CORDIS - Résultats de la recherche de l’UE
CORDIS

Training European Experts in Multilevel Bioimaging, Analysis and Modelling of Vertebrate Development and Disease

Description du projet

Formation à l’imagerie des processus biologiques

Les progrès des technologies d’imagerie permettent désormais de visualiser, au niveau cellulaire ou subcellulaire, les processus biologiques de modèles animaux. Pour étudier les conditions pathologiques et ouvrir la voie à la conception de nouvelles thérapies, ces nouvelles capacités d’imagerie doivent être adaptées aux spécimens biologiques habituellement utilisés dans les laboratoires de recherche. Financé par le programme Actions Marie Skłodowska-Curie, le projet ImageInLife formera la nouvelle génération de scientifiques à l’imagerie des systèmes biologiques complexes. Le projet abordera les divers goulets d’étranglement scientifiques et défis liés à l’optimisation de la préparation des échantillons, au développement d’instruments et à l’analyse d’images. Les chercheurs se concentreront également sur la conception de nouveaux logiciels destinés à l’analyse et la modélisation d’images médicales.

Objectif

This proposal sprang from European scientists in both academia and industry who identified a common challenge: setting up a training frame to educate the next generation of imagers in complex biological systems (healthy & pathological), so they are able to master all major aspects of this competitive field and bring important innovations to universities and companies.
The long-term goal of any initiative to image biological processes is reaching cellular or subcellular resolution in a complete organism. This is now possible using vertebrate embryos as models and the most recent technological advances as tools. ESRs will be trained by addressing the following scientific bottlenecks and challenges:
-Preparing vertebrate embryos (rodent & zebrafish) for optimal imaging
-Fine-tuning sensors, reporters and actuators to track cell types, cellular processes and behaviours in living organisms
-Developing and implementing new imaging instruments
-Analysing complex sets of big-data images to extract relevant information
-Using processed images to design computational and mathematical models of development and pathologies
-Comparing these models with experimental data and create a feedback loop improving the whole work chain from sample preparation to instrumentation and analysis.
This interdisciplinary training is based on an intersectoral organisation of the consortium with partners from academia and companies that need these future experts to develop new instruments, screen drugs and chemicals in living systems and develop software to analyse and model medical images. The full training programme is based on an optimal balance between training through research and many network-wide training events, including conferences with physical presence, digital conferences and monthly videolink events.
Consortium members are keen to implement both classical and original outreach activities (eg MOOCs, serious games, Lego designs) to bring state-of-the-art microscopy to the classroom.

Coordinateur

UNIVERSITE DE MONTPELLIER
Contribution nette de l'UE
€ 262 875,60
Adresse
163 RUE AUGUSTE BROUSSONNET
34090 Montpellier
France

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Région
Occitanie Languedoc-Roussillon Hérault
Type d’activité
Higher or Secondary Education Establishments
Liens
Coût total
€ 262 875,60

Participants (11)

Partenaires (6)