Biomaterials and Additive Manufacturing: Osteochondral Scaffold innovation applied to osteoarthritis

Risultati finali

Report on the clinical procedure and deliver method

Report containing clinical precedures the implant the scaffold into the defects and developed protocols for clinical delivery.

Report on state of the art of osteochondral scaffolds and patent

State of the art and patent search about osteochondral scaffolds.

Mid-term meeting

As described in the article 19 of the GAP, the coordinator must organise a mid-term meeting between the beneficiaries, the partner organisation(s) and the Agency

Report on dissemination and communication

Report including all dissemination and communication events carried out by partners along the project

Pubblicazioni

Synergistic interactions between wear and corrosion of Ti-16Mo orthopedic alloy

Autori: Wei Xu, Aihua Yu, Xin Lu, Maryam Tamaddon, Liqi Ng, Muhammad dilawer Hayat, Mengdi Wang, Jianliang Zhang, Xuanhui Qu, Chaozong Liu
Pubblicato in: Journal of Materials Research and Technology, Numero 9/5, 2020, Pagina/e 9996-10003, ISSN 2238-7854
Editore: Elsevier Editora Ltda
DOI: 10.1016/j.jmrt.2020.06.095

Polycaprolactone–carboxymethyl cellulose composites for manufacturing porous scaffolds by material extrusion

Autori: M. E. Alemán-Domínguez, Z. Ortega, A. N. Benítez, Mario Monzón, L. V. Garzón, Sara Ajami, Chaozong Liu
Pubblicato in: Bio-Design and Manufacturing, Numero 1/4, 2018, Pagina/e 245-253, ISSN 2096-5524
Editore: Springer
DOI: 10.1007/s42242-018-0024-z

Bilayered scaffold with 3D printed stiff subchondral bony compartment to provide constant mechanical support for long-term cartilage regeneration

Autori: Yang, T; Tamaddon, M; Jiang, L; Wang, J; Liu, Z; Liu, Z; Meng, H; Hu, Y; Gao, J; Yang, X; Zhao, Y; Wang, Y; Wang, A; Wu, Q; Liu, C; Peng, J; Sun, X; Xue, Q
Pubblicato in: Journal of Orthopaedic Translation, 2021, ISSN 2214-031X
Editore: ELSEVIER
DOI: 10.1016/j.jot.2021.09.001

Substitution for In Vitro and In Vivo Tests: Computational Models from Cell Attachment to Tissue Regeneration

Autori: Huang, H.; Liu, C.; Yi, T.; Tamaddon, M.; Yuan, S.; Shi, Z.; Liu, Z.
Pubblicato in: Chinese Medical Sciences Journal, 2021, ISSN 1001-9294
Editore: Taylor & Francis
DOI: 10.24920/004007

TiO2 Nanotopography-Driven Osteoblast Adhesion through Coulomb’s Force Evolution

Autori: Luo, J.; Zhao, S.; Gao, X.; Varma, S.N.; Xu, W.; Tamaddon, M.; Thorogate, R.; Yu, H.; Lu, X.; Salmeron-Sanchez, M.; Liu, C.
Pubblicato in: ACS Applied Materials & Interfaces, Numero 19448252, 2022, ISSN 1944-8252
Editore: American Chemical Society
DOI: 10.1021/acsami.2c07652

Characteristics of novel Ti–10Mo-xCu alloy by powder metallurgy for potential biomedical implant applications

Autori: Wei Xu, Chenjin Hou, Yuxuan Mao, Lei Yang, Maryam Tamaddon, Jianliang Zhang, Xuanhui Qu, Chaozong Liu, Bo Su, Xin Lu
Pubblicato in: Bioactive Materials, Numero 5/3, 2020, Pagina/e 659-666, ISSN 2452-199X
Editore: Elsevier
DOI: 10.1016/j.bioactmat.2020.04.012

The Optimization of Ti Gradient Porous Structure Involves the Finite Element Simulation Analysis

Autori: Liu, B.; Xu, W.; Lu, X.; Tamaddon, M.; Chen, M.; Dong, J.; Liu, Y.; Guo, L.; Zhang, J.; Qu, X.; He, X.; Liu, C.
Pubblicato in: Frontiers in Materials, 2021, ISSN 2296-8016
Editore: FRONTIERS MEDIA SA
DOI: 10.3389/fmats.2021.642135

Eularian wall film model for predicting dynamic cell culture process to evaluate scaffold design in a perfusion bioreactor

