Gene2Skin - Roadmap for advanced genetic engineering-based skin therapies

Informations projet

Gene2Skin

N° de convention de subvention: 692221

DOI

10.3030/692221

Projet clôturé

Date de signature de la CE 6 Novembre 2015

Date de début 1 Decembre 2015

Date de fin 30 Novembre 2018

Financé au titre de

• SPREADING EXCELLENCE AND WIDENING PARTICIPATION

Coût total

€ 992 068,75

Contribution de l’UE

€ 992 068,75

Coordonné par

UNIVERSIDADE DO MINHO
Portugal

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Documents, reports (9)

Report on the dissemination of the project activities to the general public

A report on the dissemination of the project activities and outcomes to the general public will be made.

Report on gender representation on the activities of the project

A report on gender representation on the activities of the project will be performed

Statement of completion of task 4.6

Statement of completion of task 3.6

Report on the dissemination of the project activities to industrial players and investors

A report on the dissemination of the project activities to industrial players and investors and respective feedback will be performed.

Report on the organized workshops

A report will be made on the workshops organized by RCSI and KCL

Report on the dissemination of the project outcomes to patients and clinicians

Report on the dissemination of the project outcomes to patients and clinicians.

Reports on dissemination of the project in the scientific community

Report on the dissemination of the project outcomes to the scientific community will be peformed.

Report on the Project retreat, international conferences and summer schools

A report on several activities organized in the scope of the project will be made, namely on the project retreat, on the jointly organized international conferences and on the summer schools organized by UMINHO.

Report on the outreach of project activities to the regulatory authorities

A report on the outreach of project activities to the regulatory authorities and organizations will be performed.

Websites, patent fillings, videos etc. (1)

Website and newsletter creation

A website and a periodic newsletter will be created and periodically released.

Publications

Peer reviewed articles (19)

Poly(hydroxybutyrate- co -hydroxyvalerate) Bilayer Skin Tissue Engineering Constructs with Improved Epidermal Rearrangement

Auteurs: Alessandra Zonari, Mariana T. Cerqueira, Silviene Novikoff, Alfredo M. Goes, Alexandra P. Marques, Vitor M. Correlo, Rui L. Reis
Publié dans: Macromolecular Bioscience, Numéro 14/7, 2014, Page(s) 977-990, ISSN 1616-5187
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.201400005

Gellan Gum-Hyaluronic Acid Spongy-like Hydrogels and Cells from Adipose Tissue Synergize Promoting Neoskin Vascularization

Auteurs: Mariana Teixeira Cerqueira, Lucília Pereira da Silva, Tírcia Carlos Santos, Rogério Pedro Pirraco, Vítor Manuel Correlo, Rui Luís Reis, Alexandra Pinto Marques
Publié dans: ACS Applied Materials & Interfaces, Numéro 6/22, 2014, Page(s) 19668-19679, ISSN 1944-8244
Éditeur: American Chemical Society
DOI: 10.1021/am504520j

Human Skin Cell Fractions Fail to Self-Organize Within a Gellan Gum/Hyaluronic Acid Matrix but Positively Influence Early Wound Healing

Auteurs: Mariana T. Cerqueira, Lucília P. da Silva, Tírcia C. Santos, Rogério P. Pirraco, Vitor M. Correlo, Alexandra P. Marques, Rui L. Reis
Publié dans: Tissue Engineering Part A, Numéro 20/9-10, 2014, Page(s) 1369-1378, ISSN 1937-3341
Éditeur: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tea.2013.0460

Human Adipose Stem Cells Cell Sheet Constructs Impact Epidermal Morphogenesis in Full-Thickness Excisional Wounds

Auteurs: M. T. Cerqueira, R. P. Pirraco, T. C. Santos, D. B. Rodrigues, A. M. Frias, A. R. Martins, R. L. Reis, A. P. Marques
Publié dans: Biomacromolecules, Numéro 14/11, 2013, Page(s) 3997-4008, ISSN 1525-7797
Éditeur: American Chemical Society
DOI: 10.1021/bm4011062

