Objective
Various pathologies directly impede the conduction of sound through the human middle ear, and thereby produce a ‘conductive’ hearing loss which is the second most prevalent health issue globally. According to Hearing Health Foundation more than 360 million people suffer from hearing disorders worldwide. Hearing depends on a series of events that change sound waves in the air into electrical signals. Sounds that travel down the ear canal set the surface of the flexible eardrum or tympanic membrane (TM) into rapid pico- to nanometer scale vibrations. These motions are coupled to the inner ear by the ossicular chain (the malleus, incus, and stapes). Since the TM and ossicular chain are the primary portal through which acoustic stimuli reach the inner ear, pathological changes in the TM or ossicular chain result in conductive hearing losses. Accurate diagnosis of middle-ear diseases is critical to effective and timely treatments of hearing loss. No currently available clinical technique is capable of simultaneously visualizing and quantifying the structure and sound-induced vibration of the middle ear in vivo. Recently, a new functional imaging technique based on optical coherence tomography (OCT) and the principle of vibrography for middle ear imaging was demonstrated. In this method, termed OCT-vibrography, a speaker is used to excite acoustic vibration in the tissue, and the resulting tissue displacement is captured by OCT. The goal of this project is to make for the first time a miniaturized OCT-vibrography probe for middle ear imaging at high frequencies. The miniaturized probe will be designed through integrated optics which will enable high-speed imaging. The system will operate in two modes: static imaging mode for examining biofilms and ear infections behind the ear drum; dynamic imaging mode for capturing high frequency (up to 20 kHz) oscillations in the middle ear structures. The operation of the miniaturized probes will be validated on ex vivo specimens.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2015
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
1081 HV Amsterdam
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.