Publicaciones Peer reviewed articles (30) Cephalosporin Prodrug Inhibitors Overcome Metallo‐β‐Lactamase Driven Antibiotic Resistance Autores: Matthijs J. Haren, Kamaleddin H. M. E. Tehrani, Ioli Kotsogianni, Nicola Wade, Nora C. Brüchle, Vida Mashayekhi, Nathaniel I. Martin Publicado en: Chemistry – A European Journal, Edición 27/11, 2021, Página(s) 3806-3811, ISSN 0947-6539 Editor: John Wiley & Sons Ltd. DOI: 10.1002/chem.202004694 Polymyxin stereochemistry and its role in antibacterial activity and outer membrane disruption Autores: Nathaniel Martin; Angeliki Ioli Kotsogianni Teftsoglou; Charlotte Wesseling; Cornelis Jacob Slingerland Publicado en: ACS Infectious Diseases, 2022, ISSN 2373-8227 Editor: American Chemical Society DOI: 10.1021/acsinfecdis.2c00307 Aspergillomarasmine A inhibits metallo-β-lactamases by selectively sequestering Zn2+ Autores: David Sychantha, Caitlyn M. Rotondo, Kamaleddin H.M.E. Tehrani, Nathaniel I. Martin, Gerard D. Wright Publicado en: Journal of Biological Chemistry, Edición 297/2, 2021, Página(s) 100918, ISSN 0021-9258 Editor: American Society for Biochemistry and Molecular Biology Inc. DOI: 10.1016/j.jbc.2021.100918 Synthesis and structure-activity relationship studies of N-terminal analogues of the lipopeptide antibiotics brevicidine and laterocidine. Autores: Ross D. Ballantine; Karol Al Ayed; Samantha J. Bann; Michael Hoekstra; Nathaniel I. Martin; Stephen A. Cochrane Publicado en: RSC Medicinal Chemistry, 2022, ISSN 2632-8682 Editor: Royal Society of Chemistry DOI: 10.1039/d2md00281g Synthetic studies with the brevicidine and laterocidine lipopeptide antibiotics including analogues with enhanced properties and in vivo efficacy Autores: Karol Al Ayed; Ross D. Ballantine; Michael Hoekstra; Samantha J. Bann; Charlotte M. J. Wesseling; Alexander T. Bakker; Zheng Zhong; Yong-Xin Li; Nora C. Brüchle; Mario van der Stelt; Stephen A. Cochrane; Nathaniel I. Martin Publicado en: Chemical Science, 2022, ISSN 2041-6539 Editor: Royal Society of Chemistry DOI: 10.1039/d2sc00143h Linearization of the brevicidine and laterocidine lipopeptides yields analogues that retain full antibacterial activity Autores: Ross D. Ballantine; Karol Al Ayed; Samantha J. Bann; Michael Hoekstra; Nathaniel I. Martin; Stephen A. Cochrane Publicado en: Journal of Medicinal Chemistry, 2023, ISSN 1520-4804 Editor: American Chemical Society DOI: 10.1021/acs.jmedchem.3c00308 Structure-Activity Studies with Bis-Amidines That Potentiate Gram-Positive Specific Antibiotics against Gram-Negative Pathogens. Autores: Charlotte M J Wesseling; Cornelis J Slingerland; Shanice Veraar; Samantha Lok; Nathaniel I. Martin Publicado en: ACS Infectious Diseases, 2021, ISSN 2373-8227 Editor: American Chemical Society DOI: 10.1021/acsinfecdis.1c00466 Binding Studies Reveal Phospholipid Specificity and Its Role in the Calcium-Dependent Mechanism of Action of Daptomycin Autores: Ioli Kotsogianni; Thomas M. Wood; Francesca M. Alexander; Stephen A. Cochrane; Nathaniel I. Martin Publicado en: ACS Infectious Diseases, 2021, ISSN 2373-8227 Editor: American Chemical Society DOI: 10.1021/acsinfecdis.1c00316 Vancomycin-Polymyxin Nonapeptide conjugates that retain anti-Gram-positive activity with enhanced potency against Gram-negative strains Autores: Groesen, Emma van; Slingerland, Cornelis J.; Innocenti, Paolo; Mihajlovic, Milos; Masereeuw, Rosalinde; Martin, Nathaniel I.; Afd Chemical Biology and Drug Discovery; Afd Pharmacology; Chemical Biology and Drug Discovery; Pharmacology Publicado en: ACS Infectious Diseases, 2021, ISSN 2373-8227 Editor: American Chemical Society DOI: 10.1021/acsinfecdis.1c00318 Recent Advances in the Development of Semisynthetic Glycopeptide Antibiotics: 2014–2022 Autores: Emma van Groesen; Paolo Innocenti; Nathaniel I. Martin Publicado en: ACS Infectious Diseases, 2022, ISSN 2373-8227 Editor: American Chemical Society DOI: 10.1021/acsinfecdis.2c00253 Chemical