A two-component pre-seeded dermal–epidermal scaffold

Auteurs: I.P. Monteiro, D. Gabriel, B.P. Timko, M. Hashimoto, S. Karajanagi, R. Tong, A.P. Marques, R.L. Reis, D.S. Kohane
Publié dans: Acta Biomaterialia, Numéro 10/12, 2014, Page(s) 4928-4938, ISSN 1742-7061
Éditeur: Elsevier BV
DOI: 10.1016/j.actbio.2014.08.029

Cell sheet technology-driven re-epithelialization and neovascularization of skin wounds

Auteurs: M.T. Cerqueira, R.P. Pirraco, A.R. Martins, T.C. Santos, R.L. Reis, A.P. Marques
Publié dans: Acta Biomaterialia, Numéro 10/7, 2014, Page(s) 3145-3155, ISSN 1742-7061
Éditeur: Elsevier BV
DOI: 10.1016/j.actbio.2014.03.006

Boosting and Rescuing Epidermal Superior Population from Fresh Keratinocyte Cultures

Auteurs: Mariana T. Cerqueira, Ana M. Frias, Rui L. Reis, Alexandra P. Marques
Publié dans: Stem Cells and Development, Numéro 23/1, 2014, Page(s) 34-43, ISSN 1547-3287
Éditeur: Mary Ann Liebert Inc.
DOI: 10.1089/scd.2013.0038

Stem Cell-Containing Hyaluronic Acid-Based Spongy Hydrogels for Integrated Diabetic Wound Healing

Auteurs: Lucília Pereira da Silva, Tírcia Carlos Santos, Daniel Barreira Rodrigues, Rogério Pedro Pirraco, Mariana Teixeira Cerqueira, Rui Luís Reis, Vitor Manuel Correlo, Alexandra Pinto Marques
Publié dans: Journal of Investigative Dermatology, Numéro 137/7, 2017, Page(s) 1541-1551, ISSN 0022-202X
Éditeur: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2017.02.976

Spray-assisted layer-by-layer assembly on hyaluronic acid scaffolds for skin tissue engineering

Auteurs: Isa P. Monteiro, Anita Shukla, Alexandra P. Marques, Rui L. Reis, Paula T. Hammond
Publié dans: Journal of Biomedical Materials Research Part A, Numéro 15493296, 2015, Page(s) 330-340, ISSN 1549-3296
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/jbm.a.35178

Boosting and Rescuing Epidermal Superior Population from Fresh Keratinocyte Cultures

Auteurs: Mariana T. Cerqueira, Ana M. Frias, Rui L. Reis, Alexandra P. Marques
Publié dans: Stem Cells and Development, Numéro 15473287, 2014, Page(s) 34-43, ISSN 1547-3287
Éditeur: Mary Ann Liebert Inc.
DOI: 10.1089/scd.2013.0038

Epidermis recreation in spongy-like hydrogels

Auteurs: M.T. Cerqueira, L.P. da Silva, V.M. Correlo, R.L. Reis, A.P. Marques
Publié dans: Materials Today, Numéro 13697021, 2015, Page(s) 468-469, ISSN 1369-7021
Éditeur: Elsevier BV
DOI: 10.1016/j.mattod.2015.08.018

Cell sheet technology-driven re-epithelialization and neovascularization of skin wounds

Auteurs: M.T. Cerqueira, R.P. Pirraco, A.R. Martins, T.C. Santos, R.L. Reis, A.P. Marques
Publié dans: Acta Biomaterialia, Numéro 17427061, 2014, Page(s) 3145-3155, ISSN 1742-7061
Éditeur: Elsevier BV
DOI: 10.1016/j.actbio.2014.03.006

A two-component pre-seeded dermal–epidermal scaffold

Auteurs: I.P. Monteiro, D. Gabriel, B.P. Timko, M. Hashimoto, S. Karajanagi, R. Tong, A.P. Marques, R.L. Reis, D.S. Kohane
Publié dans: Acta Biomaterialia, Numéro 17427061, 2014, Page(s) 4928-4938, ISSN 1742-7061
Éditeur: Elsevier BV
DOI: 10.1016/j.actbio.2014.08.029

