Understanding and Controlling Glycosylation Reactions

Informazioni relative al progetto

GLYCONTROL

ID dell’accordo di sovvenzione: 726072

DOI

10.3030/726072

Progetto chiuso

Data della firma CE 20 Febbraio 2017

Data di avvio 1 Maggio 2017

Data di completamento 31 Ottobre 2022

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 2 000 000,00

Contributo UE

€ 2 000 000,00

Coordinato da

UNIVERSITEIT LEIDEN
Netherlands

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (20)

Reactivity-Stereoselectivity Mapping for the Assembly of Mycobacterium Marinum Lipooligosaccharides

Autori: Thomas Hansen; Tim P Ofman; Joey G C Vlaming; Ivan A. Gagarinov; Jessey van Beek; Tessa A Goté; Jacoba M Tichem; Gijs Ruijgrok; Herman S. Overkleeft; Dmitri V. Filippov; Gijsbert A. van der Marel; Jeroen D. C. Codée
Pubblicato in: Angewandte Chemie, Numero 4 January 2020,133, 2, 2020, Pagina/e 950-958, ISSN 0044-8249
Editore: John Wiley & Sons, Ltd
DOI: 10.1002/anie.202010280

Characterization of glycosyl dioxolenium ions and their role in glycosylation reactions

Autori: Hansen T., Elferink H., Hengst J.M.A. van, Houthuijs K.J., Remmerswaal W.A., Kromm A., Berden G., Vorm S. van der, Rijs A.M., Overkleeft H.S., Filippov D.V., Rutjes F.P.J.T., Marel G.A. van der, Martens J., Oomens J., Codée J.D.C., Boltje T.J.
Pubblicato in: Nature Communications, Numero 11, 2664, 29 May 2020, 2020, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-020-16362-x

Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation

Autori: Bamford N.C., Mauff F. Le, Loon J.C. van, Ostapska H., Snarr B.D., Zhang Y., Kitova E.N., Klassen J.S., Codee J.D.C., Sheppard D.C., Howell P.L.
Pubblicato in: Nature Communications, Numero 11, 2450 15 May 2020, 2022, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-020-16144-5

Reagent controlled stereoselective synthesis of teichoic acid α-(1,2)-glucans

Autori: Liming Wang; Francesca Berni; Jacopo Enotarpi; Hermen S. Overkleeft; Gijs A. van der Marel; Jeroen D. C. Codée
Pubblicato in: Organic & Biomolecular Chemistry, Numero 18, 27 February 2020, 2020, Pagina/e 2038-2050, ISSN 1477-0520
Editore: Royal Society of Chemistry
DOI: 10.1039/d0ob00240b

Halogen atom participation in guiding the stereochemical outcomes of acetal substitution reactions

Autori: Demkiw, K.M.; Remmerswaal, W.A.; Hansen, T.; Marel, G.A. van der; Codee, J.D.C.; Woerpel, K.A.
Pubblicato in: Angewandte Chemie, Numero 16 september 2022, 134, 42, 2022, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202209401

Mapping the effect of configuration and protecting group pattern on glycosyl acceptor reactivity

Autori: Jacob van Hengst, Rik Hellemons, Wouter A. Remmerswaal, Koen van de Vrande, Thomas Hansen, Stefan van der Vorm, Herman S. Overkleeft, Gijs van der marel and Jeroen D Codee
Pubblicato in: Chemical Science, 2023, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/d2sc06139b

An Orthogonally Protected Cyclitol for the Construction of Nigerose- and Dextran-Mimetic Cyclophellitols.

Autori: Tim P Ofman; Florian Küllmer; Gijsbert A. van der Marel; Jeroen D. C. Codée; Herman S. Overkleeft
Pubblicato in: Organic Letters, Numero 23(24), November 30 , 2021, 2021, Pagina/e 9516 - 9519, ISSN 1523-7060
Editore: American Chemical Society
DOI: 10.1021/acs.orglett.1c03723

Reagent Controlled Stereoselective Synthesis of α-Glucans

Autori: Liming Wang, Herman S. Overkleeft, Gijsbert A. van der Marel, Jeroen D. C. Codée
Pubblicato in: Journal of the American Chemical Society, Numero 140/13, 2018, Pagina/e 4632-4638, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.8b00669

Mapping the Relationship between Glycosyl Acceptor Reactivity and Glycosylation Stereoselectivity

Autori: Stefan van der Vorm, Jacob M. A. van Hengst, Marloes Bakker, Herman S. Overkleeft, Gijsbert A. van der Marel, Jeroen D. C. Codée
Pubblicato in: Angewandte Chemie International Edition, Numero 57/27, 2018, Pagina/e 8240-8244, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201802899

Reagent Controlled Stereoselective Assembly of α-(1,3)-Glucans

Autori: Liming Wang, Herman S. Overkleeft, Gijsbert A. van der Marel, Jeroen D. C. Codée
Pubblicato in: European Journal of Organic Chemistry, Numero 2019/10, 2019, Pagina/e 1994-2003, ISSN 1434-193X
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/ejoc.201800894

Defining the S N 1 Side of Glycosylation Reactions: Stereoselectivity of Glycopyranosyl Cations

