Nose to Brain Delivery of Antibodies via the Olfactory Region for the Treatment of Multiple Sclerosis Using Novel Multi-functional Biomaterials Combined with a Medical Device

Información del proyecto

N2B-patch

Identificador del acuerdo de subvención: 721098

DOI

10.3030/721098

Proyecto cerrado

Fecha de la firma de la CE 9 Noviembre 2016

Fecha de inicio 1 Enero 2017

Fecha de finalización 30 Junio 2021

Financiado con arreglo a

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials

Coste total

€ 6 472 998,75

Aportación de la UE

€ 5 325 498,75

Coordinado por

FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV
Germany

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Websites, patent fillings, videos etc. (1)

Project video

An N2B-patch project video will be prepared in due time and disseminated via several channels (project website, YouTube, events, exhibitions etc.)

Documents, reports (2)

Project logo and project webpage

In order to create a corporate identity for N2B-patch, a project logo will be designed. It will be used for all dissemination and communication purposes. The Project Website will serve as a primary dissemination platform and will be regularly filled with suitable content for Internet publication.

Dissemination material: project flyer and poster

Dissemination material like a project flyer or leaflet and a project poster will be prepared in due time and disseminated via several channels (project website, YouTube, events, exhibi-tions etc.)

Publicaciones

Peer reviewed articles (7)

A Computational Systems Approach to Rational Design of Nose-to-Brain Delivery of Biopharmaceutics

Autores: Costas Kiparissides, Athina Vasileiadou, Filippos Karageorgos, Stefania Serpetsi
Publicado en: Industrial & Engineering Chemistry Research, Edición 59/6, 2020, Página(s) 2548-2565, ISSN 0888-5885
Editor: American Chemical Society
DOI: 10.1021/acs.iecr.9b04885

»N2B-Patch« – Nose-To-Brain Delivery of an Active Pharmaceutical Ingredient via the Olfactory Region

Autores: Carmen Gruber Traub
Publicado en: Drug Designing & Intellectual Properties International Journal, Edición 1/4, 2018, ISSN 2637-4706
Editor: Lupine Publishers
DOI: 10.32474/ddipij.2018.01.000116

Recent advances in carrier mediated nose-to-brain delivery of pharmaceutics

Autores: Bourganis, Vassilis; Kammona, Olga; Alexopoulos, Aleck; Kiparissides, Costas
Publicado en: European Journal of Pharmaceutics and Biopharmaceutics, Edición 128, 2018, Página(s) 337-362, ISSN 0939-6411
Editor: Elsevier BV
DOI: 10.5281/zenodo.1256646

Allogenic Fc Domain-Facilitated Uptake of IgG in Nasal Lamina Propria: Friend or Foe for Intranasal CNS Delivery?

Autores: Simone Ladel, Johannes Flamm, Arghavan Soleimani Zadeh, Dorothea Filzwieser, Julia-Christina Walter, Patrick Schlossbauer, Ralf Kinscherf, Katharina Lischka, Harald Luksch, Katharina Schindowski
Publicado en: Pharmaceutics, Edición 10/3, 2018, Página(s) 107, ISSN 1999-4923
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics10030107

Tailoring Formulations for Intranasal Nose-to-Brain Delivery: A Review on Architecture, Physico-Chemical Characteristics and Mucociliary Clearance of the Nasal Olfactory Mucosa

Autores: Stella Gänger, Katharina Schindowski
Publicado en: Pharmaceutics, Edición 10/3, 2018, Página(s) 116, ISSN 1999-4923
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics10030116

Improved In Vitro Model for Intranasal Mucosal Drug Delivery: Primary Olfactory and Respiratory Epithelial Cells Compared with the Permanent Nasal Cell Line RPMI 2650

Autores: Simone Ladel, Patrick Schlossbauer, Johannes Flamm, Harald Luksch, Boris Mizaikoff, Katharina Schindowski
Publicado en: Pharmaceutics, Edición 11/8, 2019, Página(s) 367, ISSN 1999-4923
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics11080367

A Computational Model for the Analysis of Spreading of Viscoelastic Droplets over Flat Surfaces

Autores: Aleck H. Alexopoulos, Costas Kiparissides
Publicado en: Fluids, Edición 3/4, 2018, Página(s) 78, ISSN 2311-5521
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/fluids3040078