Gene2Skin - Roadmap for advanced genetic engineering-based skin therapies

Informacje na temat projektu

Gene2Skin

Identyfikator umowy o grant: 692221

DOI

10.3030/692221

Projekt został zamknięty

Data podpisania przez KE 6 Listopada 2015

Data rozpoczęcia 1 Grudnia 2015

Data zakończenia 30 Listopada 2018

Finansowanie w ramach

• SPREADING EXCELLENCE AND WIDENING PARTICIPATION

Koszt całkowity

€ 992 068,75

Wkład UE

€ 992 068,75

Koordynowany przez

UNIVERSIDADE DO MINHO
Portugal

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (9)

Report on the dissemination of the project activities to the general public

A report on the dissemination of the project activities and outcomes to the general public will be made.

Report on gender representation on the activities of the project

A report on gender representation on the activities of the project will be performed

Statement of completion of task 4.6

Statement of completion of task 3.6

Report on the dissemination of the project activities to industrial players and investors

A report on the dissemination of the project activities to industrial players and investors and respective feedback will be performed.

Report on the organized workshops

A report will be made on the workshops organized by RCSI and KCL

Report on the dissemination of the project outcomes to patients and clinicians

Report on the dissemination of the project outcomes to patients and clinicians.

Reports on dissemination of the project in the scientific community

Report on the dissemination of the project outcomes to the scientific community will be peformed.

Report on the Project retreat, international conferences and summer schools

A report on several activities organized in the scope of the project will be made, namely on the project retreat, on the jointly organized international conferences and on the summer schools organized by UMINHO.

Report on the outreach of project activities to the regulatory authorities

A report on the outreach of project activities to the regulatory authorities and organizations will be performed.

Websites, patent fillings, videos etc. (1)

Website and newsletter creation

A website and a periodic newsletter will be created and periodically released.

Publikacje

Peer reviewed articles (19)

Poly(hydroxybutyrate- co -hydroxyvalerate) Bilayer Skin Tissue Engineering Constructs with Improved Epidermal Rearrangement

Autorzy: Alessandra Zonari, Mariana T. Cerqueira, Silviene Novikoff, Alfredo M. Goes, Alexandra P. Marques, Vitor M. Correlo, Rui L. Reis
Opublikowane w: Macromolecular Bioscience, Numer 14/7, 2014, Strona(/y) 977-990, ISSN 1616-5187
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.201400005

Gellan Gum-Hyaluronic Acid Spongy-like Hydrogels and Cells from Adipose Tissue Synergize Promoting Neoskin Vascularization

Autorzy: Mariana Teixeira Cerqueira, Lucília Pereira da Silva, Tírcia Carlos Santos, Rogério Pedro Pirraco, Vítor Manuel Correlo, Rui Luís Reis, Alexandra Pinto Marques
Opublikowane w: ACS Applied Materials & Interfaces, Numer 6/22, 2014, Strona(/y) 19668-19679, ISSN 1944-8244
Wydawca: American Chemical Society
DOI: 10.1021/am504520j

Human Skin Cell Fractions Fail to Self-Organize Within a Gellan Gum/Hyaluronic Acid Matrix but Positively Influence Early Wound Healing

Autorzy: Mariana T. Cerqueira, Lucília P. da Silva, Tírcia C. Santos, Rogério P. Pirraco, Vitor M. Correlo, Alexandra P. Marques, Rui L. Reis
Opublikowane w: Tissue Engineering Part A, Numer 20/9-10, 2014, Strona(/y) 1369-1378, ISSN 1937-3341
Wydawca: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tea.2013.0460

Human Adipose Stem Cells Cell Sheet Constructs Impact Epidermal Morphogenesis in Full-Thickness Excisional Wounds

Autorzy: M. T. Cerqueira, R. P. Pirraco, T. C. Santos, D. B. Rodrigues, A. M. Frias, A. R. Martins, R. L. Reis, A. P. Marques
Opublikowane w: Biomacromolecules, Numer 14/11, 2013, Strona(/y) 3997-4008, ISSN 1525-7797
Wydawca: American Chemical Society
DOI: 10.1021/bm4011062

