Bridging the gap between supramolecular chemistry and current synthetic challenges: Developing artificial catalysts for the tail-to-head terpene cyclization

Informazioni relative al progetto

TERPENECAT

ID dell’accordo di sovvenzione: 714620

DOI 10.3030/714620

Progetto chiuso

Data della firma CE 30 Ottobre 2016

Data di avvio 1 Novembre 2016

Data di completamento 31 Ottobre 2021

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 500 000,00

Contributo UE € 1 500 000,00

Coordinato da

UNIVERSITAT BASEL
Switzerland

Pubblicazioni

Peer reviewed articles (14)

Sesquiterpene Cyclizations inside the Hexameric Resorcinarene Capsule: Total Synthesis of δ‐Selinene and Mechanistic Studies

Autori: Qi Zhang, Konrad Tiefenbacher
Pubblicato in: Angewandte Chemie International Edition, Numero 58/36, 2019, Pagina/e 12688-12695, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201906753

Concentration-Dependent Self-Assembly of an Unusually Large Hexameric Hydrogen-Bonded Molecular Cage

Autori: Severin Merget, Lorenzo Catti, Shani Zev, Dan T. Major, Nils Trapp, Konrad Tiefenbacher
Pubblicato in: Chemistry - A European Journal, 2021, ISSN 1521-3765
Editore: Wiley-VCH
DOI: 10.1002/chem.202005046

Requirements for Terpene Cyclizations inside the Supramolecular Resorcinarene Capsule: Bound Water and Its Protonation Determine the Catalytic Activity

Autori: Severin Merget, Lorenzo Catti, GiovanniMaria Piccini, Konrad Tiefenbacher
Pubblicato in: Journal of the American Chemical Society, Numero 142/9, 2020, Pagina/e 4400-4410, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.9b13239

Molecular Capsule Catalysis: Ready to Address Current Challenges in Synthetic Organic Chemistry?

Autori: Ivana Némethová, Leonidas-Dimitrios Syntrivanis, Konrad Tiefenbacher
Pubblicato in: CHIMIA International Journal for Chemistry, Numero 74/7, 2020, Pagina/e 561-568, ISSN 0009-4293
Editore: Schweizerische Chemische Gedellschaft
DOI: 10.2533/chimia.2020.561

Four-Step Access to the Sesquiterpene Natural Product Presilphiperfolan-1β-ol and Unnatural Derivatives via Supramolecular Catalysis

Autori: Leonidas-Dimitrios Syntrivanis, Ivana Némethová, Dario Schmid, Shani Levi, Alessandro Prescimone, Fabian Bissegger, Dan T. Major, Konrad Tiefenbacher
Pubblicato in: Journal of the American Chemical Society, Numero 142/12, 2020, Pagina/e 5894-5900, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.0c01464

Brønsted Acid-Catalyzed Carbonyl-Olefin Metathesis inside a Self-Assembled Supramolecular Host

Autori: Lorenzo Catti, Konrad Tiefenbacher
Pubblicato in: Angewandte Chemie International Edition, 2018, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201712141

Chirality Induction from a Chiral Guest to the Hydrogen-Bonding Network of Its Hexameric Resorcinarene Host Capsule

Autori: Corina H. Pollok, Qi Zhang, Konrad Tiefenbacher, Christian Merten
Pubblicato in: ChemPhysChem, Numero 18/15, 2017, Pagina/e 1987-1991, ISSN 1439-4235
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/cphc.201700610

Terpene Cyclizations inside a Supramolecular Catalyst: Leaving-Group-Controlled Product Selectivity and Mechanistic Studies

Autori: Qi Zhang, Lorenzo Catti, Jürgen Pleiss, Konrad Tiefenbacher
Pubblicato in: Journal of the American Chemical Society, Numero 139/33, 2017, Pagina/e 11482-11492, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.7b04480

Elucidating the Importance of Hydrochloric Acid as a Cocatalyst for Resorcinarene-Capsule-Catalyzed Reactions

Autori: Jesper M. Köster, Konrad Tiefenbacher
Pubblicato in: ChemCatChem, 2018, ISSN 1867-3880
Editore: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.201800326

En route to terpene natural products utilizing supramolecular cyclase mimetics

Autori: Qi Zhang, Lorenzo Catti, Leonidas-Dimitrios Syntrivanis, Konrad Tiefenbacher
Pubblicato in: Natural Product Reports, 2019, ISSN 0265-0568
Editore: Royal Society of Chemistry
DOI: 10.1039/c9np00003h

Sesquiterpene cyclizations catalysed inside the resorcinarene capsule and application in the short synthesis of isolongifolene and isolongifolenone

Autori: Qi Zhang, Jan Rinkel, Bernd Goldfuss, Jeroen S. Dickschat, Konrad Tiefenbacher
Pubblicato in: Nature Catalysis, Numero 1/8, 2018, Pagina/e 609-615, ISSN 2520-1158
Editore: Springer Nature Publishing AG
DOI: 10.1038/s41929-018-0115-4

Discovering Monoterpene Catalysis Inside Nanocapsules with Multiscale Modeling and Experiments

Autori: Efrat Pahima, Qi Zhang, Konrad Tiefenbacher, Dan T. Major
Pubblicato in: Journal of the American Chemical Society, Numero 141/15, 2019, Pagina/e 6234-6246, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.8b13411

Catalysis inside the Hexameric Resorcinarene Capsule

Autori: Qi Zhang, Lorenzo Catti, Konrad Tiefenbacher
Pubblicato in: Accounts of Chemical Research, Numero 51/9, 2018, Pagina/e 2107-2114, ISSN 0001-4842
Editore: American Chemical Society
DOI: 10.1021/acs.accounts.8b00320

Optimized iminium-catalysed 1,4-reductions inside the resorcinarene capsule: achieving >90% ee with proline as catalyst

Autori: Daria Sokolova, Konrad Tiefenbacher
Pubblicato in: RSC Advance, 2021, ISSN 2046-2069
Editore: Royal Society of Chemistry
DOI: 10.1039/d1ra04333a