Gene2Skin - Roadmap for advanced genetic engineering-based skin therapies

Project Information

Gene2Skin

Grant agreement ID: 692221

DOI

10.3030/692221

Project closed

EC signature date 6 November 2015

Start date 1 December 2015

End date 30 November 2018

Funded under

• SPREADING EXCELLENCE AND WIDENING PARTICIPATION

Total cost

€ 992 068,75

EU contribution

€ 992 068,75

Coordinated by

UNIVERSIDADE DO MINHO
Portugal

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (9)

Report on the dissemination of the project activities to the general public

A report on the dissemination of the project activities and outcomes to the general public will be made.

Report on gender representation on the activities of the project

A report on gender representation on the activities of the project will be performed

Statement of completion of task 4.6

Statement of completion of task 3.6

Report on the dissemination of the project activities to industrial players and investors

A report on the dissemination of the project activities to industrial players and investors and respective feedback will be performed.

Report on the organized workshops

A report will be made on the workshops organized by RCSI and KCL

Report on the dissemination of the project outcomes to patients and clinicians

Report on the dissemination of the project outcomes to patients and clinicians.

Reports on dissemination of the project in the scientific community

Report on the dissemination of the project outcomes to the scientific community will be peformed.

Report on the Project retreat, international conferences and summer schools

A report on several activities organized in the scope of the project will be made, namely on the project retreat, on the jointly organized international conferences and on the summer schools organized by UMINHO.

Report on the outreach of project activities to the regulatory authorities

A report on the outreach of project activities to the regulatory authorities and organizations will be performed.

Websites, patent fillings, videos etc. (1)

Website and newsletter creation

A website and a periodic newsletter will be created and periodically released.

Publications

Peer reviewed articles (19)

Poly(hydroxybutyrate- co -hydroxyvalerate) Bilayer Skin Tissue Engineering Constructs with Improved Epidermal Rearrangement

Author(s): Alessandra Zonari, Mariana T. Cerqueira, Silviene Novikoff, Alfredo M. Goes, Alexandra P. Marques, Vitor M. Correlo, Rui L. Reis
Published in: Macromolecular Bioscience, Issue 14/7, 2014, Page(s) 977-990, ISSN 1616-5187
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.201400005

Gellan Gum-Hyaluronic Acid Spongy-like Hydrogels and Cells from Adipose Tissue Synergize Promoting Neoskin Vascularization

Author(s): Mariana Teixeira Cerqueira, Lucília Pereira da Silva, Tírcia Carlos Santos, Rogério Pedro Pirraco, Vítor Manuel Correlo, Rui Luís Reis, Alexandra Pinto Marques
Published in: ACS Applied Materials & Interfaces, Issue 6/22, 2014, Page(s) 19668-19679, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/am504520j

Human Skin Cell Fractions Fail to Self-Organize Within a Gellan Gum/Hyaluronic Acid Matrix but Positively Influence Early Wound Healing

Author(s): Mariana T. Cerqueira, Lucília P. da Silva, Tírcia C. Santos, Rogério P. Pirraco, Vitor M. Correlo, Alexandra P. Marques, Rui L. Reis
Published in: Tissue Engineering Part A, Issue 20/9-10, 2014, Page(s) 1369-1378, ISSN 1937-3341
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tea.2013.0460

Human Adipose Stem Cells Cell Sheet Constructs Impact Epidermal Morphogenesis in Full-Thickness Excisional Wounds

Author(s): M. T. Cerqueira, R. P. Pirraco, T. C. Santos, D. B. Rodrigues, A. M. Frias, A. R. Martins, R. L. Reis, A. P. Marques
Published in: Biomacromolecules, Issue 14/11, 2013, Page(s) 3997-4008, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/bm4011062

A two-component pre-seeded dermal–epidermal scaffold

Author(s): I.P. Monteiro, D. Gabriel, B.P. Timko, M. Hashimoto, S. Karajanagi, R. Tong, A.P. Marques, R.L. Reis, D.S. Kohane
Published in: Acta Biomaterialia, Issue 10/12, 2014, Page(s) 4928-4938, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2014.08.029

Cell sheet technology-driven re-epithelialization and neovascularization of skin wounds

Author(s): M.T. Cerqueira, R.P. Pirraco, A.R. Martins, T.C. Santos, R.L. Reis, A.P. Marques
Published in: Acta Biomaterialia, Issue 10/7, 2014, Page(s) 3145-3155, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2014.03.006

Boosting and Rescuing Epidermal Superior Population from Fresh Keratinocyte Cultures

Author(s): Mariana T. Cerqueira, Ana M. Frias, Rui L. Reis, Alexandra P. Marques
Published in: Stem Cells and Development, Issue 23/1, 2014, Page(s) 34-43, ISSN 1547-3287
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/scd.2013.0038

Stem Cell-Containing Hyaluronic Acid-Based Spongy Hydrogels for Integrated Diabetic Wound Healing

Author(s): Lucília Pereira da Silva, Tírcia Carlos Santos, Daniel Barreira Rodrigues, Rogério Pedro Pirraco, Mariana Teixeira Cerqueira, Rui Luís Reis, Vitor Manuel Correlo, Alexandra Pinto Marques
Published in: Journal of Investigative Dermatology, Issue 137/7, 2017, Page(s) 1541-1551, ISSN 0022-202X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2017.02.976

Spray-assisted layer-by-layer assembly on hyaluronic acid scaffolds for skin tissue engineering

