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Gene2Skin - Roadmap for advanced genetic engineering-based skin therapies

Resultado final

Report on the dissemination of the project activities to the general public

A report on the dissemination of the project activities and outcomes to the general public will be made.

Report on gender representation on the activities of the project

A report on gender representation on the activities of the project will be performed

Statement of completion of task 4.6

Statement of completion of task 3.6

Report on the dissemination of the project activities to industrial players and investors

A report on the dissemination of the project activities to industrial players and investors and respective feedback will be performed.

Report on the organized workshops

A report will be made on the workshops organized by RCSI and KCL

Report on the dissemination of the project outcomes to patients and clinicians

Report on the dissemination of the project outcomes to patients and clinicians.

Reports on dissemination of the project in the scientific community

Report on the dissemination of the project outcomes to the scientific community will be peformed.

Report on the Project retreat, international conferences and summer schools

A report on several activities organized in the scope of the project will be made, namely on the project retreat, on the jointly organized international conferences and on the summer schools organized by UMINHO.

Report on the outreach of project activities to the regulatory authorities

A report on the outreach of project activities to the regulatory authorities and organizations will be performed.

Website and newsletter creation

A website and a periodic newsletter will be created and periodically released.

Publicaciones

Stem Cell-Containing Hyaluronic Acid-Based Spongy Hydrogels for Integrated Diabetic Wound Healing

Autores: Lucília Pereira da Silva, Tírcia Carlos Santos, Daniel Barreira Rodrigues, Rogério Pedro Pirraco, Mariana Teixeira Cerqueira, Rui Luís Reis, Vitor Manuel Correlo, Alexandra Pinto Marques
Publicado en: Journal of Investigative Dermatology, 137/7, 2017, Page(s) 1541-1551, ISSN 0022-202X
Editor: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2017.02.976

Spray-assisted layer-by-layer assembly on hyaluronic acid scaffolds for skin tissue engineering

Autores: Isa P. Monteiro, Anita Shukla, Alexandra P. Marques, Rui L. Reis, Paula T. Hammond
Publicado en: Journal of Biomedical Materials Research Part A, 103/1, 2015, Page(s) 330-340, ISSN 1549-3296
Editor: John Wiley & Sons Inc.
DOI: 10.1002/jbm.a.35178

Boosting and Rescuing Epidermal Superior Population from Fresh Keratinocyte Cultures

Autores: Mariana T. Cerqueira, Ana M. Frias, Rui L. Reis, Alexandra P. Marques
Publicado en: Stem Cells and Development, 23/1, 2014, Page(s) 34-43, ISSN 1547-3287
Editor: Mary Ann Liebert Inc.
DOI: 10.1089/scd.2013.0038

Epidermis recreation in spongy-like hydrogels

Autores: M.T. Cerqueira, L.P. da Silva, V.M. Correlo, R.L. Reis, A.P. Marques
Publicado en: Materials Today, 18/8, 2015, Page(s) 468-469, ISSN 1369-7021
Editor: Elsevier BV
DOI: 10.1016/j.mattod.2015.08.018

Cell sheet technology-driven re-epithelialization and neovascularization of skin wounds

Autores: M.T. Cerqueira, R.P. Pirraco, A.R. Martins, T.C. Santos, R.L. Reis, A.P. Marques
Publicado en: Acta Biomaterialia, 10/7, 2014, Page(s) 3145-3155, ISSN 1742-7061
Editor: Elsevier BV
DOI: 10.1016/j.actbio.2014.03.006

A two-component pre-seeded dermal–epidermal scaffold

Autores: I.P. Monteiro, D. Gabriel, B.P. Timko, M. Hashimoto, S. Karajanagi, R. Tong, A.P. Marques, R.L. Reis, D.S. Kohane
Publicado en: Acta Biomaterialia, 10/12, 2014, Page(s) 4928-4938, ISSN 1742-7061
Editor: Elsevier BV
DOI: 10.1016/j.actbio.2014.08.029

Gellan Gum-Hyaluronic Acid Spongy-like Hydrogels and Cells from Adipose Tissue Synergize Promoting Neoskin Vascularization

Autores: Mariana Teixeira Cerqueira, Lucília Pereira da Silva, Tírcia Carlos Santos, Rogério Pedro Pirraco, Vítor Manuel Correlo, Rui Luís Reis, Alexandra Pinto Marques
Publicado en: ACS Applied Materials & Interfaces, 6/22, 2014, Page(s) 19668-19679, ISSN 1944-8244
Editor: American Chemical Society
DOI: 10.1021/am504520j

Human Skin Cell Fractions Fail to Self-Organize Within a Gellan Gum/Hyaluronic Acid Matrix but Positively Influence Early Wound Healing

Autores: Mariana T. Cerqueira, Lucília P. da Silva, Tírcia C. Santos, Rogério P. Pirraco, Vitor M. Correlo, Alexandra P. Marques, Rui L. Reis
Publicado en: Tissue Engineering Part A, 20/9-10, 2014, Page(s) 1369-1378, ISSN 1937-3341
Editor: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tea.2013.0460

Poly(hydroxybutyrate- co -hydroxyvalerate) Bilayer Skin Tissue Engineering Constructs with Improved Epidermal Rearrangement

Autores: Alessandra Zonari, Mariana T. Cerqueira, Silviene Novikoff, Alfredo M. Goes, Alexandra P. Marques, Vitor M. Correlo, Rui L. Reis
Publicado en: Macromolecular Bioscience, 14/7, 2014, Page(s) 977-990, ISSN 1616-5187
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.201400005

Human Adipose Stem Cells Cell Sheet Constructs Impact Epidermal Morphogenesis in Full-Thickness Excisional Wounds

Autores: M. T. Cerqueira, R. P. Pirraco, T. C. Santos, D. B. Rodrigues, A. M. Frias, A. R. Martins, R. L. Reis, A. P. Marques
Publicado en: Biomacromolecules, 14/11, 2013, Page(s) 3997-4008, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/bm4011062

Interfollicular Epidermal Stem Cells: Boosting and Rescuing from Adult Skin

Autores: Mariana T. Cerqueira, Ana M. Frias, Rui L. Reis, Alexandra P. Marques
Publicado en: Skin Stem Cells, 2013, Page(s) 1-9, ISBN 978-1-62703-330-5
Editor: Humana Press
DOI: 10.1007/978-1-62703-330-5_1