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Nose to Brain Delivery of Antibodies via the Olfactory Region for the Treatment of Multiple Sclerosis Using Novel Multi-functional Biomaterials Combined with a Medical Device

Resultado final

Project video

An N2B-patch project video will be prepared in due time and disseminated via several channels (project website, YouTube, events, exhibitions etc.)

Project logo and project webpage

In order to create a corporate identity for N2B-patch, a project logo will be designed. It will be used for all dissemination and communication purposes. The Project Website will serve as a primary dissemination platform and will be regularly filled with suitable content for Internet publication.

Dissemination material: project flyer and poster

Dissemination material like a project flyer or leaflet and a project poster will be prepared in due time and disseminated via several channels (project website, YouTube, events, exhibi-tions etc.)

Publicaciones

A Computational Systems Approach to Rational Design of Nose-to-Brain Delivery of Biopharmaceutics

Autores: Costas Kiparissides, Athina Vasileiadou, Filippos Karageorgos, Stefania Serpetsi
Publicado en: Industrial & Engineering Chemistry Research, 59/6, 2020, Page(s) 2548-2565, ISSN 0888-5885
Editor: American Chemical Society
DOI: 10.1021/acs.iecr.9b04885

»N2B-Patch« – Nose-To-Brain Delivery of an Active Pharmaceutical Ingredient via the Olfactory Region

Autores: Carmen Gruber Traub
Publicado en: Drug Designing & Intellectual Properties International Journal, 1/4, 2018, ISSN 2637-4706
Editor: Lupine Publishers
DOI: 10.32474/ddipij.2018.01.000116

Recent advances in carrier mediated nose-to-brain delivery of pharmaceutics

Autores: Bourganis, Vassilis; Kammona, Olga; Alexopoulos, Aleck; Kiparissides, Costas
Publicado en: European Journal of Pharmaceutics and Biopharmaceutics, 128, 2018, Page(s) 337-362, ISSN 0939-6411
Editor: Elsevier BV
DOI: 10.5281/zenodo.1256646

Allogenic Fc Domain-Facilitated Uptake of IgG in Nasal Lamina Propria: Friend or Foe for Intranasal CNS Delivery?

Autores: Simone Ladel, Johannes Flamm, Arghavan Soleimani Zadeh, Dorothea Filzwieser, Julia-Christina Walter, Patrick Schlossbauer, Ralf Kinscherf, Katharina Lischka, Harald Luksch, Katharina Schindowski
Publicado en: Pharmaceutics, 10/3, 2018, Page(s) 107, ISSN 1999-4923
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics10030107

Tailoring Formulations for Intranasal Nose-to-Brain Delivery: A Review on Architecture, Physico-Chemical Characteristics and Mucociliary Clearance of the Nasal Olfactory Mucosa

Autores: Stella Gänger, Katharina Schindowski
Publicado en: Pharmaceutics, 10/3, 2018, Page(s) 116, ISSN 1999-4923
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics10030116

Improved In Vitro Model for Intranasal Mucosal Drug Delivery: Primary Olfactory and Respiratory Epithelial Cells Compared with the Permanent Nasal Cell Line RPMI 2650

Autores: Simone Ladel, Patrick Schlossbauer, Johannes Flamm, Harald Luksch, Boris Mizaikoff, Katharina Schindowski
Publicado en: Pharmaceutics, 11/8, 2019, Page(s) 367, ISSN 1999-4923
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics11080367

A Computational Model for the Analysis of Spreading of Viscoelastic Droplets over Flat Surfaces

Autores: Aleck H. Alexopoulos, Costas Kiparissides
Publicado en: Fluids, 3/4, 2018, Page(s) 78, ISSN 2311-5521
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/fluids3040078