Autori: Liu, Z.; Tao, C.; Yuan, S.; Wang, W.; Tamaddon, M.; Ng, L.; Huang, H.; Sun, X.; Liu, C.
Pubblicato in: Medicine in Novel Technology and Devices, 2022, ISSN 2590-0935
Editore: Elsevier
DOI: 10.1016/j.medntd.2021.100104

Micro-Computed Tomography Analysis of Subchondral Bone Regeneration Using Osteochondral Scaffolds in an Ovine Condyle Model

Autori: Flaherty, T.; Tamaddon, M.; Liu, C.
Pubblicato in: Applied Sciences, 2021, ISSN 2076-3417
Editore: MDPI
DOI: 10.3390/app11030891

Comparison of CAD and Voxel-Based Modelling Methodologies for the Mechanical Simulation of Extrusion-Based 3D Printed Scaffolds

Autori: Vega, G.; Paz, R.; Gleadall, A.; Monzón, M.; Alemán-Domínguez, M.E.
Pubblicato in: Materials, 2021, ISSN 1996-1944
Editore: MDPI Open Access Publishing
DOI: 10.3390/ma14195670

Advances on gradient scaffolds for osteochondral tissue engineering

Autori: Oliveira, J.M.; Ribeiro, V.P.; Reis, R.L.
Pubblicato in: Progress in Biomedical Engineering, 2021, ISSN 2516-1091
Editore: IOP Publishing
DOI: 10.1088/2516-1091/abfc2c

Sheep condyle model evaluation of bone marrow cell concentrate combined with a scaffold for repair of large osteochondral defects

Autori: Tamaddon, M.; Blunn, G.; Xu, W.; Alemán Domínguez, M.E.; Monzón, M.; Donaldson, J.; Skinner, J.; Arnett, T.R.; Wang, L.; Liu, C.
Pubblicato in: Bone & Joint Research, 2021, ISSN 2046-3758
Editore: BRITISH EDITORIAL SOC BONE & JOINT SURGERY
DOI: 10.1302/2046-3758.1010.bjr-2020-0504.r1

Functionally graded additive manufacturing to achieve functionality specifications of osteochondral scaffolds

Autori: Mario Monzón, Chaozong Liu, Sara Ajami, Miguel Oliveira, Ricardo Donate, Viviana Ribeiro, Rui L. Reis
Pubblicato in: Bio-Design and Manufacturing, Numero 1/1, 2018, Pagina/e 69-75, ISSN 2096-5524
Editore: Springer
DOI: 10.1007/s42242-018-0003-4

Biomaterials and additive manufacturing: osteochondral scaffold innovation applied to osteoarthritis (BAMOS project)

Autori: Mario Monzón
Pubblicato in: Journal of Zhejiang University-SCIENCE A, Numero 19/4, 2018, Pagina/e 329-330, ISSN 1673-565X
Editore: Zhejiang University Press
DOI: 10.1631/jzus.a18nw001

Current advances in solid free-form techniques for osteochondral tissue engineering

Autori: João Bebiano Costa, Joana Silva-Correia, Rui Luís Reis, Joaquim Miguel Oliveira
Pubblicato in: Bio-Design and Manufacturing, Numero 1/3, 2018, Pagina/e 171-181, ISSN 2096-5524
Editore: Springer
DOI: 10.1007/s42242-018-0017-y

Osteochondral tissue repair in osteoarthritic joints: clinical challenges and opportunities in tissue engineering

Autori: Maryam Tamaddon, Ling Wang, Ziyu Liu, Chaozong Liu
Pubblicato in: Bio-Design and Manufacturing, Numero 1/2, 2018, Pagina/e 101-114, ISSN 2096-5524
Editore: Springer
DOI: 10.1007/s42242-018-0015-0

Comparison of low-pressure oxygen plasma and chemical treatments for surface modifications of Ti6Al4V

Autori: María Elena Alemán-Domínguez, Zaida Ortega, Antonio N. Benítez, Aday Romero-Pérez, Ling Wang, Ruymán Santana-Farré, Francisco Rodríguez-Esparragón
Pubblicato in: Bio-Design and Manufacturing, 2019, ISSN 2096-5524
Editore: Springer
DOI: 10.1007/s42242-019-00036-9

Fretting corrosion of screws contribute to the fixation failure of the femoral neck: a case report

Autori: Jiajun Luo, Sara Ajami, Hai-Ming Yu, Shuanhong Ma, Shen-Mao Chen, Feng Zhou, Pei-Wen Wang, Xue-Dong Yao, Chaozong Liu
Pubblicato in: Biosurface and Biotribology, Numero 5/4, 2019, Pagina/e 118-123, ISSN 2405-4518
Editore: Institution of Engineering and Technology (IET)
DOI: 10.1049/bsbt.2019.0008

