Publikacje Peer reviewed articles (30) Cephalosporin Prodrug Inhibitors Overcome Metallo‐β‐Lactamase Driven Antibiotic Resistance Autorzy: Matthijs J. Haren, Kamaleddin H. M. E. Tehrani, Ioli Kotsogianni, Nicola Wade, Nora C. Brüchle, Vida Mashayekhi, Nathaniel I. Martin Opublikowane w: Chemistry – A European Journal, Numer 27/11, 2021, Strona(/y) 3806-3811, ISSN 0947-6539 Wydawca: John Wiley & Sons Ltd. DOI: 10.1002/chem.202004694 Polymyxin stereochemistry and its role in antibacterial activity and outer membrane disruption Autorzy: Nathaniel Martin; Angeliki Ioli Kotsogianni Teftsoglou; Charlotte Wesseling; Cornelis Jacob Slingerland Opublikowane w: ACS Infectious Diseases, 2022, ISSN 2373-8227 Wydawca: American Chemical Society DOI: 10.1021/acsinfecdis.2c00307 Aspergillomarasmine A inhibits metallo-β-lactamases by selectively sequestering Zn2+ Autorzy: David Sychantha, Caitlyn M. Rotondo, Kamaleddin H.M.E. Tehrani, Nathaniel I. Martin, Gerard D. Wright Opublikowane w: Journal of Biological Chemistry, Numer 297/2, 2021, Strona(/y) 100918, ISSN 0021-9258 Wydawca: American Society for Biochemistry and Molecular Biology Inc. DOI: 10.1016/j.jbc.2021.100918 Synthesis and structure-activity relationship studies of N-terminal analogues of the lipopeptide antibiotics brevicidine and laterocidine. Autorzy: Ross D. Ballantine; Karol Al Ayed; Samantha J. Bann; Michael Hoekstra; Nathaniel I. Martin; Stephen A. Cochrane Opublikowane w: RSC Medicinal Chemistry, 2022, ISSN 2632-8682 Wydawca: Royal Society of Chemistry DOI: 10.1039/d2md00281g Synthetic studies with the brevicidine and laterocidine lipopeptide antibiotics including analogues with enhanced properties and in vivo efficacy Autorzy: Karol Al Ayed; Ross D. Ballantine; Michael Hoekstra; Samantha J. Bann; Charlotte M. J. Wesseling; Alexander T. Bakker; Zheng Zhong; Yong-Xin Li; Nora C. Brüchle; Mario van der Stelt; Stephen A. Cochrane; Nathaniel I. Martin Opublikowane w: Chemical Science, 2022, ISSN 2041-6539 Wydawca: Royal Society of Chemistry DOI: 10.1039/d2sc00143h Linearization of the brevicidine and laterocidine lipopeptides yields analogues that retain full antibacterial activity Autorzy: Ross D. Ballantine; Karol Al Ayed; Samantha J. Bann; Michael Hoekstra; Nathaniel I. Martin; Stephen A. Cochrane Opublikowane w: Journal of Medicinal Chemistry, 2023, ISSN 1520-4804 Wydawca: American Chemical Society DOI: 10.1021/acs.jmedchem.3c00308 Structure-Activity Studies with Bis-Amidines That Potentiate Gram-Positive Specific Antibiotics against Gram-Negative Pathogens. Autorzy: Charlotte M J Wesseling; Cornelis J Slingerland; Shanice Veraar; Samantha Lok; Nathaniel I. Martin Opublikowane w: ACS Infectious Diseases, 2021, ISSN 2373-8227 Wydawca: American Chemical Society DOI: 10.1021/acsinfecdis.1c00466 Binding Studies Reveal Phospholipid Specificity and Its Role in the Calcium-Dependent Mechanism of Action of Daptomycin Autorzy: Ioli Kotsogianni; Thomas