Skip to main content
European Commission logo
italiano italiano
CORDIS - Risultati della ricerca dell’UE
CORDIS
CORDIS Web 30th anniversary CORDIS Web 30th anniversary

REgenerative therapy of intervertebral disc: a double blind phase 2b trial of intradiscal injection of mesenchymal stromal cells in degenerative disc disease of the lomber SPINE unresponsive to conventional therapy

Risultati finali

RESPINE final clinical trial report
Report describing the role of miRNAs in regulating the immunosuppressive capacity of human MSCs
Midterm recruitment report
Dissemination and Communication

CHUM will be prepared logo, poster, video, brochure and website

Report describing the profile of inflammatory markers and cytokine meditators that contribute to the inflammatory nature of the degenerated disc
Registration of clinical trial on EudraCT and Clinicaltrials.gov

Registration of clinical trial on EudraCT and Clinicaltrials.gov. Transfer the register number to the european comission

Report describing the identification of inflammatory mediators capable of “licensing”: MSCs in vitro
Minutes of the Meeting with complementary projects

A Meeting with representatives from these and any other complementary projects will be set-up in M24 to discuss and exchange best-practices regarding scientific, standardisation, economic and regulatory issues related to projects’ results. Networking and exchange of best practices with similar initiatives will also take place throughout the project at conferences and other events.

"Report describing the functional effects of ""licensed"" allogeneic MSCs on the activation of T cells and macrophages in vitro"

Report describing the functional effects of licensed allogeneic MSCs on the activation of T cells and macrophages in vitro

RESPINE final workshop

RESPINE workshops will be organized the final workshop in M78 by CHUM The target audience will include scientists clinicians pathologists members of standards working groups patient groups future potential partners investors students and regulators

RESPINE midterm workshop

RESPINE workshops will be organized at M24 by UCBMThe target audience will include scientists clinicians pathologists members of standards working groups patient groups future potential partners investors students and regulators The RESPINE clinical study its evaluation and impacts will be presented along with the database

Pubblicazioni

Mesenchymal Stem Cell-Derived Exosomes: The New Frontier for the Treatment of Intervertebral Disc Degeneration

Autori: Veronica Tilotta, Gianluca Vadalà ,Luca Ambrosio, Fabrizio Russo, Claudia Cicione, Giuseppina Di Giacomo, Rocco Papalia andVincenzo Denaro
Pubblicato in: Applied Sciences, 2021, ISSN 2076-3417
Editore: MDPI
DOI: 10.3390/app112311222

miR-155 Contributes to the Immunoregulatory Function of Human Mesenchymal Stem Cells

Autori: Yves-Marie Pers, Claire Bony, Isabelle Duroux-Richard, Laurène Bernard, Marie Maumus, Said Assou, Frank Barry, Christian Jorgensen, Danièle Noël
Pubblicato in: Frontiers in Immunology, Numero 12, 2021, ISSN 1664-3224
Editore: frontiersin
DOI: 10.3389/fimmu.2021.624024

Mesenchymal Stromal Cell-Derived Extracellular Vesicles Regulate the Mitochondrial Metabolism via Transfer of miRNAs

Autori: Claire Loussouarn, Yves-Marie Pers, Claire Bony, Christian Jorgensen, Danièle Noël
Pubblicato in: Frontiers in Immunology, Numero 12, 2021, ISSN 1664-3224
Editore: frontiersin
DOI: 10.3389/fimmu.2021.623973

Combinatorial conditioning of adipose derived‐mesenchymal stem cells enhances their neurovascular potential: Implications for intervertebral disc degeneration

Autori: Abbie. L. A. Binch, Stephen M. Richardson, Judith A. Hoyland, Frank P. Barry
Pubblicato in: JOR SPINE, Numero 2/4, 2019, ISSN 2572-1143
Editore: JOR SPINE
DOI: 10.1002/jsp2.1072

A Hyaluronan and Platelet-Rich Plasma Hydrogel for Mesenchymal Stem Cell Delivery in the Intervertebral Disc: An Organ Culture Study

Autori: Fabrizio Russo, Luca Ambrosio, Marianna Peroglio, Wei Guo, Sebastian Wangler, Jan Gewiess, Sibylle Grad, Mauro Alini, Rocco Papalia, Gianluca Vadalà, Vincenzo Denaro
Pubblicato in: International Journal of Molecular Sciences, Numero 22/6, 2021, Pagina/e 2963, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22062963

È in corso la ricerca di dati su OpenAIRE...

Si è verificato un errore durante la ricerca dei dati su OpenAIRE

Nessun risultato disponibile