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Innovative Dermatology Healthcare based on Label-Free Spectral Optoacoustic Mesoscopy

Objective

Multispectral Optoacoustic Tomography (MSOT) brings a revolution to bio-optical imaging. Being insensitive to photon scattering, MSOT dramatically improves upon conventional bio-optic barriers by enabling (1) three-dimensional high-resolution optical imaging deep inside tissues (several millimetres to centimetres), by (2) high-scalability, ranging from optical-resolution microscopy to acoustic-resolution optical mesoscopy and macroscopy and by (3) novel label-free anatomical, physiological and molecular contrast at the tissue and single-cell-level, based on spectrally-resolved optical absorption. MSOT, originally supported by an ERC Advanced Award (2008) (TUM: Prof. Ntziachristos), is already commercialized by iThera Medical for macroscopy with systems sold around the world for small animal imaging. In parallel, ERC MSOT funding developed a mesoscopic implementation, termed raster-scan optoacoustic mesoscopy (RSOM), which has demonstrated innovative imaging capacity at 1-5mm depths.
Driven by leading dermatologists (TUM: Prof. Biedermann; SUR: Prof. Costanzo) and market leader SMEs in optoacoustic and ultrasound technology (iThera, Rayfos, Sonaxis), INNODERM will design and prototype a handheld, portable, scalable, label-free RSOM device for point-of care dermatology applications, based on recommendations developed under an ERC proof of concept grant (2013) on MSOT. INNODERM brings together key photonic & ultrasound technologies and will validate the technical and economic viability of RSOM in dermatology suites for fast diagnosis and skin disease monitoring. RSOM can go beyond the abilities of current optical or optoacoustic devices and offer a paradigm shift in dermatology imaging, substantiating successful business cases.

Field of science

  • /natural sciences/physical sciences/acoustics/ultrasound
  • /medical and health sciences/clinical medicine/dermatology

Call for proposal

H2020-ICT-2015
See other projects for this call

Funding Scheme

IA - Innovation action

Coordinator

TECHNISCHE UNIVERSITAET MUENCHEN
Address
Arcisstrasse 21
80333 Muenchen
Germany
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 432 350

Participants (5)

SONAXIS
France
EU contribution
€ 471 238,25
Address
Rue Emilie Du Chatelet 1
25000 Besancon
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
RAYFOS LTD
United Kingdom
EU contribution
€ 496 133,75
Address
Winton House Winton Square
RG21 8EN Basingstoke
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ITHERA MEDICAL GMBH
Germany
EU contribution
€ 724 868,38
Address
Zielstattstrasse 13
81379 Munchen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA

Participation ended

Italy
EU contribution
€ 0
Address
Piazzale Aldo Moro 5
00185 Roma
Activity type
Higher or Secondary Education Establishments
HUMANITAS UNIVERSITY
Italy
EU contribution
€ 745 288,75
Address
Via Rita Levi Montalcini Snc
20090 Pieve Emanuele
Activity type
Higher or Secondary Education Establishments