M. Wood; Francesca M. Alexander; Stephen A. Cochrane; Nathaniel I. Martin Opublikowane w: ACS Infectious Diseases, 2021, ISSN 2373-8227 Wydawca: American Chemical Society DOI: 10.1021/acsinfecdis.1c00316 Vancomycin-Polymyxin Nonapeptide conjugates that retain anti-Gram-positive activity with enhanced potency against Gram-negative strains Autorzy: Groesen, Emma van; Slingerland, Cornelis J.; Innocenti, Paolo; Mihajlovic, Milos; Masereeuw, Rosalinde; Martin, Nathaniel I.; Afd Chemical Biology and Drug Discovery; Afd Pharmacology; Chemical Biology and Drug Discovery; Pharmacology Opublikowane w: ACS Infectious Diseases, 2021, ISSN 2373-8227 Wydawca: American Chemical Society DOI: 10.1021/acsinfecdis.1c00318 Recent Advances in the Development of Semisynthetic Glycopeptide Antibiotics: 2014–2022 Autorzy: Emma van Groesen; Paolo Innocenti; Nathaniel I. Martin Opublikowane w: ACS Infectious Diseases, 2022, ISSN 2373-8227 Wydawca: American Chemical Society DOI: 10.1021/acsinfecdis.2c00253 Chemical Proteomics Reveals Antibiotic Targets of Oxadiazolones in MRSA Autorzy: Bakker, A.T.; Kotsogianni, A.I.; Mirenda, L.; Straub, V.M.; Avalos Garcia, M.; Berg, R.J.B.H.N. van den; Florea, B.I.; Wezel, G.P. van; Janssen, A.P.A.; Martin, N.I.; Stelt, M. van der Opublikowane w: Journal of the American Chemical Society, 2023, ISSN 1520-5126 Wydawca: American Chemical Society DOI: 10.1021/jacs.2c10819 opening the door for gram-positive specific antibiotics Autorzy: Nathaniel Martin; Charlotte Wesseling Opublikowane w: ACS Infectious Diseases, 2022, ISSN 2373-8227 Wydawca: American Chemical Society DOI: 10.1021/acsinfecdis.2c00193 Novel Cephalosporin Conjugates Display Potent and Selective Inhibition of Imipenemase-Type Metallo-β-Lactamases Autorzy: Kamaleddin H. M. E. Tehrani, Nicola Wade, Vida Mashayekhi, Nora C. Brüchle, Willem Jespers, Koen Voskuil, Diego Pesce, Matthijs J. van Haren, Gerard J. P. van Westen, Nathaniel I. Martin Opublikowane w: Journal of Medicinal Chemistry, Numer 64/13, 2021, Strona(/y) 9141-9151, ISSN 0022-2623 Wydawca: American Chemical Society DOI: 10.1021/acs.jmedchem.1c00362 Chimeric Peptidomimetic Antibiotic Efficiently Neutralizes Lipopolysaccharides (LPS) and Bacteria-Induced Activation of RAW Macrophages Autorzy: Ali Javed; Cornelis J. Slingerland; Thomas M. Wood; Nathaniel I. Martin; Femke Broere; Markus H. Weingarth; Edwin J. A. Veldhuizen Opublikowane w: ACS Infectious Diseases, 2023, ISSN 2373-8227 Wydawca: American Chemical Society DOI: 10.1021/acsinfecdis.2c00518 Metabolic labeling probes for interrogation of the host–pathogen interaction Autorzy: Bob J Ignacio; Thomas Bakkum; Kimberly M. Bonger; Nathaniel I. Martin; Sander I. van Kasteren Opublikowane w: Organic & Biomolecular Chemistry, 2021, ISSN 1477-0539 Wydawca: Royal Society of Chemistry DOI: 10.1039/d0ob02517h Thrombin-Derived Peptides Potentiate the Activity of Gram-Positive-Specific Antibiotics against Gram-Negative Bacteria. Autorzy: