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CORDIS - Resultados de investigaciones de la UE
CORDIS

Tribbles Research and Innovation Network

Resultado final

8.1

Signing of Consortium Agreement

3.3

Two conference reports on the mechanisms of TRIB-mediated control of AT accrual and function

2.3

Four manuscripts or conference presentations on AT resident immune cells

5.2

Conference abstracts on regulatory ubiquitination and sumoylation of TRIB3 on the control of PI3K/Akt

8.3

ESR advertisements, recruitment

6.3

Manuscript or conference report on the action of TRIB mRNA destabilising miRNAs

4.3

Three manuscripts and/or conference reports on effects of cell-type spec. Trib-/- activity on prostate tumourigenesis

5.5

Manuscript/conference abstract on the TRIB-mediated, cell-specific control of transcription factor turnover

7.3

Press releases

8.7

Final Report

3.4

Two manuscripts focussing on TRIB-dependent changes in VAT and periprostatic AT

6.5

Conference abstract on the functional consequences of E3 inhibition in prostate cancer cells

8.2

Kick-off Meeting

7.2

Consortium Conference

7.1

Setup of website and presence in Social Media

7.4

Coordination of Outreach

Publicaciones

HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis

Autores: Marta Palomo-Irigoyen, Encarni Pérez-Andrés, Marta Iruarrizaga-Lejarreta, Adrián Barreira-Manrique, Miguel Tamayo-Caro, Laura Vila-Vecilla, Leire Moreno-Cugnon, Nagore Beitia, Daniela Medrano, David Fernández-Ramos, Juan José Lozano, Satoshi Okawa, José L. Lavín, Natalia Martín-Martín, James D. Sutherland, Virginia Guitiérez de Juan, Monika Gonzalez-Lopez, Nuria Macías-Cámara, David Mo
Publicado en: Journal of Clinical Investigation, Edición 130/7, 2020, Página(s) 3848-3864, ISSN 0021-9738
Editor: American Society for Clinical Investigation
DOI: 10.1172/jci130379

Integrative analysis of transcriptomics and clinical data uncovers the tumor-suppressive activity of MITF in prostate cancer

Autores: Lorea Valcarcel-Jimenez, Alice Macchia, Natalia Martín-Martín, Ana Rosa Cortazar, Ariane Schaub-Clerigué, Mikel Pujana-Vaquerizo, Sonia Fernández-Ruiz, Isabel Lacasa-Viscasillas, Aida Santos-Martin, Ana Loizaga-Iriarte, Miguel Unda-Urzaiz, Ivana Hermanova, Ianire Astobiza, Mariona Graupera, Julia Starkova, James Sutherland, Rosa Barrio, Ana M. Aransay, Arkaitz Carracedo, Verónica Torrano
Publicado en: Cell Death & Disease, Edición 9/10, 2018, ISSN 2041-4889
Editor: Nature Publishing Group
DOI: 10.1038/s41419-018-1096-6

Cytokine Output of Adipocyte-iNKT Cell Interplay Is Skewed by a Lipid-Rich Microenvironment

Autores: Robert J. van Eijkeren, Imogen Morris, Anouska Borgman, Angela Markovska, Eric Kalkhoven
Publicado en: Frontiers in Endocrinology, Edición 11, 2020, ISSN 1664-2392
Editor: Frontiers in Endochrinology
DOI: 10.3389/fendo.2020.00479

Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium

Autores: Ingrid Gomez, Ben Ward, Celine Souilhol, Chiara Recarti, Mark Ariaans, Jessica Johnston, Amanda Burnett, Marwa Mahmoud, Le Anh Luong, Laura West, Merete Long, Sion Parry, Rachel Woods, Carl Hulston, Birke Benedikter, Chiara Niespolo, Rohit Bazaz, Sheila Francis, Endre Kiss-Toth, Marc van Zandvoort, Andreas Schober, Paul Hellewell, Paul C. Evans, Victoria Ridger
Publicado en: Nature Communications, Edición 11/1, 2020, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-019-14043-y

Tribbles-1 expression and its function to control inflammatory cytokines, including Interleukin-8 levels are regulated by miRNAs in macrophages and prostate cancer cells

Autores: Chiara Niespolo, Jessica M Johnston, Sumeet R Deshmukh, Swapna Satam, Ziyanda Shologu, TRAIN Consortium, Oscar Villacanas, Ian M Subery, Heather L Wilson, Endre Kiss-Toth
Publicado en: Frontiers in Immunology, 2020, ISSN 1663-4365
Editor: Frontiers Research Foundation
DOI: 10.3389/fimmu.2020.574046

Long Non-Coding RNAs in Metabolic Organs and Energy Homeostasis

Autores: Maude Giroud, Marcel Scheideler
Publicado en: International Journal of Molecular Sciences, Edición 18/12, 2017, Página(s) 2578, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms18122578

Genomic and Functional Regulation of TRIB1 Contributes to Prostate Cancer Pathogenesis

