Selective glycoimmuno-targeting for cancer therapy

Pubblicazioni

Association between Neu5Gc carbohydrate and serum antibodies against it provides the molecular link to cancer: French NutriNet-Santé study

Autori: Salam Bashir, Leopold K. Fezeu, Shani Leviatan Ben-Arye, Sharon Yehuda, Eliran Moshe Reuven, Fabien Szabo de Edelenyi, Imen Fellah-Hebia, Thierry Le Tourneau, Berthe Marie Imbert-Marcille, Emmanuel B. Drouet, Mathilde Touvier, Jean-Christian Roussel, Hai Yu, Xi Chen, Serge Hercberg, Emanuele Cozzi, Jean-Paul Soulillou, Pilar Galan, Vered Padler-Karavani
Pubblicato in: BMC Medicine, Numero 18/1, 2020, ISSN 1741-7015
Editore: BioMed Central
DOI: 10.1186/s12916-020-01721-8

The role of antibody responses against glycans in bioprosthetic heart valve calcification and deterioration

Autori: Senage T, Paul A, Le Tourneau T, Fellah-Hebia I, Vadori M, Bashir S, Galiñanes M, Bottio T, Gerosa G, Evangelista A, Badano LP, Nassi A, Costa C, Cesare G, Manji RA, Cueff de Monchy C, Piriou N, Capoulade R, Serfaty JM, Guimbretière G, Dantan E, Ruiz-Majoral A, Coste du Fou G, Leviatan Ben-Arye S, Govani L, Yehuda S, Bachar Abramovitch S, Amon R, Reuven EM, Atiya-Nasagi Y, Yu H, Iop L, Casós K,
Pubblicato in: NATURE MEDICINE, 2022, ISSN 1078-8956
Editore: Nature Publishing Group
DOI: 10.1038/s41591-022-01682-w

Directed Evolution of Therapeutic Antibodies Targeting Glycosylation in Cancer

Autori: Ron Amon, Ronit Rosenfeld, Shahar Perlmutter, Oliver C. Grant, Sharon Yehuda, Aliza Borenstein-Katz, Ron Alcalay, Tal Marshanski, Hai Yu, Ron Diskin, Robert J. Woods, Xi Chen, Vered Padler-Karavani
Pubblicato in: Cancers, Numero 12/10, 2020, Pagina/e 2824, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12102824

Evolution of sialic acids: Implications in xenotransplant biology

Autori: Anu Paul, Vered Padler-Karavani
Pubblicato in: Xenotransplantation, 2018, Pagina/e e12424, ISSN 0908-665X
Editore: Blackwell Publishing Inc.
DOI: 10.1111/xen.12424

ABO Antigens Active Tri- and Disaccharides Microarray to Evaluate C-type Lectin Receptor Binding Preferences

Autori: Chethan D. Shanthamurthy, Prashant Jain, Sharon Yehuda, João T. Monteiro, Shani Leviatan Ben-Arye, Balamurugan Subramani, Bernd Lepenies, Vered Padler-Karavani, Raghavendra Kikkeri
Pubblicato in: Scientific Reports, Numero 8/1, 2018, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-018-24333-y

A combined computational-experimental approach to define the structural origin of antibody recognition of sialyl-Tn, a tumor-associated carbohydrate antigen

Autori: Ron Amon, Oliver C. Grant, Shani Leviatan Ben-Arye, Spandana Makeneni, Anita K. Nivedha, Tal Marshanski, Christoffer Norn, Hai Yu, John N. Glushka, Sarel J. Fleishman, Xi Chen, Robert J. Woods, Vered Padler-Karavani
Pubblicato in: Scientific Reports, Numero 8/1, 2018, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-018-29209-9

Glycan microarray reveal induced IgGs repertoire shift against a dietary carbohydrate in response to rabbit anti-human thymocyte therapy

Autori: Ron Amon, Shani Leviatan Ben-Arye, Limor Engler, Hai Yu, Noha Lim, Ludmilla Le Berre, Kristina M. Harris, Mario R. Ehlers, Stephen E. Gitelman, Xi Chen, Jean-Paul Soulillou, Vered Padler-Karavani
Pubblicato in: Oncotarget, Numero 8/68, 2017, ISSN 1949-2553
Editore: Impact Journals
DOI: 10.18632/oncotarget.23096