Author(s): Isa P. Monteiro, Anita Shukla, Alexandra P. Marques, Rui L. Reis, Paula T. Hammond
Published in: Journal of Biomedical Materials Research Part A, Issue 15493296, 2015, Page(s) 330-340, ISSN 1549-3296
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/jbm.a.35178

Boosting and Rescuing Epidermal Superior Population from Fresh Keratinocyte Cultures

Author(s): Mariana T. Cerqueira, Ana M. Frias, Rui L. Reis, Alexandra P. Marques
Published in: Stem Cells and Development, Issue 15473287, 2014, Page(s) 34-43, ISSN 1547-3287
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/scd.2013.0038

Epidermis recreation in spongy-like hydrogels

Author(s): M.T. Cerqueira, L.P. da Silva, V.M. Correlo, R.L. Reis, A.P. Marques
Published in: Materials Today, Issue 13697021, 2015, Page(s) 468-469, ISSN 1369-7021
Publisher: Elsevier BV
DOI: 10.1016/j.mattod.2015.08.018

Cell sheet technology-driven re-epithelialization and neovascularization of skin wounds

Author(s): M.T. Cerqueira, R.P. Pirraco, A.R. Martins, T.C. Santos, R.L. Reis, A.P. Marques
Published in: Acta Biomaterialia, Issue 17427061, 2014, Page(s) 3145-3155, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2014.03.006

A two-component pre-seeded dermal–epidermal scaffold

Author(s): I.P. Monteiro, D. Gabriel, B.P. Timko, M. Hashimoto, S. Karajanagi, R. Tong, A.P. Marques, R.L. Reis, D.S. Kohane
Published in: Acta Biomaterialia, Issue 17427061, 2014, Page(s) 4928-4938, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2014.08.029

Gellan Gum-Hyaluronic Acid Spongy-like Hydrogels and Cells from Adipose Tissue Synergize Promoting Neoskin Vascularization

Author(s): Mariana Teixeira Cerqueira, Lucília Pereira da Silva, Tírcia Carlos Santos, Rogério Pedro Pirraco, Vítor Manuel Correlo, Rui Luís Reis, Alexandra Pinto Marques
Published in: ACS Applied Materials & Interfaces, Issue 19448244, 2014, Page(s) 19668-19679, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/am504520j

Human Skin Cell Fractions Fail to Self-Organize Within a Gellan Gum/Hyaluronic Acid Matrix but Positively Influence Early Wound Healing

Author(s): Mariana T. Cerqueira, Lucília P. da Silva, Tírcia C. Santos, Rogério P. Pirraco, Vitor M. Correlo, Alexandra P. Marques, Rui L. Reis
Published in: Tissue Engineering Part A, Issue 19373341, 2014, Page(s) 1369-1378, ISSN 1937-3341
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tea.2013.0460

Poly(hydroxybutyrate- co -hydroxyvalerate) Bilayer Skin Tissue Engineering Constructs with Improved Epidermal Rearrangement

Author(s): Alessandra Zonari, Mariana T. Cerqueira, Silviene Novikoff, Alfredo M. Goes, Alexandra P. Marques, Vitor M. Correlo, Rui L. Reis
Published in: Macromolecular Bioscience, Issue 16165187, 2014, Page(s) 977-990, ISSN 1616-5187
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.201400005

Human Adipose Stem Cells Cell Sheet Constructs Impact Epidermal Morphogenesis in Full-Thickness Excisional Wounds

Author(s): M. T. Cerqueira, R. P. Pirraco, T. C. Santos, D. B. Rodrigues, A. M. Frias, A. R. Martins, R. L. Reis, A. P. Marques
Published in: Biomacromolecules, Issue 15257797, 2013, Page(s) 3997-4008, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/bm4011062

Epidermis recreation in spongy-like hydrogels

Author(s): M.T. Cerqueira, L.P. da Silva, V.M. Correlo, R.L. Reis, A.P. Marques
Published in: Materials Today, Issue 18/8, 2015, Page(s) 468-469, ISSN 1369-7021
Publisher: Elsevier BV
DOI: 10.1016/j.mattod.2015.08.018

Spray-assisted layer-by-layer assembly on hyaluronic acid scaffolds for skin tissue engineering

Author(s): Isa P. Monteiro, Anita Shukla, Alexandra P. Marques, Rui L. Reis, Paula T. Hammond
Published in: Journal of Biomedical Materials Research Part A, Issue 103/1, 2015, Page(s) 330-340, ISSN 1549-3296
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/jbm.a.35178

Book chapters (2)

Interfollicular Epidermal Stem Cells: Boosting and Rescuing from Adult Skin

Author(s): Mariana T. Cerqueira, Ana M. Frias, Rui L. Reis, Alexandra P. Marques
Published in: Skin Stem Cells, 2013, Page(s) 1-9, ISBN 978-1-62703-330-5
Publisher: Humana Press
DOI: 10.1007/978-1-62703-330-5_1

Interfollicular Epidermal Stem Cells: Boosting and Rescuing from Adult Skin

Author(s): Mariana T. Cerqueira, Ana M. Frias, Rui L. Reis, Alexandra P. Marques
Published in: Skin Stem Cells, 2013, Page(s) 1-9, ISBN 978-1-62703-330-5
Publisher: Humana Press
DOI: 10.1007/978-1-62703-330-5_1

Intellectual Property Rights

Patent (1)

FIBERS WITH SEGMENTS, THEIR PREPARATION AND APPLICATIONS THEREOF

Application/Publication number: PCT IB2017/056654
Date: 2017-10-26
Applicant(s): UNIVERSIDADE DO MINHO