Biomedical Engineering and Medical Physics

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Pubblicazioni

Paradoxical Rules of Spike Train Decoding Revealed at the Sensitivity Limit of Vision

Autori: Smeds, Lina; Takeshita, Daisuke; Turunen, Tuomas; Tiihonen, Jussi; Westö, Johan; Martyniuk, Nataliia; Seppänen, Aarni; Ala-Laurila, Petri
Pubblicato in: Neuron, Numero 104, 2019, Pagina/e 576-587, ISSN 0896-6273
Editore: Cell Press
DOI: 10.1016/j.neuron.2019.08.005

Mineralization of dental tissues and caries lesions detailed with Raman microspectroscopic imaging

Autori: Shuvashis Das Gupta; Markus Killenberger; Tarja Tanner; Tarja Tanner; Lassi Rieppo; Simo Saarakkala; Simo Saarakkala; Jarkko Heikkilä; Vuokko Anttonen; Vuokko Anttonen; Mikko A. J. Finnilä
Pubblicato in: Analyst, Numero 146, 2021, Pagina/e 1705-1713, ISSN 0003-2654
Editore: Royal Society of Chemistry
DOI: 10.1039/d0an01938k

EMG-Assisted Muscle Force Driven Finite Element Model of the Knee Joint with Fibril-Reinforced Poroelastic Cartilages and Menisci

Autori: Esrafilian, A.; Stenroth, L.; Mononen, M. E.; Tanska, P.; Avela, J.; Korhonen, R. K.
Pubblicato in: Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020), Numero 10, 2020, Pagina/e 1-16, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-020-59602-2

Experimental mechanical strain measurement of tissues

Autori: Lingwei Huang; Rami K. Korhonen; Mikael J. Turunen; Mikko A. J. Finnilä; Mikko A. J. Finnilä; Mikko A. J. Finnilä
Pubblicato in: PeerJ, Vol 7, p e6545 (2019), Numero 7, 2019, Pagina/e e6545, ISSN 2167-8359
Editore: PeerJ
DOI: 10.7717/peerj.6545

Characterizing Aptamers with Reconfigurable Chiral Plasmonic Assemblies

Autori: Huang Y., Nguyen M., Nguyen H., Loo J., Lehtonen A., Kuzyk A
Pubblicato in: Langmuir, Numero 38, 2022, Pagina/e 2954-2960, ISSN 0743-7463
Editore: American Chemical Society
DOI: 10.1021/acs.langmuir.1c03434

Calibration and validation of accelerometer-based activity monitors: A systematic review of machine-learning approaches

Autori: Farrahi V., Niemelä M., Kangas M., Korpelainen R., Jämsä T.
Pubblicato in: Gait and Posture, Numero 68, 2019, Pagina/e 285-299, ISSN 0966-6362
Editore: Elsevier BV
DOI: 10.1016/j.gaitpost.2018.12.003

Compositional associations of sleep and activities within the 24-h cycle with cardiometabolic health markers in adults

Autori: Farrahi V., Kangas M., Walmsley R., Niemelä M., Kiviniemi A., Puukka K., Collings P.J., Korpelainen R., Jämsä T.
Pubblicato in: Medicine & Science in Sports & Exercise, Numero 53, 2021, Pagina/e 324-332, ISSN 0195-9131
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1249/mss.0000000000002481

Intensity and temporal patterns of physical activity and cardiovascular disease risk in midlife

Autori: Niemelä, Maisa; Kangas, Maarit; Farrahi, Vahid; Kiviniemi, Antti; Leinonen, Anna-Maiju; Ahola, Riikka; Puukka, Katri; Auvinen, Juha; Korpelainen, Raija; Jämsä, Timo
Pubblicato in: Preventive Medicine, Numero 124, 2019, Pagina/e 33-41, ISSN 0091-7435
Editore: Academic Press
DOI: 10.1016/j.ypmed.2019.04.023

Accumulation patterns of sedentary time and breaks and their association with cardiometabolic health markers in adults

Autori: Farrahi, V. (Vahid); Kangas, M. (Maarit); Kiviniemi, A. (Antti); Puukka, K. (Katri); Korpelainen, R. (Raija); Jämsä, T. (Timo)
Pubblicato in: The Scandinavian Journal of Medicine & Science in Sports, Numero 31, 2021, Pagina/e 1489–1507, ISSN 0905-7188
Editore: Blackwell Publishing Inc.
DOI: 10.1111/sms.13958

Fracture strength of the proximal femur injected with a calcium sulfate/hydroxyapatite bone substitute.

