CORDIS - Resultados de investigaciones de la UE
CORDIS

Training European Experts in Multilevel Bioimaging, Analysis and Modelling of Vertebrate Development and Disease

Descripción del proyecto

Formación en el ámbito de la imagenología de procesos biológicos

Los avances en las tecnologías de imagenología posibilitan visualizar procesos biológicos en modelos animales a nivel celular o subcelular. Para investigar enfermedades y allanar el camino al diseño de nuevos tratamientos, estas novedosas capacidades de imagenología deben ajustarse a las muestras biológicas empleadas habitualmente en los laboratorios de investigación. En el proyecto ImageInLife, financiado por las acciones Marie Skłodowska-Curie, se formará a la nueva generación de científicos en la obtención de imágenes de sistemas biológicos complejos. Se abordarán los cuellos de botella científicos y los retos relacionados con la optimización de la preparación de muestras, el desarrollo de instrumentos y el análisis de imágenes. Los investigadores también se centrarán en el diseño de nuevos programas informáticos para el análisis y modelización de imágenes médicas.

Objetivo

This proposal sprang from European scientists in both academia and industry who identified a common challenge: setting up a training frame to educate the next generation of imagers in complex biological systems (healthy & pathological), so they are able to master all major aspects of this competitive field and bring important innovations to universities and companies.
The long-term goal of any initiative to image biological processes is reaching cellular or subcellular resolution in a complete organism. This is now possible using vertebrate embryos as models and the most recent technological advances as tools. ESRs will be trained by addressing the following scientific bottlenecks and challenges:
-Preparing vertebrate embryos (rodent & zebrafish) for optimal imaging
-Fine-tuning sensors, reporters and actuators to track cell types, cellular processes and behaviours in living organisms
-Developing and implementing new imaging instruments
-Analysing complex sets of big-data images to extract relevant information
-Using processed images to design computational and mathematical models of development and pathologies
-Comparing these models with experimental data and create a feedback loop improving the whole work chain from sample preparation to instrumentation and analysis.
This interdisciplinary training is based on an intersectoral organisation of the consortium with partners from academia and companies that need these future experts to develop new instruments, screen drugs and chemicals in living systems and develop software to analyse and model medical images. The full training programme is based on an optimal balance between training through research and many network-wide training events, including conferences with physical presence, digital conferences and monthly videolink events.
Consortium members are keen to implement both classical and original outreach activities (eg MOOCs, serious games, Lego designs) to bring state-of-the-art microscopy to the classroom.

Coordinador

UNIVERSITE DE MONTPELLIER
Aportación neta de la UEn
€ 262 875,60
Dirección
163 RUE AUGUSTE BROUSSONNET
34090 Montpellier
Francia

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Región
Occitanie Languedoc-Roussillon Hérault
Tipo de actividad
Higher or Secondary Education Establishments
Enlaces
Coste total
€ 262 875,60

Participantes (11)

Socios (6)