Tribbles Research and Innovation Network

Informacje na temat projektu

TRAIN

Identyfikator umowy o grant: 721532

DOI

10.3030/721532

Projekt został zamknięty

Data podpisania przez KE 29 Sierpnia 2016

Data rozpoczęcia 1 Września 2016

Data zakończenia 30 Listopada 2020

Finansowanie w ramach

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Koszt całkowity

€ 3 818 969,68

Wkład UE

€ 3 818 969,68

Koordynowany przez

THE UNIVERSITY OF SHEFFIELD
United Kingdom

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (12)

8.1

Signing of Consortium Agreement

3.3

Two conference reports on the mechanisms of TRIB-mediated control of AT accrual and function

2.3

Four manuscripts or conference presentations on AT resident immune cells

5.2

Conference abstracts on regulatory ubiquitination and sumoylation of TRIB3 on the control of PI3K/Akt

8.3

ESR advertisements, recruitment

6.3

Manuscript or conference report on the action of TRIB mRNA destabilising miRNAs

4.3

Three manuscripts and/or conference reports on effects of cell-type spec. Trib-/- activity on prostate tumourigenesis

5.5

Manuscript/conference abstract on the TRIB-mediated, cell-specific control of transcription factor turnover

7.3

Press releases

8.7

Final Report

3.4

Two manuscripts focussing on TRIB-dependent changes in VAT and periprostatic AT

6.5

Conference abstract on the functional consequences of E3 inhibition in prostate cancer cells

Websites, patent fillings, videos etc. (3)

8.2

Kick-off Meeting

7.2

Consortium Conference

7.1

Setup of website and presence in Social Media

Other (1)

7.4

Coordination of Outreach

Publikacje

Peer reviewed articles (12)

HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis

Autorzy: Marta Palomo-Irigoyen, Encarni Pérez-Andrés, Marta Iruarrizaga-Lejarreta, Adrián Barreira-Manrique, Miguel Tamayo-Caro, Laura Vila-Vecilla, Leire Moreno-Cugnon, Nagore Beitia, Daniela Medrano, David Fernández-Ramos, Juan José Lozano, Satoshi Okawa, José L. Lavín, Natalia Martín-Martín, James D. Sutherland, Virginia Guitiérez de Juan, Monika Gonzalez-Lopez, Nuria Macías-Cámara, David Mo
Opublikowane w: Journal of Clinical Investigation, Numer 130/7, 2020, Strona(/y) 3848-3864, ISSN 0021-9738
Wydawca: American Society for Clinical Investigation
DOI: 10.1172/jci130379

Integrative analysis of transcriptomics and clinical data uncovers the tumor-suppressive activity of MITF in prostate cancer

Autorzy: Lorea Valcarcel-Jimenez, Alice Macchia, Natalia Martín-Martín, Ana Rosa Cortazar, Ariane Schaub-Clerigué, Mikel Pujana-Vaquerizo, Sonia Fernández-Ruiz, Isabel Lacasa-Viscasillas, Aida Santos-Martin, Ana Loizaga-Iriarte, Miguel Unda-Urzaiz, Ivana Hermanova, Ianire Astobiza, Mariona Graupera, Julia Starkova, James Sutherland, Rosa Barrio, Ana M. Aransay, Arkaitz Carracedo, Verónica Torrano
Opublikowane w: Cell Death & Disease, Numer 9/10, 2018, ISSN 2041-4889
Wydawca: Nature Publishing Group
DOI: 10.1038/s41419-018-1096-6

Cytokine Output of Adipocyte-iNKT Cell Interplay Is Skewed by a Lipid-Rich Microenvironment

Autorzy: Robert J. van Eijkeren, Imogen Morris, Anouska Borgman, Angela Markovska, Eric Kalkhoven
Opublikowane w: Frontiers in Endocrinology, Numer 11, 2020, ISSN 1664-2392
Wydawca: Frontiers in Endochrinology
DOI: 10.3389/fendo.2020.00479

Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium

Autorzy: Ingrid Gomez, Ben Ward, Celine Souilhol, Chiara Recarti, Mark Ariaans, Jessica Johnston, Amanda Burnett, Marwa Mahmoud, Le Anh Luong, Laura West, Merete Long, Sion Parry, Rachel Woods, Carl Hulston, Birke Benedikter, Chiara Niespolo, Rohit Bazaz, Sheila Francis, Endre Kiss-Toth, Marc van Zandvoort, Andreas Schober, Paul Hellewell, Paul C. Evans, Victoria Ridger
Opublikowane w: Nature Communications, Numer 11/1, 2020, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-019-14043-y

Tribbles-1 expression and its function to control inflammatory cytokines, including Interleukin-8 levels are regulated by miRNAs in macrophages and prostate cancer cells

Autorzy: Chiara Niespolo, Jessica M Johnston, Sumeet R Deshmukh, Swapna Satam, Ziyanda Shologu, TRAIN Consortium, Oscar Villacanas, Ian M Subery, Heather L Wilson, Endre Kiss-Toth
Opublikowane w: Frontiers in Immunology, 2020, ISSN 1663-4365
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fimmu.2020.574046

Long Non-Coding RNAs in Metabolic Organs and Energy Homeostasis

Autorzy: Maude Giroud, Marcel Scheideler
Opublikowane w: International Journal of Molecular Sciences, Numer 18/12, 2017, Strona(/y) 2578, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms18122578