Autori: Kok J., Širka A., Grassi L., Raina D.B., Tarasevičius Š., Tägil M., Lidgren L., Isaksson H.
Pubblicato in: Clinical Biomechanics, Numero 63, 2019, Pagina/e 172-178, ISSN 0268-0033
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.clinbiomech.2019.03.008

Augmenting a dynamic hip screw with a calcium sulfate/hydroxyapatite biomaterial.

Autori: Kok J., Širka A., Liu Y., Tarasevičius, Belickas J., Tägil M., Lidgren L., Isaksson H., Raina D.B.
Pubblicato in: Medical Engineering & Physics, Numero 92, 2021, Pagina/e 102-109, ISSN 1350-4533
Editore: Elsevier BV
DOI: 10.1016/j.medengphy.2021.05.006

Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates

Autori: Huang, Yike; Nguyen; Kha; Kuzyk, Anton
Pubblicato in: Journal of visualized experiments, Numero 145, 2019, Pagina/e 1-8, ISSN 1940-087X
Editore: MYJoVE Corporation
DOI: 10.3791/59280

Hyaluronan derived nanoparticle for simvastatin delivery: evaluation of simvastatin induced myotoxicity in tissue engineered skeletal muscle.

Autori: Jones, Julia M.; Player, Darren J.; Samanta, Sumanta; Rangasami, Vignesh K.; Hilborn, Jöns; Lewis, Mark P.; Oommen, Oommen P.; Mudera, Vivek
Pubblicato in: Biomaterials Science, Numero 8, 2020, Pagina/e 302-331, ISSN 2047-4830
Editore: Royal Society of Chemistry
DOI: 10.1039/c9bm00986h

Predicting overall survival time in glioblastoma patients using gradient boosting machines algorithm and recursive feature elimination technique

Autori: Karami G., Orlando M.G., Pizzi A.D., Caulo M., Gratta C.D.
Pubblicato in: Cancers, Numero 13, 2021, Pagina/e 4976, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13194976

Pluronic Micelle-Mediated Tissue Factor Silencing Enhances Hemocompatibility, Stemness, Differentiation Potential, and Paracrine Signaling of Mesenchymal Stem Cells.

Autori: Vignesh K. Rangasami; Ganesh N. Nawale; Kenta Asawa; Sandeep Kadekar; Sumanta Samanta; Bo Nilsson; Kristina Nilsson Ekdahl; Kristina Nilsson Ekdahl; Susanna Miettinen; Jöns Hilborn; Yuji Teramura; Yuji Teramura; Oommen P. Varghese; Oommen P. Oommen
Pubblicato in: Biomacromolecules, Numero 22/5, 2021, Pagina/e 1980-1989, ISSN 1525-7797
Editore: American Chemical Society
DOI: 10.1021/acs.biomac.1c00070

Astrocytes exhibit a protective role on neuronal firing patterns under chemically-induced seizures in neuron-astrocyte co-cultures

Autori: Ahtiainen A., Genocchi B., Tanskanen J.M.A., Barros M.T., Hyttinen J.A.K., Lenk K.
Pubblicato in: International Journal of Molecular Sciences, Numero 22, 2021, Pagina/e 12770, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms222312770

Mechanobiological model for simulation of injured cartilage degradation via pro-inflammatory cytokines and mechanical stimulus

Autori: Eskelinen A.S.A., Tanska P., Florea C., Orozco G.A., Julkunen P., Grodzinsky A.J., Korhonen R.K.
Pubblicato in: PLoS computational biology, Numero 6, 2020, Pagina/e 1007998, ISSN 1553-734X
Editore: Public Library of Science
DOI: 10.1371/journal.pcbi.1007998

Toward Tailored Rehabilitation by Implementation of a Novel Musculoskeletal Finite Element Analysis Pipeline.

