Publications Peer reviewed articles (23) A multiproducer microbiome generates chemical diversity in the marine sponge Mycale hentscheli Author(s): Michael Rust; Eric J. N. Helfrich; Michael F. Freeman; Pakjira Nanudorn; Christopher M. Field; Christian Rückert; Tomas Kündig; Michael J. Page; Victoria L. Webb; Jörn Kalinowski; Shinichi Sunagawa; Jörn Piel Published in: Proceedings of the National Academy of Sciences of the United States of America, Issue 2, 2020, ISSN 0027-8424 Publisher: National Academy of Sciences DOI: 10.3929/ethz-b-000413997 Modular Halogenation, α-Hydroxylation, and Acylation by a Remarkably Versatile Polyketide Synthase Author(s): Dr. Franziska Hemmerling,Dr. Roy A. Meoded,Dr. Amy E. Fraley,Hannah A. Minas,Cora L. Dieterich,Dr. Michael Rust,Dr. Reiko Ueoka,Dr. Katja Jensen,Prof. Dr. Eric J. N. Helfrich,Cedric Bergande,Maurice Biedermann,Dr. Nancy Magnus,Prof. Dr. Birgit Piechulla, Prof. Jörn Piel Published in: Angewandte Chemie International Edition, 2022, ISSN 1433-7851 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/anie.202116614 Comparative Genomics Underlines Multiple Roles of Profftella, an Obligate Symbiont of Psyllids: Providing Toxins, Vitamins, and Carotenoids. Author(s): Atsushi Nakabachi; Jörn Piel; Igor Malenovský; Yuu Hirose Published in: Genome Biology and Evolution, Issue 17596653, 2020, Page(s) 1975–1987, ISSN 1759-6653 Publisher: Oxford University Press DOI: 10.3929/ethz-b-000451415 In Vivo Production of Diverse beta-Amino Acid-Containing Proteins Author(s): Edgars Lakis; Sarolt Magyari; Jörn Piel Published in: Angewandte Chemie. International Edition, 61 (29), Issue 14337851, 2022, Page(s) e202202695, ISSN 1433-7851 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/ange.202202695 Toblerols, Cyclopropanol-Containing Modulators of Methylobacterial Antibiosis Generated by an Unusual Polyketide Synthase Author(s): Ueoka, Reiko Bortfeld-Miller, Miriam Morinaka, Brandon I. Vorholt, Julia A. Piel, Jörn Published in: Angewandte Chemie (international Edition), 2017, ISSN 1433-7851 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/anie.201709056 Genome-based discovery and total synthesis of janustatins, potent cytotoxins from a plant-associated bacterium Author(s): Reiko Ueoka, Philipp Sondermann, Stefan Leopold-Messer, Yizhou Liu, Rei Suo, Agneya Bhushan, Lida Vadakumchery, Ute Greczmiel, Yoko Yashiroda, Hiromi Kimura, Shinichi Nishimura, Yojiro Hoshikawa, Minoru Yoshida, Annette Oxenius, Shigeki Matsunaga, R. Thomas Williamson, Erick M. Carreira, Jörn Piel Published in: Nature Chemistry, Issue 17554330, 2022, ISSN 1755-4330 Publisher: Nature Publishing Group DOI: 10.1038/s41557-022-01020-0 Engineering the stambomycin modular polyketide synthase yields 37-membered mini-stambomycins Author(s): Li Su, Laurence Hôtel, Cédric Paris, Clara Chepkirui, Alexander O Brachmann, Jörn Piel, Christophe Jacob, Bertrand Aigle, Kira J Weissman Published in: Nature Communications, Issue 20411723, 2022, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-022-27955-z Opening up the Single‐Cell Toolbox for Microbial Natural Products Research Author(s): Jackson K. B. Cahn; Jörn Piel Published in: Angewandte Chemie International Edition, Issue 14337851, 2021, Page(s) 18412-18428, ISSN 1433-7851 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/anie.201900532 Genome Mining of Oxidation Modules in trans ‐Acyltransferase Polyketide Synthases Reveals a Culturable Source for Lobatamides Author(s): Reiko Ueoka, Roy A. Meoded, Alejandro Gran‐Scheuch, Agneya Bhushan, Marco W. Fraaije, Jörn Piel Published in: Angewandte Chemie International Edition, Issue 59/20, 2020, Page(s) 7761-7765, ISSN 1433-7851 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/anie.201916005 A Polyketide Synthase Component for Oxygen Insertion into Polyketide Backbones Author(s): Meoded, Roy A.; Ueoka, Reiko; Helfrich, Eric J. N.; Jensen, Katja; Magnus, Nancy; Piechulla, Birgit; Piel, Jörn Published in: Angewandte Chemie (International Ed. in English), Issue 1, 2018, ISSN 1433-7851 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/ange.201805363 A Polyketide Synthase Component for Oxygen Insertion into Polyketide Backbones Author(s): Roy A. Meoded, Reiko Ueoka, Eric J. N. Helfrich, Katja Jensen, Nancy Magnus, Birgit Piechulla, Jörn Piel Published in: Angewandte Chemie International Edition, Issue 57/36, 2018, Page(s) 11644-11648, ISSN 