Proteomics Reveals Antibiotic Targets of Oxadiazolones in MRSA Autores: Bakker, A.T.; Kotsogianni, A.I.; Mirenda, L.; Straub, V.M.; Avalos Garcia, M.; Berg, R.J.B.H.N. van den; Florea, B.I.; Wezel, G.P. van; Janssen, A.P.A.; Martin, N.I.; Stelt, M. van der Publicado en: Journal of the American Chemical Society, 2023, ISSN 1520-5126 Editor: American Chemical Society DOI: 10.1021/jacs.2c10819 opening the door for gram-positive specific antibiotics Autores: Nathaniel Martin; Charlotte Wesseling Publicado en: ACS Infectious Diseases, 2022, ISSN 2373-8227 Editor: American Chemical Society DOI: 10.1021/acsinfecdis.2c00193 Novel Cephalosporin Conjugates Display Potent and Selective Inhibition of Imipenemase-Type Metallo-β-Lactamases Autores: Kamaleddin H. M. E. Tehrani, Nicola Wade, Vida Mashayekhi, Nora C. Brüchle, Willem Jespers, Koen Voskuil, Diego Pesce, Matthijs J. van Haren, Gerard J. P. van Westen, Nathaniel I. Martin Publicado en: Journal of Medicinal Chemistry, Edición 64/13, 2021, Página(s) 9141-9151, ISSN 0022-2623 Editor: American Chemical Society DOI: 10.1021/acs.jmedchem.1c00362 Chimeric Peptidomimetic Antibiotic Efficiently Neutralizes Lipopolysaccharides (LPS) and Bacteria-Induced Activation of RAW Macrophages Autores: Ali Javed; Cornelis J. Slingerland; Thomas M. Wood; Nathaniel I. Martin; Femke Broere; Markus H. Weingarth; Edwin J. A. Veldhuizen Publicado en: ACS Infectious Diseases, 2023, ISSN 2373-8227 Editor: American Chemical Society DOI: 10.1021/acsinfecdis.2c00518 Metabolic labeling probes for interrogation of the host–pathogen interaction Autores: Bob J Ignacio; Thomas Bakkum; Kimberly M. Bonger; Nathaniel I. Martin; Sander I. van Kasteren Publicado en: Organic & Biomolecular Chemistry, 2021, ISSN 1477-0539 Editor: Royal Society of Chemistry DOI: 10.1039/d0ob02517h Thrombin-Derived Peptides Potentiate the Activity of Gram-Positive-Specific Antibiotics against Gram-Negative Bacteria. Autores: Charlotte M J Wesseling; Thomas M. Wood; Thomas M. Wood; Kristine Bertheussen; Samantha Lok; Nathaniel I. Martin Publicado en: Molecules, 2021, ISSN 1420-3049 Editor: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/molecules26071954 Mechanistic Investigations of Metallo‐β‐lactamase Inhibitors: Strong Zinc Binding Is Not Required for Potent Enzyme Inhibition** Autores: Nicola Wade, Kamaleddin H. M. E. Tehrani, Nora C. Brüchle, Matthijs J. Haren, Vida Mashayekhi, Nathaniel I. Martin Publicado en: ChemMedChem, Edición 16/10, 2021, Página(s) 1651-1659, ISSN 1860-7179 Editor: Wiley - V C H Verlag GmbbH & Co. DOI: 10.1002/cmdc.202100042 Synthesis and Structure-Activity Studies of β-Barrel Assembly Machine Complex Inhibitor MRL-494. Autores: Nicola Wade; Charlotte M. J. Wesseling; Paolo Innocenti; Cornelis J. Slingerland; Gregory M. Koningstein; Joen Luirink; Nathaniel I. Martin Publicado en: ACS Infectious Diseases, 2022, ISSN 2373-8227 Editor: American Chemical Society DOI: 10.1021/acsinfecdis.2c00459 Mechanistic insights into the C55-P targeting lipopeptide antibiotics revealed by structure-activity studies and high-resolution crystal structures Autores: Wood, Thomas M.; Zeronian, Matthieu R.; Buijs, Ned; Bertheussen, Kristine; Abedian, Hanieh K.; Johnson, Aidan V.; Pearce, Nicholas M.; Lutz, Martin; Kemmink, Johan; Seirsma, Tjalling; Hamoen, Leendert W.; Janssen, Bert J. C.; Martin, Nathaniel I.; Afd Chemical Biology and Drug Discovery; Sub Structural Biochemistry; Structural Biochemistry; Pharmacology Publicado en: Chemical Science, 2022, ISSN 2041-6539 Editor: Royal Society of Chemistry DOI: 10.1039/d1sc07190d β-lactam/β-lactamase inhibitor combinations: an update Autores: Kamaleddin H. M. E. Tehrani, Nathaniel I. Martin Publicado en: MedChemComm, Edición 9/9, 2018, Página(s) 1439-1456, ISSN 2040-2503 Editor: Royal Society of Chemistry DOI: 10.1039/c8md00342d Total Synthesis and Structure Assignment of the Relacidine Lipopeptide Antibiotics