Evaluation of Aloe Vera Coated Polylactic Acid Scaffolds for Bone Tissue Engineering

Autori: Ricardo Donate, María Elena Alemán-Domínguez, Mario Monzón, Jianshu Yu, Francisco Rodríguez-Esparragón, Chaozong Liu
Pubblicato in: Applied Sciences, Numero 10/7, 2020, Pagina/e 2576, ISSN 2076-3417
Editore: MDPI
DOI: 10.3390/app10072576

Hierarchical HRP-Crosslinked Silk Fibroin/ZnSr-TCP Scaffolds for Osteochondral Tissue Regeneration: Assessment of the Mechanical and Antibacterial Properties

Autori: Viviana P. Ribeiro, Sandra Pina, Sabina Gheduzzi, Ana C. Araújo, Rui L. Reis, Joaquim M. Oliveira
Pubblicato in: Frontiers in Materials, Numero 7, 2020, ISSN 2296-8016
Editore: Frontiers Media
DOI: 10.3389/fmats.2020.00049

Translation through collaboration: practice applied in BAMOS project in in vivo testing of innovative osteochondral scaffolds

Autori: Ricardo Donate; Maryam Tamaddon; Viviana Ribeiro; Mario Monzón; J. Miguel Oliveira; Chaozong Liu
Pubblicato in: Biomaterials Translational, Numero 3/2, 2022, ISSN 2096-112X
Editore: Chinese Medical Association
DOI: 10.12336/biomatertransl.2022.02.003

Determination of an Initial Stage of the Bone Tissue Ingrowth Into Titanium Matrix by Cell Adhesion Model

Autori: Liu, Z.; Tamaddon, M.; Chen, S.M.; Wang, H.; San Cheong, V.; Gang, F.; Sun, X.; Liu, C.
Pubblicato in: Frontiers in Bioengineering and Biotechnology, 2021, ISSN 2296-4185
Editore: FRONTIERS MEDIA SA
DOI: 10.3389/fbioe.2021.736063

Design and performance evaluation of additively manufactured composite lattice structures of commercially pure Ti (CP–Ti)

Autori: Wei Xu, Aihua Yu, Xin Lu, Maryam Tamaddon, Mengdi Wang, Jiazhen Zhang, Jianliang Zhang, Xuanhui Qu, Chaozong Liu, Bo Su
Pubblicato in: Bioactive Materials, Numero 6/5, 2021, Pagina/e 1215-1222, ISSN 2452-199X
Editore: Elsevier
DOI: 10.1016/j.bioactmat.2020.10.005

Cell Seeding Process Experiment and Simulation on Three-Dimensional Polyhedron and Cross-Link Design Scaffolds

Autori: Ziyu Liu, Maryam Tamaddon, Yingying Gu, Jianshu Yu, Nan Xu, Fangli Gang, Xiaodan Sun, Chaozong Liu
Pubblicato in: Frontiers in Bioengineering and Biotechnology, Numero 8, 2020, ISSN 2296-4185
Editore: Frontiers Media SA
DOI: 10.3389/fbioe.2020.00104

In vivo evaluation of additively manufactured multi-layered scaffold for the repair of large osteochondral defects

Autori: Tamaddon, Maryam; Blunn, Gordon; Tan, Rongwei; Yang, Pan; Sun, Xiaodan; Chen, Shen-Mao; Luo, Jiajun; Liu, Ziyu; Wang, Ling; Li, Dichen; Donate, Ricardo; Monzón, Mario; Liu, Chaozong
Pubblicato in: Bio-Design and Manufacturing, 2022, ISSN 2522-8552
Editore: Springer
DOI: 10.1007/s42242-021-00177-w

Bioinspired Silk Fibroin-Based Composite Grafts as Bone Tunnel Fillers for Anterior Cruciate Ligament Reconstruction

Autori: Ribeiro V.P., Costa J.B., Carneiro S.M., Pina S., Veloso A.C.A., Reis R.L., and Oliveira J.M.
Pubblicato in: Pharmaceutics, Numero 19994923, 2022, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14040697

Nano-Modified Titanium Implant Materials: A Way Toward Improved Antibacterial Properties

Autori: Liu, J; Liu, J; Attarilar, S; Wang, C; Tamaddon, M; Yang, C; Xie, K; Yao, J; Wang, L; Liu, C; Tang, Y
Pubblicato in: Frontiers in Bioengineering and Biotechnology, 2020, ISSN 2296-4185
Editore: FRONTIERS MEDIA SA
DOI: 10.3389/fbioe.2020.576969

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