1433-7851 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/anie.201805363 Bipartite interactions, antibiotic production and biosynthetic potential of the Arabidopsis leaf microbiome Author(s): Eric J. N. Helfrich, Christine M. Vogel, Reiko Ueoka, Martin Schäfer, Florian Ryffel, Daniel B. Müller, Silke Probst, Markus Kreuzer, Jörn Piel, Julia A. Vorholt Published in: Nature Microbiology, Issue 3/8, 2018, Page(s) 909-919, ISSN 2058-5276 Publisher: Nature Research DOI: 10.1038/s41564-018-0200-0 Natural noncanonical protein splicing yields products with diverse β-amino acid residues Author(s): Brandon I. Morinaka, Edgars Lakis, Marjan Verest, Maximilian J. Helf, Thibault Scalvenzi, Anna L. Vagstad, James Sims, Shinichi Sunagawa, Muriel Gugger, Jörn Piel Published in: Science, Issue 359/6377, 2018, Page(s) 779-782, ISSN 0036-8075 Publisher: American Association for the Advancement of Science DOI: 10.1126/science.aao0157 Genome-Based Identification of a Plant-Associated Marine Bacterium as a Rich Natural Product Source Author(s): Reiko Ueoka, Agneya Bhushan, Silke I. Probst, Walter M. Bray, R. Scott Lokey, Roger G. Linington, Jörn Piel Published in: Angewandte Chemie International Edition, Issue 57/44, 2018, Page(s) 14519-14523, ISSN 1433-7851 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/anie.201805673 Structural and Functional Studies of a Pyran Synthase Domain from a trans -Acyltransferase Assembly Line Author(s): Drew T. Wagner, Zhicheng Zhang, Roy A. Meoded, Alexis J. Cepeda, Jörn Piel, Adrian T. Keatinge-Clay Published in: ACS Chemical Biology, Issue 13/4, 2018, Page(s) 975-983, ISSN 1554-8929 Publisher: American Chemical Society DOI: 10.1021/acschembio.8b00049 Opening up the Single-Cell Toolbox for Microbial Natural Products Research Author(s): Jörn Piel, Jackson Cahn Published in: Angewandte Chemie International Edition, 2019, ISSN 1433-7851 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/anie.201900532 Automated structure prediction of trans-acyltransferase polyketide synthase products Author(s): Eric J. N. Helfrich, Reiko Ueoka, Alon Dolev, Michael Rust, Roy A. Meoded, Agneya Bhushan, Gianmaria Califano, Rodrigo Costa, Muriel Gugger, Christoph Steinbeck, Pablo Moreno, Jörn Piel Published in: Nature Chemical Biology, Issue 15/8, 2019, Page(s) 813-821, ISSN 1552-4450 Publisher: Nature Publishing Group DOI: 10.1038/s41589-019-0313-7 Effect of tolytoxin on tunneling nanotube formation and function Author(s): Aysegul Dilsizoglu Senol, Anna Pepe, Clara Grudina, Nathalie Sassoon, Ueoka Reiko, Luc Bousset, Ronald Melki, Jörn Piel, Muriel Gugger, Chiara Zurzolo Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/s41598-019-42161-6 Genome mining- and synthetic biology-enabled production of hypermodified peptides Author(s): Agneya Bhushan, Peter J. Egli, Eike E. Peters, Michael F. Freeman, Jörn Piel Published in: Nature Chemistry, Issue 11/10, 2019, Page(s) 931-939, ISSN 1755-4330 Publisher: Nature Publishing Group DOI: 10.1038/s41557-019-0323-9 The hidden enzymology of bacterial natural product biosynthesis Author(s): Thomas A. Scott, Jörn Piel Published in: Nature Reviews Chemistry, Issue 3/7, 2019, Page(s) 404-425, ISSN 2397-3358 Publisher: Nature Research DOI: 10.1038/s41570-019-0107-1 Structure of a Promiscuous Thioesterase Domain Responsible for Branching Acylation in Polyketide Biosynthesis Author(s): Amy E. Fraley, Cora L. Dieterich, Mathijs F. J. Mabesoone, Hannah A. Minas, Roy A Meoded, Franziska Hemmerling, Jörn Piel Published in: Angewandte Chemie International Edition, Issue 14337851, 2022, ISSN 1433-7851 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/anie.202206385 Evolution of combinatorial diversity in trans-acyltransferase polyketide synthase assembly lines across bacteria Author(s): Eric J. N. Helfrich, Reiko Ueoka, Marc G. Chevrette, Franziska Hemmerling, Xiaowen Lu, Stefan Leopold-Messer, Hannah A. Minas, Adrien Y. Burch, Steven E. Lindow, Jörn Piel & Marnix H. Medema Published in: Nature Communications, 2021, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-021-21163-x Strategies to access biosynthetic novelty in bacterial genomes for drug discovery Author(s): Franziska Hemmerling; Jörn Piel Published in: Nature Reviews Drug Discovery, 21 (5), Issue 14741776, 2022, ISSN 1474-1776 Publisher: Nature Publishing Group DOI: 10.1038/s41573-022-00414-6 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