A two-component pre-seeded dermal–epidermal scaffold

Autorzy: I.P. Monteiro, D. Gabriel, B.P. Timko, M. Hashimoto, S. Karajanagi, R. Tong, A.P. Marques, R.L. Reis, D.S. Kohane
Opublikowane w: Acta Biomaterialia, Numer 10/12, 2014, Strona(/y) 4928-4938, ISSN 1742-7061
Wydawca: Elsevier BV
DOI: 10.1016/j.actbio.2014.08.029

Cell sheet technology-driven re-epithelialization and neovascularization of skin wounds

Autorzy: M.T. Cerqueira, R.P. Pirraco, A.R. Martins, T.C. Santos, R.L. Reis, A.P. Marques
Opublikowane w: Acta Biomaterialia, Numer 10/7, 2014, Strona(/y) 3145-3155, ISSN 1742-7061
Wydawca: Elsevier BV
DOI: 10.1016/j.actbio.2014.03.006

Boosting and Rescuing Epidermal Superior Population from Fresh Keratinocyte Cultures

Autorzy: Mariana T. Cerqueira, Ana M. Frias, Rui L. Reis, Alexandra P. Marques
Opublikowane w: Stem Cells and Development, Numer 23/1, 2014, Strona(/y) 34-43, ISSN 1547-3287
Wydawca: Mary Ann Liebert Inc.
DOI: 10.1089/scd.2013.0038

Stem Cell-Containing Hyaluronic Acid-Based Spongy Hydrogels for Integrated Diabetic Wound Healing

Autorzy: Lucília Pereira da Silva, Tírcia Carlos Santos, Daniel Barreira Rodrigues, Rogério Pedro Pirraco, Mariana Teixeira Cerqueira, Rui Luís Reis, Vitor Manuel Correlo, Alexandra Pinto Marques
Opublikowane w: Journal of Investigative Dermatology, Numer 137/7, 2017, Strona(/y) 1541-1551, ISSN 0022-202X
Wydawca: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2017.02.976

Spray-assisted layer-by-layer assembly on hyaluronic acid scaffolds for skin tissue engineering

Autorzy: Isa P. Monteiro, Anita Shukla, Alexandra P. Marques, Rui L. Reis, Paula T. Hammond
Opublikowane w: Journal of Biomedical Materials Research Part A, Numer 15493296, 2015, Strona(/y) 330-340, ISSN 1549-3296
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/jbm.a.35178

Boosting and Rescuing Epidermal Superior Population from Fresh Keratinocyte Cultures

Autorzy: Mariana T. Cerqueira, Ana M. Frias, Rui L. Reis, Alexandra P. Marques
Opublikowane w: Stem Cells and Development, Numer 15473287, 2014, Strona(/y) 34-43, ISSN 1547-3287
Wydawca: Mary Ann Liebert Inc.
DOI: 10.1089/scd.2013.0038

Epidermis recreation in spongy-like hydrogels

Autorzy: M.T. Cerqueira, L.P. da Silva, V.M. Correlo, R.L. Reis, A.P. Marques
Opublikowane w: Materials Today, Numer 13697021, 2015, Strona(/y) 468-469, ISSN 1369-7021
Wydawca: Elsevier BV
DOI: 10.1016/j.mattod.2015.08.018

Cell sheet technology-driven re-epithelialization and neovascularization of skin wounds

Autorzy: M.T. Cerqueira, R.P. Pirraco, A.R. Martins, T.C. Santos, R.L. Reis, A.P. Marques
Opublikowane w: Acta Biomaterialia, Numer 17427061, 2014, Strona(/y) 3145-3155, ISSN 1742-7061
Wydawca: Elsevier BV
DOI: 10.1016/j.actbio.2014.03.006

A two-component pre-seeded dermal–epidermal scaffold

Autorzy: I.P. Monteiro, D. Gabriel, B.P. Timko, M. Hashimoto, S. Karajanagi, R. Tong, A.P. Marques, R.L. Reis, D.S. Kohane
Opublikowane w: Acta Biomaterialia, Numer 17427061, 2014, Strona(/y) 4928-4938, ISSN 1742-7061
Wydawca: Elsevier BV
DOI: 10.1016/j.actbio.2014.08.029