Charlotte M J Wesseling; Thomas M. Wood; Thomas M. Wood; Kristine Bertheussen; Samantha Lok; Nathaniel I. Martin Opublikowane w: Molecules, 2021, ISSN 1420-3049 Wydawca: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/molecules26071954 Mechanistic Investigations of Metallo‐β‐lactamase Inhibitors: Strong Zinc Binding Is Not Required for Potent Enzyme Inhibition** Autorzy: Nicola Wade, Kamaleddin H. M. E. Tehrani, Nora C. Brüchle, Matthijs J. Haren, Vida Mashayekhi, Nathaniel I. Martin Opublikowane w: ChemMedChem, Numer 16/10, 2021, Strona(/y) 1651-1659, ISSN 1860-7179 Wydawca: Wiley - V C H Verlag GmbbH & Co. DOI: 10.1002/cmdc.202100042 Synthesis and Structure-Activity Studies of β-Barrel Assembly Machine Complex Inhibitor MRL-494. Autorzy: Nicola Wade; Charlotte M. J. Wesseling; Paolo Innocenti; Cornelis J. Slingerland; Gregory M. Koningstein; Joen Luirink; Nathaniel I. Martin Opublikowane w: ACS Infectious Diseases, 2022, ISSN 2373-8227 Wydawca: American Chemical Society DOI: 10.1021/acsinfecdis.2c00459 Mechanistic insights into the C55-P targeting lipopeptide antibiotics revealed by structure-activity studies and high-resolution crystal structures Autorzy: Wood, Thomas M.; Zeronian, Matthieu R.; Buijs, Ned; Bertheussen, Kristine; Abedian, Hanieh K.; Johnson, Aidan V.; Pearce, Nicholas M.; Lutz, Martin; Kemmink, Johan; Seirsma, Tjalling; Hamoen, Leendert W.; Janssen, Bert J. C.; Martin, Nathaniel I.; Afd Chemical Biology and Drug Discovery; Sub Structural Biochemistry; Structural Biochemistry; Pharmacology Opublikowane w: Chemical Science, 2022, ISSN 2041-6539 Wydawca: Royal Society of Chemistry DOI: 10.1039/d1sc07190d β-lactam/β-lactamase inhibitor combinations: an update Autorzy: Kamaleddin H. M. E. Tehrani, Nathaniel I. Martin Opublikowane w: MedChemComm, Numer 9/9, 2018, Strona(/y) 1439-1456, ISSN 2040-2503 Wydawca: Royal Society of Chemistry DOI: 10.1039/c8md00342d Total Synthesis and Structure Assignment of the Relacidine Lipopeptide Antibiotics and Preparation of Analogues with Enhanced Stability Autorzy: Karol Al Ayed; Denise Zamarbide Losada; Nataliia V. Machushynets; Barbara Terlouw; Somayah S. Elsayed; Julian Schill; Vincent Trebosc; Michel Pieren; Marnix H. Medema; Gilles P. van Wezel; Nathaniel I. Martin Opublikowane w: ACS Infectious Diseases, 2023, ISSN 2373-8227 Wydawca: American Chemical Society DOI: 10.1021/acsinfecdis.3c00043 A Convenient Chemoenzymatic Preparation of Chimeric Macrocyclic Peptide Antibiotics with Potent Activity against Gram-Negative Pathogens Autorzy: Thomas M. Wood, Cornelis J. Slingerland, Nathaniel I. Martin Opublikowane w: Journal of Medicinal Chemistry, Numer 64/15, 2021, Strona(/y) 10890-10899, ISSN 0022-2623 Wydawca: American Chemical Society DOI: 10.1021/acs.jmedchem.1c00176 Synthetic Studies with Bacitracin A and Preparation of Analogues Containing Alternative Zinc Binding Groups Autorzy: Ned Buijs, Halana C. Vlaming, Matthijs J. van Haren, Nathaniel