Autores: Parastoo Shahrouzi, Ianire Astobiza, Ana R. Cortazar, Verónica Torrano, Alice Macchia, Juana M. Flores, Chiara Niespolo, Isabel Mendizabal, Ruben Caloto, Amaia Ercilla, Laura Camacho, Leire Arreal, Maider Bizkarguenaga, Maria L. Martinez-Chantar, Xose R. Bustelo, Edurne Berra, Endre Kiss-Toth, Guillermo Velasco, Amaia Zabala-Letona, Arkaitz Carracedo
Publicado en: Cancers, Edición 12/9, 2020, Página(s) 2593, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12092593

Mylk3 null C57BL/6N mice develop cardiomyopathy, whereas Nnt null C57BL/6J mice do not

Autores: Jack L Williams, Anju Paudyal, Sherine Awad, James Nicholson, Dominika Grzesik, Joaquin Botta, Eirini Meimaridou, Avinaash V Maharaj, Michelle Stewart, Andrew Tinker, Roger D Cox, Lou A Metherell
Publicado en: Life Science Alliance, Edición 3/4, 2020, Página(s) e201900593, ISSN 2575-1077
Editor: Life Science Alliance LLC
DOI: 10.26508/lsa.201900593

Multiplex SERS Detection of Metabolic Alterations in Tumor Extracellular Media

Autores: Javier Plou, Isabel García, Mathias Charconnet, Ianire Astobiza, Clara García‐Astrain, Cristiano Matricardi, Agustín Mihi, Arkaitz Carracedo, Luis M. Liz‐Marzán
Publicado en: Advanced Functional Materials, Edición 30/17, 2020, Página(s) 1910335, ISSN 1616-301X
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.201910335

Atheroprone flow activates inflammation via endothelial ATP-dependent P2X7-p38 signalling

Autores: Jack P Green, Celine Souilhol, Ioannis Xanthis, Laura Martinez-Campesino, Neil P Bowden, Paul C Evans, Heather L Wilson
Publicado en: Cardiovascular Research, Edición 114/2, 2017, Página(s) 324-335, ISSN 0008-6363
Editor: Elsevier BV
DOI: 10.1093/cvr/cvx213

Experimental models of murine atherosclerosis: does perception match reality?

Autores: Jessica M Johnston, Sheila E Francis, Endre Kiss-Toth
Publicado en: Cardiovascular Research, 2018, ISSN 0008-6363
Editor: Elsevier BV
DOI: 10.1093/cvr/cvy140

FXR Isoforms Control Different Metabolic Functions in Liver Cells via Binding to Specific DNA Motifs

Autores: Jose Miguel Ramos Pittol, Alexandra Milona, Imogen Morris, Ellen C.L. Willemsen, Suzanne W. van der Veen, Eric Kalkhoven, Saskia W.C. van Mil
Publicado en: Gastroenterology, Edición 159/5, 2020, Página(s) 1853-1865.e10, ISSN 0016-5085
Editor: W. B. Saunders Co., Ltd.
DOI: 10.1053/j.gastro.2020.07.036

Highlights of the 2nd International Symposium on Tribbles and Diseases: tribbles tremble in therapeutics for immunity, metabolism, fundamental cell biology and cancer

Autores: Cui, Bing Eyers, Patrick A. Dobens, Leonard L. Tan, Nguan Soon Mace, Peter D. Link, Wolfgang A. Kiss-Toth, Endre Keeshan, Karen Nakamura, Takuro Pear, Warren S. Feseha, Yodit Johnston, Jessica Carracedo, Arkatiz Scheideler, Marcel llyas, Zabra Bauer, Robert C. Erusalimsky, Jorge
Publicado en: Acta Pharmaceutica Sinica B, Edición 9/2, 2019, Página(s) 443-454, ISSN 2211-3835
Editor: Elsevier BV
DOI: 10.1016/j.apsb.2018.12.007

Post-transcriptional regulation of trib1 by mirnas in primary macrophages

Autores: Chiara Niespolo, Juan Salamanca Viloria, Oscar Villacanas Perez, Heather Wilson, Endre Kiss-Toth
Publicado en: Heart, Edición Volume 104, Edición Supp 6, 2018
Editor: BMJ Journals
DOI: 10.1136/heartjnl-2018-BCS.109

TRIB3-mediated regulationof macrophage phenotype

Autores: Laura Martinez Campesino, Jessica Johnston, Endre Kiss-Toth, Heather Wilson
Publicado en: Heart, Edición Vol 104, Edición Suppl 6, 2018
Editor: BMJ Publishing Group Limited
DOI: 10.1136/heartjnl-2018-BCS.113

FaDA: A Shiny web application to accelerate common lab data analyses

Autores: Yodit Feseha; Quentin Moiteaux; Estelle Geffard; Gérard Ramstein; Sophie Brouard; Richard Danger
Publicado en: BioRxiv, Edición 5, 2020
Editor: Cold Spring Harbour Laboratory
DOI: 10.1101/2020.04.23.055673

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