Genomic and Functional Regulation of TRIB1 Contributes to Prostate Cancer Pathogenesis

Autorzy: Parastoo Shahrouzi, Ianire Astobiza, Ana R. Cortazar, Verónica Torrano, Alice Macchia, Juana M. Flores, Chiara Niespolo, Isabel Mendizabal, Ruben Caloto, Amaia Ercilla, Laura Camacho, Leire Arreal, Maider Bizkarguenaga, Maria L. Martinez-Chantar, Xose R. Bustelo, Edurne Berra, Endre Kiss-Toth, Guillermo Velasco, Amaia Zabala-Letona, Arkaitz Carracedo
Opublikowane w: Cancers, Numer 12/9, 2020, Strona(/y) 2593, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12092593

Mylk3 null C57BL/6N mice develop cardiomyopathy, whereas Nnt null C57BL/6J mice do not

Autorzy: Jack L Williams, Anju Paudyal, Sherine Awad, James Nicholson, Dominika Grzesik, Joaquin Botta, Eirini Meimaridou, Avinaash V Maharaj, Michelle Stewart, Andrew Tinker, Roger D Cox, Lou A Metherell
Opublikowane w: Life Science Alliance, Numer 3/4, 2020, Strona(/y) e201900593, ISSN 2575-1077
Wydawca: Life Science Alliance LLC
DOI: 10.26508/lsa.201900593

Multiplex SERS Detection of Metabolic Alterations in Tumor Extracellular Media

Autorzy: Javier Plou, Isabel García, Mathias Charconnet, Ianire Astobiza, Clara García‐Astrain, Cristiano Matricardi, Agustín Mihi, Arkaitz Carracedo, Luis M. Liz‐Marzán
Opublikowane w: Advanced Functional Materials, Numer 30/17, 2020, Strona(/y) 1910335, ISSN 1616-301X
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.201910335

Atheroprone flow activates inflammation via endothelial ATP-dependent P2X7-p38 signalling

Autorzy: Jack P Green, Celine Souilhol, Ioannis Xanthis, Laura Martinez-Campesino, Neil P Bowden, Paul C Evans, Heather L Wilson
Opublikowane w: Cardiovascular Research, Numer 114/2, 2017, Strona(/y) 324-335, ISSN 0008-6363
Wydawca: Elsevier BV
DOI: 10.1093/cvr/cvx213

Experimental models of murine atherosclerosis: does perception match reality?

Autorzy: Jessica M Johnston, Sheila E Francis, Endre Kiss-Toth
Opublikowane w: Cardiovascular Research, 2018, ISSN 0008-6363
Wydawca: Elsevier BV
DOI: 10.1093/cvr/cvy140

FXR Isoforms Control Different Metabolic Functions in Liver Cells via Binding to Specific DNA Motifs

Autorzy: Jose Miguel Ramos Pittol, Alexandra Milona, Imogen Morris, Ellen C.L. Willemsen, Suzanne W. van der Veen, Eric Kalkhoven, Saskia W.C. van Mil
Opublikowane w: Gastroenterology, Numer 159/5, 2020, Strona(/y) 1853-1865.e10, ISSN 0016-5085
Wydawca: W. B. Saunders Co., Ltd.
DOI: 10.1053/j.gastro.2020.07.036

Non-peer reviewed articles (1)

Highlights of the 2nd International Symposium on Tribbles and Diseases: tribbles tremble in therapeutics for immunity, metabolism, fundamental cell biology and cancer

Autorzy: Cui, Bing Eyers, Patrick A. Dobens, Leonard L. Tan, Nguan Soon Mace, Peter D. Link, Wolfgang A. Kiss-Toth, Endre Keeshan, Karen Nakamura, Takuro Pear, Warren S. Feseha, Yodit Johnston, Jessica Carracedo, Arkatiz Scheideler, Marcel llyas, Zabra Bauer, Robert C. Erusalimsky, Jorge
Opublikowane w: Acta Pharmaceutica Sinica B, Numer 9/2, 2019, Strona(/y) 443-454, ISSN 2211-3835
Wydawca: Elsevier BV
DOI: 10.1016/j.apsb.2018.12.007

Conference proceedings (2)

Post-transcriptional regulation of trib1 by mirnas in primary macrophages

Autorzy: Chiara Niespolo, Juan Salamanca Viloria, Oscar Villacanas Perez, Heather Wilson, Endre Kiss-Toth
Opublikowane w: Heart, Numer Volume 104, Numer Supp 6, 2018
Wydawca: BMJ Journals
DOI: 10.1136/heartjnl-2018-BCS.109

TRIB3-mediated regulationof macrophage phenotype

Autorzy: Laura Martinez Campesino, Jessica Johnston, Endre Kiss-Toth, Heather Wilson
Opublikowane w: Heart, Numer Vol 104, Numer Suppl 6, 2018
Wydawca: BMJ Publishing Group Limited
DOI: 10.1136/heartjnl-2018-BCS.113

Other (1)

FaDA: A Shiny web application to accelerate common lab data analyses

Autorzy: Yodit Feseha; Quentin Moiteaux; Estelle Geffard; Gérard Ramstein; Sophie Brouard; Richard Danger
Opublikowane w: BioRxiv, Numer 5, 2020
Wydawca: Cold Spring Harbour Laboratory
DOI: 10.1101/2020.04.23.055673