Autori: Esrafilian A, Stenroth L, Mononen ME, Vartiainen P, Tanska P, Karjalainen PA, Suomalainen JS, Arokoski JPA, Saxby DJ, Lloyd DG, Korhonen RK
Pubblicato in: IEEE Transactions on Neural Systems and Rehabilitation Engineering, Numero 30, 2022, Pagina/e 789-802, ISSN 1534-4320
Editore: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tnsre.2022.3159685

A DNA Origami-Based Chiral Plasmonic Sensing Device

Autori: Huang, Y., Nguyen, M.-K., Natarajan, A.K., Nguyen, V.H., Kuzyk, A.
Pubblicato in: ACS Applied Materials and Interfaces, Numero 10, 2018, Pagina/e 44221-44225, ISSN 1944-8244
Editore: American Chemical Society
DOI: 10.1021/acsami.8b19153

An unexpected role of an extra phenolic hydroxyl on the chemical reactivity and bioactivity of catechol or gallol modified hyaluronic acid hydrogels

Autori: Sumanta Samanta; Vignesh K. Rangasami; N. Arul Murugan; Vijay Singh Parihar; Oommen P. Varghese; Oommen P. Oommen
Pubblicato in: Polymer Chemistry, Numero 12, 2021, Pagina/e 2987-2991, ISSN 1759-9954
Editore: Royal Society of Chemistry
DOI: 10.1039/d1py00013f

Subchondral bone plate thickness is associated with micromechanical and microstructural changes in the bovine patella osteochondral junction with different levels of cartilage degeneration.

Autori: Das Gupta S., Workman J., Finnilä M.A.J., Saarakkala S., Thambyah A.
Pubblicato in: Journal of the Mechanical Behavior of Biomedical Materials, Numero 129, 2022, Pagina/e 105158, ISSN 1751-6161
Editore: Elsevier BV
DOI: 10.1016/j.jmbbm.2022.105158

Evaluating and Enhancing the Generalization Performance of Machine Learning Models for Physical Activity Intensity Prediction From Raw Acceleration Data

Autori: Farrahi, Vahid; Niemela, Maisa; Tjurin, Petra; Kangas, Maarit; Korpelainen, Raija; Jamsa, Timo
Pubblicato in: IEEE Journal of Biomedical and Health Informatics, Numero 24, 2020, Pagina/e 27-38, ISSN 2168-2194
Editore: Institute of Electrical and Electronics Engineers Inc.
DOI: 10.1109/jbhi.2019.2917565

Harnessing hyaluronic acid-based nanoparticles for combination therapy: A novel approach for suppressing systemic inflammation and to promote antitumor macrophage polarization.

Autori: Vignesh K. Rangasami; Sumanta Samanta; Vijay Singh Parihar; Kenta Asawa; Keying Zhu; Oommen P. Varghese; Yuji Teramura; Yuji Teramura; Bo Nilsson; Jöns Hilborn; Robert A. Harris; Oommen P. Oommen
Pubblicato in: Carbohydrate Polymers, Numero 254, 2020, Pagina/e 117291, ISSN 0144-8617
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.carbpol.2020.117291

Femoral strength and strains in sideways fall: Validation of finite element models against bilateral strain measurements

Autori: Kok J., Grassi L., Gustafsson A., Isaksson H.
Pubblicato in: Journal of Biomechanics, Numero 122, 2021, Pagina/e 110445, ISSN 0021-9290
Editore: Elsevier BV
DOI: 10.1016/j.jbiomech.2021.110445

Decoding working memory task condition using magnetoencephalography source level long-range phase coupling patterns.

Autori: Jaakko Johannes Syrjälä; Alessio Basti; Roberto Guidotti; Laura Marzetti; Vittorio Pizzella
Pubblicato in: Journal of Neural Engineering, Numero 18, 2021, Pagina/e 016027, ISSN 1741-2560
Editore: Institute of Physics Publishing
DOI: 10.1088/1741-2552/abcefe

Prediction of local fixed charge density loss in cartilage following ACL injury and reconstruction: A computational proof-of-concept study with MRI follow-up

Autori: Orozco G.A., Bolcos P., Mohammadi A., Tanaka M.S., Yang M., Link T.M., Ma B., Li X., Tanska P., Korhonen R.K.
Pubblicato in: Journal of Orthopaedic Research, Numero 39, 2020, Pagina/e 1064-1081, ISSN 0736-0266
Editore: Elsevier BV
DOI: 10.1002/jor.24797

