: Magnetic Resonance Imaging, 2019, ISSN 0730-725X
Editore: Elsevier BV
DOI: 10.1016/j.mri.2019.03.010

Theta-burst stimulation causally affects side perception in the Deutsch’s octave illusion

Autori: Paolo Capotosto, Stefania della Penna, Vittorio Pizzella, Filippo Zappasodi, Gian Luca Romani, Risto J. Ilmoniemi, Alfredo Brancucci
Pubblicato in: Scientific Reports, Numero 8/1, 2018, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-018-31248-1

The impact of improved MEG–MRI co-registration on MEG connectivity analysis

Autori: Federico Chella, Laura Marzetti, Matti Stenroos, Lauri Parkkonen, Risto J. Ilmoniemi, Gian Luca Romani, Vittorio Pizzella
Pubblicato in: NeuroImage, Numero 197, 2019, Pagina/e 354-367, ISSN 1053-8119
Editore: Academic Press
DOI: 10.1016/j.neuroimage.2019.04.061

Alpha and alpha-beta phase synchronization mediate the recruitment of the visuospatial attention network through the Superior Longitudinal Fasciculus

Autori: Antea D'Andrea, Federico Chella, Tom R. Marshall, Vittorio Pizzella, Gian Luca Romani, Ole Jensen, Laura Marzetti
Pubblicato in: NeuroImage, Numero 188, 2019, Pagina/e 722-732, ISSN 1053-8119
Editore: Academic Press
DOI: 10.1016/j.neuroimage.2018.12.056

A comparative study of the robustness of frequency--domain connectivity measures to finite data length

Autori: Sommariva, Sara; Sorrentino, Alberto; Piana, Michele; Pizzella, Vittorio; Marzetti, Laura
Pubblicato in: Brain Topography, Numero 1, 2017, ISSN 0896-0267
Editore: Kluwer Academic/Plenum Publishers

Disclosing large-scale directed functional connections in MEG with the multivariate phase slope index

Autori: Alessio Basti, Vittorio Pizzella, Federico Chella, Gian Luca Romani, Guido Nolte, Laura Marzetti
Pubblicato in: NeuroImage, Numero 175, 2018, Pagina/e 161-175, ISSN 1053-8119
Editore: Academic Press
DOI: 10.1016/j.neuroimage.2018.03.004

Non-linear Analysis of Scalp EEG by Using Bispectra: The Effect of the Reference Choice

Autori: Federico Chella, Antea D'Andrea, Alessio Basti, Vittorio Pizzella, Laura Marzetti
Pubblicato in: Frontiers in Neuroscience, Numero 11, 2017, ISSN 1662-453X
Editore: Frontiers
DOI: 10.3389/fnins.2017.00262

Optimized 3D co-registration of ultra-low-field and high-field magnetic resonance images

Autori: Roberto Guidotti, Raffaele Sinibaldi, Cinzia De Luca, Allegra Conti, Risto J. Ilmoniemi, Koos C. J. Zevenhoven, Per E. Magnelind, Vittorio Pizzella, Cosimo Del Gratta, Gian Luca Romani, Stefania Della Penna
Pubblicato in: PLOS ONE, Numero 13/3, 2018, Pagina/e e0193890, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0193890

Unshielded SQUID Sensors for Ultra-Low-Field Magnetic Resonance Imaging

Autori: Juho Luomahaara, Mikko Kiviranta, Leif Gronberg, Koos C. J. Zevenhoven, Petteri Laine
Pubblicato in: IEEE Transactions on Applied Superconductivity, Numero 28/4, 2018, Pagina/e 1-4, ISSN 1051-8223
Editore: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tasc.2018.2791022

Automatic Spatial Calibration of Ultra-Low-Field MRI for High-Accuracy Hybrid MEG–MRI

Autori: Antti J. Makinen, Koos C. J. Zevenhoven, Risto J. Ilmoniemi
Pubblicato in: IEEE Transactions on Medical Imaging, Numero 38/6, 2019, Pagina/e 1317-1327, ISSN 0278-0062
Editore: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tmi.2019.2905934

Side-wall spacer passivated sub- μ m Josephson junction fabrication process

Autori: Leif Grönberg, Mikko Kiviranta, Visa Vesterinen, Janne Lehtinen, Slawomir Simbierowicz, Juho Luomahaara, Mika Prunnila, Juha Hassel
Pubblicato in: Superconductor Science and Technology, Numero 30/12, 2017, Pagina/e 125016, ISSN 0953-2048
Editore: Institute of Physics Publishing
DOI: 10.1088/1361-6668/aa9411

Head phantoms for electroencephalography and transcranial electric stimulation: a skull material study

Autori: Alexander Hunold, Daniel Strohmeier, Patrique Fiedler, Jens Haueisen
Pubblicato in: Biomedical Engineering / Biomedizinische Technik, Numero 63/6, 2018, Pagina/e 683-689, ISSN 0013-5585
Editore: Fachverlag Schiele and Schoen GmbH
DOI: 10.1515/bmt-2017-0069

Real-Time Clustered Multiple Signal Classification (RTC-MUSIC)

Autori: Christoph Dinh, Lorenz Esch, Johannes Rühle, Steffen Bollmann, Daniel Güllmar, Daniel Baumgarten, Matti S. Hämäläinen, Jens Haueisen
Pubblicato in: Brain Topography, Numero 31/1, 2018, Pagina/e 125-128, ISSN 0896-0267
Editore: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s10548-017-0586-7

Thesis and dissertations (6)

Suprajohtavan kvantti-interferenssilaitteen automatisoitu virittäminen aivokuvantamista varten [Automated tuning of a superconducting quantum interference device for brain imaging]

Autori: Mikko Luukinen
Pubblicato in: 2017
Editore: NA

Superconducting prepolarization coil for ultra-low-field MRI

Autori: Iiro Lehto
Pubblicato in: 2017
Editore: NA

Noise optimization of multi-layer insulation in liquid-helium cryostat for brain imaging

Autori: Aino Tervo
Pubblicato in: 2016
Editore: NA

Assessing the value of a priori information in solving the MEG inverse problem

Autori: Gavriela Vranou
Pubblicato in: 2019
Editore: NA

Konstruktion eines Gestells mit stufenlosem Manipulator der z-Achse für unterschiedliche Kryostaten innerhalb eines bestehenden Messsystems zur Probanden- und Probenmessung in magnetisch geschirmten Räumen

Autori: Sebastian Neuber
Pubblicato in: 2018
Editore: NA

Hoch-sensitives SQUID-Messsystem für Anwendungen mit gepultsten Feldern

Autori: Eva Al-Dabbagh
Pubblicato in: 2017
Editore: NA