Translational Research Network in Prostate Cancer

Risultati finali

Recruitment of ESRs

Abstracts for international conferences; Publications submitted to high impact journals
Theses and awarding of doctoral degrees

These and awarding of doctoral degrees

PCDP and researcher declarations

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Pubblicazioni

A meta-analytical approach to the molecular subtyping of prostate cancer

Autori: McKinney C
Pubblicato in: European Urology Supplements, Numero 18/08, 2019, Pagina/e e3126, ISSN 1569-9056
Editore: Elsevier B.V.

Proteomic analysis of formalin fixed tissues for the investigation of prostate cancer

Autori: Mantsiou A, Makridakis M, Fasoulakis K, Fasoulakis C, Zoidakis J, Vlahou A
Pubblicato in: European Urology Supplements, Numero 18/08, 2019, Pagina/e e3081, ISSN 1569-9056
Editore: Elsevier B.V.

In vitro prostate differentiation of induced pluripotent stem cells and organoid generation using seminal vesicle mesenchyme

Autori: Singh P, Robson C.N, Heer R
Pubblicato in: European Urology Supplements, Numero 17/10, 2018, Pagina/e e2557, ISSN 1569-9056
Editore: Elsevier B.V.

In vitro prostate tissue generation using induced pluripotent stem cells and rodent seminal vesicle mesenchyme

Autori: Singh P, Robson C.N, Heer R
Pubblicato in: European Urology Supplements, Numero 18/08, 2019, Pagina/e e3092, ISSN 1569-9056
Editore: Elsevier B.V.

Approaches to enrich for androgen receptor binding sites in low-cell number samples

Autori: Umbreen S, Steele R.E., Poulose N, Mcdade S, Mccabe N, Mills I.G.
Pubblicato in: European Urology Supplements, Numero 17/10, 2018, Pagina/e e2499, ISSN 1569-9056
Editore: Elsevier B.V.

SLFN5 regulates amino acid metabolism by altering LAT1 expression in CRPC

Autori: Sánchez Martínez R, Salji M, Rushworth L, Galbraith L, Knight J, Samson O, Rodriguez Blanco G, Mackay G, Lilla S, Zanivan S, Blomme A, Leung H
Pubblicato in: European Urology Supplements, Numero 18/08, 2019, Pagina/e e3068, ISSN 1569-9056
Editore: Elsevier B.V.

Establishment of prostate cancer organoids: tips, tricks and pitfalls

Autori: Van Hemelryk A, Teubel W.J., De Ridder C.M.A., Erkens-Schulze S, Mout L, Van Royen M.E, Van Weerden W.M.
Pubblicato in: European Urology Supplements, Numero 17/10, 2018, Pagina/e e2530, ISSN 1569-9056
Editore: Elsevier B.V.

Evaluating multicellular contributions to the maintenance of AR activity under conditions of androgen deprivation

Autori: Umbreen S, Steele R.E., Poulose N, Congiano M, Afshan S, Beumer I, Nees M, Harkonen P, Mccabe N, Mcdade S, Mills I.G.
Pubblicato in: European Urology Supplements, Numero 18/08, 2019, Pagina/e e3137, ISSN 1569-9056
Editore: Elsevier B.V.

Characterization of robust and prognostic molecular subtypes in prostate cancer

Autori: McKinney C, McCabe N, Harkin D.P., Kennedy R, Blayney J
Pubblicato in: Cancer Research, 2020
Editore: American Association for Cancer Research
DOI: 10.1158/1538-7445.am2020-2135

Assessment of prostate cancer aggressiveness using metabolomics evaluation of urine by NMR spectroscopy

Autori: Kdadra M, Jagdhuber R, Kremer W, Eiglsperger J, Schiffer E
Pubblicato in: European Urology Supplements, Numero 18/08, 2019, Pagina/e e3111, ISSN 1569-9056
Editore: Elsevier B.V.

A meta-analytical approach to the molecular subtyping of prostate cancer

Autori: Mckinney C, Mccabe N, Harkin D.P, Kennedy R, Blayney J
Pubblicato in: European Urology Supplements, Numero 17/10, 2018, Pagina/e e2510, ISSN 1569-9056
Editore: Elsevier B.V.

A novel panel of patient-derived preclinical models of prostate cancer: xenografts and PDX-derived organoids to recapitulate patients disease profiles

Autori: Van Hemelryk A, De Ridder C.M.A., Erkens-Schulze S, Teubel W.J., Stuurman D, Mc Kinney C, Cangiano M, Beumer I.J., Van WeerdenW.M.
Pubblicato in: European Urology Supplements, Numero 18/08, 2019, Pagina/e e3116, ISSN 1569-9056
Editore: Elsevier B.V.

Study on the possible interactions between FGFRL1- and AR-regulated mechanisms in prostate cancer

Autori: Afshan S, Umbreen S, Yu L, Toriseva M, Nees M, Härkönen P, Mills I
Pubblicato in: European Urology Supplements, Numero 18/08, 2019, Pagina/e e3039, ISSN 1569-9056
Editore: Elsevier B.V.

