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Towards enduring mouse resources and services advancing research into human health and disease

Descrizione del progetto

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Risorse sostenibili di modelli murini per la ricerca biomedica

I modelli murini svolgono un ruolo fondamentale nella ricerca biomedica, essendo strumenti preziosi per studiare le malattie umane, indagare le funzioni genetiche e testare potenziali interventi terapeutici. I loro cicli riproduttivi brevi e la capacità di essere manipolati geneticamente li rendono un potente organismo modello. Il progetto INFRAFRONTIER2020, finanziato dall’UE, intende garantire l’accesso ai modelli murini espandendo la rete INFRAFRONTIER di infrastrutture di ricerca, agevolando il coinvolgimento dell’industria e di consorzi globali per le attività di collaborazione. Il progetto svilupperà modelli aziendali, un quadro giuridico e servizi personalizzati, oltre a portare avanti una sensibilizzazione in questo ambito per garantire la sostenibilità a lungo termine della rete.

Obiettivo

The INFRAFRONTIER RI integrates European Mouse Clinics and the European Mouse Mutant Archive with the common goal to ensure access to mouse models for basic research of human health and disease, and to translate this knowledge into therapeutic approaches for the benefit of the European society.

The expanded INFRAFRONTIER2020 network, coordinated by the INFRAFRONTIER GmbH, includes 3 SMEs and is strategically responding to the INFRADEV3 call with aligned objectives to advance the long-term sustainability which are 1) development of business models and a stable legal framework; 2) raise awareness of the INFRAFRONTIER RI; 3) provide bespoke services aligned with user demands; 4) promote best practices in mouse phenogenomics; 5) enhance robustness of the INFRAFRONTIER IT infrastructure and use of the EMMA strain resource; and 6) improve business processes. Towards achieving these objectives key INFRAFRONTIER2020 project deliverables are:

• INFRAFRONTIER Business Plan2.0 and business models for all services
• Stable legal framework built on the INFRAFRONTIER legal entity
• INFRAFRONTIER annual stakeholder conferences
• Customised mouse model and secondary phenotyping pilot services
• INFRAFRONTIER advanced training schools in mouse phenogenomics
• Reengineered EMMA Database2.0 system
• Annotated mouse models of human diseases
• Quality management system for the legal entity

INFRAFRONTIER2020 will 1) enhance the sustainable operation of the INFRAFRONTIER RI; 2) continue to structure the ERA, 3) foster innovation, and 4) address major societal challenges in human health by customised service pilots supporting research into common and rare diseases. A sustainable INFRAFRONTIER RI will ensure the quality of deposited mice and support the reproducibility of biological results. Outreach efforts will raise awareness of resources and services and facilitate sustainable engagement with industry and global consortia such as the International Mouse Phenotyping Consortium

Campo scientifico

Parole chiave

Programma(i)

Argomento(i)

Invito a presentare proposte

H2020-INFRADEV-2016-2017

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Bando secondario

H2020-INFRADEV-2016-1

Meccanismo di finanziamento

CSA - Coordination and support action

Coordinatore

INFRAFRONTIER GMBH
Contribution nette de l'UE
€ 1 713 235,00
Indirizzo
INGOLSTADTER LANDSTRASSE 1
85764 Neuherberg
Germania

Mostra sulla mappa
Regione
Bayern Oberbayern München, Landkreis
Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Collegamenti
Costo totale
€ 1 713 235,00

Partecipanti (28)

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Ultimo aggiornamento: 14 Settembre 2023

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Permalink: https://cordis.europa.eu/project/id/730879/it

European Union, 2024