I. Martin Opublikowane w: ChemBioChem, 2022, ISSN 1439-7633 Wydawca: Wiley DOI: 10.1002/cbic.202200547 Synthesis and Evaluation of Polymyxins Bearing Reductively Labile Disulfide-Linked Lipids Autorzy: Slingerland, Cornelis J.; Wesseling, Charlotte M. J.; Innocenti, Paolo; Westphal, Koen G. C.; Masereeuw, Rosalinde; Martin, Nathaniel I.; Afd Chemical Biology and Drug Discovery; Afd Pharmacology; Chemical Biology and Drug Discovery; Pharmacology Opublikowane w: Journal of Medicinal Chemistry, 2022, ISSN 0022-2623 Wydawca: American Chemical Society DOI: 10.1021/acs.jmedchem.2c01528 The calcium-dependent lipopeptide antibiotics: structure, mechanism, & medicinal chemistry Autorzy: Thomas M. Wood, Nathaniel I. Martin Opublikowane w: MedChemComm, Numer 10/5, 2019, Strona(/y) 634-646, ISSN 2040-2503 Wydawca: Royal Society of Chemistry DOI: 10.1039/c9md00126c Aminocarboxylic acids related to aspergillomarasmine A (AMA) and ethylenediamine- N , N ′-disuccinic acid (EDDS) are strong zinc-binders and inhibitors of the metallo-beta-lactamase NDM-1 Autorzy: Kamaleddin H. M. E. Tehrani, Haigen Fu, Nora C. Brüchle, Vida Mashayekhi, Alejandro Prats Luján, Matthijs J. van Haren, Gerrit J. Poelarends, Nathaniel I. Martin Opublikowane w: Chemical Communications, Numer 56/20, 2020, Strona(/y) 3047-3049, ISSN 1359-7345 Wydawca: Royal Society of Chemistry DOI: 10.1039/d0cc00356e Dual targeting of the class V lanthipeptide antibiotic cacaoidin Autorzy: Julia P. Deisinger; Melina Arts; Ioli Kotsogianni; Jan-Samuel Puls; Fabian Grein; Francisco Javier Ortiz-López; Nathaniel I. Martin; Anna Müller; Olga Genilloud; Tanja Schneider Opublikowane w: iScience, 2023, ISSN 2589-0042 Wydawca: Cell Press DOI: 10.1016/j.isci.2023.106394 A β-Hairpin Epitope as Novel Structural Requirement for Protein Arginine Rhamnosylation Autorzy: Liubov Yakovlieva; Thomas M. Wood; Thomas M. Wood; Johan Kemmink; Ioli Kotsogianni; Franziska Koller; Juergen Lassak; Nathaniel I. Martin; Marthe T. C. Walvoort Opublikowane w: Chemical Science, 2021, ISSN 2041-6539 Wydawca: Royal Society of Chemistry DOI: 10.1039/d0sc05823h Small Molecule Carboxylates Inhibit Metallo-β-lactamases and Resensitize Carbapenem-Resistant Bacteria to Meropenem Autorzy: Kamaleddin H. M. E. Tehrani, Nora C. Brüchle, Nicola Wade, Vida Mashayekhi, Diego Pesce, Matthijs J. van Haren, Nathaniel I. Martin Opublikowane w: ACS Infectious Diseases, Numer 6/6, 2020, Strona(/y) 1366-1371, ISSN 2373-8227 Wydawca: America Chemical Society DOI: 10.1021/acsinfecdis.9b00459 The contribution of achiral residues in the laspartomycin family of calcium-dependent lipopeptide antibiotics Autorzy: Thomas M. Wood, Kristine Bertheussen, Nathaniel I. Martin Opublikowane w: Organic & Biomolecular Chemistry, Numer 18/3, 2020, Strona(/y) 514-517, ISSN 1477-0520 Wydawca: Royal Society of Chemistry DOI: 10.1039/c9ob02534k Wyszukiwanie danych OpenAIRE... Podczas wyszukiwania danych OpenAIRE wystąpił błąd Brak wyników