Glycan Microarray Reveal the Sweet Side of Cancer Vaccines

Autori: Vered Padler-Karavani
Pubblicato in: Cell Chemical Biology, Numero 23/12, 2016, Pagina/e 1446-1447, ISSN 2451-9456
Editore: Elsevier Ltd.
DOI: 10.1016/j.chembiol.2016.12.002

Nontypeable Haemophilus influenzae Has Evolved Preferential Use of N- Acetylneuraminic Acid as a Host Adaptation

Autori: Preston S. K. Ng, Christopher J. Day, John M. Atack, Lauren E. Hartley-Tassell, Linda E. Winter, Tal Marshanski, Vered Padler-Karavani, Ajit Varki, Stephen J. Barenkamp, Michael A. Apicella, Michael P. Jennings
Pubblicato in: mBio, Numero 10/3, 2019, ISSN 2150-7511
Editore: American Society for Microbiology
DOI: 10.1128/mbio.00422-19

Microarray Analysis of Oligosaccharide-Mediated Multivalent Carbohydrate-Protein Interactions and Their Heterogeneity

Autori: Madhuri Gade, Catherine Alex, Shani Leviatan Ben-Arye, João T. Monteiro, Sharon Yehuda, Bernd Lepenies, Vered Padler-Karavani, Raghavendra Kikkeri
Pubblicato in: ChemBioChem, Numero 19/11, 2018, Pagina/e 1170-1177, ISSN 1439-4227
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.201800037

Biomimetic Glyconanoparticle Vaccine for Cancer Immunotherapy

Autori: Eliran Moshe Reuven, Shani Leviatan Ben-Arye, Hai Yu, Roberto Duchi, Andrea Perota, Sophie Conchon, Shirley Bachar Abramovitch, Jean-Paul Soulillou, Cesare Galli, Xi Chen, Vered Padler-Karavani
Pubblicato in: ACS Nano, Numero 13/3, 2019, Pagina/e 2936-2947, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.8b07241

Presentation Mode of Glycans Affect Recognition of Human Serum anti-Neu5Gc IgG Antibodies

Autori: Salam Bashir, Shani Leviatan Ben Arye, Eliran Moshe Reuven, Hai Yu, Cristina Costa, Manuel Galiñanes, Tomaso Bottio, Xi Chen, Vered Padler-Karavani
Pubblicato in: Bioconjugate Chemistry, Numero 30/1, 2018, Pagina/e 161-168, ISSN 1043-1802
Editore: American Chemical Society
DOI: 10.1021/acs.bioconjchem.8b00817

Differential Recognition of Diet-Derived Neu5Gc-Neoantigens on Glycan Microarrays by Carbohydrate-Specific Pooled Human IgG and IgA Antibodies

Autori: Shani Leviatan Ben-Arye, Christoph Schneider, Hai Yu, Salam Bashir, Xi Chen, Stephan von Gunten, Vered Padler-Karavani
Pubblicato in: Bioconjugate Chemistry, Numero 30/5, 2019, Pagina/e 1565-1574, ISSN 1043-1802
Editore: American Chemical Society
DOI: 10.1021/acs.bioconjchem.9b00273

Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies

Autori: Aliza Borenstein-Katz, Shira Warszawski, Ron Amon, Maayan Eilon, Hadas Cohen-Dvashi, Shani Leviatan Ben-Arye, Nova Tasnima, Hai Yu, Xi Chen, Vered Padler-Karavani, Sarel Jacob Fleishman, Ron Diskin
Pubblicato in: JOURNAL OF MOLECULAR BIOLOGY, 2021, ISSN 0022-2836
Editore: Academic Press
DOI: 10.1016/j.jmb.2021.167099

Editorial: Human Antibodies Against the Dietary Non-human Neu5Gc-Carrying Glycans in Normal and Pathologic States

Autori: Jean-Paul Soulillou, Vered Padler-Karavani
Pubblicato in: Frontiers in Immunology, Numero 11, 2020, ISSN 1664-3224
Editore: FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2020.01589

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