Nose to Brain Delivery of Antibodies via the Olfactory Region for the Treatment of Multiple Sclerosis Using Novel Multi-functional Biomaterials Combined with a Medical Device

Informazioni relative al progetto

N2B-patch

ID dell’accordo di sovvenzione: 721098

DOI

10.3030/721098

Progetto chiuso

Data della firma CE 9 Novembre 2016

Data di avvio 1 Gennaio 2017

Data di completamento 30 Giugno 2021

Finanziato da

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials

Costo totale

€ 6 472 998,75

Contributo UE

€ 5 325 498,75

Coordinato da

FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV
Germany

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Websites, patent fillings, videos etc. (1)

Project video

An N2B-patch project video will be prepared in due time and disseminated via several channels (project website, YouTube, events, exhibitions etc.)

Documents, reports (2)

Project logo and project webpage

In order to create a corporate identity for N2B-patch, a project logo will be designed. It will be used for all dissemination and communication purposes. The Project Website will serve as a primary dissemination platform and will be regularly filled with suitable content for Internet publication.

Dissemination material: project flyer and poster

Dissemination material like a project flyer or leaflet and a project poster will be prepared in due time and disseminated via several channels (project website, YouTube, events, exhibi-tions etc.)

Pubblicazioni

Peer reviewed articles (7)

A Computational Systems Approach to Rational Design of Nose-to-Brain Delivery of Biopharmaceutics

Autori: Costas Kiparissides, Athina Vasileiadou, Filippos Karageorgos, Stefania Serpetsi
Pubblicato in: Industrial & Engineering Chemistry Research, Numero 59/6, 2020, Pagina/e 2548-2565, ISSN 0888-5885
Editore: American Chemical Society
DOI: 10.1021/acs.iecr.9b04885

»N2B-Patch« – Nose-To-Brain Delivery of an Active Pharmaceutical Ingredient via the Olfactory Region

Autori: Carmen Gruber Traub
Pubblicato in: Drug Designing & Intellectual Properties International Journal, Numero 1/4, 2018, ISSN 2637-4706
Editore: Lupine Publishers
DOI: 10.32474/ddipij.2018.01.000116

Recent advances in carrier mediated nose-to-brain delivery of pharmaceutics

Autori: Bourganis, Vassilis; Kammona, Olga; Alexopoulos, Aleck; Kiparissides, Costas
Pubblicato in: European Journal of Pharmaceutics and Biopharmaceutics, Numero 128, 2018, Pagina/e 337-362, ISSN 0939-6411
Editore: Elsevier BV
DOI: 10.5281/zenodo.1256646

Allogenic Fc Domain-Facilitated Uptake of IgG in Nasal Lamina Propria: Friend or Foe for Intranasal CNS Delivery?

Autori: Simone Ladel, Johannes Flamm, Arghavan Soleimani Zadeh, Dorothea Filzwieser, Julia-Christina Walter, Patrick Schlossbauer, Ralf Kinscherf, Katharina Lischka, Harald Luksch, Katharina Schindowski
Pubblicato in: Pharmaceutics, Numero 10/3, 2018, Pagina/e 107, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics10030107

Tailoring Formulations for Intranasal Nose-to-Brain Delivery: A Review on Architecture, Physico-Chemical Characteristics and Mucociliary Clearance of the Nasal Olfactory Mucosa

Autori: Stella Gänger, Katharina Schindowski
Pubblicato in: Pharmaceutics, Numero 10/3, 2018, Pagina/e 116, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics10030116

Improved In Vitro Model for Intranasal Mucosal Drug Delivery: Primary Olfactory and Respiratory Epithelial Cells Compared with the Permanent Nasal Cell Line RPMI 2650

Autori: Simone Ladel, Patrick Schlossbauer, Johannes Flamm, Harald Luksch, Boris Mizaikoff, Katharina Schindowski
Pubblicato in: Pharmaceutics, Numero 11/8, 2019, Pagina/e 367, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics11080367

A Computational Model for the Analysis of Spreading of Viscoelastic Droplets over Flat Surfaces

Autori: Aleck H. Alexopoulos, Costas Kiparissides
Pubblicato in: Fluids, Numero 3/4, 2018, Pagina/e 78, ISSN 2311-5521
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/fluids3040078