Identification of novel long non-coding RNA based biomarkers in prostate cancer

Autori: Sattari M, Kohvakka A, Urhonen H, Moradi E, Rauhala H, Nykter M, Latonen L, Bova G.S., Kesseli J, Visakorpi T
Pubblicato in: European Urology Supplements, Numero 18/08, 2019, Pagina/e e3078, ISSN 1569-9056
Editore: Elsevier B.V.

Regulation of SLFN5 by androgens in castration resistant prostate cancer

Autori: Sánchez Martínez R, Salji M , Rushworth L, Lilla S, Zanivan S, Leung H
Pubblicato in: European Urology Supplements, Numero 17/10, 2018, Pagina/e e2555, ISSN 1569-9056
Editore: Elsevier B.V.

Proteomic studies in clinical tissues for the investigation of prostate cancer

Autori: Mantsiou A, Zoidakis J, Vlahou A
Pubblicato in: European Urology Supplements, Numero 17/10, 2018, Pagina/e e2498, ISSN 1569-9056
Editore: Elsevier B.V.

Network analysis of prostate cancer-derived CWR22, LNCaP and VCAP xenografts for elucidation of the key regulators in castration resistance development

Autori: Cangiano M, Granchi Z, Janssen B, Salji M, Leung H
Pubblicato in: European Urology Supplements, Numero 17/10, 2018, Pagina/e e2483, ISSN 1569-9056
Editore: Elsevier B.V.

A transcription factor activity profile as a prognostic signature for recurrence predisposition in prostate cancer patients.

Autori: Cangiano M, Leung H, Janssen B, Nykter M, Jenster G
Pubblicato in: European Urology Supplements, Numero 18/08, 2019, Pagina/e e3048-e3049, ISSN 1569-9056
Editore: Elsevier B.V.

Gene Regulation Network Analysis on Human Prostate Orthografts Highlights a Potential Role for the JMJD6 Regulon in Clinical Prostate Cancer

Autori: Mario Cangiano, Magda Grudniewska, Mark J. Salji, Matti Nykter, Guido Jenster, Alfonso Urbanucci, Zoraide Granchi, Bart Janssen, Graham Hamilton, Hing Y. Leung, Inès J. Beumer
Pubblicato in: Cancers, Numero 13/9, 2021, Pagina/e 2094, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13092094

Proteomics Analysis of Formalin Fixed Paraffin Embedded Tissues in the Investigation of Prostate Cancer

Autori: Anna Mantsiou, Manousos Makridakis, Konstantinos Fasoulakis, Ioannis Katafigiotis, Constantinos A. Constantinides, Jerome Zoidakis, Maria G. Roubelakis, Antonia Vlahou, Vasiliki Lygirou
Pubblicato in: Journal of Proteome Research, Numero 19/7, 2020, Pagina/e 2631-2642, ISSN 1535-3893
Editore: American Chemical Society
DOI: 10.1021/acs.jproteome.9b00587

The induction of core pluripotency master regulators in cancers defines poor clinical outcomes and treatment resistance

Autori: A. C. Hepburn, R. E. Steele, R. Veeratterapillay, L. Wilson, E. E. Kounatidou, A. Barnard, P. Berry, J. R. Cassidy, M. Moad, A. El-Sherif, L. Gaughan, I. G. Mills, C. N. Robson, R. Heer
Pubblicato in: Oncogene, Numero 38/22, 2019, Pagina/e 4412-4424, ISSN 0950-9232
Editore: Nature Publishing Group
DOI: 10.1038/s41388-019-0712-y

Novel patient-derived 3D culture models to guide clinical decision-making in prostate cancer

Autori: Annelies Van Hemelryk, Wytske M. van Weerden
Pubblicato in: Current Opinion in Endocrine and Metabolic Research, Numero 10, 2020, Pagina/e 7-15, ISSN 2451-9650
Editore: Elsevier Ltd.
DOI: 10.1016/j.coemr.2020.02.005

Propagation of human prostate tissue from induced pluripotent stem cells

Autori: Anastasia C. Hepburn, Emma L. Curry, Mohammad Moad, Rebecca E. Steele, Omar E. Franco, Laura Wilson, Parmveer Singh, Adriana Buskin, Susan E. Crawford, Luke Gaughan, Ian G. Mills, Simon W. Hayward, Craig N. Robson, Rakesh Heer
Pubblicato in: STEM CELLS Translational Medicine, Numero 9/7, 2020, Pagina/e 734-745, ISSN 2157-6564
Editore: AlphaMed Press
DOI: 10.1002/sctm.19-0286

Metabolomics Biomarkers of Prostate Cancer: A Systematic Review

Autori: Marouane Kdadra, Sebastian Höckner, Hing Leung, Werner Kremer, Eric Schiffer
Pubblicato in: Diagnostics, Numero 9/1, 2019, Pagina/e 21, ISSN 2075-4418
Editore: Multidisciplinary Digital Publishing Institute
DOI: 10.3390/diagnostics9010021

Tissue proteomics studies in the investigation of prostate cancer

Autori: Anna Mantsiou, Antonia Vlahou, Jerome Zoidakis
Pubblicato in: Expert Review of Proteomics, Numero 15/7, 2018, Pagina/e 593-611, ISSN 1478-9450
Editore: Future Drugs Ltd.
DOI: 10.1080/14789450.2018.1491796

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