and Preparation of Analogues with Enhanced Stability Autores: Karol Al Ayed; Denise Zamarbide Losada; Nataliia V. Machushynets; Barbara Terlouw; Somayah S. Elsayed; Julian Schill; Vincent Trebosc; Michel Pieren; Marnix H. Medema; Gilles P. van Wezel; Nathaniel I. Martin Publicado en: ACS Infectious Diseases, 2023, ISSN 2373-8227 Editor: American Chemical Society DOI: 10.1021/acsinfecdis.3c00043 A Convenient Chemoenzymatic Preparation of Chimeric Macrocyclic Peptide Antibiotics with Potent Activity against Gram-Negative Pathogens Autores: Thomas M. Wood, Cornelis J. Slingerland, Nathaniel I. Martin Publicado en: Journal of Medicinal Chemistry, Edición 64/15, 2021, Página(s) 10890-10899, ISSN 0022-2623 Editor: American Chemical Society DOI: 10.1021/acs.jmedchem.1c00176 Synthetic Studies with Bacitracin A and Preparation of Analogues Containing Alternative Zinc Binding Groups Autores: Ned Buijs, Halana C. Vlaming, Matthijs J. van Haren, Nathaniel I. Martin Publicado en: ChemBioChem, 2022, ISSN 1439-7633 Editor: Wiley DOI: 10.1002/cbic.202200547 Synthesis and Evaluation of Polymyxins Bearing Reductively Labile Disulfide-Linked Lipids Autores: Slingerland, Cornelis J.; Wesseling, Charlotte M. J.; Innocenti, Paolo; Westphal, Koen G. C.; Masereeuw, Rosalinde; Martin, Nathaniel I.; Afd Chemical Biology and Drug Discovery; Afd Pharmacology; Chemical Biology and Drug Discovery; Pharmacology Publicado en: Journal of Medicinal Chemistry, 2022, ISSN 0022-2623 Editor: American Chemical Society DOI: 10.1021/acs.jmedchem.2c01528 The calcium-dependent lipopeptide antibiotics: structure, mechanism, & medicinal chemistry Autores: Thomas M. Wood, Nathaniel I. Martin Publicado en: MedChemComm, Edición 10/5, 2019, Página(s) 634-646, ISSN 2040-2503 Editor: Royal Society of Chemistry DOI: 10.1039/c9md00126c Aminocarboxylic acids related to aspergillomarasmine A (AMA) and ethylenediamine- N , N ′-disuccinic acid (EDDS) are strong zinc-binders and inhibitors of the metallo-beta-lactamase NDM-1 Autores: Kamaleddin H. M. E. Tehrani, Haigen Fu, Nora C. Brüchle, Vida Mashayekhi, Alejandro Prats Luján, Matthijs J. van Haren, Gerrit J. Poelarends, Nathaniel I. Martin Publicado en: Chemical Communications, Edición 56/20, 2020, Página(s) 3047-3049, ISSN 1359-7345 Editor: Royal Society of Chemistry DOI: 10.1039/d0cc00356e Dual targeting of the class V lanthipeptide antibiotic cacaoidin Autores: Julia P. Deisinger; Melina Arts; Ioli Kotsogianni; Jan-Samuel Puls; Fabian Grein; Francisco Javier Ortiz-López; Nathaniel I. Martin; Anna Müller; Olga Genilloud; Tanja Schneider Publicado en: iScience, 2023, ISSN 2589-0042 Editor: Cell Press DOI: 10.1016/j.isci.2023.106394 A β-Hairpin Epitope as Novel Structural Requirement for Protein Arginine Rhamnosylation Autores: Liubov Yakovlieva; Thomas M. Wood; Thomas M. Wood; Johan Kemmink; Ioli Kotsogianni; Franziska Koller; Juergen Lassak; Nathaniel I. Martin; Marthe T. C. Walvoort Publicado en: Chemical Science, 2021, ISSN 2041-6539 Editor: Royal Society of Chemistry DOI: 10.1039/d0sc05823h Small Molecule Carboxylates Inhibit Metallo-β-lactamases and Resensitize Carbapenem-Resistant Bacteria to Meropenem Autores: Kamaleddin H. M. E. Tehrani, Nora C. Brüchle, Nicola Wade, Vida Mashayekhi, Diego Pesce, Matthijs J. van Haren, Nathaniel I. Martin Publicado en: ACS Infectious Diseases, Edición 6/6, 2020, Página(s) 1366-1371, ISSN 2373-8227 Editor: America Chemical Society DOI: 10.1021/acsinfecdis.9b00459 The contribution of achiral residues in the laspartomycin family of calcium-dependent lipopeptide antibiotics Autores: Thomas M. Wood, Kristine Bertheussen, Nathaniel I. Martin Publicado en: Organic & Biomolecular Chemistry, Edición 18/3, 2020, Página(s) 514-517, ISSN 1477-0520 Editor: Royal Society of Chemistry DOI: 10.1039/c9ob02534k Buscando datos de OpenAIRE... Se ha producido un error en la búsqueda de datos de OpenAIRE No hay resultados disponibles