Gellan Gum-Hyaluronic Acid Spongy-like Hydrogels and Cells from Adipose Tissue Synergize Promoting Neoskin Vascularization

Auteurs: Mariana Teixeira Cerqueira, Lucília Pereira da Silva, Tírcia Carlos Santos, Rogério Pedro Pirraco, Vítor Manuel Correlo, Rui Luís Reis, Alexandra Pinto Marques
Publié dans: ACS Applied Materials & Interfaces, Numéro 19448244, 2014, Page(s) 19668-19679, ISSN 1944-8244
Éditeur: American Chemical Society
DOI: 10.1021/am504520j

Human Skin Cell Fractions Fail to Self-Organize Within a Gellan Gum/Hyaluronic Acid Matrix but Positively Influence Early Wound Healing

Auteurs: Mariana T. Cerqueira, Lucília P. da Silva, Tírcia C. Santos, Rogério P. Pirraco, Vitor M. Correlo, Alexandra P. Marques, Rui L. Reis
Publié dans: Tissue Engineering Part A, Numéro 19373341, 2014, Page(s) 1369-1378, ISSN 1937-3341
Éditeur: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tea.2013.0460

Poly(hydroxybutyrate- co -hydroxyvalerate) Bilayer Skin Tissue Engineering Constructs with Improved Epidermal Rearrangement

Auteurs: Alessandra Zonari, Mariana T. Cerqueira, Silviene Novikoff, Alfredo M. Goes, Alexandra P. Marques, Vitor M. Correlo, Rui L. Reis
Publié dans: Macromolecular Bioscience, Numéro 16165187, 2014, Page(s) 977-990, ISSN 1616-5187
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.201400005

Human Adipose Stem Cells Cell Sheet Constructs Impact Epidermal Morphogenesis in Full-Thickness Excisional Wounds

Auteurs: M. T. Cerqueira, R. P. Pirraco, T. C. Santos, D. B. Rodrigues, A. M. Frias, A. R. Martins, R. L. Reis, A. P. Marques
Publié dans: Biomacromolecules, Numéro 15257797, 2013, Page(s) 3997-4008, ISSN 1525-7797
Éditeur: American Chemical Society
DOI: 10.1021/bm4011062

Epidermis recreation in spongy-like hydrogels

Auteurs: M.T. Cerqueira, L.P. da Silva, V.M. Correlo, R.L. Reis, A.P. Marques
Publié dans: Materials Today, Numéro 18/8, 2015, Page(s) 468-469, ISSN 1369-7021
Éditeur: Elsevier BV
DOI: 10.1016/j.mattod.2015.08.018

Spray-assisted layer-by-layer assembly on hyaluronic acid scaffolds for skin tissue engineering

Auteurs: Isa P. Monteiro, Anita Shukla, Alexandra P. Marques, Rui L. Reis, Paula T. Hammond
Publié dans: Journal of Biomedical Materials Research Part A, Numéro 103/1, 2015, Page(s) 330-340, ISSN 1549-3296
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/jbm.a.35178

Book chapters (2)

Interfollicular Epidermal Stem Cells: Boosting and Rescuing from Adult Skin

Auteurs: Mariana T. Cerqueira, Ana M. Frias, Rui L. Reis, Alexandra P. Marques
Publié dans: Skin Stem Cells, 2013, Page(s) 1-9, ISBN 978-1-62703-330-5
Éditeur: Humana Press
DOI: 10.1007/978-1-62703-330-5_1

Interfollicular Epidermal Stem Cells: Boosting and Rescuing from Adult Skin

Auteurs: Mariana T. Cerqueira, Ana M. Frias, Rui L. Reis, Alexandra P. Marques
Publié dans: Skin Stem Cells, 2013, Page(s) 1-9, ISBN 978-1-62703-330-5
Éditeur: Humana Press
DOI: 10.1007/978-1-62703-330-5_1

Droits de propriété intellectuelle

Patent (1)

FIBERS WITH SEGMENTS, THEIR PREPARATION AND APPLICATIONS THEREOF

Numéro de demande/publication: PCT IB2017/056654
Date: 2017-10-26
Demandeur(s): UNIVERSIDADE DO MINHO