Description du projet
Percer les mystères du vieillissement
Le vieillissement est un facteur de risque important associé à nombreuses maladies. Il est donc indispensable de mieux comprendre ses mécanismes biologiques. Le projet IMforFUTURE, financé par l’UE, mènera un programme de formation à la recherche pluridisciplinaire et intersectorielle destiné à dépasser les limites actuelles de la recherche en sciences omiques et d’approfondir les connaissances concernant le vieillissement et les maladies qui y sont liées. Plus précisément, il intégrera des ensembles de données génétiques, glycomiques et épigénomiques à la biologie des systèmes. Par le biais de nouvelles méthodes d’analyse des données et d’analyse omique à haut débit, IMforFUTURE entend appréhender les processus biologiques complexes qui sous-tendent le vieillissement et les maladies. Ce projet, qui rassemble sept partenaires universitaires et quatre partenaires industriels, fournira aux chercheurs en début de carrière les compétences essentielles requises pour concilier diverses disciplines et révolutionner le domaine de la recherche en sciences omiques.
Objectif
IMforFUTURE is an innovative multidisciplinary and intersectoral research training programme which addresses current shortcomings in omics research. We aim to open the new research horizon in integration of genetics, glycomics, and epigenomics datasets into systems biology by developing innovative methods for high throughput omics and for integrative analysis of omics data. We focus on ageing, which is the biggest single risk factor for many diseases. By application of our novel methods to emerging datasets representing inflammation and immunology, IMforFUTURE will contribute to understanding of the underlying biological processes involved in diseases and ageing.
To be successful in future multidisciplinary environments in Academia or Industry, ESRs need to be able to act as bridge between several diverse disciplines. Our ESRs need to overview all steps from data production via data analysis to data interpretation. In our consortium 7 academic and 4 industrial partners - experimental and theoretical - participate in research and training via teaching, offering secondments and hosting ESRs. We offer courses in high throughput methodology, genomics and statistics. Secondments will be to partners with complementary disciplines and intersectoral. Emphasis will be data management, data stewardship, entrepreneurship, and complementary skills. Interdisciplinary collaborations among ESRs will be stimulated by working on the same studies, in which new data will be generated, integrated with other datasets, analyzed with novel methods and interpreted. At the end of the project the ESRs will present and discuss their research in an integrated workshop. Our ESRs will be ready and equipped for new-generation multidisciplinary researchers. They will significantly contribute to omics research in relationship to human disease and health and knowledge translation. A conference to disseminate our work to researchers in Academia and Industry, and to stakeholders will be organized.
Champ scientifique
Programme(s)
Régime de financement
MSCA-ITN-ETN - European Training NetworksCoordinateur
LS2 9JT Leeds
Royaume-Uni