A numerical framework for mechano-regulated tendon healing-Simulation of early regeneration of the Achilles tendon

Autori: Notermans T., Tanska P., Korhonen R.K., Khayyeri H., Isaksson H.
Pubblicato in: Plos Computational Biology, Numero 17, 2021, Pagina/e e1008636, ISSN 1553-734X
Editore: Public Library of Science
DOI: 10.1371/journal.pcbi.1008636

Raman microspectroscopic analysis of the tissue-specific composition of the human osteochondral junction in osteoarthritis:a pilot study

Autori: Das Gupta, S. (Shuvashis); Finnilä, M. A. (Mikko A.J.); Karhula, S. S. (Sakari S.); Kauppinen, S. (Sami); Joukainen, A. (Antti); Kröger, H. (Heikki); Korhonen, R. K. (Rami K.); Thambyah, A. (Ashvin); Rieppo, L. (Lassi); Saarakkala, S. (Simo)
Pubblicato in: Acta Biomaterialia, Numero 106, 2020, Pagina/e 145-155, ISSN 1742-7061
Editore: Elsevier BV

Larger Connection Radius Increases Hub Astrocyte Number in a 3-D Neuron–Astrocyte Network Model

Autori: Kerstin Lenk; Barbara Genocchi; Michael Taynnan Barros; Jari Hyttinen
Pubblicato in: IEEE Transactions on Molecular, Biological and Multi-Scale Communications, Numero 7, 2021, Pagina/e 83-88, ISSN 2332-7804
Editore: Institute of Electrical and Electronics Engineers Inc.
DOI: 10.1109/tmbmc.2021.3054890

Correlates of physical activity behavior in adults : a data mining approach

Autori: Farrahi V., Niemelä M., Kärmeniemi M., Puhakka S., Kangas M., Korpelainen R., Jämsä T.
Pubblicato in: International journal of behavioral nutrition and physical activity, Numero 17, 2020, Pagina/e 94, ISSN 1479-5868
Editore: BioMed Central
DOI: 10.1186/s12966-020-00996-7

Automated analysis of rabbit knee calcified cartilage morphology using micro-computed tomography and deep learning.

Autori: Santeri J. O. Rytky; Lingwei Huang; Petri Tanska; Aleksei Tiulpin; Aleksei Tiulpin; Egor Panfilov; Walter Herzog; Rami K. Korhonen; Simo Saarakkala; Simo Saarakkala; Mikko A. J. Finnilä; Mikko A. J. Finnilä; Mikko A. J. Finnilä
Pubblicato in: Journal of Anatomy, Numero 239/2, 2021, Pagina/e 251-263, ISSN 0021-8782
Editore: Blackwell Publishing Inc.
DOI: 10.1111/joa.13435

An EMG-assisted muscle-force driven finite element analysis pipeline to investigate joint- and tissue-level mechanical responses in functional activities: towards a rapid assessment toolbox

Autori: Esrafilian A, Stenroth L, Mononen ME, Vartiainen PEJ, Tanska P, Karjalainen PA, Suomalainen JS, Arokoski JPA, Saxby D, Lloyd DG, Korhonen RK
Pubblicato in: IEEE Transactions on Bio-medical Engineering, 2022, ISSN 0018-9294
Editore: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tbme.2022.3156018

Prolonged bouts of sedentary time and cardiac autonomic function in midlife

Autori: Niemelä M., Kiviniemi A., Kangas M., Farrahi V., Leinonen A., Ahola R., Tammelin T., Auvinen J., Korpelainen R., Jämsä T.
Pubblicato in: Translational Sports Medicine, Numero 2, 2019, Pagina/e 341-350, ISSN 2573-8488
Editore: John Wiley & Sons
DOI: 10.1002/tsm2.100

http://urn.fi/urn:nbn:fi-fe202201031034

Autori: Huang L., Riihioja I., Tanska P., Ojanen S., Palosaari S., Kröger H., Saarakkala S.J., Herzog W., Korhonen R.K., Finnilä M.A.J.
Pubblicato in: Journal of orthopaedic research, Numero 39, 2022, Pagina/e 2556 - 2567, ISSN 0736-0266
Editore: Elsevier BV
DOI: 10.1002/jor.25009

The effect of constitutive representations and structural constituents of ligaments on knee joint mechanics

Autori: Gustavo A. Orozco, Petri Tanska, Mika E. Mononen, Kimmo S. Halonen, Rami K. Korhonen
Pubblicato in: Scientific Reports, Numero 8/1, 2018, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-018-20739-w

A novel mechanobiological model can predict how physiologically relevant dynamic loading causes proteoglycan loss in mechanically injured articular cartilage.