Gellan Gum-Hyaluronic Acid Spongy-like Hydrogels and Cells from Adipose Tissue Synergize Promoting Neoskin Vascularization

Autorzy: Mariana Teixeira Cerqueira, Lucília Pereira da Silva, Tírcia Carlos Santos, Rogério Pedro Pirraco, Vítor Manuel Correlo, Rui Luís Reis, Alexandra Pinto Marques
Opublikowane w: ACS Applied Materials & Interfaces, Numer 19448244, 2014, Strona(/y) 19668-19679, ISSN 1944-8244
Wydawca: American Chemical Society
DOI: 10.1021/am504520j

Human Skin Cell Fractions Fail to Self-Organize Within a Gellan Gum/Hyaluronic Acid Matrix but Positively Influence Early Wound Healing

Autorzy: Mariana T. Cerqueira, Lucília P. da Silva, Tírcia C. Santos, Rogério P. Pirraco, Vitor M. Correlo, Alexandra P. Marques, Rui L. Reis
Opublikowane w: Tissue Engineering Part A, Numer 19373341, 2014, Strona(/y) 1369-1378, ISSN 1937-3341
Wydawca: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tea.2013.0460

Poly(hydroxybutyrate- co -hydroxyvalerate) Bilayer Skin Tissue Engineering Constructs with Improved Epidermal Rearrangement

Autorzy: Alessandra Zonari, Mariana T. Cerqueira, Silviene Novikoff, Alfredo M. Goes, Alexandra P. Marques, Vitor M. Correlo, Rui L. Reis
Opublikowane w: Macromolecular Bioscience, Numer 16165187, 2014, Strona(/y) 977-990, ISSN 1616-5187
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.201400005

Human Adipose Stem Cells Cell Sheet Constructs Impact Epidermal Morphogenesis in Full-Thickness Excisional Wounds

Autorzy: M. T. Cerqueira, R. P. Pirraco, T. C. Santos, D. B. Rodrigues, A. M. Frias, A. R. Martins, R. L. Reis, A. P. Marques
Opublikowane w: Biomacromolecules, Numer 15257797, 2013, Strona(/y) 3997-4008, ISSN 1525-7797
Wydawca: American Chemical Society
DOI: 10.1021/bm4011062

Epidermis recreation in spongy-like hydrogels

Autorzy: M.T. Cerqueira, L.P. da Silva, V.M. Correlo, R.L. Reis, A.P. Marques
Opublikowane w: Materials Today, Numer 18/8, 2015, Strona(/y) 468-469, ISSN 1369-7021
Wydawca: Elsevier BV
DOI: 10.1016/j.mattod.2015.08.018

Spray-assisted layer-by-layer assembly on hyaluronic acid scaffolds for skin tissue engineering

Autorzy: Isa P. Monteiro, Anita Shukla, Alexandra P. Marques, Rui L. Reis, Paula T. Hammond
Opublikowane w: Journal of Biomedical Materials Research Part A, Numer 103/1, 2015, Strona(/y) 330-340, ISSN 1549-3296
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/jbm.a.35178

Book chapters (2)

Interfollicular Epidermal Stem Cells: Boosting and Rescuing from Adult Skin

Autorzy: Mariana T. Cerqueira, Ana M. Frias, Rui L. Reis, Alexandra P. Marques
Opublikowane w: Skin Stem Cells, 2013, Strona(/y) 1-9, ISBN 978-1-62703-330-5
Wydawca: Humana Press
DOI: 10.1007/978-1-62703-330-5_1

Interfollicular Epidermal Stem Cells: Boosting and Rescuing from Adult Skin

Autorzy: Mariana T. Cerqueira, Ana M. Frias, Rui L. Reis, Alexandra P. Marques
Opublikowane w: Skin Stem Cells, 2013, Strona(/y) 1-9, ISBN 978-1-62703-330-5
Wydawca: Humana Press
DOI: 10.1007/978-1-62703-330-5_1

Prawa własności intelektualnej

Patent (1)

FIBERS WITH SEGMENTS, THEIR PREPARATION AND APPLICATIONS THEREOF

Numer wniosku/publikacji: PCT IB2017/056654
Data: 2017-10-26
Wnioskodawca/wnioskodawcy: UNIVERSIDADE DO MINHO