Nose to Brain Delivery of Antibodies via the Olfactory Region for the Treatment of Multiple Sclerosis Using Novel Multi-functional Biomaterials Combined with a Medical Device

Informations projet

N2B-patch

N° de convention de subvention: 721098

DOI

10.3030/721098

Projet clôturé

Date de signature de la CE 9 Novembre 2016

Date de début 1 Janvier 2017

Date de fin 30 Juin 2021

Financé au titre de

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials

Coût total

€ 6 472 998,75

Contribution de l’UE

€ 5 325 498,75

Coordonné par

FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV
Germany

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Websites, patent fillings, videos etc. (1)

Project video

An N2B-patch project video will be prepared in due time and disseminated via several channels (project website, YouTube, events, exhibitions etc.)

Documents, reports (2)

Project logo and project webpage

In order to create a corporate identity for N2B-patch, a project logo will be designed. It will be used for all dissemination and communication purposes. The Project Website will serve as a primary dissemination platform and will be regularly filled with suitable content for Internet publication.

Dissemination material: project flyer and poster

Dissemination material like a project flyer or leaflet and a project poster will be prepared in due time and disseminated via several channels (project website, YouTube, events, exhibi-tions etc.)

Publications

Peer reviewed articles (7)

A Computational Systems Approach to Rational Design of Nose-to-Brain Delivery of Biopharmaceutics

Auteurs: Costas Kiparissides, Athina Vasileiadou, Filippos Karageorgos, Stefania Serpetsi
Publié dans: Industrial & Engineering Chemistry Research, Numéro 59/6, 2020, Page(s) 2548-2565, ISSN 0888-5885
Éditeur: American Chemical Society
DOI: 10.1021/acs.iecr.9b04885

»N2B-Patch« – Nose-To-Brain Delivery of an Active Pharmaceutical Ingredient via the Olfactory Region

Auteurs: Carmen Gruber Traub
Publié dans: Drug Designing & Intellectual Properties International Journal, Numéro 1/4, 2018, ISSN 2637-4706
Éditeur: Lupine Publishers
DOI: 10.32474/ddipij.2018.01.000116

Recent advances in carrier mediated nose-to-brain delivery of pharmaceutics

Auteurs: Bourganis, Vassilis; Kammona, Olga; Alexopoulos, Aleck; Kiparissides, Costas
Publié dans: European Journal of Pharmaceutics and Biopharmaceutics, Numéro 128, 2018, Page(s) 337-362, ISSN 0939-6411
Éditeur: Elsevier BV
DOI: 10.5281/zenodo.1256646

Allogenic Fc Domain-Facilitated Uptake of IgG in Nasal Lamina Propria: Friend or Foe for Intranasal CNS Delivery?

Auteurs: Simone Ladel, Johannes Flamm, Arghavan Soleimani Zadeh, Dorothea Filzwieser, Julia-Christina Walter, Patrick Schlossbauer, Ralf Kinscherf, Katharina Lischka, Harald Luksch, Katharina Schindowski
Publié dans: Pharmaceutics, Numéro 10/3, 2018, Page(s) 107, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics10030107

Tailoring Formulations for Intranasal Nose-to-Brain Delivery: A Review on Architecture, Physico-Chemical Characteristics and Mucociliary Clearance of the Nasal Olfactory Mucosa

Auteurs: Stella Gänger, Katharina Schindowski
Publié dans: Pharmaceutics, Numéro 10/3, 2018, Page(s) 116, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics10030116

Improved In Vitro Model for Intranasal Mucosal Drug Delivery: Primary Olfactory and Respiratory Epithelial Cells Compared with the Permanent Nasal Cell Line RPMI 2650

Auteurs: Simone Ladel, Patrick Schlossbauer, Johannes Flamm, Harald Luksch, Boris Mizaikoff, Katharina Schindowski
Publié dans: Pharmaceutics, Numéro 11/8, 2019, Page(s) 367, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics11080367

A Computational Model for the Analysis of Spreading of Viscoelastic Droplets over Flat Surfaces

Auteurs: Aleck H. Alexopoulos, Costas Kiparissides
Publié dans: Fluids, Numéro 3/4, 2018, Page(s) 78, ISSN 2311-5521
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/fluids3040078