Autori: Orozco, Gustavo A.; Tanska, Petri; Florea, Cristina; Grodzinsky, Alan J.; Korhonen, Rami K.
Pubblicato in: Scientific Reports, Numero 8, 2018, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-018-33759-3

Shear strain and inflammation-induced fixed charge density loss in the knee joint cartilage following ACL injury and reconstruction: A computational study

Autori: Orozco G.A., Eskelinen A.S.A., Kosonen J.P., Tanaka M.S., Yang M., Link T.M., Ma B., Li X., Grodzinsky A.J., Korhonen R.K., Tanska P.
Pubblicato in: Journal of orthopaedic research, 2021, ISSN 0736-0266
Editore: Elsevier BV
DOI: 10.1002/jor.25177

Machine-learning models for activity class prediction : a comparative study of feature selection and classification algorithms

Autori: Chong J, Tjurin P, Niemelä M, Jämsä T, Farrahi V.
Pubblicato in: Gait & posture, Numero 89, 2021, Pagina/e 45-53, ISSN 0966-6362
Editore: Elsevier BV
DOI: 10.1016/j.gaitpost.2021.06.017

Brain Functional Connectivity Through Phase Coupling of Neuronal Oscillations: A Perspective From Magnetoencephalography.

Autori: Laura Marzetti; Laura Marzetti; Alessio Basti; Alessio Basti; Federico Chella; Federico Chella; Antea D'Andrea; Antea D'Andrea; Jaakko Syrjälä; Jaakko Syrjälä; Vittorio Pizzella; Vittorio Pizzella
Pubblicato in: Frontiers in Neuroscience, Vol 13 (2019), Numero 13, 2019, Pagina/e 964, ISSN 1662-4548
Editore: Frontiers Research Foundation
DOI: 10.3389/fnins.2019.00964

12 Degrees of Freedom Muscle Force Driven Fibril-Reinforced Poroviscoelastic Finite Element Model of the Knee Joint

Autori: Esrafilian A., Stenroth L., Mononen M.E., Tanska P., Van Rossom S., Lloyd D.G., Jonkers I., Korhonen R.K.
Pubblicato in: IEEE Transactions on Neural Systems and Rehabilitation Engineering, Numero 29, 2020, Pagina/e 123-133, ISSN 1534-4320
Editore: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tnsre.2020.3037411

Bidirectional cell-matrix interaction dictates neuronal network formation in a brain-mimetic 3D scaffold.

Autori: Samanta S., Ylä-Outinen L., Rangasami V.K., Narkilahti S., Oommen O.P.
Pubblicato in: Acta Biomaterialia, Numero 140, 2021, Pagina/e 314-323, ISSN 1742-7061
Editore: Elsevier BV
DOI: 10.1016/j.actbio.2021.12.010

Fracture behavior of a composite of bone and calcium sulfate/hydroxyapatite.

Autori: Kok J., Törnquist E., Raina D.B., Le Cann S., Novak V., Sirka A., Lidgren L., Grassi L., Isaksson H.
Pubblicato in: Journal of the Mechanical Behavior of Biomedical Materials, Numero 130, 2022, Pagina/e 105201, ISSN 1751-6161
Editore: Elsevier BV
DOI: 10.1016/j.jmbbm.2022.105201

Interpenetrating gallol functionalized tissue adhesive hyaluronic acid hydrogel polarizes macrophages to an immunosuppressive phenotype.

Autori: Samanta S., Rangasami V.K., Sarlus H., Samal J.R.K., Evans A.D., Parihar V.S., Varghese O.P., Harris R.A., Oommen O.P.
Pubblicato in: Acta Biomaterialia, Numero 142, 2022, Pagina/e 36-48, ISSN 1742-7061
Editore: Elsevier BV
DOI: 10.1016/j.actbio.2022.01.048

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