mitoFOIE GRAS: Non-invasive Profiling of Mitochondrial Function in Non-Alcoholic Fatty Liver Disease

Deliverables

Websites, patent fillings, videos etc. (1)

Project Website and social media

Project Website and social media

Documents, reports (1)

Pinpointed putative novel biomarkers and advanced methodologies.

Pinpointed putative novel biomarkers and advanced methodologies.

Publications

Peer reviewed articles (6)

Mitochondria in non-alcoholic fatty liver disease

Author(s): Inês C.M. Simões, Adriana Fontes, Paolo Pinton, Hans Zischka, Mariusz R. Wieckowski
Published in: The International Journal of Biochemistry & Cell Biology, Issue 95, 2018, Page(s) 93-99, ISSN 1357-2725
DOI: 10.1016/j.biocel.2017.12.019

Dipeptidyl Peptidase-4 Is a Pro-Recovery Mediator During Acute Hepatotoxic Damage and Mirrors Severe Shifts in Kupffer Cells

Author(s): Nádia Duarte, Inês Coelho, Denys Holovanchuk, Joana Inês Almeida, Carlos Penha-Gonçalves, Maria Paula Macedo
Published in: Hepatology Communications, Issue 2/9, 2018, Page(s) 1080-1094, ISSN 2471-254X
DOI: 10.1002/hep4.1225

Targeting mitochondria to oppose the progression of nonalcoholic fatty liver disease

Author(s): Ignazio Grattagliano, Liliana P. Montezinho, Paulo J. Oliveira, Gema Frühbeck, Javier Gómez-Ambrosi, Fabrizio Montecucco, Federico Carbone, Mariusz R. Wieckowski, David Q.-H. Wang, Piero Portincasa
Published in: Biochemical Pharmacology, Issue 160, 2019, Page(s) 34-45, ISSN 0006-2952
DOI: 10.1016/j.bcp.2018.11.020

Self-Paced Free-Running Wheel Mimics High-Intensity Interval Training Impact on Rats’ Functional, Physiological, Biochemical, and Morphological Features

Author(s): Jorge Beleza, João Albuquerque, Estela Santos-Alves, Pedro Fonseca, Garoa Santocildes, Jelena Stevanovic, Sílvia Rocha-Rodrigues, David Rizo-Roca, António Ascensão, Joan Ramon Torrella, José Magalhães
Published in: Frontiers in Physiology, Issue 10, 2019, ISSN 1664-042X
DOI: 10.3389/fphys.2019.00593

A Diet Induced Maladaptive Increase in Hepatic Mitochondrial DNA Precedes OXPHOS Defects and May Contribute to Non-Alcoholic Fatty Liver Disease

Author(s): Malik, Simões, Rosa, Khan, Karkucinska-Wieckowska, Wieckowski
Published in: Cells, Issue 8/10, 2019, Page(s) 1222, ISSN 2073-4409
DOI: 10.3390/cells8101222

Fat and Sugar—A Dangerous Duet. A Comparative Review on Metabolic Remodeling in Rodent Models of Nonalcoholic Fatty Liver Disease

Author(s): Simoes, Janikiewicz, Bauer, Karkucinska-Wieckowska, Kalinowski, Dobrzyń, Wolski, Pronicki, Zieniewicz, Dobrzyń, Krawczyk, Zischka, Wieckowski, Potes
Published in: Nutrients, Issue 11/12, 2019, Page(s) 2871, ISSN 2072-6643
DOI: 10.3390/nu11122871