Autori: Thomas Hansen, Ludivine Lebedel, Wouter A. Remmerswaal, Stefan van der Vorm, Dennis P. A. Wander, Mark Somers, Herman S. Overkleeft, Dmitri V. Filippov, Jérôme Désiré, Agnès Mingot, Yves Bleriot, Gijsbert A. van der Marel, Sebastien Thibaudeau, Jeroen D. C. Codée
Pubblicato in: ACS Central Science, 2019, ISSN 2374-7943
Editore: ACS
DOI: 10.1021/acscentsci.9b00042

Ega3 from the fungal pathogen Aspergillus fumigatus is an endo-α-1,4-galactosaminidase that disrupts microbial biofilms

Autori: Natalie C. Bamford, François Le Mauff, Adithya S. Subramanian, Patrick Yip, Claudia Millán, Yongzhen Zhang, Caitlin Zacharias, Adam Forman, Mark Nitz, Jeroen D. C. Codée, Isabel Usón, Donald C. Sheppard, P. Lynne Howell
Pubblicato in: Journal of Biological Chemistry, Numero 294/37, 2019, Pagina/e 13833-13849, ISSN 0021-9258
Editore: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/jbc.ra119.009910

Acceptor reactivity in glycosylation reactions

Autori: Stefan van der Vorm, Thomas Hansen, Jacob M. A. van Hengst, Herman S. Overkleeft, Gijsbert A. van der Marel, Jeroen D. C. Codée
Pubblicato in: Chemical Society Reviews, Numero 48/17, 2019, Pagina/e 4688-4706, ISSN 0306-0012
Editore: Royal Society of Chemistry
DOI: 10.1039/c8cs00369f

Molecular mechanism of Aspergillus fumigatus biofilm disruption by fungal and bacterial glycoside hydrolases

Autori: François Le Mauff, Natalie C. Bamford, Noor Alnabelseya, Yongzhen Zhang, Perrin Baker, Howard Robinson, Jeroen D. C. Codée, P. Lynne Howell, Donald C. Sheppard
Pubblicato in: Journal of Biological Chemistry, Numero 294/28, 2019, Pagina/e 10760-10772, ISSN 0021-9258
Editore: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/jbc.ra119.008511

Cover Picture: Mapping the Relationship between Glycosyl Acceptor Reactivity and Glycosylation Stereoselectivity (Angew. Chem. Int. Ed. 27/2018)

Autori: Stefan van der Vorm, Jacob M. A. van Hengst, Marloes Bakker, Herman S. Overkleeft, Gijsbert A. van der Marel, Jeroen D. C. Codée
Pubblicato in: Angewandte Chemie International Edition, Numero 57/27, 2018, Pagina/e 7905-7905, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201804576

Reagent Controlled Glycosylations for the Assembly of Well-Defined Pel Oligosaccharides

Autori: Liming Wang, Yongzhen Zhang, Herman S. Overkleeft, Gijsbert A. van der Marel, Jeroen D. C. Codée
Pubblicato in: The Journal of Organic Chemistry, 2020, ISSN 0022-3263
Editore: American Chemical Society
DOI: 10.1021/acs.joc.0c00703

Assembly of a Library of Pel-Oligosaccharides Featuring α-Glucosamine and α-Galactosamine Linkages

Autori: Yongzhen Zhang; Liming Wang; Liming Wang; Herman S. Overkleeft; Gijsbert A. van der Marel; Jeroen D. C. Codée
Pubblicato in: Frontiers in Chemistry, Numero 26 January 2022, 10:842238, 2022, ISSN 2296-2646
Editore: Frontiers
DOI: 10.3389/fchem.2022.842238

Synthesis and antibody binding studies of schistosome-derived oligo-α-(1-2)-l-fucosides

Autori: Michael R. Harvey; Fabrizio Chiodo; Fabrizio Chiodo; Wouter Noest; Cornelis H. Hokke; Gijsbert A. van der Marel; Jeroen D. C. Codée
Pubblicato in: Molecules, Numero 26 (8), 2246, 13 April 2021, 2021, ISSN 1420-3049
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules26082246

Synthesis and Structural Analysis of Aspergillus fumigatus Galactosaminogalactans Featuring α-Galactose, α-Galactosamine and α-N-Acetyl Galactosamine Linkages

Autori: Yongzhen Zhang; Marcos Gómez-Redondo; Gonzalo Jiménez-Osés; Ana Ardá; Herman S. Overkleeft; Gijsbert A. van der Marel; Jesús Jiménez-Barbero; Jeroen D. C. Codée
Pubblicato in: Angewandte Chemie, Numero 132, 28 April 2020, 2020, Pagina/e 12746-12750, ISSN 0044-8249
Editore: John Wiley & Sons Ltd
DOI: 10.1002/ange.202003951

How Lewis Acids Catalyze Ring-Openings of Cyclohexene Oxide

Autori: Hansen, T.; Vermeeren, P.; Yoshisada, R.; Filippov, D.V.; Marel, G.A. van der; Codee, J.D.C.; Hamlin, T.A.
Pubblicato in: The journal of Organic Chemistry, Numero 86,4, 4 February 2021, 2021, Pagina/e 3565-3573, ISSN 0022-3263
Editore: American Chemical Society
DOI: 10.1021/acs.joc.0c02955